著者

池田 一成 杉森 光子 川崎 一輝 黒川 博 錐本 忠市

出版者

JAPANESE SOCIETY FOR TUBERCULOSIS

雑誌

結核 (ISSN:00229776)

巻号頁・発行日

vol.67, no.10, pp.653-658, 1992

被引用文献数

1

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Twelve children who developed active tuberculosis even after receiving isoniazid (INH) chemoprophylaxis were seen at Tokyo Metropolitan Children's Hospital from 1982 through 1991. All cases received INH more than 9mg/kg/day, except for one case in which the amount of INH administered at the referring hospital was unknown and Streptomycin was administered together with INH. The age of starting INH prophylaxis ranged from 2 months to 13 years, and the age at which clinical symptoms and/or laboratory evidences of active tuberculosis were first manifested ranged from 4 months to 18 years. Five patients developed active tuberculosis after the completion of chemoprophylaxis and patients during chemoprophylaxis, with the first presentation ranging from primary complex (seven), chronic pulmonary tuberculosis (two), tuberculous meningitis (two), and tuberculous pleuritis (one). None of the Mycobacterium tuberculosis resistant to INH was isolated.<BR>Reviewing these patients, eleven cases had at least one of the following factors: (1) age less than two years old (2) infectious sources expectorated more Mycobacterium tuberculosis (3) delay in starting INH. Above factors should be considered in initiating INH chemopro phylaxis and subsequent follow-up of the patients.

著者

阿美古 理恵

出版者

国際浮世絵学会

雑誌

浮世絵芸術 (ISSN:00415979)

巻号頁・発行日

no.157, pp.12-31, 2009

著者

根木 昭

出版者

日本音楽芸術マネジメント学会

雑誌

音楽芸術マネジメント

巻号頁・発行日

no.1, pp.37-44, 2009

著者

北條 秀衛

出版者

日本音楽芸術マネジメント学会

雑誌

音楽芸術マネジメント

巻号頁・発行日

no.3, pp.40-45, 2011

著者

山内 亮平

巻号頁・発行日

2011

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筑波大学博士 (スポーツ医学) 学位論文・平成23年4月30日授与 (甲第5880号)

著者

齋藤 和人 曾田 雅満 寺田 文子

出版者

鹿屋体育大学

雑誌

学術研究紀要 (ISSN:13426613)

巻号頁・発行日

vol.14, pp.37-43, 1995-10

著者

Kenichiro Yaita Takumitsu Suzuki Yukihiro Yoshimura Natsuo Tachikawa

出版者

一般社団法人 日本内科学会

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

vol.51, no.22, pp.3231-3232, 2012 (Released:2012-11-15)

参考文献数

2

被引用文献数

2 2 2

著者

京都大学経済学部藤井ゼミナール論文編集委員会

出版者

京都大学経済学部藤井ゼミナール論文編集委員会

雑誌

藤月会論集

巻号頁・発行日

vol.20, 2011-02

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この論文はM&Aが企業に与えるパフォーマンス効果を明らかにするものである。分析の対象とした企業は製造業(機械、電気機器業界)と非製造業(サービス、ソフト・情報、運輸倉庫業界)に属する日本の企業である。分析の結果、M&A実施企業は実施翌年度において非実施企業よりROAやROEなどが高いことが分かった。さらに、この分析ではM&Aを行う企業が元々優れた業績を残す属性がある可能性を排除しきれないため、M&A実施企業において実施前と実施後の業績を比較し業績改善効果を分析した。その際、分析結果が業界によって異なることから、製造業と非製造業のそれぞれにおけるM&Aのパフォーマンス効果の特性を分析することとなった。この分析から、 (1) 製造業では1、2年という期間では業績の改善結果が見られず、業績改善を長期間に見据えている可能性があること (2) 非製造業ではROAや売上高増加率が改善する一方、販管費率が悪化することが明らかになった。

著者

Akihiro OHNISHI Tomohiro OSAKI Yoshiharu MATAHIRA Takeshi TSUKA Tomohiro IMAGAWA Yoshiharu OKAMOTO Saburo MINAMI

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.12-0240, (Released:2012-11-15)

