著者

岡田 理香 オカダ リカ Rika Okada

雑誌

Derek

巻号頁・発行日

vol.37, pp.97-111, 2017

著者

Michikazu Nakai Yoshitaka Iwanaga Yoko Sumita Koshiro Kanaoka Rika Kawakami Masanobu Ishii Keiji Uchida Nobutaka Nagano Takeo Nakayama Kunihiro Nishimura Kazufumi Tsuchihashi Kazuo Kimura Yoshihiro Saito Kenichi Tsujita Hisao Ogawa Yoshihiro Miyamoto Satoshi Yasuda on the behalf of the JROAD Investigators

出版者

The Japanese Circulation Society

雑誌

Circulation Reports (ISSN:24340790)

巻号頁・発行日

vol.3, no.3, pp.131-136, 2021-03-10 (Released:2021-03-10)

参考文献数

25

被引用文献数

12 37

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Background:Big data systems such as diagnosis procedure combination (DPC) datasets have recently been used for research purposes. However, there have been few validation studies to determine the accuracy of diagnoses. The aim of this study was to validate and evaluate 2 diagnoses, namely acute myocardial infarction (AMI) and heart failure (HF), using International Classification of Diseases, 10th revision (ICD-10) codes in the Japanese Registry Of All cardiac and vascular Disease (JROAD)-DPC database.Methods and Results:ICD-10 codes I21.0–I21.9 and I50.0–I50.9 were used to identify AMI and HF, respectively, in the JROAD-DPC database. Diagnoses of AMI and HF were validated in clinical datasets assessing sensitivity and positive predictive value (PPV). Over 1–2 years, 742 patients hospitalized for AMI and 1,368 patients hospitalized for HF were identified in the DPC dataset. Sensitivity and PPV for AMI were 78.9% and 78.8%, respectively. When emergency hospitalization was included as a criterion, PPV increased to 84.9%. For HF, sensitivity and PPV were 84.7% and 57.0%, respectively. When emergency hospitalization and acute HF were included as criteria, PPV increased to 83.0%.Conclusions:Using ICD-10 codes for AMI and HF diagnoses among hospitalized patients, the DPC dataset showed acceptable concordance with clinical datasets. PPV increased when any conditions of hospitalization were included, especially in HF.

著者

岡田 理香 オカダ リカ Rika Okada

雑誌

Derek

巻号頁・発行日

vol.34, pp.43-64, 2014

著者

中塚 雅子 落合 利佳 Masako NAKATSUKA Rika OCHIAI わかば園保育士 京都文教短期大学 Wakaba en Kyoto Bunkyo Junior College

雑誌

京都文教短期大学研究紀要 = The Kenkyu kiyo (ISSN:03895467)

巻号頁・発行日

vol.47, pp.40-49, 2008-01-01

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保育園の現場でみられる発達障害の中でもとりわけアスペルガー症候群の子ども達を取り上げ、彼らに対する行事での支援について具体的にまとめて報告した。彼らを支援・援助していく上で大切なことは、可能な限り失敗体験や嫌悪体験をさせないことである。その意味では、運動会・お遊戯会といった園行事は、マイナス体験をしやすい場であり、見通しを持たせ、事前に十分に彼らにわかる形で様々な予告をするなどの支援が必要である。

著者

Tomoko Nakano Tomomi Kotani Yukio Mano Hiroyuki Tsuda Kenji Imai Takafumi Ushida Hua Li Rika Miki Seiji Sumigama Yoshiaki Sato Akira Iwase Akihiro Hirakawa Masato Asai Shinya Toyokuni Fumitaka Kikkawa

出版者

SOCIETY FOR FREE RADICAL RESEARCH JAPAN

雑誌

Journal of Clinical Biochemistry and Nutrition (ISSN:09120009)

巻号頁・発行日

vol.57, no.3, pp.178-182, 2015 (Released:2015-11-01)

