ランキング (CiteULike) - Ceek.jp Altmetrics

7 0 0 0 A probabilistic atlas and reference system for the human brain : International Consortium for Brain Mapping (ICBM)

著者: MAZZIOTTA J.
雑誌: Philosophical Transactions of the Royal Society of London. Series B
巻号頁・発行日: vol.356, pp.1293-1322, 2001
被引用文献数: 4 1793

2018-09-10 15:29:22
6 CiteULike
1 + 0 Twitter

11 0 0 0 OA Amoebae Anticipate Periodic Events

著者: Saigusa Tetsu Tero Atsushi Nakagaki Toshiyuki Kuramoto Yoshiki
出版者: American Physical Society
雑誌: Physical Review Letters (ISSN:00319007)
巻号頁・発行日: vol.100, no.1, pp.018101, 2008-01-11
被引用文献数: 256 130

When plasmodia of the true slime mold Physarum were exposed to unfavorable conditions presented as three consecutive pulses at constant intervals, they reduced their locomotive speed in response to each episode. When the plasmodia were subsequently subjected to favorable conditions, they spontaneously reduced their locomotive speed at the time when the next unfavorable episode would have occurred. This implied the anticipation of impending environmental change. We explored the mechanisms underlying these types of behavior from a dynamical systems perspective.

7 0 0 0 OA Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist

著者: Haga Kazuko Kruse Andrew C. Asada Hidetsugu Yurugi-Kobayashi Takami Shiroishi Mitsunori Zhang Cheng Weis William I. Okada Tetsuji Kobilka Brian K. Haga Tatsuya Kobayashi Takuya
出版者: Nature Publishing Group
雑誌: Nature (ISSN:00280836)
巻号頁・発行日: 2012-01-25
被引用文献数: 663

認知症や心機能の抑制に関係する受容体の立体構造を世界で初めて解明-より効果的で副作用のない治療薬の探索・設計が可能に-. 京都大学プレスリリース.2012-01-26.

2016-10-19 22:00:40
5 CiteULike
2 + 0 Twitter

6 0 0 0 IR Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones

著者: Imanishi Tadashi Itoh Takeshi Suzuki Yutaka O'Donovan Claire Fukuchi Satoshi Koyanagi Kanako O. Barrero Roberto A. Tamura Takuro Yamaguchi-Kabata Yumi Tanino Motohiko Yura Kei Miyazaki Satoru Ikeo Kazuho Homma Keiichi Kasprzyk Arek Nishikawa Tetsuo Hirakawa Mika Thierry-Mieg Jean Thierry-Mieg Danielle Ashurst Jennifer Jia Libin Nakao Mitsuteru Thomas Michael A. Mulder Nicola Karavidopoulou Youla Jin Lihua Kim Sangsoo Yasuda Tomohiro Lenhard Boris Eveno Eric Suzuki Yoshiyuki Yamasaki Chisato Takeda Jun-ichi Gough Craig Hilton Phillip Fujii Yasuyuki Sakai Hiroaki Tanaka Susumu Amid Clara Bellgard Matthew Bonaldo Maria de Fatima Bono Hidemasa Bromberg Susan K. Brookes Anthony J. Bruford Elspeth Carninci Piero Chelala Claude Couillault Christine Souza Sandro J. de Debily Marie-Anne Devignes Marie-Dominique Dubchak Inna Endo Toshinori Estreicher Anne Eyras Eduardo Fukami-Kobayashi Kaoru R. Gopinath Gopal Graudens Esther Hahn Yoonsoo Han Michael Han Ze-Guang Hanada Kousuke Hanaoka Hideki Harada Erimi Hashimoto Katsuyuki Hinz Ursula Hirai Momoki Hishiki Teruyoshi Hopkinson Ian Imbeaud Sandrine Inoko Hidetoshi Kanapin Alexander Kaneko Yayoi Kasukawa Takeya Kelso Janet Kersey Paul Kikuno Reiko Kimura Kouichi Korn Bernhard Kuryshev Vladimir Makalowska Izabela Makino Takashi Mano Shuhei Mariage-Samson Regine Mashima Jun Matsuda Hideo Mewes Hans-Werner Minoshima Shinsei Nagai Keiichi Nagasaki Hideki Nagata Naoki Nigam Rajni Ogasawara Osamu Ohara Osamu Ohtsubo Masafumi Okada Norihiro Okido Toshihisa Oota Satoshi Ota Motonori Ota Toshio Otsuki Tetsuji Piatier-Tonneau Dominique Poustka Annemarie Ren Shuang-Xi Saitou Naruya Sakai Katsunaga Sakamoto Shigetaka Sakate Ryuichi Schupp Ingo Servant Florence Sherry Stephen Shiba Rie Shimizu Nobuyoshi Shimoyama Mary Simpson Andrew J. Soares Bento Steward Charles Suwa Makiko Suzuki Mami Takahashi Aiko Tamiya Gen Tanaka Hiroshi Taylor Todd Terwilliger Joseph D. Unneberg Per Veeramachaneni Vamsi Watanabe Shinya Wilming Laurens Yasuda Norikazu Yoo Hyang-Sook Stodolsky Marvin Makalowski Wojciech Go Mitiko Nakai Kenta Takagi Toshihisa Kanehisa Minoru Sakaki Yoshiyuki Quackenbush John Okazaki Yasushi Hayashizaki Yoshihide Hide Winston Chakraborty Ranajit Nishikawa Ken Sugawara Hideaki Tateno Yoshio Chen Zhu Oishi Michio Tonellato Peter Apweiler Rolf Okubo Kousaku Wagner Lukas Wiemann Stefan Strausberg Robert L. Isogai Takao Auffray Charles Nomura Nobuo Gojobori Takashi Sugano Sumio
出版者: Public Library of Science
雑誌: PLoS Biology (ISSN:15449173)
巻号頁・発行日: vol.2, no.6, pp.856-875, 2004-06
被引用文献数: 3 226

The human genome sequence defines our inherent biological potential; the realization of the biology encoded therein requires knowledge of the function of each gene. Currently, our knowledge in this area is still limited. Several lines of investigation have been used to elucidate the structure and function of the genes in the human genome. Even so, geneprediction remains a difficult task, as the varieties of transcripts of a gene may vary to a great extent. We thus performed an exhaustive integrative characterization of 41,118 full-length cDNAs that capture the gene transcripts as complete functional cassettes, providing an unequivocal report of structural and functional diversity at the gene level.Our international collaboration has validated 21,037 human gene candidates by analysis of high-quality full-length cDNA clones through curation using unified criteria. This led to the identification of 5,155 new gene candidates. It also manifested the most reliable way to control the quality of the cDNA clones. We have developed a human gene database, called the H-Invitational Database (H-InvDB; http://www.h-invitational.jp/). It provides the following:integrative annotation of human genes, description of gene structures, details of novel alternative splicing isoforms, non-protein-coding RNAs, functional domains, subcellular localizations, metabolic pathways, predictions of protein three-dimensional structure, mapping of known single nucleotide polymorphisms (SNPs), identification of polymorphic microsatellite repeats within human genes, and comparative results with mouse full-length cDNAs. The H-InvDB analysis has shown that up to 4% of the human genome sequence (National Center for Biotechnology Information build 34 assembly) may contain misassembled or missing regions. We found that 6.5% of the human gene candidates(1,377 loci) did not have a good protein-coding open reading frame, of which 296 loci are strong candidates for nonprotein-coding RNA genes. In addition, among 72,027 uniquely mapped SNPs and insertions/deletions localized within human genes, 13,215 nonsynonymous SNPs, 315 nonsense SNPs, and 452 indels occurred in coding regions. Together with 25 polymorphic microsatellite repeats present in coding regions, they may alter protein structure, causingphenotypic effects or resulting in disease. The H-InvDB platform represents a substantial contribution to resources needed for the exploration of human biology and pathology.

2018-06-13 06:30:13
5 CiteULike
1 + 0 Twitter

6 0 0 0 Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

著者: HAMILL OP.
雑誌: Pflugers Arch
巻号頁・発行日: vol.391, pp.85-100, 1981
被引用文献数: 191 13357

2014-06-14 21:46:42
5 CiteULike
1 + 0 Twitter

6 0 0 0 OA Genome Features of “Dark-Fly”, a Drosophila Line Reared Long-Term in a Dark Environment

著者: Izutsu Minako Zhou Jun Sugiyama Yuzo Nishimura Osamu Aizu Tomoyuki Toyoda Atsushi Fujiyama Asao Agata Kiyokazu Fuse Naoyuki
出版者: Public Library of Science
雑誌: PLoS ONE (ISSN:19326203)
巻号頁・発行日: vol.7, no.3, pp.e33288, 2012-03-14
被引用文献数: 28

「暗黒ショウジョウバエ」のゲノム解読-暗闇への適応のメカニズム. 京都大学プレスリリース. 2012-03-15.