被引用文献数

3 24

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The aim of this study was to investigate the correlations of severity of osteoarthritis (OA) and serum biomarkers including keratan sulfate (KS), hyaluronic acid (HA), and chondroitin sulfate (CS) 846 epitope. We also investigated the effect of glucosamine and fish collagen peptide (FCP) on OA. OA was induced in 12 rabbits (12 weeks of age) by anterior cruciate ligament transection (ACLT). After the surgery, the rabbits were orally administered FCP (F group), glucosamine (G group), or FCP and glucosamine (FG group) for 4 weeks. The control group was provided water ad libitum (C group). Blood was collected before surgery (pre-ACLT) and before euthanasia (post-ACLT) for serum marker measurement. Biomarker levels were measured by using commercial kits. We evaluated OA severity both macroscopically and histologically. Macroscopic evaluation showed mildly eroded condylar surfaces in the C group. Histological findings were significantly different from the FG and other groups. There were no significant differences between each group at post-ACLT in serum KS, HA and CS 846. Histological assessment and serum biomarker measurements performed at post- ACLT showed a significant correlation between HA concentration and OA severity. Variations in the CS 846 concentration at pre- and post-ACLT were significantly correlated with OA severity. Administration of glucosamine and FCP had chondroprotective effects in the ACLT model. Serum biomarker concentrations were significantly correlated with cartilage injury. Serum biomarker measurement would be useful for monitoring articular cartilage damage in the clinical setting.

著者

Wirasak FUNGFUANG Nobuhiko NAKAO Tomoaki NAKADA Makoto YOKOSUKA Toru R. SAITO

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.12-0276, (Released:2012-11-15)

被引用文献数

3 5

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The puberty onset in mammals is tightly coupled to the animal’s nutritional and metabolic state. In present study, we evaluated the effects of high fat diet on leptin, adiponectin levels, leptin mRNA expression and puberty onset in female rats. On day 21, female rats were divided into 2 groups; Normal food (NF) and High fat food (HF). HF group shows significantly earlier (P<0.001) date of vaginal opening and lower body weight (P<0.001) than NF group. The rats with HF had a significantly heavier uterus (P<0.05) than NF, whereas serum leptin and adiponectin levels and leptin mRNA expression were not significant differences between NF and HF. We speculate that the fat-induced nutritional imbalance in young females may lead to neuroendocrine dysfunction during adolescence.

著者

国防科学研究会 著

出版者

亜細亜出版社

巻号頁・発行日

1938

著者

兵庫県防諜研究会 編

出版者

兵庫県防諜研究会

巻号頁・発行日

1938

著者

池田 一成 杉森 光子 川崎 一輝 黒川 博 雉本 忠市

出版者

JAPANESE SOCIETY FOR TUBERCULOSIS

雑誌

結核 (ISSN:00229776)

巻号頁・発行日

vol.67, no.9, pp.607-612, 1992

被引用文献数

1

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We evaluated the clinical and laboratory findings of tuberculous meningitis admitted to Tokyo Metropolitan Children's Hospital from 1980 through 1991 retrospectively. They consisted of 26 patients (14 boys and 12 girls), and their age ranged from 4 months to 11 years. Seventeen patients were under 3 years of age. Mortality rate was 4% (1/26), and there were 13 patients with sequelae on discharge from the hospital, and 12 patients without any sequelae. The period to recover normal CSF findings was relatively long. Some cases which did not seem to respond well to chemotherapy at the initial stage, recovered from meningitis without sequelae. This suggests that it is not necessary to change the chemo therapy at the initial few weeks of therapy. The risk factors of poor prognosis were age less than 2 years, decreased level of consciousness on admission, convulsion, CSF protein more than 70 mg/dl, and CSF glucose less than 20 mg/dl. Tryptophan reaction was not always positive. Chloride in CSF was not so important to diagnose tuberculous meningitis in children. For the proper diagnosis of tuberculous meningitis in children one should consider several factors such as tuberculin skin test, family history, chest X-ray findings and CSF study.<BR>BCG was inoculated in six children (three patients were under one year old and the rests were older than 4 years). In three patients under one year old BCG was seemed to be inoculated after Mycobacterium tuberculosis infection, and apparently not effective to prevent tuberculosis meningitis. We conclude that BCG vaccination is necessary in early infancy to prevent tuberculous meningitis.