参考文献数

33

被引用文献数

12 11

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Fetal brain injury is often related to prenatal inflammation; however, there is a lack of effective therapy. Recently, molecular hydrogen (H2), a specific antioxidant to hydroxyl radical and peroxynitrite, has been reported to have anti-inflammatory properties. The aim of this study was to investigate whether maternal H2 administration could protect the fetal brain against inflammation. Pregnant C3H/HeN mice received an intraperitoneal injection of lipopolysaccharide (LPS) on gestational day 15.5 and were provided with H2 water for 24 h prior to LPS injection. Pup brain samples were collected on gestational day 16.5, and the levels of apoptosis and oxidative damage were evaluated using immunohistochemistry. Interleukin-6 (IL-6) levels were examined using real-time PCR. The levels of apoptosis and oxidative damage, as well as the levels of IL-6 mRNA, increased significantly when the mother was injected with LPS than that in the control group. However, these levels were significantly reduced when H2 was administered prior to the LPS-injection. Our results suggest that LPS-induced apoptosis, oxidative damage and inflammation in the fetal brain were ameliorated by maternal H2 administration. Antenatal H2 administration might protect the premature brain against maternal inflammation.

著者

Jamsransuren Dulamjav Yoshii Kentaro Kariwa Hiroaki Asakawa Mitsuhiko Okuda Kei Fujii Kei Fukumoto Shinya Umemiya-Shirafuji Rika Sasaki Motoki Matsumoto Kotaro Yamaguchi Emi Ogawa Haruko Imai Kunitoshi

出版者

Faculty of Veterinary Medicine, Hokkaido University

雑誌

Japanese Journal of Veterinary Research (ISSN:00471917)

巻号頁・発行日

vol.67, no.2, pp.163-172, 2019-05

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The first human case of tick-borne encephalitis (TBE) in Japan was recorded in southern Hokkaido in 1993 and was followed by four further cases in southern, central, and northern Hokkaido during 2016-2018. However, the distribution of TBE virus (TBEV) foci in Japan is unclear. Therefore, here, we serologically examined raccoons (Procyon lotor), sika deer (Cervus nippon), and wild boars (Sus scrofa) as sentinels of TBEV infection in Hokkaido and in Fukushima and Tochigi Prefectures in Honshu. A total of 1,649 serum samples collected between 2003 and 2018 were screened by enzyme-linked immunosorbent assay using subviral particles and confirmed using the virus neutralization test. In raccoons, the seroprevalence of TBEV was 5.9% (39/662 samples) in central Hokkaido in 2003-2005 and 0.8% (3/368 samples) in eastern Hokkaido in 2010-2018, revealing the presence of TBEV foci in these areas. In addition, 0.5% (2/414) of deer sampled in eastern Hokkaido in 2010-2017 and 2.4% (1/42) of deer sampled in Tochigi Prefecture in 2016-2018 were seropositive. On Honshu, seropositive rodents have previously been detected only in Shimane Prefecture. Therefore, the detection of seropositive animals in Tochigi Prefecture may indicate the widespread distribution of TBEV foci throughout Japan. TBEV and viral genes were not detected in 507 ticks collected in the same area of eastern Hokkaido where seropositive animals were found, reemphasizing the value of using serological examination of wild animals as a tool for revealing unknown TBE risk areas. Our findings also indicate that raccoons may be particularly useful sentinels.

著者

Matsuo Rika Ochiai Keiji

出版者

Mammalogical Society of Japan

雑誌

Mammal study (ISSN:13434152)

巻号頁・発行日

vol.34, no.4, pp.187-194, 2009-12-01

参考文献数

48

被引用文献数

4

著者

町田 怜子 石川 一憲 川口 洋一 小嶋 隆治 保戸塚 里香 中森 千佳 福田 奈緒子 Reiko Machida Kazunori Ishikawa Yoichi Kawaguchi Ryuji Kojima Rika Hotozuka Chika Nakamori Naoko Fukuda

出版者

東京農業大学

雑誌

東京農業大学農学集報 = Journal of agriculture science, Tokyo University of Agriculture (ISSN:03759202)

