著者
中村 勝範
出版者
慶應義塾大学法学研究会
雑誌
法学研究 (ISSN:03890538)
巻号頁・発行日
vol.66, no.1, pp.p9-43, 1993-01

米津昭子教授退職記念号一、問題の所在二、黎明会第七回講演会の背景三、福田徳三が危惧した労働者の急進化四、北沢新次郎における思想の二重構造五、三辺金蔵の英国的自由論からの立論六、麻生久のマルクス主義的革命論の立場七、吉野作造の普選論とそれにまつわる穿鑿八、結語
著者
新 良一 伊藤 幸惠 片岡 元行 原 宏佳 大橋 雄二 三浦 詩織 三浦 竜介 水谷 武夫 藤澤 倫彦
出版者
JAPAN BIFIDUS FOUNDATION
雑誌
腸内細菌学雑誌 (ISSN:13430882)
巻号頁・発行日
vol.28, no.1, pp.15-24, 2014

豆乳の発酵産物が宿主に及ぼす影響を検討した報告は少ない.今回,我々は豆乳の乳酸菌発酵産物(SFP: Soybean milk-Fermented Product)がヒト腸内細菌叢に及ぼす影響を検討し,さらに大腸の発がん予防とその作用機序についても合わせて検討した.SFPは豆乳を複数の乳酸菌と酵母で混合培養後殺菌し,凍結乾燥して調製した.一般的な日本食を食べているボランティアにSFPを摂取させ(450 mg/day/head for 14 days),腸内細菌叢の変化を比較したところ,SFP群はプラセボ群より<i>Bifidobacterium</i>の占有率が25%以上増加した人数が多かった(<i>P</i><0.05).さらに,昼食のみを一般的な日本食から肉食中心の欧米食(肉摂取量約300 g,900 kcal)に3日間変えると,<i>Clostridium</i>の占有率は増加したが(<i>P</i><0.05),SFPを摂取(900 mg/day/head)すると減少した(<i>P</i><0.05).また,SFPの摂取で<i>Bifidobacterium</i>の占有率が増加した(<i>P</i><0.05).このボランティアの糞便中<i>β</i>-glucuronidase活性は,昼食を肉食中心の欧米食にすると一般的な日本食摂取時より5倍以上増加したが(<i>P</i><0.01),SFP摂取で一般的な日本食時のレベルにまで減少した(<i>P</i><0.05).以上の結果は,SFPが多くのプロバイオティクスなどで示されている大腸がんの発がんリスクを軽減する可能性を示唆していると考え,以下の検討を試みた.即ち,SFPが大腸がんの発がんに及ぼす影響は大腸がん誘起剤1,2-dimethylhydrazine (DMH)をCF#1マウスに投与する化学発がんモデルを用いて検討した.SFPはDMH投与開始時から飼料中に3%(W/W)混和して与え,大腸に発がんした腫瘤数を検討した結果,有意な抑制が認められた(<i>P</i><0.05).一方,SFPの抗腫瘍作用機序は,Meth-A腫瘍移植モデルで検討した.SFP(10 mg/0.2 ml/day/head)は化学発がんモデルと同様にMeth-A腫瘍移植前から実験期間中投与し,抗腫瘍効果が得られた脾細胞を用いた Winn assayでその作用機序を検討した.その結果,SFP群のみは移植6日目以降でMeth-A単独移植群に比べ有意な腫瘍増殖抑制が認められ(<i>P</i><0.05),担癌マウスの脾細胞中に抗腫瘍作用を示す免疫細胞群が誘導された可能性が考えられた.<i>Bifidobacterium</i>を定着させたノトバイオートマウスは無菌マウスより脾細胞数が増加したが,無菌マウスにSFPや豆乳(10 mg/0.2 ml/day/head)を4週間連日経口投与しても,脾細胞数は生理食塩液を投与した無菌マウスと差が認められなかった.これらのことからSFPの抗腫瘍効果には腸内細菌が宿主免疫に関与した可能性が示唆されたが,その詳しい機序については今後の検討が必要である.<br>
著者
玉木 寛輝
出版者
慶應義塾大学大学院法学研究科内『法学政治学論究』刊行会
雑誌
法学政治学論究 : 法律・政治・社会 (ISSN:0916278X)
巻号頁・発行日
no.109, pp.137-168, 2016

一 はじめに二 大正期における「国務」の重要性の認識三 「国務」と「統帥」の調和から「政戦両略一体」の時代へ (一) 陸軍省軍務局軍事課予算班長時代 (二) 支那事変の勃発と「政戦両略一体」の模索四 総力戦研究所の設立と「政戦両略一体」の模索五 おわりに
著者
荒山 彰久
出版者
酣燈社
雑誌
航空情報 (ISSN:04506669)
巻号頁・発行日
vol.62, no.8, pp.100-103, 2012-08
著者
中野 良
出版者
公益財団法人史学会
雑誌
史學雜誌 (ISSN:00182478)
巻号頁・発行日
vol.114, no.4, pp.四九五-五一八, 2005-04-20

