著者

Y. N.

出版者

Japan Society for Bioscience, Biotechnology, and Agrochemistry

雑誌

日本農芸化学会誌 (ISSN:00021407)

巻号頁・発行日

vol.53, no.3, pp.N27-N29, 1979

著者

T. Nakajima T. Morita Y. Sato

出版者

日本加圧トレーニング学会

雑誌

International Journal of KAATSU Training Research (ISSN:13494562)

巻号頁・発行日

vol.7, no.1, pp.1-6, 2011 (Released:2012-03-28)

参考文献数

7

被引用文献数

3 21

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KAATSU training is a novel training method conducted under special conditions of restricted muscle blood flow of the limbs with a specially-designed KAATSU belt. In 2006, we conducted a questionnaire survey across the whole of Japan to investigate the status of KAATSU training. After that, we have performed KAATSU training mainly for patients with cardiovascular diseases at a total of approximately 700 people per year, and no serious side effects of note have been found. However, it has also been applied for various purposes such as to increase the muscle strength and prevent the muscular atrophy of all kinds of patients including older people. And, in near future, it may be used to train more seriously affected patients with cachexia or sarcopenia. Therefore, in this review, we introduce the main matters reported over the five years since the questionnaire survey was conducted. In addition, we outline key considerations concerning the implementation of KAATSU training centered mainly on our previous experience and reports reached to us.

著者

Kiang Nancy Y.

出版者

日経サイエンス

雑誌

日経サイエンス (ISSN:0917009X)

巻号頁・発行日

vol.38, no.8, pp.64-73, 2008-07

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地球外生命を探す試みは,もはやSFやUFOハンターの世界にとどまらない。宇宙人の到来を待つのではなく,私たちのほうが彼らを探す時代になった。

著者

今井 章 Y. ロセッティ P. レヴォル

出版者

信州大学人文学部

雑誌

信州大学人文科学論集

巻号頁・発行日

vol.4, pp.85-91, 2017-03-15

著者

Barak Zafrir Ayman Jubran Gil Lavie David A. Halon Moshe Y. Flugelman Chen Shapira

出版者

日本循環器学会

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

pp.CJ-17-0392, (Released:2017-07-12)

参考文献数

26

被引用文献数

8

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Background:Familial hypercholesterolemia (FH) is associated with premature atherosclerotic cardiovascular disease (ASCVD). The introduction of potent therapeutic agents underlies the importance of improving clinical diagnosis and treatment gaps in FH.Methods and Results:A regional database of 1,690 adult patients with high-probability FH based on age-dependent peak-low-density lipoprotein cholesterol (LDL-C) cut-offs and exclusion of secondary causes of severe hypercholesterolemia, was examined to explore the clinical manifestations and current needs in the management of ASCVD, which was present in 248 patients (15%), of whom 83% had coronary artery disease (CAD); 19%, stroke; and 13%, peripheral artery disease. ASCVD was associated with male gender, higher peak LDL-C, lower high-density lipoprotein cholesterol (HDL-C), and traditional risk factor burden. Despite high-intensity statin (prescribed in 83% and combined with ezetimibe in 42%), attainment of LDL-C treatment goals was low, and associated with treatment intensity and drug adherence. Multivessel CAD (adjusted hazard ratios (HR), 3.05; 95% CI: 1.65–5.64), myocardial infarction, and the presence of ≥1 traditional risk factor (HR, 2.59; 95% CI: 1.42–4.71), were associated with repeat coronary revascularizations, in contrast with peak LDL-C >300 mg/dL (HR, 1.13; 95% CI: 0.66–1.91).Conclusions:Main manifestations of ASCVD in FH patients were premature, multivessel CAD with need for recurrent revascularization, associated with classical cardiovascular risk factors but not with peak LDL-C. In spite of intensive therapy with lipid-lowering agents, treatment gaps were significant, with low attainment of LDL-C treatment goals.

著者

Seuster R. Abe K. Aihara H. Asano Y. Aushev T. Bakich A. M. Barbero M. Bedny I. Bitenc U. Bizjak I. Bozek A. Dragic J. Drutskoy A. Eidelman S. Fang F. Gershon T. Go A. Gokhroo G. Golob B. Gorišek A. Hayasaka K. Kim H. J. Hazumi M. Hoshi Y. Hou S. Hou W. -S. Iijima T. Ikado K. Itoh R. Iwasaki Y. Kang J. H. Kang J. S. Kim S. M. Kapusta P. Katayama N. Kawai H. Kawasaki T. Khan H. R. Kichimi H. Križan P. Krokovny P. Kulasiri R. Kuo C. C. Kuzmin A. Kwon Y. -J. Lange J. S. Lesiak T. Okuno S. Li J. Lin S. -W. Mandl F. Mitaroff W. Miyake H. Miyazaki Y. Mizuk R. Nagamine T. Nagasaka Y. Nakano E. Olsen S. L. Nakao M. Nishida S. Nitoh O. Ogawa S. Ohshima T. Okabe T. Onuki Y. Ozaki H. