著者
遠藤 興一
出版者
明治学院大学
雑誌
明治学院論叢 (ISSN:09189858)
巻号頁・発行日
no.235, pp.p71-108, 1976-01
著者
遠藤 興一
出版者
明治学院大学
雑誌
明治学院論叢 (ISSN:09189858)
巻号頁・発行日
no.231, pp.p85-128, 1975-09
著者
遠藤 興一
出版者
明治学院大学
雑誌
明治学院論叢 (ISSN:09189858)
巻号頁・発行日
no.527, pp.p1-24, 1993-10
著者
大塚 雄司 原澤 信介 杉浦 仁 小池 美由紀 秋元 秀郎 石井 利明 阿部田 ひろみ 岡部 龍也 久代 登志男 上松瀬 勝男
出版者
Japanese Society of Nephrology
雑誌
日本腎臓学会誌 (ISSN:03852385)
巻号頁・発行日
vol.42, no.8, pp.619-624, 2000

Previous studies have shown that hypertension causes endothelial dysfunction. To study the influence of exogenous nitric oxide (NO) on endothelial dysfunction produced by hypertension, we administered a non-depressor dose of nipradilol to two-kidney, one clip renovascular hypertensive rats (2K1C). Sprague-Dawley rats underwent either sham surgery (G-l) or clipping of the left renal artery. From day seven, 2K1C were randomized into 3 groups, placebo treatment (G-2), nipradilol treament (G-3, ) and propranolol treatment (G-4). Urinary NO<SUP>-</SUP><SUB>2</SUB> +N0<SUP>-</SUP><SUB>3</SUB> (NOx) excretion (UNOxV) was measured 4 weeks after clipping, and then, acetylcholine (Ach), A23187, or sodium nitroprusside (SNP) -induced relaxation were measured in the aorta. Blood pressure was increased in G-2, G-3, and G-4 compared to G-1. UNOxV was lower in G-2, G-3, and G-4 compared to G-1, but UNOxV was higher in G-3 compared to G-2 and G-4. Although Ach or A23187-induced relaxation was significantly decreased in isolated artery from G-2, G-3, and G-4 compared with those from G-1. Ach- or A23187-induced relaxation was improved in G-3. SNP induced relaxation did not differ among the 4 groups. These results suggest that exogenous NO from nipradilol reduces the endothelial dysfunction caused by hypertension without changing the blood pressure.
著者
細谷 聡 宮地 力 岡田 守彦
出版者
一般社団法人日本機械学会
雑誌
日本機械学會論文集. C編 (ISSN:03875024)
巻号頁・発行日
vol.64, no.623, pp.2411-2416, 1998-07-25

The purpose of this study was to clarify the influence of different strings on the dynamics of Japanese Bow, and to investigate the relationship between the measured mechanical data and the feeling of shooter. Four strings, aramid fiber "Kevlar", "Technora", polyester fiber "Vectran", and hemp string were used for the shooting experiment by nine subjects. At that time, feeling data through questionnaires were collected. The results were summarized as follows: (1) in the logarithmic decrement of bending and torsional oscillation after release, hemp string was highest in this four strings, (2) the difference of fibers didn't have influence on frequency of the oscillation, (3) in the energy transmission efficiency, Kevlar, Technora and Vectran were about 69%, hemp was 67.7%, (4) it is also found that the feeling of shooter was related to the measured mechanical data significantly.