著者
Daisuke Nishioka Chisato Tamaki Noriko Furuita Hirokazu Nakagawa Erin Sasaki Rika Uematsu Takeshi Ozaki Satoshi Wakata Naoki Kondo
出版者
Japan Epidemiological Association
雑誌
Journal of Epidemiology (ISSN:09175040)
巻号頁・発行日
pp.JE20210005, (Released:2021-03-27)
参考文献数
24
被引用文献数
5

Background: The Free/Low-Cost Medical Care Program (FLCMC) can subsidize the payment (exempt/lower) in designated institutions in Japan. Given that poverty is a multidimensional concept including social isolation, the FLCMC applicants may need social support over and above financial aid to improve their quality of life. However, there was no data to discuss what services should be provided and to whom. Hence, we aimed to describe the changes in health-related quality of life scores among users of the FLCMC, with respect to their socioeconomic backgrounds.Methods: This cohort study included patients who newly used FLCMC from July 2018 to April 2019. We used patients’ social work records, obtained at baseline, and self-report questionnaires on the Medical Outcomes Study 8 Items Short Form Health Survey (SF-8), measured both at baseline and six-month-after the application. We used the change in physical and mental health component summary score (PCS-8 and MCS-8) as outcome variables.Results: Multiple linear regression analyses, adjusting for age, sex, healthcare institute, and baseline PCS-8 and MCS-8, showed that lower income was associated with an increase in PCS-8 (coef. -0.09; 95% CI, -0.15 to, -0.03) and MCS-8 (coef. -0.04; 95% CI, -0.11, to 0.03). Living alone (versus. living with someone) was potentially associated with a decrease in both PCS-8 (coef. -1.58; 95% CI, -7.26 to 4.09) and MCS-8 (coef. -3.62; 95% CI, -9.19 to 1.95).Conclusions: Among patients using FLCMC, those who live alone may need additional support. Further study testing the generalizability of the findings is required.
著者
Ryota Hase Rika Kurata Keiko Ishida Takashi Kurita Emiri Muranaka Haruki Mito
出版者
The Japanese Society of Internal Medicine
雑誌
Internal Medicine (ISSN:09182918)
巻号頁・発行日
pp.5377-20, (Released:2020-07-28)
参考文献数
10
被引用文献数
12

A 42-year-old man exhibiting hypoxia was diagnosed with coronavirus disease 2019. He had medical histories of type 2 diabetes, hyperlipidemia, hyperuricemia, and gout attack. He received favipiravir for compassionate use for 14 days. Subsequently, he showed increased uric acid levels and developed acute gouty arthritis. Favipiravir may induce not only hyperuricemia but also acute gouty arthritis. It should therefore be used with caution in patients with a history of gout and those with hyperuricemia, especially when used at a higher dose and for a longer duration than is typical.
著者
Satomi Ishihara Rika Kawakami Maki Nogi Kaeko Hirai Yukihiro Hashimoto Yasuki Nakada Hitoshi Nakagawa Tomoya Ueda Taku Nishida Kenji Onoue Tsunenari Soeda Satoshi Okayama Makoto Watanabe Yoshihiko Saito
出版者
The Japanese Circulation Society
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
pp.CJ-19-0620, (Released:2019-12-26)
参考文献数
30
被引用文献数
8

Background:Countermeasure development for early rehospitalization for heart failure (re-HHF) is an urgent and important issue in Western countries and Japan.Methods and Results:Of 1,074 consecutive NARA-HF study participants with acute decompensated HF admitted to hospital as an emergency between January 2007 and December 2016, we excluded 291 without follow-up data, who died in hospital, or who had previous HF-related hospitalizations, leaving 783 in the analysis. During the median follow-up period of 895 days, 241 patients were re-admitted for HF. The incidence of re-HHF was the highest within the first 30 days of discharge (3.3% [26 patients]) and remained high until 90 days, after which it decreased sharply. Within 90 days of discharge, 63 (8.0%) patients were re-admitted. Kaplan-Meier analysis revealed that patients with 90-day re-HHF had worse prognoses than those without 90-day re-HHF in terms of all-cause death (hazard ratio [HR] 2.321, 95% confidence interval [CI] 1.654–3.174; P<0.001) and cardiovascular death (HR 3.396, 95% CI 2.153–5.145; P<0.001). Multivariate analysis indicated that only male sex was an independent predictor of 90-day re-HHF.Conclusions:The incidence of early re-HHF was lower in Japan than in Western countries. Its predictors are not related to the clinical factors of HF, indicating that a new comprehensive approach might be needed to prevent early re-HHF.
著者
Kei Kikuchi Akiko Miki Hiroki Satoh Noriko Iba Rika Sato-Sakuma Hirokuni Beppu Yasufumi Sawada
出版者
International Research and Cooperation Association for Bio & Socio-Sciences Advancement
雑誌
Drug Discoveries & Therapeutics (ISSN:18817831)
巻号頁・発行日
vol.13, no.4, pp.183-188, 2019-08-31 (Released:2019-09-18)
参考文献数
13

Patient narratives of adverse drug events (ADEs) often differ from the symptoms listed on the package inserts of pharmaceutical products using common ADE terminology and could be a source of great comfort to patients with the same disease. To explore this idea, we analyzed written narratives obtained from 48 patients with breast cancer using the NPO Corporation Database of Individual Patients' Experiences, Japan (DIPEx-Japan). Our analysis aimed to determine the utility of an "Adverse Drug Event Database" for use in clinical settings as a novel source of disease information in patients' own words. An analysis of transcripts from 29 patients, in which they recounted their treatment drugs and the time of onset and duration of ADEs in great detail, revealed several discrepancies between the language they used to describe various side effects and the standard ADE terminology on package inserts. We conclude that the language used to describe ADEs on package inserts is insufficient for helping patients as they struggle to recognize, internalize, and overcome ADEs, and argue the need for available, detailed information in the words of real patients about the nature of the ADEs predicted, as well as their clinical course and duration. Such information would be invaluable in supplementing the standardized language used on package inserts. Databases of patients' narrative accounts of ADEs are needed as information sources that can be reliably disseminated among patients.
著者
木下 りか Rika KISHITA
出版者
大手前大学
雑誌
大手前大学人文科学部論集 = Otemae journal of humanities (ISSN:13462105)
巻号頁・発行日
vol.7, pp.A49-A59, 2006-03-31

語基を同じくし意味的な対応を持つ名詞と形容詞は、その意味を大きく変えることなく互換可能である。形状を表す「丸のN」「丸いN」、「四角のN」「四角いN」もその例である。このような名詞と形容詞の使い分けを見ると、名詞「丸のN」「四角のN」は、「コンテクストに存在するほかの形状との対比の中で、Nの性質(形状)について述べる」場合に用いられると考えることができる。「コンテクストに存在する他の形状との対比の中で」ということは、「丸のN」や「四角のN」における「丸」や「四角」が、丸や四角のモノを指示する機能を持つことを示している。このように考えることで、「丸のN」や「四角のN」が制限的修飾として用いられるが非制限的修飾には馴染まないこと、また、非制限的修飾であっても一定の文脈が与えられれば、すなわち客観的定義機能を持つ場合であれば用いることができることなど、これらに特有のふるまいが説明可能となる。
著者
今田 純雄 米山 理香 イマダ スミオ ヨネヤマ リカ Sumio Imada Rika Yoneyama
雑誌
広島修大論集. 人文編
巻号頁・発行日
vol.38, no.2, pp.493-507, 1998-03-30

本研究は,心理検査法(塩見・千葉・岸本,1988)の尺度構成法により,日本語版食物新奇性恐怖尺度の標準化を試みたものである。予備項目の選定,予備項目データの収拾と分析を行い,14項目から構成される1要因尺度を作成した。尺度の妥当性,信頼性とも高いものであり,食物新奇性恐怖の傾向を測定しうる尺度が得られたと考えられる。14項目版のみでデータを再度収拾したところ,逆転,非逆転の項目配置を反映した2因子が得られた。これは,項目配置に問題のあることを示している。今後の使用にあたっては,項目順を見直し,再度,尺度としての安定性について検討する必要があろう。
著者
Shogo DOFUKU Masayuki SATO Takashi AOKA Rika NAKAMURA Kenta OHARA Takahiro OTA
出版者
The Japan Neurosurgical Society
雑誌
NMC Case Report Journal (ISSN:21884226)
巻号頁・発行日
vol.10, pp.191-195, 2023-12-31 (Released:2023-06-26)
参考文献数
31

We report a rare case of isolated internal carotid artery occlusion complicated by central retinal artery occlusion that was successfully treated with mechanical thrombectomy for internal carotid artery occlusion. A 59-year-old man visited the emergency room because of right monocular blindness. Magnetic resonance imaging showed multiple acute small embolic infarctions in the right frontal lobe, and magnetic resonance angiography revealed right internal carotid artery occlusion without the associated occlusion of the circle of Willis, which indicates the patency of the anterior and middle cerebral arteries. An electrocardiogram showed atrial fibrillation. Therefore, we performed mechanical thrombectomy with a stent retriever under continuous manual aspiration with a balloon-guiding catheter and confirmed complete recanalization, anterograde flow in the right ophthalmic artery, and retinal brush. The procedure was completed without complications, and the patient noticed an improvement in visual acuity immediately after the procedure. When a patient with atrial fibrillation complains of monocular blindness, it is important to consider internal carotid artery occlusion due to cardioembolism, to perform an examination promptly, and to consider early treatment, including mechanical thrombectomy.
著者
Masato Ikegami Hitoshi Mutai Rika Karasawa Yoshie Yuzawa Nobuko Sakai
出版者
社団法人 日本作業療法士協会
雑誌
Asian Journal of Occupational Therapy (ISSN:13473476)
巻号頁・発行日
vol.19, no.1, pp.68-76, 2023 (Released:2023-04-05)
参考文献数
27

Background and Purpose: We introduced an intervention that aimed to improve upper limb use in daily life using Aid for Decision-making in Occupation Choice for Hand (ADOC-H), a monitoring and problem-solving technique, in addition to conventional occupational therapy for hospitalized patients with acute stroke. This pilot study examined the effectiveness of this intervention to improve paralyzed upper limb use in daily life and their motor function.Methods: This comparative study included 28 patients with acute stroke who underwent an intervention based on the ADOC-H process (ADOC-H group) and 155 participants from a previous study (control group). The paralytic arm participation measure (PPM; scores for eating and toileting items) was used to evaluate upper limb use in daily life, and the Stroke Impairment Assessment Set (SIAS; knee mouth [K-M] and finger flexion [F-F] tests) was used to evaluate upper limb motor function. The amount of change in these evaluations was compared between the two groups.Results: Using propensity score matching, 21 participants were allocated to each group. Comparing the two groups, significant improvements were observed in the ADOC-H group for all items, as shown by the scores for PPM total (P = 0.005, r = 0.43), eating (P = 0.035, r = 0.32), toileting (P = 0.004, r = 0.44), upper limb motor function (P = 0.001, r = 0.52), K-M (P = 0.014, r = 0.38), and F-F (P = 0.002, r = 0.48).Conclusion: This intervention process may be effective for improving the frequency of paralyzed upper limb use and upper limb motor function of the paralyzed upper limbs in patients with acute stroke.
著者
Haruka Ozaki Kohji Takemura Rika Kizawa Takeshi Yamaguchi Chinatsu Komiyama Masato Tachi Hirotaka Maruno Yuko Tanabe Koichi Suyama Yuji Miura
出版者
The Japanese Society of Internal Medicine
雑誌
Internal Medicine (ISSN:09182918)
巻号頁・発行日
pp.1453-22, (Released:2023-03-22)
参考文献数
12
被引用文献数
1

