- 基礎心理学研究 (ISSN:02877651)
- vol.38, no.1, pp.137-142, 2019-09-30 (Released:2019-12-10)
Kaolin clay intake is generated in rats by a variety of nausea-inducing treatments, including rotation (motion sickness), irradiation, and administration of emetic chemicals such as lithium chloride, copper sulfate, ritonavir, recreational drugs (e.g., morphine, apomorphine, nicotine, and ethanol), and various anti-cancer drugs (e.g., cisplatin, cyclophosphamide, and 5-fluorouracil). Recent studies conducted in my laboratory have shown that kaolin clay intake is also generated in rats by running in an activity wheel or swimming in a water bucket, suggesting that these activities induce visceral discomfort similar to nausea. This finding is consonant with the fact that, similar to emetic treatments conventionally employed in conditioned taste-aversion studies in rats, running and swimming act as unconditioned stimuli to establish avoidance of a paired taste.