- 著者
- Takahiro Kobayashi Hideki Kitahara Ken Kato Yuichi Saito Yoshio Kobayashi
- 出版者
- The Japanese Circulation Society
- 雑誌
- Circulation Journal (ISSN:13469843)
- 巻号頁・発行日
- pp.CJ-22-0202, (Released:2022-08-27)
- 参考文献数
- 30
- 被引用文献数
- 4
Background: Dialysis patients have strong intracoronary calcification, accelerated by secondary hyperparathyroidism as well as atherosclerosis. We evaluated the association of intact parathyroid hormone (iPTH) level with intracoronary calcification evaluated by intravascular ultrasound (IVUS), and its impact on both stent expansion after percutaneous coronary intervention (PCI) and long-term clinical outcomes, in dialysis patients with coronary artery disease (CAD).Methods and Results: A total of 116 patients on dialysis, who underwent PCI with IVUS guidance between March 2012 and December 2020, were enrolled. Patients were divided into 2 groups based on their median iPTH level. The degree of intracoronary calcification was evaluated by calcification score using grayscale IVUS in the target lesions. Preprocedural calcification scores were significantly higher in the high iPTH group compared with the low iPTH group (2.9±1.1 vs. 2.1±0.7, P<0.001). After PCI, the high iPTH group had a significantly lower stent expansion index (0.6±0.2 vs. 0.7±0.1, P<0.001) and stent symmetry index (0.5±0.1 vs. 0.7±0.1, P<0.001) compared with the low iPTH group. The incidence of major adverse cardiac or cerebrovascular events within 3 years was significantly higher in the high iPTH group (log-rank P<0.05).Conclusions: High iPTH level is likely to increase intracoronary calcification, and cause inadequate stent expansion, which may be associated with increased risk of future adverse events in dialysis patients with CAD requiring PCI.
- 著者
- 横地 清
- 出版者
- 一般社団法人 数学教育学会
- 雑誌
- 数学教育学会誌 (ISSN:13497332)
- 巻号頁・発行日
- vol.47, no.1-2, pp.91-95, 2006 (Released:2020-06-13)
3 0 0 0 OA いじめっ子・いじめられっ子 “いじめ”の構造と指導
- 著者
- 竹内 常一 横山 明 藤田 昌士 稲村 博 金 賛汀 斎藤 晴雄
- 出版者
- 一般社団法人 日本教育学会
- 雑誌
- 教育学研究 (ISSN:03873161)
- 巻号頁・発行日
- vol.53, no.1, pp.14-27, 1986-03-30 (Released:2009-01-13)
- 著者
- Suchada CHUANUWATANAKUL Orawon CHAILAPAKUL Shoji MOTOMIZU
- 出版者
- The Japan Society for Analytical Chemistry
- 雑誌
- Analytical Sciences (ISSN:09106340)
- 巻号頁・発行日
- vol.24, no.4, pp.493-498, 2008 (Released:2008-04-10)
- 参考文献数
- 40
- 被引用文献数
- 36 47
The electrochemical properties of chloramphenicol at a boron-doped diamond thin-film (BDD) electrode were studied using cyclic voltammetry. The highest current response of chloramphenicol was obtained with phosphate buffer, pH 6 (0.1 M) in 1% ethanol. The relationship between the concentration of chloramphenicol and the current response was linear over the range of 0.1 - 10 mM (R2 = 0.9990). The amount of chloramphenicol was analyzed by flow-injection analysis. A thin-layer flow cell equipped with a BDD electrode was used as an amperometric detector, and experiments were carried out at -0.7 V (vs. Ag/AgCl). The linear relationship between the current response and the concentration of chloramphenicol in the range of 0.1 - 50 µM (R2 = 0.9948) and the limit of detection of 0.03 µM (S/N = 3) were obtained. This method has been successfully applied to the determination of chloramphenicol in sterile eye drops and milk sample by the standard addition method. The average recoveries of chloramphenicol in eye drops were 98.0%, and the average recoveries of chloramphenicol from spiked milk were 93.9 - 103%.
3 0 0 0 OA 核保有の論理とその内外への影響
- 著者
- 伊藤 融
- 出版者
- 一般財団法人 アジア政経学会
- 雑誌
- アジア研究 (ISSN:00449237)
- 巻号頁・発行日
- vol.53, no.3, pp.43-56, 2007-07-31 (Released:2014-09-30)
- 参考文献数
- 35
In May 1998, India and Pakistan carried out a series of nuclear tests and declared themselves “nuclear powers” — a move that shocked the international community and added a newdimension to the rivalries between these two neighbors. This article will attempt to analyze what led both to this nuclearization and what kind of influence it had on the whole world as well as on the region.From a strategic viewpoint, India had pushed ahead with its nuclear program in order to counter the threat of China, not of Pakistan, whereas Pakistan’s program was aimed at reducing the threat posed by India. That is to say, the power imbalance in the region (China > India > Pakistan) encouraged these two countries to go nuclear. India and Pakistan have faced increased security-related concerns since the collapse of the alliance structure that built up during the Cold War. In addition to these security interests, rising nationalism in the midst of globalization has created a political trend that has encouraged nuclearization.Now, in retrospect, we can ask the question: which side has benefited most from nuclearization?Regionally, Pakistan seems to have seized more advantages militarily and diplomatically, especially regarding the Kashmir issue. Globally, however, nuclearization has helped India to rise in the world: most major powers, including the United States, cannot help regarding and treating India as a global player. In contrast, the international community regards Pakistan with suspicion in the wake of revelations about the “nuclear black market.”In fact, this nuclearization, which drew international concern about the risk of nuclear war, has not only contributed to sustaining the ongoing peace process since 2003, but has also created aninternational environment in which each side stops short of resorting to war even in times of crisis. “Rising India” will also hesitate to draw a sword. Unfortunately, however, it is difficult to conclude that a stable“ nuclear peace” has been established between India and Pakistan considering their geopolitical and strategic characteristics, lack of a relationship of mutual trust, persistent cross-border terrorism, and the fragile state foundations of Pakistan.
- 著者
- Chien-An Yao I-Ling Chen Chung-Yen Chen Pao-Ling Torng Ta-Chen Su
- 出版者
- Japan Atherosclerosis Society
- 雑誌
- Journal of Atherosclerosis and Thrombosis (ISSN:13403478)
- 巻号頁・発行日
- pp.63254, (Released:2022-04-20)
- 参考文献数
- 46
- 被引用文献数
- 1
Aim: This study aimed to determine whether sleep disturbance, defined as the wakeup frequency at night, is associated with atherogenic dyslipidemia and to explore possible sex differences. Methods: A total of 1,368 adults aged 19–70 years were included in the study of lifestyles and atherogenic dyslipidemia at the National Taiwan University Hospital in the period of 2008–2012. They completed a questionnaire regarding lifestyle information and sleep quality, including sleep hour duration, use of sleeping pills, and wakeup frequency during nighttime sleep. The measured lipid profiles included total cholesterol, triglycerides, low- and high-density lipoprotein cholesterol (LDL-C and HDL-C, respectively), non-HDL-C, and small dense LDL-C (sdLDL-C). Multivariate logistic regression was performed to determine habitual interrupted sleep and the odds ratio of atherogenic dyslipidemia following adjustment for conventional risk factors and for sex-based subgroup analysis. Results: A wakeup frequency ≥ 3 times per night was independently associated with an increased risk [odds ratio (95% confidence interval)] of dyslipidemia was 1.96 (1.17–3.28), and non-HDL-C ≥ 160 mg/dL was 1.78 (1.09–2.89). A higher wakeup frequency was associated with increased atherogenic dyslipidemia in women than in men. The multivariate adjusted relative risks for non-HDL ≥ 160 mg/dL and cholesterol ≥ 200 mg/dL were 3.05 (1.27–7.34) and 4.01(1.29-12.45) for female individuals with insomnia and those with a wakeup frequency ≥ 2 times per night, respectively. Conclusion: A higher wakeup frequency was associated with atherogenic dyslipidemia in Taiwanese adults, particularly in women. This study also provided another evidence of increasing cardiovascular diseases in subjects with habitual interrupted sleep.
3 0 0 0 OA 石狩湾の津波と副振動
- 著者
- 高橋 將
- 出版者
- 北海道大学
- 雑誌
- 北海道大學工學部研究報告 (ISSN:0385602X)
- 巻号頁・発行日
- vol.130, pp.17-32, 1986-03-25
3 0 0 0 OA 徳島の阿波踊り/阿波踊りの徳島
- 著者
- 立岡 裕士
- 出版者
- 金沢大学文学部地理学教室
- 雑誌
- 金沢大学文学部地理学報告 (ISSN:0289789X)
- 巻号頁・発行日
- vol.第10号, pp.87-100, 2002-03-15
3 0 0 0 OA 官報
- 著者
- 大蔵省印刷局 [編]
- 出版者
- 日本マイクロ写真
- 巻号頁・発行日
- vol.1919年07月21日, 1919-07-21
- 著者
- Flora Somidin Stuart David McDonald Xiaozhou Ye Dongdong Qu Keith Sweatman Tetsuya Akaiwa Tetsuro Nishimura Kazuhiro Nogita
- 出版者
- The Japan Institute of Electronics Packaging
- 雑誌
- Transactions of The Japan Institute of Electronics Packaging (ISSN:18833365)
- 巻号頁・発行日
- vol.13, pp.E19-004-1-E19-004-11, 2020 (Released:2020-05-27)
- 参考文献数
- 29
- 被引用文献数
- 4
The polymorphic transformation that occurs in the Cu6Sn5 intermetallic compound (IMC) at 186°C has the potential to generate stresses that could lead to cracking of that phase in soldered joints during the multiple reflow cycles of a typical printed board assembly process and the thermal cycles to which electronic assemblies are exposed during service. In this paper the authors report on the effect of variations in the cooling stage of a reflow soldering thermal profile on the incidence and extent of cracking in the Cu6Sn5 at the interface between solder alloys and copper substrates. The solder alloy/substrate combinations studied were Sn-3.0Ag-0.5Cu/Cu and Sn-0.7Cu-0.05Ni-1.5Bi/Cu. The cooling conditions were (i) the direct-cooling of a conventional reflow profile, and (ii) an alternative reflow profile with one of three extended isothermal holding periods of 30, 60, and 180 seconds at 140°C during the cooling stage. It was found that the alternative reflow profiles reduced cracking in the interfacial Cu6Sn5 IMC layer and this resulted in improved resistance of the reflowed solder ball to failure in high speed impact shear when the distribution of stress tends to favor crack propagation though the interfacial IMC rather than through the bulk solder.