This article analyzes the problem of Japanese Army military exercises conducted during the Taisho Era, a topic to which the research to date on the Army has paid little attention. Nevertheless, such military exercises during that time were very important in the influence they exerted on various relations between the Army and local communities. The author first finds that the military exercises conducted by the Army's 13th Division met with difficulty due to a lack of interest in such activities on the part of residents around where the Division was stationed and their reluctance to supply the Army with recruits. The reason behind such difficulty was, according to the division commander, the tendency to conduct exercises repeatedly in the same area, leading to the suggestion that alternative regions be selected. Actually, alternating sites had been stipulated in the Army manual for military exercises, but the 13th Division had failed to comply with such regulations. Secondly, during that same time, the tactics being employed in military exercises had come under criticism among Army officers, who complained about contradictions in exercise planning and terrain, as well as in coordinating troop movements. Many suggestions were made as to how to improve the situation, but were not implemented, leading to the decision to repeat exercises in a given region and the dilemma encountered by the 13th Division and the local communities around it. Finally, the Army did take steps to correct the problem, such as loosening regulations concerning terrain and geographical conditions, thus increasing the number of regions where exercises could be conducted, in the hope of improving relations between Army divisions and local residents. Armament reductions also helped alleviate fixed military burdens, but in earnest solutions to the problems at hand were put off for later generations.
著者
大久保 文彦
出版者
公益財団法人史学会
雑誌
史學雜誌 (ISSN:00182478)
巻号頁・発行日
vol.103, no.6, pp.1059-1095, 1222-1224, 1994-06-20

In this article the author investigates the background and origins of the discharge of Inspector-General of Army Education Mazaki Jinzaburo in July 1935, which resulted in a dispute over army personnel. He focuses on 1)the three Army Chiefs Council (陸軍三長官会議), which was the scene of the discharge procedures, 2)the formation process of 1913 the Arrangement Regulating Duties of three Army Departments and 3)related the Agreement of three Chiefs. In the first chapter, the author analyzes the defense offered by Mazaki up to his discharge, showing, in contrast to conventional opinions, that his views concerning both the Council and the agreement related to the Arrangement surfaced just before the finale to the case. In chapter two, the author demonstrates how Army Minister Hayashi knowing of the Arrangement provision devised counter-measures on how to deal with the Council, intentionally ignoring the Agreement. In chapter three, the author traces the formation process of the Arrangement back to 1913, indicating that the Army Ministry bureaucratic reforms aimed at abolishing the ministerial appointment of active duty military officers was opposed by the Army. This opposition appeared in a revision of the ministerial duties item in provisions. This was the direct cause of the establishment of the Arrangement in the midst of peacetime institutional revisions that the Army feared would enable Imperial edicts to override military decrees. In chapter four, the author takes up the personnel aspect, showing the evolution within negotiations between the General Staff, who wanted to nominalize the authority of the Army Minister and a reluctant Army Ministry over a plan for a personnel section with the three chiefs to be the major decision makers. In opposition to the General Staff who wanted the establishment of such a section according to peace-time organization, the Army Ministry Personnel Bureau Appointments Section attempted to eliminate its effectiveness and authority. What happened in the end was the inevitable division in personnel affairs known in the research literature as "Addenda to Army Secret Memorandum No.120 : The A and B proposals". The "B Proposal", which contained many of the elements for a Personnel Section, should not have gone any farther than simple agreement between the three Chiefs and in fact the authority over the June petition to the throne was held by the Army Minister. But, being only a provisional action, the petition clearly asked for a decision to be made at a later date. After the promulgation of bureaucratic reforms and the consequent resignation of the Army Minister, the right to petition the throne was transferred to the Chief of General Staff, who thus had the last word on the final petition submitted in July. The research up till now has denied the effectiveness of the "B Proposal" on the grounds that its contents were missing from the final petition. However, at the June phase of the petition the "B Proposal" was clearly stated as a subordinate provision to the "A proposal" ; and if the July petition is considered to be a final decision concerning a revised "A Proposal", it is impossible to state for certain that the "B Proposal" was not also accepted. If we keep in mind the sense of urgency shown by the Army, the content of both the June and July petitions should be considered as one entity. Therefore acceptance was given to the June petition through a process that lasted until July. It is for this reason that the effectiveness of the "Agreement" between the three Chiefs cannot be refuted, and the three Army Chiefs Council, given elements of a Personnel section by this petition, became, as Mazaki Jinzaburo reasoned, a personnel decision making apparatus with each Chief having an equal say in the matter.
著者
玉井 清
出版者
慶應義塾大学法学研究会
雑誌
法学研究 (ISSN:03890538)
巻号頁・発行日
vol.62, no.9, pp.p56-86, 1989-09

論説序第一章 政府覚結成に対する牽制第二章 憲政会との提携許否の姿勢第三章 党内における硬軟両論の並存とその収拾過程第四章 陸軍及び山県との関係結語
著者
伊狩 章
出版者
新潟大学人文学部
雑誌
人文科学研究 (ISSN:04477332)
巻号頁・発行日
no.70, pp.p1-33, 1986-12