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Previous studies have shown that hypertension causes endothelial dysfunction. To study the influence of exogenous nitric oxide (NO) on endothelial dysfunction produced by hypertension, we administered a non-depressor dose of nipradilol to two-kidney, one clip renovascular hypertensive rats (2K1C). Sprague-Dawley rats underwent either sham surgery (G-l) or clipping of the left renal artery. From day seven, 2K1C were randomized into 3 groups, placebo treatment (G-2), nipradilol treament (G-3, ) and propranolol treatment (G-4). Urinary NO-2 +N0-3 (NOx) excretion (UNOxV) was measured 4 weeks after clipping, and then, acetylcholine (Ach), A23187, or sodium nitroprusside (SNP) -induced relaxation were measured in the aorta. Blood pressure was increased in G-2, G-3, and G-4 compared to G-1. UNOxV was lower in G-2, G-3, and G-4 compared to G-1, but UNOxV was higher in G-3 compared to G-2 and G-4. Although Ach or A23187-induced relaxation was significantly decreased in isolated artery from G-2, G-3, and G-4 compared with those from G-1. Ach- or A23187-induced relaxation was improved in G-3. SNP induced relaxation did not differ among the 4 groups. These results suggest that exogenous NO from nipradilol reduces the endothelial dysfunction caused by hypertension without changing the blood pressure.

2016-11-30 04:15:12
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1 0 0 0 2A1-H1 3.11後の「科学教育と科学論」再考 : 福島訪問から科学教育の社会的責任論へ(ポスト3.11の科学教育を科学論の視点より考える,課題研究,学びの原点への回帰-学習の質を高める科学教育研究-)

著者: 北田薫
出版者: 一般社団法人日本科学教育学会
雑誌: 年会論文集
巻号頁・発行日: vol.37, pp.34-35, 2013-09-06

2016-11-30 04:00:12
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https://ci.nii.ac.jp/naid/110009903870

1 0 0 0 「女性の人権」への基礎視角 : 川島武宜氏と渡辺洋三氏の家族論をめぐって(長谷川正安教授退官記念論文集 : 転機にたつ憲法と憲法学)

著者: 若尾典子
出版者: 名古屋大学
雑誌: 名古屋大學法政論集 (ISSN:04395905)
巻号頁・発行日: vol.109, pp.267-286, 1986-03-20

2016-11-30 03:53:21
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https://ci.nii.ac.jp/naid/110000295999

1 0 0 0 憲法24条と憲法「改正」・教育基本法「改正」 (特集=現代家族をめぐる法状況--個人の尊厳と両性の平等をめぐって)

著者: 植野妙実子
出版者: 日本評論社
雑誌: 法律時報 (ISSN:03873420)
巻号頁・発行日: vol.78, no.11, pp.13-18, 2006-10

2016-11-30 03:52:44
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https://ci.nii.ac.jp/naid/40007477503

1 0 0 0 民科法律部会憲法問題特別委員会(8)現代改憲論における家族条項改変問題

著者: 中里見博
出版者: 日本評論社
雑誌: 法律時報 (ISSN:03873420)
巻号頁・発行日: vol.77, no.9, pp.84-89, 2005-08

2016-11-30 03:52:15
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https://ci.nii.ac.jp/naid/40006858907

1 0 0 0 家族が担う「公」と「私」--親密圏への法的介入 (コロキウム=親密圏と公共圏--ジェンダー視点から見た民主主義法学の課題)

著者: 中里見博
出版者: 日本評論社
雑誌: 法の科学 (ISSN:03856267)
巻号頁・発行日: no.37, pp.117-128, 2006

2016-11-30 03:51:43
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https://ci.nii.ac.jp/naid/40015327595

1 0 0 0 和弓の弦の素材の違いが発射現象に及ぼす影響 (<小特集>スポーツ工学)

著者: 細谷聡宮地力岡田守彦
出版者: 一般社団法人日本機械学会
雑誌: 日本機械学會論文集. C編 (ISSN:03875024)
巻号頁・発行日: vol.64, no.623, pp.2411-2416, 1998-07-25

The purpose of this study was to clarify the influence of different strings on the dynamics of Japanese Bow, and to investigate the relationship between the measured mechanical data and the feeling of shooter. Four strings, aramid fiber "Kevlar", "Technora", polyester fiber "Vectran", and hemp string were used for the shooting experiment by nine subjects. At that time, feeling data through questionnaires were collected. The results were summarized as follows: (1) in the logarithmic decrement of bending and torsional oscillation after release, hemp string was highest in this four strings, (2) the difference of fibers didn't have influence on frequency of the oscillation, (3) in the energy transmission efficiency, Kevlar, Technora and Vectran were about 69%, hemp was 67.7%, (4) it is also found that the feeling of shooter was related to the measured mechanical data significantly.