著者
Kazunori HORIBE Ken-Ichi TAHARA
出版者
The Mathematical Society of Japan
雑誌
Japanese journal of mathematics. New series (ISSN:02892316)
巻号頁・発行日
vol.10, no.1, pp.137-157, 1984 (Released:2008-12-16)
参考文献数
9
被引用文献数
6

We list the stable structure of these six groups below.(1) G1=Zp׋x, y, z|xp=yp=zp=[x, z]=[y, z]=1, [x, y]=z›, n0=3p-2, π=2 Q3p-2(G1)=Zp(1/2)(p+1)(p2+p+1), Q3p-1(G1)=Zp(1/2)(p+1)(p2+p+1)+1(2) G2=‹u, x, y|up=xp=yp2=[u, y]=[x, y]=1, [u, x]=yp›, n0=3p-2, π=1, Q3p-2(G2)=Zp(2p2+p+1).(3) G3=Zp׋x, y|xp=yp2=1, [x, y]=yp›, n0=3p-2, π=1, Q3p-2(G3)=Zp(2p2+p+1).(4) G4=Zp(2)×Zp2 n0=3p-2, π=1, Q3p-2(G4)=Zp2×Zp(2p2+p-1).(5) G5=‹u, x, y|up=xp=yp2=[u, x]=[u, yp]=1, [u, y]=x, [x, y]=yp›, n0=4p-3, π=2, Q4p-3(G5)=Zp(1/2)(3p2+1)+p, Q4p-2(G5)=Zp(3/2)(p2+1)+p(6) G6=‹u, x, y|up=xp=yp2=[u, x]=[x, y]=1, [u, y]=x›, n0=4p-3, π=2, Q4p-3(G6)=Zp2×Zp(3/2)(p2-1)+p, Q4p-2(G6)=Zp2×Zp(1/2)(3p2-1)+p.
著者
Shion WATANABE Anna KOIKE Rui KANO Masahiko NAGATA Charles CHEN Cheol-Yong HWANG Atsuhiko HASEGAWA Hiroshi KAMATA
出版者
公益社団法人 日本獣医学会
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
pp.13-0433, (Released:2013-12-13)
被引用文献数
3 29

Topical or oral azole antifungals are commonly used in canine atopic dermatitis (AD) as the lipophilic yeast Malassezia pachydermatis exacerbates canine AD. To examine whether canine AD lesions harbor azole-resistant M. pachydermatis isolates in East Asia, we investigated the in vitro susceptibility of M. pachydermatis isolates to ketoconazole (KTZ) and itraconazole (ITZ) obtained from AD lesions of canines in Japan, Korea and Taiwan. The minimum inhibitory concentrations (MICs) of KTZ and ITZ were measured by the E-test using Sabouraud’s dextrose agar with 0.5% Tween 40. The MICs of KTZ and ITZ for isolates from canines with AD were significantly higher from the MICs for isolates from healthy canines. Our findings suggested that the clinical isolates from canine AD skin lesions were less susceptible to azoles than those from normal canine skin in East Asia.
著者
Yuriko Oi-KANO Teruo KAWADA Tatsuo WATANABE Fumihiro KOYAMA Kenichi WATANABE Reijirou SENBONGI Kazuo IWAI
出版者
Center for Academic Publications Japan
雑誌
Journal of Nutritional Science and Vitaminology (ISSN:03014800)
巻号頁・発行日
vol.54, no.5, pp.363-370, 2008 (Released:2008-11-11)
参考文献数
37
被引用文献数
23 51

The effects of oleuropein, a phenolic compound in extra virgin olive oil (EV-olive oil), on triglyceride metabolism were investigated by measuring the degree of thermogenesis in interscapular brown adipose tissue (IBAT), and noradrenaline and adrenaline secretions in rats. In Experiment 1, rats were given a high-fat diet (control diet) with the oleuropein supplementation of 1, 2 or 4 mg/kg of diet (0.1, 0.2 or 0.4% oleuropein diet, respectively). After 28 d of feeding, body weight, perirenal adipose tissue, epididymal fat pad, and plasma triglyceride, free fatty acid and total cholesterol concentrations were reduced by the 0.1, 0.2 or 0.4% oleuropein diet and were significantly lowest in rats fed the 0.4% oleuropein diet, as compared with those of rats fed with the control diet. The content of uncoupling protein 1 (UCP1) in IBAT and urinary noradrenaline and adrenaline excretions were significantly higher in rats fed the 0.1 or 0.2% oleuropein diet, as compared with those of rats fed with the control diet, although there were no significant differences in rats fed the 0.4% oleuropein diet. In Experiment 2, the effects of oleuropein on noradrenaline and adrenaline secretion were evaluated. The intravenous administration of oleuropein and oleuropein aglycone significantly increased plasma noradrenaline and adrenaline concentrations. Furthermore, oleuropein aglycone induced the secretions of noradrenaline and adrenaline about ten fold more potently than oleuropein. These results suggest that the phenolic compound oleuropein in EV-olive oil enhances thermogenesis by increasing the UCP1 content in IBAT and noradrenaline and adrenaline secretions in rats.
著者
中村 卓司 阿保 真 江尻 省 SHE Chiao-Yao YUE Jia 原 貴洋
出版者
国立極地研究所
雑誌
挑戦的萌芽研究
巻号頁・発行日
2010

