著者

藤吉 好則

出版者

一般社団法人 日本生物物理学会

雑誌

生物物理 (ISSN:05824052)

巻号頁・発行日

vol.40, no.5, pp.299, 2000 (Released:2001-04-26)

著者

矢吹 貞人

出版者

一般社団法人 日本生物物理学会

雑誌

生物物理 (ISSN:05824052)

巻号頁・発行日

vol.21, no.5, pp.237-246, 1981-09-25 (Released:2009-05-25)

参考文献数

7

著者

四釜 慶治 松岡 有樹 菅原 芳明

出版者

一般社団法人日本生物物理学会

雑誌

生物物理 (ISSN:05824052)

巻号頁・発行日

vol.41, no.2, pp.74-79, 2001-03-25

被引用文献数

4

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The reversible and stable binding of dioxygen to the heme iron (II) is the basis of myoglobin and hemoglobin functions. During reversible oxygen binding, however, the oxygenated form of myoglobin or hemoglobin is oxidized easily to the ferric (III) met-form with generation of the superoxide anion. Thus, stability property of each oxygenated form is of particular importance in vivo, since the iron (III) species cannot bind dioxygen and is therefore physiologically inactive. With special emphasis on the possible roles of the distal histidine, this overview represents a compendium for the molecular mechanism of autoxidation for myoglobin and hemoglobin molecules.

著者

木原 裕 若林 克三

出版者

一般社団法人 日本生物物理学会

雑誌

生物物理 (ISSN:05824052)

巻号頁・発行日

vol.24, no.4, pp.178-182, 1984-07-25 (Released:2009-07-09)

参考文献数

13

著者

矢田 慶治 篠原 邦夫

出版者

一般社団法人 日本生物物理学会

雑誌

生物物理 (ISSN:05824052)

巻号頁・発行日

vol.33, no.4, pp.198-206, 1993-07-25 (Released:2009-07-09)

参考文献数

54

被引用文献数

1

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Developments in soft x-ray microscopy which has unique advantages in observation of biological samples are reviwed. Some types of the x-ray microscopes have now resolution better than 0.1μm, exceeding that of light microscope, and are capable of quick imaging of rather thick (1-10μm) hydrated samples with x-rays in the region of water window (2.3-4.3nm). Future problems related to radiation damage and thermal diffusion in observation of hydrated sample are briefly introduced.

著者

太田 元規 福地 佐斗志 小池 亮太郎

出版者

一般社団法人 日本生物物理学会

雑誌

生物物理 (ISSN:05824052)

巻号頁・発行日

vol.57, no.2, pp.085-089, 2017 (Released:2017-03-30)

参考文献数

16

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Protein-protein interactions are fundamental for all biological phenomena. The hub proteins interacting with a number of partner proteins play the vital role in the protein-protein interaction network. We investigated the subcellular localization of proteins in the network, and found that the proteins localized in the multiple subcellular compartments, especially the nucleus and cytoplasm, tend to be hub proteins. Examination on keywords associated with the proteins suggested that those related to post-translational modifications (PTMs) and transcriptions contributed to numerous interactions. Triggered by PTMs in the intrinsically disordered regions, they change interaction partners in the protein complex, and are translocated from cytoplasm to nucleus.

著者

中島 真人 牛木 辰男

出版者

一般社団法人 日本生物物理学会

雑誌

生物物理 (ISSN:05824052)

巻号頁・発行日

vol.53, no.1, pp.040-043, 2013 (Released:2013-01-29)

参考文献数

10

著者

小松 俊朗 北島 博己 吉原 透

出版者

The Biophysical Society of Japan General Incorporated Association

雑誌

生物物理 (ISSN:05824052)

巻号頁・発行日

vol.20, no.5, pp.297-305, 1980

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Recent studies of quantum chemical calculations on visual pigments are summerized.<BR>It is generally accepted that the red-shift and the wide distribution of λ<SUB>max'</SUB>s (wavelengths of absorption maximum) of visual pigments can be explained by the protonated Schiff-base binding of retinal with opsin and by the electrostatic interaction between retinal and a counter-ion on opsin. Experimental and theoretical evidences for this primary linkage and interaction are first presented and discussed.<BR>Secondly, recent studies of the secondary in teractions between retinal and opsin are summarized. At present, the following three types of the secondary interactions are mainly investigated: (1) the interaction of retinal through itsβ-ionone ring; (2) the interaction through its 9-methyl group; (3) the interaction with the local electric field due to the microenvironment of chromophore.<BR>Thirdly, as for the photochemical conversion of rhodopsin to bathorhodopsin, it is generally considered that retinal isomerizes from 11-cis to all-trans form. Concerning to the mechanism of this isomerization, the potential surfaces of the ground and excited states have recently been examined by several authors. Their models for the intermediates in photobleaching process are reviewed and discussed briefly.