Aortitis is a rare adverse event associated with granulocyte colony-stimulating factor (G-CSF). Contrast-enhanced computed tomography (CECT) is widely used to diagnose G-CSF-associated aortitis. However, the usefulness of gallium scintigraphy for the diagnosis of G-CSF-associated aortitis is unknown. We herein report a set of pre- and post-treatment gallium scintigrams of a patient with G-CSF-associated aortitis. During the diagnosis, gallium scintigraphy revealed hot spots on the arterial walls that appeared inflamed on CECT. Both the CECT and gallium scintigraphy findings disappeared. Gallium scintigraphy can be a supportive diagnostic tool for G-CSF-associated aortitis, especially in patients with an impaired renal function or allergy to iodine contrast.
著者
Yasuki Nakada Rika Kawakami Shouji Matsushima Tomomi Ide Koshiro Kanaoka Tomoya Ueda Satomi Ishihara Taku Nishida Kenji Onoue Tsunenari Soeda Satoshi Okayama Makoto Watanabe Hiroyuki Okura Miyuki Tsuchihashi-Makaya Hiroyuki Tsutsui Yoshihiko Saito
出版者
The Japanese Circulation Society
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
vol.83, no.5, pp.1019-1024, 2019-04-25 (Released:2019-04-25)
参考文献数
22
被引用文献数
8 13

Background: Prognosis after acute decompensated heart failure (ADHF) is poor. An appropriate risk score that would allow for improved care and treatment of ADHF patients after discharge, however, is lacking. Methods and Results: We used 2 HF cohorts, the NARA-HF study and JCARE-CARD, as derivation and validation cohorts, respectively. The primary endpoint was all-cause death during the 2-year follow-up, excluding in-hospital death. Age, hemoglobin (Hb), and brain natriuretic peptide (BNP) at discharge were identified as independent risk factors. We determined 3 categorizations on the basis of these parameters, termed A2B score: age (<65 years, 0; 65–74 years, 1; ≥75 years, 2), anemia (Hb <10 g/dL, 2; 10–11.9 g/dL, 1; ≥12 g/dL, 0) and BNP (<200 pg/mL, 0; 200–499 pg/mL, 1; ≥500 pg/mL, 2). We divided patients into 4 groups according to A2B score (extremely low, 0; low, 1–2; medium, 3–4; high, 5–6). For the extremely low-risk group, the 2-year survival rate was 97.8%, compared with 84.5%, 66.1%, and 45.2% for the low-, medium-, and high-risk groups, respectively. Using the JCARE-CARD as a validation model, for the extremely low-risk group, the 2-year survival was 95.4%, compared with 90.2%, 75.0%, and 55.6% for the low-, medium-, and high-risk groups, respectively. Conclusions: The user-friendly A2B score is useful for estimating survival rate in ADHF patients at discharge.
著者
柏木 理佳 カシワギ リカ Rika Kashiwagi
雑誌
嘉悦大学研究論集
巻号頁・発行日
vol.51, no.2, pp.1-16, 2008-12-19

わが国において少子高齢化にともない労働力不足が懸念される中、女性の労働力が注目されている。しかしながら近年の雇用の格差による環境の悪化は、より女性に多くのしわ寄せがきている。女性における労働市場において学歴インフレによる需要と供給のミスマッチが問題視され、世界から指摘されている。若い時期にだけ働いてくれればいいといった日本企業による女性の雇用方法が根強く残っている。中国企業では採用する際に女性の年齢や外見だけにとらわれることは少なく、同じ仏教を信仰する文化を持つ国でありながら日本とは違う欧米型の女性の雇用形態となっている。しかし中国においても企業や国の取り組みは、一概に日本より恵まれている環境にあるとはいえない。特に女性特有の職業においては必ずしも中国企業の採用方法が日本企業と大きく違うとは言い切れない。日中の差は、個人のキャリアアップへの意識において中国人女性の方が強いといえる。個人のリカレント教育やキャリア教育においてはいずれも十分とはいえないが、少なくとも職業意識においては大学生の段階からすでに構築している人の割合が中国人女性の方が多い。日中の比較を通して個人における女性のリカレント教育を分析し若干の示唆をする。
著者
Hideto SHIRASAWA Chisato NISHIYAMA Rika HIRANO Takashi KOYANAGI Shujiro OKUDA Hiroki TAKAGI Shin KURIHARA
出版者
BMFH Press
雑誌
Bioscience of Microbiota, Food and Health (ISSN:21863342)
巻号頁・発行日
vol.42, no.1, pp.24-33, 2023 (Released:2023-01-01)
参考文献数
58
被引用文献数
1