巻号頁・発行日

vol.63, no.1, pp.42-48, 2018-06

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本研究では,東京農業大学農学分野の教員・技術員と幼稚園教諭とが連携し,野菜や果樹栽培の教育研究を活かした環境教育プログラムを試みた。本研究では,プログラムのねらいに応じて伊勢原農場内で教育素材を選定し,環境教育プログラムを実施した。環境教育プログラムでは,ステビア,レモングラス,コキアを五感で体験し植物の用途や効用を学ぶ環境教育プログラムを実施した。加えて,幼児が日常生活で親しんでいる野菜・果樹としてブドウ,ブルーベリー,ミニトマトの栽培技術や品種の違いを学ぶ環境教育プログラムを実施した。本プログラムの教育効果として,伊勢原農場の多様な果樹・野菜とその栽培技術は幼児たちに身近な野菜や果樹への発見,楽しさ,感動を与え,観察した物事を記録できる観察力や理解力の向上を確認できた。

著者

竹内 理樺 Rika Takeuchi

出版者

同志社大学言語文化学会

雑誌

言語文化 = Doshisha Studies in Language and Culture (ISSN:13441418)

巻号頁・発行日

vol.15, no.4, pp.359-389, 2013-03-10

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何香凝の芸術活動は一般にその政治活動と密接に結びつけて論じられる。しかし、1920年代末から40年代半ばまで、彼女は政治とは一線を画し、「一国民」として絵画の「義売」(慈善販売会)や兵士の救護活動を行い、画家の立場を立脚点として独自の抗日救国活動を行っていた。その活動は孫文と夫廖仲愷の遺志を継承する政治的理念に基づいたものであったため、多くの人々の支持を集め、結果的に彼女の名声と人望を高め、彼女を政治の第一線に復帰させることとなった。

著者

添田 梨香 上田 公代 SOEDA Rika UEDA Kimiyo

出版者

一般社団法人 日本女性心身医学会

雑誌

女性心身医学 = Journal of Japanese Society of Psychosomatic Obstetrics and Gynecology (ISSN:13452894)

巻号頁・発行日

vol.21, no.3, pp.306-313, 2016

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本研究では,妊娠中の「ストレス要因とそのストレス反応」について,その「ストレス対処」には「ソーシャルサポート」の強化,「生活満足度」や「心の健康度」の向上が有効に関連する,という概念枠組みのもと,相互の関連性を明らかにすることを目的とした.2011年4月25日~2012年3月9日,質問紙調査を行い,妊娠初期175名,中期207名,末期191名の計573名の妊婦を分析した.その結果,ストレス要因とその反応の得点は,妊娠3期別比較で有意差はなかった.ソーシャルサポートの実現度は,妊娠の全期間を通じて高い傾向にあり,生活満足度は初期より末期が有意に高く,夫に関連する満足度が高い傾向にあった.重回帰分析により,妊娠ストレスを低下させた要因は,生活満足度と心の疲労度(低い)であった.一方,妊娠ストレスを高めた要因は,日常ストレスであった.ストレス要因とストレス対処についての記述では,どちらも「夫」に関する内容が,それぞれ23.6%,33%と最も多く言及されており,夫に関することはストレス要因であり,同時にストレス対処要因と考えられた.</p><p> これらより,ストレス要因の緩和やストレス対処には,生活満足度の高揚と,心の疲労度(が低いこと)が重要であり,特に夫との関係性や夫のサポート力を高めることの重要性が示唆される.