著者

小中 陽太郎

出版者

中部大学

雑誌

言語文化研究 : 中部大学女子短期大学紀要 (ISSN:09158553)

巻号頁・発行日

vol.6, pp.45-55, 1995-03-01

著者

小野協一教授退官記念論集刊行委員会編

出版者

南雲堂

巻号頁・発行日

1984

著者

半藤 保 小林 正子 久保田 美雪

出版者

日本母性衛生学会

雑誌

母性衛生 (ISSN:03881512)

巻号頁・発行日

vol.48, no.1, pp.21-28, 2007-04

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大学生381人(男子100人,女子281人)に無記名アンケート方式により,性行動,性感染症に対する現況と知識,および意識について調査した。その結果,以下の点を明らかにした。1)初交年齢のピーク:男子16歳,女子17歳。2)18歳までの性交経験率:男子78.9%,女子76.1%。3)複数人の性パートナーをもつ割合:男子52.7%,女子56.4%。4)性感染症(STI)の種類について回答者の50%以下しか知らなかったもの:性器ヘルペス,淋病,B型肝炎,C型肝炎,尖形コンジローマ。5)性交時,必ずコンドームを装着するもの:約2/3しかなく,1/3は「ときどき」あるいは「全く」装着しなかった。しかも,装着は避妊目的であって,STI予防を目的としたものは約20%にしか過ぎなった。6)STI予防のためコンドーム装着の必要性を自覚するもの:男子55%,女子80%。7)STI罹患疑いのとき,性パートナーともども病院を受診するとしたもの:39%。

著者

Yukiko Takao Yoshiyuki Miyazaki Fumitake Onishi Hideaki Kumihashi Yasuyuki Gomi Toyokazu Ishikawa Yoshinobu Okuno Yasuko Mori Hideo Asada Koichi Yamanishi Hiroyasu Iso

出版者

日本疫学会

雑誌

Journal of Epidemiology (ISSN:09175040)

巻号頁・発行日

vol.22, no.2, pp.167-174, 2012-03-05 (Released:2012-03-05)

参考文献数

33

被引用文献数

2 20

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Background: The incidence and risk factors for herpes zoster have been studied in cross-sectional and cohort studies, although most such studies have been conducted in Western countries. Evidence from Asian populations is limited, and no cohort study has been conducted in Asia. We are conducting a 3-year prospective cohort study in Shozu County in Kagawa Prefecture, Japan to determine the incidence and predictive and immunologic factors for herpes zoster among Japanese.Methods: The participants are followed for 3 years, and a telephone survey is conducted every 4 weeks. The participants were assigned to 1 of 3 studies. Participants in study A gave information on past history of herpes zoster and completed health questionnaires. Study B participants additionally underwent varicella-zoster virus (VZV) skin testing, and study C participants additionally underwent blood testing. If the participants develop herpes zoster, we evaluate clinical symptoms, measure cell-mediated immunity and humoral immunity using venous blood sampling, photograph skin areas with rash, conduct virus identification testing by polymerase chain reaction (PCR) and virus isolation from crust sampling, and evaluate postherpetic pain.Results: We recruited 12 522 participants aged 50 years or older in Shozu County from December 2009 through November 2010. The participation rate was 65.7% of the target population.Conclusions: The present study is likely to provide valuable data on the incidence and predictive and immunologic factors for herpes zoster in a defined community-based population of Japanese.

著者

酒井 栄一 田中 勉 森 光子 中川原 寛一

出版者

日本電気泳動学会

雑誌

生物物理化学 = Journal of Electrophoresis (ISSN:00319082)

巻号頁・発行日

vol.45, no.1, pp.11-16, 2001-03-15

著者

松本 俊彦 今村 扶美

出版者

医学書院

雑誌

精神医学 (ISSN:04881281)

巻号頁・発行日

vol.51, no.9, pp.861-871, 2009-09

被引用文献数

1

著者

中山 貴樹

巻号頁・発行日

2012-03

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Supervisor:東条敏