2014-03-27 13:18:25
5 CiteULike
1 + 1 Twitter

7 0 0 0 Self-explanations : How students study and use examples in learning to solve problems

著者: CHI M. T. H.
雑誌: Cognitive Science
巻号頁・発行日: vol.13, pp.145-182, 1989
被引用文献数: 26 131

2012-08-18 19:18:43
4 CiteULike
3 + 0 Twitter

5 0 0 0 Dopamine-dependent plasticity of corticostriatal synapses

著者: REYNOLDS John N. J. WICKENS Jeffery R.
雑誌: Neural networks : the official journal of the International Neural Network Society (ISSN:08936080)
巻号頁・発行日: vol.15, no.4, pp.507-521, 2002-06-01
参考文献数: 116
被引用文献数: 10 376

2018-07-30 06:00:22
4 CiteULike
1 + 0 Twitter

5 0 0 0 Rubber hands 'feel' touch that eyes see

著者: BOTVINICK M
雑誌: Nature
巻号頁・発行日: vol.391, 1998
被引用文献数: 16 2898

2018-07-19 11:02:47
4 CiteULike
1 + 0 Twitter

5 0 0 0 IR The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts

著者: Yamasaki Chisato Murakami Katsuhiko Fujii Yasuyuki Sato Yoshiharu Harada Erimi Takeda Jun-ichi Taniya Takayuki Satake Ryuichi Kikugawa Shingo Shimada Makoto Tanino Motohiko Halligan Brian Shimoyama Mary Twigger Simon Yura Kei Kimura Kouichi Yasuda Tomohiro Nishikawa Tetsuo Akiyama Yutaka Motono Chie Mukai Yuri Shionyu Masafumi Nagasaki Hideki Suwa Makiko Horton Paul Kikuno Reiko Ohara Osamu Lancet Doron Eveno Eric Graudens Esther Imbeaud Sandrine Debily Marie Anne Jia Libin Hayashizaki Yoshihide Amid Clara Han Michael Osanger Andreas Endo Toshinori Thomas Michael A. Hirakawa Mika Makalowski Wojciech Nakao Mitsuteru Kim Nam-Soon Thierry-Mieg Danielle Yoo Hyang-Sook De Souza Sandro J. Bonaldo Maria de Fatima Niimura Yoshihito Kuryshev Vladimir Schupp Ingo Wiemann Stefan Bellgard Matthew Thierry-Mieg Jean Wagner Lukas Zhang Qinghua Go Mitiko Minoshima Shinsei Ohtsubo Masafumi Hanada Kousuke Koyanagi Kanako O. Tonellato Peter Isogai Takao Zhang Ji Lenhard Boris Kim Sangsoo Chen Zhu Hinz Ursula Estreicher Anne Nakai Kenta Makalowska Izabela Barrero Roberto A. Hide Winston Tiffin Nicola Wilming Laurens Chakraborty Ranajit Soares Marcelo Bento Chiusano Maria Luisa Suzuki Yutaka Auffray Charles Yamaguchi-Kabata Yumi Itoh Takeshi Gough Craig Hishiki Teruyoshi Fukuchi Satoshi Nishikawa Ken Sugano Sumio Nomura Nobuo Tateno Yoshio Imanishi Tadashi Gojobori Takashi Chun Hong-Woo Habara Takuya Hanaoka Hideki Hayakawa Yosuke Hilton Philip B. Kaneko Yayoi Kanno Masako Kawahara Yoshihiro Kawamura Toshiyuki Matsuya Akihiro Nagata Naoki Nishikata Kensaku Ogura Noda Akiko Nurimoto Shin Saichi Naomi Sakai Hiroaki Sanbonmatsu Ryoko Shiba Rie Suzuki Mami Takabayashi Kazuhiko Takahashi Aiko Tamura Takuro Tanaka Masayuki Tanaka Susumu Todokoro Fusano Yamaguchi Kaori Yamamoto Naoyuki Okido Toshihisa Mashima Jun Hashizume Aki Jin Lihua Lee Kyung-Bum Lin Yi-Chueh Nozaki Asami Sakai Katsunaga Tada Masahito Miyazaki Satoru Makino Takashi Ohyanagi Hajime Osato Naoki Tanaka Nobuhiko Suzuki Yoshiyuki Ikeo Kazuho Saitou Naruya Sugawara Hideaki O'Donovan Claire Kulikova Tamara Whitfield Eleanor
出版者: Oxford University Press
雑誌: Nucleic Acids Research (ISSN:03051048)
巻号頁・発行日: vol.36, no.1, pp.D793-D799, 2008-01
被引用文献数: 12