著者

Masaru TERADA Ritsuko WATANABE Sousuke MASUI Ryoji MATOBA Tatsuo SHINOZUKA Rika NAKAJIMA Tatsuya MURAI Einosuke TANAKA Katsuya HONDA

出版者

The Japan Society for Analytical Chemistry

雑誌

Analytical Sciences/Supplements

巻号頁・発行日

pp.i1283-i1286, 2002 (Released:2007-03-13)

著者

Yoshinobu Morikawa Rika Kawakami Manabu Horii Yuta Yamamoto Matahiro Yabuta Yoshihiko Saito

出版者

International Heart Journal Association

雑誌

International Heart Journal (ISSN:13492365)

巻号頁・発行日

vol.62, no.1, pp.50-56, 2021-01-30 (Released:2021-01-30)

参考文献数

26

被引用文献数

3

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Diabetes mellitus (DM) is associated with an increased incidence of cardiovascular events and an elevated prevalence of sarcopenia. However, the relationship between cardiovascular events and sarcopenia in patients with DM remains unclear. This study examined this relationship and investigated the predictors of cardiovascular events in this population.This study enrolled 161 patients with DM and no history of cardiovascular diseases who were admitted to our hospital for the treatment of DM between September 2012 and December 2015. Patients were divided into sarcopenia and non-sarcopenia groups, and were followed until March 2019. The primary endpoint was major adverse cardiovascular events (MACE).The mean age was 65.9 ± 1.8 years old and the mean follow-up period was 4.1 ± 0.8 years. The log-rank test indicated that MACE differed significantly between the two groups (P < 0.0001). Multivariate Cox hazard analysis identified the cardio-ankle vascular index (CAVI) and handgrip strength as independent predictors of MACE (hazard ratio [HR] = 1.18, P = 0.039; and HR = 0.70, P = 0.016, respectively).Handgrip strength is an indicator of sarcopenia in diabetic patients, and together with CAVI it was independently associated with the incidence of MACE. This suggests that the handgrip strength test might be useful in the management of patients with DM at high risk of cardiovascular outcomes.

著者

Tetsuya Tagami Hironori Kimura Sumire Ohtani Tsuyoshi Tanaka Takashi Tanaka Shiro Hata Miho Saito Yasushi Miyazaki Rika Araki Masami Tanaka Kazuya Yonezawa Morio Sawamura Takuyuki Ise Atsushi Ogo Takuro Shimbo Akira Shimatsu Mitsuhide Naruse

出版者

The Japan Endocrine Society

雑誌

Endocrine Journal (ISSN:09188959)

巻号頁・発行日

vol.58, no.6, pp.449-457, 2011 (Released:2011-06-30)

参考文献数

44

被引用文献数

13 26

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Hypercholesterolemia is one of the most representative disorders of the common diseases. To evaluate the prevalence of hypothyroidism in the population of adult hypercholesterolemia, we prospectively examined the thyroid function in patients with untreated or treated hypercholesterolemia as a multi-center survey. Subjects were the patients who were treated with some antilipemic agents or the untreated patients whose total cholesterol (TC) was over 220 mg/dL and/or LDL-cholesterol (LDL-C) over 140 mg/dL. Among 737 cases recruited, 725 cases (300 males and 425 females) participated in the survey including the thyroid function test. The patient's backgrounds include hypertension (51%), diabetes mellitus (49%), fatty liver (17%), smoking (15%), and habitual drinking (10%). The 72% of the patients were treated with some antilipemic agents and the mean values of TC, LDL-C, triglyceride (TG), HDL-cholesterol (HDL-C), and LDL-C/HDL-C ratio (L/H) were 204.5 mg/dL, 119.6 mg/dL, 144.4 mg/dL, 60.7 mg/dL and 2.25, respectively. The primary hypothyroidism was seen in 27 cases (3.7%) (11 males, 16 females) with subclinical hypothyroidism in 17 cases (2.4%) and overt hypothyroidism in 10 cases (1.4%). The central hypothyroidism was seen in 4 cases (0.6%). The prevalence of hypothyroidism was 4.3% in patients with hypercholesterolemia. Taking account of the large number of patients with dyslipidemia and importance of avoiding unnecessary administration and associated adverse effects, evaluation of the thyroid function could be warranted in patients with dyslipidemia although cost-benefit issues waits further investigation.