高度100km付近には、ナトリウム原子、鉄原子など様々な金属が原子状態で存在する金属原子層がある。本研究では、この層に地上からレーザー光を照射して、遠隔地との通信を行うと同時にこの付近の高度の大気の様子を調べる大気観測を行うことのできるシステムについて、首都大学東京と国立極地研究所の5.3km離れたキャンパス同士で送受信実験を行い、また観測法/通信法を詳細に検討を行って、実現可能であることを示した。
著者
Yu-Ling SUN Chon-Ho YEN Ching-Fu TU
出版者
公益社団法人 日本獣医学会
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
pp.13-0448, (Released:2013-12-12)
被引用文献数
2 21

Loop-mediated isothermal amplification (LAMP) combined with enzyme-linked immunosorbent assay (LAMP–ELISA) and with lateral flow dipstick (LAMP–LFD) are rapid, sensitive and specific methods for the visual detection of clinical pathogens. In this study, LAMP–ELISA and LAMP–LFD were developed for the visual detection of canine parvovirus (CPV). For LAMP, a set of four primers (biotin-labeled forward inner primers) was designed to specifically amplify a region of the VP2 gene of CPV. The optimum time and temperature for LAMP were 60 min and 65°C, respectively. The specific capture oligonucleotide probes, biotin-labeled CPV probe for LAMP–ELISA and fluorescein isothiocyanate-labeled CPV probe for LAMP–LFD were also designed for hybridization with LAMP amplicons on streptavidin-coated wells and LFD strips, respectively. For the comparison of detection sensitivity, conventional PCR and LAMP for CPV detection were also performed. The CPV detection limits by PCR, PCR–ELISA, LAMP, LAMP–ELISA, and LAMP–LFD were 102, 102, 10−1, 10−1 and 10−1 TCID50/ml, respectively. In tests using artificially contaminated dog fecal samples, the samples with CPV inoculation levels of ≥1 TCID50/ml gave positive results by both LAMP–ELISA and LAMP–LFD. Our data indicated that both LAMP–ELISA and LAMP–LFD are promising as rapid, sensitive and specific methods for an efficient diagnosis of CPV infection.
著者
Md. Mottaleb HOSSAIN Md. Abdullah-AL HUMAYUN Md. Tanvir HASAN Ashraful Ghani BHUIYAN Akihiro HASHIMOTO Akio YAMAMOTO
出版者
一般社団法人 電子情報通信学会
雑誌
IEICE Transactions on Electronics (ISSN:09168524)
巻号頁・発行日
vol.E95.C, no.2, pp.255-261, 2012-02-01 (Released:2012-02-01)
参考文献数
26
被引用文献数
2 9

This paper reports on a theoretical study and modeling of a 1.55µm quantum dot heterostructure laser using InN as a promising candidate for the first time. Details of design and theoretical analysis of probability distribution of the optical transition energy, threshold current density, modal gain, and differential quantum efficiency are presented considering a single layer of quantum dots. Dependence of threshold current density on the RMS value of quantum dot size fluctuations and the cavity length is studied. A low threshold current density of ∼51Acm-2 is achieved at room temperature for a cavity length of 640µm. An external differential efficiency of ∼65% and a modal gain of ∼12.5cm-1 are obtained for the proposed structure. The results indicate that the InN based quantum dot laser is a promising one for the optical communication system.
著者
Korzekwa Anna J. 奥田 潔 Woclawek-Potocka Izabela 村上 周子 SKARZYNSKI Dariusz J
出版者
THE SOCIETY FOR REPRODUCTION AND DEVELOPMENT
雑誌
The Journal of reproduction and development (ISSN:09168818)
巻号頁・発行日
vol.52, no.3, pp.353-361, 2006-06-01
被引用文献数
9 54