Here we report the new features and improvements in our latest release of the H-Invitational Database (H-InvDB; http://www.h-invitational.jp/), a comprehensive annotation resource for human genes and transcripts. H-InvDB, originally developed as an integrated database of the human transcriptome based on extensive annotation of large sets of full-length cDNA (FLcDNA) clones, now provides annotation for 120 558 human mRNAs extracted from the International Nucleotide Sequence Databases (INSD), in addition to 54 978 human FLcDNAs, in the latest release H-InvDB_4.6. We mapped those human transcripts onto the human genome sequences (NCBI build 36.1) and determined 34 699 human gene clusters, which could define 34 057 (98.1%) protein-coding and 642 (1.9%) non-protein-coding loci; 858 (2.5%) transcribed loci overlapped with predicted pseudogenes. For all these transcripts and genes, we provide comprehensive annotation including gene structures, gene functions, alternative splicing variants, functional non-protein-coding RNAs, functional domains, predicted sub cellular localizations, metabolic pathways, predictions of protein 3D structure, mapping of SNPs and microsatellite repeat motifs, co-localization with orphan diseases, gene expression profiles, orthologous genes, protein–protein interactions (PPI) and annotation for gene families. The current H-InvDB annotation resources consist of two main views: Transcript view and Locus view and eight sub-databases: the DiseaseInfo Viewer, H-ANGEL, the Clustering Viewer, G-integra, the TOPO Viewer, Evola, the PPI view and the Gene family/group.

2018-06-13 07:30:14
4 CiteULike
1 + 0 Twitter

5 0 0 0 OA Slow dynamics, dynamic heterogeneities, and fragility of supercooled liquids confined in random media

著者: Kim Kang Miyazaki Kunimasa Saito Shinji
出版者: IOP Publishing
雑誌: Journal of physics. Condensed matter (ISSN:09538984)
巻号頁・発行日: vol.23, no.23, pp.234123, 2011-05
被引用文献数: 39 26

Using molecular dynamics simulations, we study the slow dynamics of supercooled liquidsconfined in a random matrix of immobile obstacles. We study the dynamical crossover fromglass-like to Lorentz-gas-like behavior in terms of the density correlation function, the meansquare displacement, the nonlinear dynamic susceptibility, the non-Gaussian parameter, and thefragility. We find the cooperative and spatially heterogeneous dynamics to be suppressed as theobstacle density increases, leading to a more Arrhenius-like behavior in the temperaturedependence of the relaxation time. Our findings are qualitatively consistent with the results ofrecent experimental and numerical studies for various classes of spatially heterogeneoussystems. We also investigate the dependence of the dynamics of mobile particles on theprotocol used to generate the random matrix. A re-entrant transition from the arrested phase tothe liquid phase as the mobile particle density increases is observed for a class of protocols.This re-entrance is explained in terms of the distribution of the volume of the voids that areavailable to the mobile particles.

2013-01-31 08:31:56
4 CiteULike
1 + 0 Twitter

5 0 0 0 Human-Computer Interaction Using Eye-Gaze Input

著者: HUTCHINSON T. E.
雑誌: IEEE Trans. Systems, Man & Cybernetics
巻号頁・発行日: vol.19, pp.1527-1534, 1989
被引用文献数: 53 408

5 0 0 0 OA Neural coding of syntactic structure in learned vocalizations in the songbird.

著者: Fujimoto Hisataka Hasegawa Taku Watanabe Dai
出版者: The Society for Neuroscience
雑誌: The Journal of neuroscience : the official journal of the Society for Neuroscience (ISSN:02706474)
巻号頁・発行日: vol.31, no.27, pp.10023-10033, 2011-07-06
被引用文献数: 94

鳥類の音声における文法規則の神経コーディングの解明. 京都大学プレスリリース. 2011-7-15.

2012-02-25 19:54:55
4 CiteULike
1 + 0 Twitter

5 0 0 0 Multiple pathways in the decision to flower : enabling, promoting, and resetting

著者: BOSS P. K.
雑誌: Plant Cell
巻号頁・発行日: vol.16, pp.S18-S31, 2004
被引用文献数: 16 517

2011-06-16 23:30:10
4 CiteULike
1 + 0 Twitter

21 0 0 0 OA Out of Cite, Out of Mind: The Current State of Practice, Policy, and Technology for the Citation of Data

著者: CODATA-ICSTI Task Group on Data Citation Standards and Practices
出版者: CODATA
雑誌: Data Science Journal (ISSN:16831470)
巻号頁・発行日: pp.OSOM13-043, (Released:2013-09-08)
参考文献数: 185
被引用文献数: 56

The use of published digital data, like the use of digitally published literature, depends upon the ability to identify, authenticate, locate, access, and interpret them. Data citations provide necessary support for these functions, as well as other functions such as attribution of credit and establishment of provenance. References to data, however, present challenges not encountered in references to literature. For example, how can one specify a particular subset of data in the absence of familiar conventions such as page numbers or chapters? The traditions and good practices for maintaining the scholarly record by proper references to a work are well established and understood in regard to journal articles and other literature, but attributing credit by bibliographic references to data are not yet so broadly implemented. This report discusses the current state of data citation practices, its supporting infrastructure, challenges to implementation of good data citation practices, and open research questions.