著者

Motoki ENDO Yasuo HARUYAMA Takashi MUTO Mikio YUHARA Kenichi ASADA Rika KATO

出版者

National Institute of Occupational Safety and Health

雑誌

Industrial Health (ISSN:00198366)

巻号頁・発行日

vol.51, no.2, pp.165-171, 2013 (Released:2013-08-31)

参考文献数

33

被引用文献数

14 19

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There have been few epidemiological studies on recurrent sickness absence due to depression after returning to work (RTW). The objective of this study was to investigate the prognosis of workers who are RTW with depression in a Japanese company. This study employed a descriptive epidemiology study design. Subjects of this study were 540 employees who worked full-time and were registered in the Health Data System and returned to work from April 2002 to March 2008 after their first leave of absence due to depression. We investigated the recurrence of sickness absence due to depression after returning to work using the Kaplan-Meier survival curve method. During the 8.5 yr follow-up period, almost half of the RTW employees experienced recurrent sickness absence. There was a steep increase in recurrent rates the first two years after RTW, and 85.2% of total recurrence of sickness absence had occurred within three years after the index episode.

著者

Yuichi Tamura Rika Takeyasu Asuka Furukawa Hiromi Takada Mineki Takechi Hirohisa Taniguchi Akio Kawamura

出版者

The Japanese Circulation Society

雑誌

Circulation Reports (ISSN:24340790)

巻号頁・発行日

vol.2, no.9, pp.526-530, 2020-09-10 (Released:2020-09-10)

参考文献数

15

被引用文献数

6

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Background:COVID-19 is fatal to patients with pulmonary hypertension (PH), so preventive actions are recommended. This study investigated the effectiveness of telemedicine and effects on quality of life (QOL) in the treatment of patients with PH.Methods and Results:Japanese patients with PH (n=40) were recruited from one referral center. Patient self-reported anxiety worsened significantly and elderly patients in particular experienced detrimental lifestyle changes under COVID-19. Telemedicine worked well to decrease the frequency of going out.Conclusions:Telemedicine is effective in reducing travel distances, and frequent remote interventions may be desirable for older, anxious patients.

著者

Tetsuya TOBA Kouji YASUDA Toshiyuki NOHIRA Xiao YANG Rika HAGIWARA Koki ICHITSUBO Kenta MASUDA Takayuki HOMMA

出版者

The Electrochemical Society of Japan

雑誌

Electrochemistry (ISSN:13443542)

巻号頁・発行日

vol.81, no.7, pp.559-565, 2013-07-05 (Released:2013-07-05)

参考文献数

56

被引用文献数

19 31

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Direct electrolytic reduction of SiO2 was investigated in molten CaCl2 at 1123 K as a fundamental study to develop a continuous process for solar-grade Si production. Several different types of SiO2 granules, as well as SiO2 pellets, were successfully reduced to Si on the bottom cathode of a Si plate. Three parameters were varied in the reduction of SiO2 granules: electrode potential, layer thickness of the SiO2 granules, and SiO2 particle size. The reduction rate was evaluated by the magnitude of the reduction current. The main factor determining the reduction rate was the diffusion of O2− ions inside the reduced porous Si layer filled with the electrolyte. Another factor which influenced the reduction rate was the contact resistance between Si granules.

著者

Hisayoshi Araki Takeshi Yoshizako Rika Yoshida Mitsunari Maruyama Noriyoshi Ishikawa Hajime Kitagaki

出版者

Japanese Society for Magnetic Resonance in Medicine

雑誌

Magnetic Resonance in Medical Sciences (ISSN:13473182)

巻号頁・発行日

pp.ici.2019-0028, (Released:2019-05-07)

参考文献数

2

被引用文献数

1

著者

Nishigawa Keisuke Rodis Omar Marianito Maningo Matsuka Yoshizo Omoto Katsuhiro Hayama Rika Okura Kazuo Tajima Toyoko Suzuki Yoshitaka Hosoki Maki Shigemoto Shuji Ueda Mayu

出版者

社団法人 日本補綴歯科学会

雑誌

日本補綴歯科學會々誌 (ISSN:18831958)