It has been reported that the intake of polyamines contributes to the extension of healthy life span in animals. Fermented foods contain high concentrations of polyamines thought to be derived from fermentation bacteria. This suggests that bacteria that produce high levels of polyamines could be isolated from fermented foods and utilized as a source of polyamines for human nutrition. In this study, Staphylococcus epidermidis FB146 was isolated from miso, a Japanese fermented bean paste, and found to have a high concentration of putrescine in its culture supernatant (452 μM). We analyzed the presence of polyamines in the culture supernatants and cells of the type strains of 21 representative Staphylococcus species in addition to S. epidermidis FB146, and only S. epidermidis FB146 showed high putrescine productivity. Furthermore, whole-genome sequencing of S. epidermidis FB146 was performed, and the ornithine decarboxylase gene (odc), which is involved in putrescine synthesis, and the putrescine:ornithine antiporter gene (potE), which is thought to contribute to the release of putrescine into the culture supernatant, were present on plasmid DNA harbored by S. epidermidis FB146.
著者
Tomoya Ueda Rika Kawakami Manabu Horii Yu Sugawara Takaki Matsumoto Sadanori Okada Taku Nishida Tsunenari Soeda Satoshi Okayama Satoshi Somekawa Yukiji Takeda Makoto Watanabe Hiroyuki Kawata Shiro Uemura Yoshihiko Saito
出版者
The Japanese Circulation Society
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
vol.77, no.11, pp.2766-2771, 2013 (Released:2013-10-25)
参考文献数
29
被引用文献数
35 43

Background: Accumulating evidence suggests that hematopoiesis, especially erythropoiesis, is disturbed in heart failure (HF) for many reasons. Low hemoglobin and red blood cell distribution width have emerged as prognostic indicators of HF independent of classic predictors. The prognostic implication of mean corpuscular volume (MCV) in HF, however, is unknown. In this context, we investigated the relationship between MCV and prognosis of acute decompensated HF (ADHF). Methods and Results: This retrospective cohort study consisted of 458 consecutive patients with ADHF who had emergency admission to hospital. Patients were divided into 2 groups: MCV ≤100fl (non-macrocytic group, n=400); and MCV >100fl (macrocytic group, n=58). The relationship between MCV and all-cause death was tested using Cox proportional hazard models, adjusting for other predictors. Mean patient age was 72.4 years and mean MCV was 93.0±7.1fl. Hemoglobin was significantly lower in the macrocytic group than the non-macrocytic group. During the mean follow-up of 20.8 months, a total of 173 deaths (37.9%) occurred. Kaplan-Meier analysis showed that all-cause death was significantly higher in the macrocytic group (log-rank P<0.0001). Cox proportional hazards analysis indicated that macrocytosis was an independent predictor of all-cause death (hazard ratio, 2.288; 95% confidence interval: 1.390–3.643; P=0.0015) after adjustment in the multivariate model. Conclusions: It is proposed for the first time that MCV is an independent predictor of all-cause death in patients with ADHF.  (Circ J 2013; 77: 2766–2771)
著者
Daisuke Nishioka Chisato Tamaki Noriko Furuita Hirokazu Nakagawa Erin Sasaki Rika Uematsu Takeshi Ozaki Satoshi Wakata Naoki Kondo
出版者
Japan Epidemiological Association
雑誌
Journal of Epidemiology (ISSN:09175040)
巻号頁・発行日
vol.32, no.11, pp.519-523, 2022-11-05 (Released:2022-11-05)
参考文献数
24
被引用文献数
1 5