We previously showed in <i>in vivo</i> and <i>in vitro</i> studies that nitric oxide (NO) is engaged in luteolysis in cattle. Nitric oxide produced locally in the bovine corpus luteum (CL) inhibits progesterone (P4) synthesis and is suggested to be a component of the luteolytic cascade induced by uterine prostaglandin (PG) F<sub>2</sub><sub>α</sub>. In the present study, the molecular mechanisms of NO action during structural luteolysis were studied in cultured bovine luteal cells (Days 15-17 of the estrous cycle). The effects of the NO donor (NONOate; 10<sup>-4</sup>M) on DNA fragmentation, cell viability, P4 production and caspase-3 activity were compared with those of PGF<sub>2</sub><sub>α</sub> (10<sup>-6</sup>M). Moreover, mobilization of intracellular calcium [Ca<sup>2+</sup>]<sub>i</sub> and gene expressions of Fas-L, Fas, bcl-2, bax, and caspase-3 in the cells were determined by semi-quantitative RT-PCR after NONOate treatment. Caspase-3 activity was examined calorimetrically. Contrary to PGF<sub>2</sub><sub>α</sub> NONOate decreased cell viability. DNA fragmentation after NONOate treatment increased by more than with PGF2<sub>2</sub><sub>α</sub>. NONOate increased mobilization of [Ca<sup>2+</sup>]<sub>i</sub> in the cells. Although the NO donor did not affect Fas-L and bcl-2 gene expression, it stimulated Fas and bax mRNA and caspase-3 expression. The ratio of bcl-2 to bax mRNA level decreased in the cells treated with NONOate. Moreover, NONOate stimulated caspase-3 activity more effectively than PGF<sub>2</sub><sub>α</sub>. The overall results suggest that NO is a luteolytic factor that plays a crucial role in regulation of the estrous cycle in structural luteolysis by inducing apoptosis of luteal cells in cattle.<br>
著者
Ozlem OZSOY-SACAN Omür KARABULUT-BULAN Sehnaz BOLKENT Refiye YANARDAG Yasemin OZGEY
出版者
(社)日本農芸化学会
雑誌
Bioscience, Biotechnology, and Biochemistry (ISSN:09168451)
巻号頁・発行日
vol.68, no.8, pp.1640-1648, 2004 (Released:2004-08-23)
参考文献数
51
被引用文献数
30

Chard (Beta vulgaris L. var cicla) is one of the medicinal herbs used by diabetics in Turkey. It has been reported to reduce blood glucose. We have investigated the effect of chard extracts on the liver by biochemical and morphological investigation. The plant extract was administered by the gavage technique to rats at a dose of 2 g/kg every d for 28 d, 14 d after experimental animals were made diabetic. In the diabetic group, some degenerative changes were observed by light and electron microscope examination, but degenerative changes decreased or were not observed in the diabetic group given chard. In the diabetic group, blood glucose levels, serum alanine, aspartate transaminase, alkaline phosphatase activities, total lipids, sialic and uric acid levels, liver lipid peroxidation (LPO), and nonenzymatic glycosylation (NEG) levels increased, while blood glutathione, body weight, and liver glutathione (GSH) levels decreased. The diabetic group given chard, serum alanine, aspartate transaminase, alkaline phosphatase activities, total lipid level, sialic and uric acid levels, blood glucose levels, and liver LPO and NEG levels decreased, but the other values increased. As a result of all the morphological and biochemical findings obtained, it was concluded that the extract of this plant has a protective effect on the liver in diabetes mellitus.

1 0 0 0 OA Cold Adaptations

著者
Jean-Claude LAUNAY Gustave SAVOUREY
出版者
独立行政法人 労働安全衛生総合研究所
雑誌
Industrial Health (ISSN:00198366)
巻号頁・発行日
vol.47, no.3, pp.221-227, 2009 (Released:2009-06-16)
参考文献数
79
被引用文献数
11 46