著者

豊島 有 飯野 雄一

出版者

一般社団法人 日本生物物理学会

雑誌

生物物理 (ISSN:05824052)

巻号頁・発行日

vol.57, no.1, pp.020-022, 2017 (Released:2017-01-26)

参考文献数

9

著者

井上 剛 川原 茂敬 渡辺 恵 桐野 豊

出版者

一般社団法人日本生物物理学会

雑誌

生物物理 (ISSN:05824052)

巻号頁・発行日

vol.38, no.2, 1998-09-07

著者

水谷 泰久

出版者

一般社団法人日本生物物理学会

雑誌

生物物理 (ISSN:05824052)

巻号頁・発行日

vol.47, no.5, pp.288-294, 2007-09-25

参考文献数

25

被引用文献数

3 1

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In numerous biological processes, the ensuing protein structural changes accompanying a reaction at a specific site must spatially extend to the mesoscopic dimensions of the protein to achieve a biological function. The molecular mechanism of cooperativity in oxygen binding of hemoglobin is one of the classical problems in this aspect. This review describes our recent works on protein dynamics of myoglobin and hemoglobin by using time-resolved resonance Raman spectroscopy.<br>

著者

梅田 真郷 谷内 健太郎 稲留 弘乃 獅子王 信江 加藤 詩子

出版者

一般社団法人日本生物物理学会

雑誌

生物物理 (ISSN:05824052)

巻号頁・発行日

vol.45, no.1, 2005-10-19

出版者

一般社団法人 日本生物物理学会

雑誌

生物物理 (ISSN:05824052)

巻号頁・発行日

vol.52, no.5, pp.256-256, 2012 (Released:2012-09-26)

著者

赤松 友成

出版者

一般社団法人日本生物物理学会

雑誌

生物物理 (ISSN:05824052)

巻号頁・発行日

vol.38, no.4, pp.147-150, 1998-07

参考文献数

8

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Dolphins have bio-sonar ability called echoiocation. Clicks, echolocation signals, provide various biological information, such as, species, target range and acoustical survey effort of dolphins. Acoustical measurement is anewly developed method to observe underwater behavior of vocalizing animals.

著者

小嶋 誠司

出版者

一般社団法人日本生物物理学会

雑誌

生物物理 (ISSN:05824052)

巻号頁・発行日

vol.37, no.6, pp.273-275, 1997-11-01

出版者

一般社団法人 日本生物物理学会

雑誌

生物物理 (ISSN:05824052)

巻号頁・発行日

vol.54, no.3, pp.174-174, 2014 (Released:2014-05-27)

著者

田中 幸吉

出版者

一般社団法人 日本生物物理学会

雑誌

生物物理 (ISSN:05824052)

巻号頁・発行日

vol.20, no.2, pp.84-93, 1980-03-25 (Released:2009-05-25)

参考文献数

9

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This article is an introductory overview on artificial intelligence and its applications.The first section explains artificial intelligence and presents a bibliographical survey of related research and development works.The following section contains a brief review on some research topics together with perspectives obtained from a methodological view point.Lastly, some interesting and practical applications of artificial intelligence are illustrated along with the works of the present author.

著者

フーラハン 美由紀 吉村 珠美 川戸 佳 太田 善浩

出版者

一般社団法人日本生物物理学会

雑誌

生物物理 (ISSN:05824052)

巻号頁・発行日

vol.39, no.1, 1999-09-02

著者

武藤(細谷) 照子

出版者

一般社団法人 日本生物物理学会

雑誌

生物物理 (ISSN:05824052)

巻号頁・発行日

vol.27, no.2, pp.75-83, 1987-03-25 (Released:2009-05-25)

参考文献数

61

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The sex of an individual is determined at fertilization by the combination of sex chromosomes, e.g., XX or XY in mammals. Morphological sex differences become evident during the organization of gonadal primordia into ovaries or testes. Consequently, fetal testes produce hormones which are responsible for the development of the male phenotype. The absence of male hormones results in the development of the females phenotype. It has been proposed that a male dominant, histocompatibility-Y (H-Y) antigendetermines testicular differentiation, based on the finding that individuals with testest are H-Y antigen positive regardless of their sex karyotype. Recently, this hypothesis has been challenged bý the finding of several exceptions, e.g., development of ovaries in the presence of H-Y antigen, and testes in its absence.A testis-determining gene (Tdy or TDF) has been thought to occur on the Y chromosome. Over 100 Y-specific DNA fragments have been examined with only one possible candidate for the Tdy gene. In addition to the Tdy gene, at least two autosomal genes (tda-1 and Tas) appear to be involved in testis determination. It has been suggested that gonadal sex determination may also be influenced by environmental factors.Fetal rat and mouse ovaries develop testicular structures (ovotestes) after transplantation into various sites of adult host animals. This finding suggests that XX gonadal primordial cells can differentiate into testicular cells. Electron microscopic examinations have revealed that testicular structures of mouse ovotestes are comparable to those of the genetic male. Furthermore, it has been shown that ovotestes produce hormones and glycoproteins characteristic of normal neontal testes. These results provide strong evidence for sex reversal by transplantation. The study of the factors involved in the induction of ovotestis development should aid better understanding of the mechanism of gonadal sex determination.

著者

冨永 貴志 冨永 洋子

出版者

一般社団法人 日本生物物理学会

雑誌

生物物理 (ISSN:05824052)

巻号頁・発行日

vol.51, no.2, pp.092-095, 2011 (Released:2011-03-30)

参考文献数

10