Background: The Free/Low-Cost Medical Care Program (FLCMC) can subsidize the payment (exempt/lower) in designated institutions in Japan. Given that poverty is a multidimensional concept including social isolation, the FLCMC applicants may need social support over and above financial aid to improve their quality of life. However, there was no data to discuss what services should be provided and to whom. Hence, we aimed to describe the changes in health-related quality of life scores among users of the FLCMC, with respect to their socioeconomic backgrounds.Methods: This cohort study included patients who newly used FLCMC from July 2018 to April 2019. We used patients’ social work records, obtained at baseline, and self-report questionnaires on the Medical Outcomes Study 8 Items Short Form Health Survey (SF-8), measured both at baseline and 6 months after the application. We used the change in physical and mental health component summary scores (PCS-8 and MCS-8, respectively) as outcome variables.Results: Multiple linear regression analyses, adjusting for age, sex, healthcare institute, and baseline PCS-8 and MCS-8, showed that lower income was associated with an increase in PCS-8 (coef. −0.09; 95% CI, −0.15 to, −0.03) and MCS-8 (coef. −0.04; 95% CI, −0.11, to 0.03). Living alone (versus living with someone) was potentially associated with a decrease in both PCS-8 (coef. −1.58; 95% CI, −7.26 to 4.09) and MCS-8 (coef. −3.62; 95% CI, −9.19 to 1.95).Conclusion: Among patients using FLCMC, those who live alone may need additional support. Further study testing the generalizability of the findings is required.
著者
野畑 理佳 Rika NOHATA
雑誌
武庫川女子大学紀要 (ISSN:24354848)
巻号頁・発行日
vol.68, pp.11-19, 2021-03-12

The purpose of this article is to report how affective factors including anxiety, self-confidence, risk-taking and inhibition change and how Willingness to Communicate in Japanese outside the classroom is affected by those factors while studying in Japan. The data was collected by interview and questionnaires to two advanced learners and analyzed by qualitative data analysis method. The results show that opportunities to perceive language competence, experiences of communication, features and participants of communication, and learnersʼ beliefs affect Willingness to Communicate. Successful communication enhance self-confidence and decrease language-use anxiety. Self-confidence influences Willingness to Communicate with significant others in the target language society. Experiences of failures in communication causes language use anxiety and decrease Willingness to Communicate with others. Conditions of communication also impacts their willingness to communicate, especially with significant others in the target community. The implication of the findings suggests Willingness to Communicate is concerned with the desire to establish a relationship with others as a member of the target community.
著者
Koshiro Kanaoka Satoshi Okayama Michikazu Nakai Yoko Sumita Kunihiro Nishimura Rika Kawakami Hiroyuki Okura Yoshihiro Miyamoto Satoshi Yasuda Hiroyuki Tsutsui Issei Komuro Hisao Ogawa Yoshihiko Saito
出版者
The Japanese Circulation Society
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
vol.83, no.5, pp.1025-1031, 2019-04-25 (Released:2019-04-25)
参考文献数
21
被引用文献数
31 46

Background: With aging of the population, the economic burden associated with heart failure (HF) is expected to increase. However, little is known about the hospitalization costs associated with HF in Japan. Methods and Results: In this cross-sectional study, using data from The Japanese Registry of All Cardiac and Vascular Diseases (JROAD) and JROAD-Diagnosis Procedure Combination databases between 2012 and 2014, we evaluated hospitalization costs for acute cardiovascular diseases (CVDs), including HF. A total of &#36;1,187 million/year (44% of the hospitalization costs for acute CVDs) was spent on patients with HF. We identified 273,865 patients with HF and the median cost per patient was &#36;8,089 (&#36;5,362–12,787) per episode. The top 1% of spenders accounted for 8% (&#36;80 million/year), and the top 5% of spenders accounted for 22% (&#36;229 million/year) of the entire cost associated with HF. The costs associated with HF for patients over 75 years of age accounted for 68% of the total cost. Conclusions: The costs associated with HF were higher than the hospitalization cost for any other acute CVD in Japan. Understanding how the total hospitalization cost is distributed may allow health providers to utilize limited resources more effectively for patients with HF.