Nowdays, occupational and recreational activities in cold environments are common. Exposure to cold induces thermoregulatory responses like changes of behaviour and physiological adjustments to maintain thermal balance either by increasing metabolic heat production by shivering and/or by decreasing heat losses consecutive to peripheral cutaneous vasoconstriction. Those physiological responses present a great variability among individuals and depend mainly on biometrical characteristics, age, and general cold adaptation. During severe cold exposure, medical disorders may occur such as accidental hypothermia and/or freezing or non-freezing cold injuries. General cold adaptations have been qualitatively classified by Hammel and quantitatively by Savourey. This last classification takes into account the quantitative changes of the main cold reactions: higher or lower metabolic heat production, higher or lesser heat losses and finally the level of the core temperature observed at the end of a standardized exposure to cold. General cold adaptations observed previously in natives could also be developed in laboratory conditions by continuous or intermittent cold exposures. Beside general cold adaptation, local cold adaptation exists and is characterized by a lesser decrease of skin temperature, a more pronounced cold induced vasodilation, less pain and a higher manual dexterity. Adaptations to cold may reduce the occurrence of accidents and improve human performance as surviving in the cold. The present review describes both general and local cold adaptations in humans and how they are of interest for cold workers.
著者
Oyun-Erdene Zorigtkhuu
巻号頁・発行日
2013

Thesis (Ph. D. in Science)--University of Tsukuba, (A), no. 6483, 2013.3.25
著者
Eun-Joo Shin Wan Kyunn Whang Sungun Kim Jae-Hyung Bach Jin-Man Kim Xuan-Khanh Thi Nguyen Thuy-Ty Lan Nguyen Bae Dong Jung Kiyofumi Yamada Toshitaka Nabeshima Hyoung-Chun Kim
出版者
(公社)日本薬理学会
雑誌
Journal of Pharmacological Sciences (ISSN:13478613)
巻号頁・発行日
vol.113, no.4, pp.404-408, 2010 (Released:2010-08-18)
参考文献数
15
被引用文献数
11 25

Parishin C, a major component of Gastrodia elata BLUME (GE), was purified from GE. Because GE modulates the serotonergic system and the 5-HT1A receptor is an important therapeutic target of schizophrenia, we examined whether parishin C affects phencyclidine-induced abnormal behaviors in mice. Phencyclidine-induced abnormal behaviors were significantly ameliorated by parishin C. These effects were reversed by WAY 100635, a 5HT1A–receptor antagonist. Consistently, parishin C showed high affinity at 5-HT1A receptor as well as a 5-HT1A–agonist activity in a 8-OH-DPAT–stimulated [35S]GTP-γS binding assay. Our results suggest that the antipsychotic effects of parishin C require activation of 5-HT1A receptors.
著者
-
出版者
日本郵船株式会社
巻号頁・発行日
1930-07

1冊(表紙カラー冊子); (折りたたみ22.3×19cm) , 昭和5年7月 1 vol. [22.3×19cm] , 1930.7 日本政府は、南洋群島と内地、外地を結ぶ航路を日本郵船に請け負わせた。西回り線、東回り線、東西連絡線、サイパン線の 4線があり、1934年当時、西回り線とサイパン線は年に17便、それ以外の線は6便であった。なお、群島間の航路は、南洋貿易が請け負った。筑後丸(サイパン線)、山城丸(西回り線)など3千トン級の船舶が使用され、本資料には客室内部の珍しい写真も載せられている。
著者
Masafumi AKISAKA Liu ASATO Yin-Ching CHAN Makoto SUZUKI Tatsu UEZATO Shigeru YAMAMOTO
出版者
Center for Academic Publications Japan
雑誌
Journal of Nutritional Science and Vitaminology (ISSN:03014800)
巻号頁・発行日
vol.42, no.3, pp.241-248, 1996 (Released:2009-04-28)
参考文献数
14
被引用文献数
12 20

Energy and nutrient requirements of younger people have been well studied, unlike that of centenarians. The average life span of the Japanese is the longest in the world, and the population of the very aged is rapidly growing. In addition, the average life span of Okinawan people is the longest in all of Japan. Their food habits also differ from other parts of Japan. To obtain basic dietary information, we surveyed 21 centenarians in Okinawa (17 women and 4 men). The dietary survey was done by one 24h recall method, as was done for centenarians living throughout Japan (3). The energy intake of the Okinawan centenarians living at home was about 1, 100 kcal/day for both sexes, which was similar to that of centenarians throughout Japan. Energy, some nutrient intakes and food consumption pattern (in terms of food groups) were different from those of the centenarians throughout Japan. We also measured their heights, weights, hematological values and activities of daily living (ADL). Comparison between the nutrient intakes and the recommended dietary allowances (RDAs) estimated for the centenarians showed that the estimated RDA of energy for the Okinawan centenarians might be less than their actual intakes.