巻号頁・発行日

vol.61, no.2, pp.217-222, 2017

被引用文献数

28

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Purpose: We previously investigated the effects of team-based learning (TBL) on fixed prosthodontic education and reported that TBL could have higher efficiency with high student satisfaction than traditional lecture. In the current report, we introduced flipped classroom to the fixed prosthodontic education and compared their effectiveness based on the final examination score in addition to TBL.Methods: Participants were forty-one students from XXXXXX University School of Dentistry who attended a fixed prosthodontics course. The first six classes adopted the flipped classroom style while the latter eight classes adopted TBL. To evaluate the relationship between learning styles and their effectiveness, we compared results from the term-end examination between the curriculum covered by flipped classroom and TBL-style classes. To draw comparisons, a referential examination with the same questions was conducted to eight faculty members who had not attended any of these classes.Results: Term-end examination results showed that TBL classes had slightly higher scores than flipped classroom classes. Referential examination results also showed higher scores for the same curriculum and no significant interaction was found between class formats and the term-end and referential examination scores. Analysis revealed no noticeable difference in the effectiveness of the class formats.Conclusion: Our previous study reported that TBL had higher efficiency than traditional style lecture. In the current study, there was no statistical difference in the examination score between flipped classroom and TBL. Therefore, we conclude that both styles are highly effective than traditional style lecture and constitute valid formats for clinical dental education.

著者

Takahiro Hayashi Saori Ikehata Haruna Matsuzaki Kimio Yasuda Toshiyasu Makihara Akihiko Futamura Yuki Arakawa Rika Kuki Kumiko Fukuura Hiroshi Takahashi Naoharu Mori Takashi Higashiguchi Shigeki Yamada

出版者

公益社団法人日本薬学会

雑誌

Biological and Pharmaceutical Bulletin (ISSN:09186158)

巻号頁・発行日

vol.37, no.12, pp.1860-1865, 2014-12-01 (Released:2014-12-01)

参考文献数

25

被引用文献数

3 7

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Morphine, oxycodone, and fentanyl are commonly used to control cancer pain. Because these drugs have differences in receptor affinity or pharmacokinetic parameters, changing the opioid formulation may result in an unexpected outcome, depending on the patient’s condition. This study investigated whether low serum protein levels influence the effectiveness of opioid rotation by determining the impact of serum albumin levels on the analgesic effect before and after opioid rotation from morphine or oxycodone to fentanyl in cancer patients. The patients were classified into 3 groups according to their serum albumin levels before opioid rotation: group 1, <2.5 g/dL; group 2, from 2.5 g/dL to <3.0 g/dL; and group 3, ≥3.0 g/dL. There was no significant change in the percentage of patients with good pain control after rotation in group 1 or group 2; however, the percentage of patients with good pain control increased significantly in group 3. When the percentage of patients whose numerical rating scale scores increased, were unchanged, or decreased after rotation were compared, a significant difference in the percentage of those showing improvement was noted among the 3 groups and between groups 1 and 3. These findings suggest that monitoring serum albumin levels during fentanyl therapy is useful for pain management, and that the effectiveness of opioid rotation to fentanyl in patients with serum albumin levels of <2.5 g/dL should be carefully evaluated after rotation.

著者

桐谷 広人 みきまる rika

出版者

日経BP社 ; 1985-

雑誌

日経マネー (ISSN:09119361)

巻号頁・発行日

no.370, pp.32-35, 2013-08

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2013年の日本株の買い場はいつか。著名ストラテジスト3氏の予想が上のグラフだ。3氏とも13年は年末に高値をとると見ており、高値メドは1万1000〜1万2000円だ。 理由は米国景気の回復。「量的緩和が続く結果、米国の経済成長率は年前半で1・5〜2%、年後半で2・5〜3%と上昇。リスク志向を高めた海外投資家が日本株も買う」(三菱UFJモルガン・スタンレー証券の藤戸則弘さん)。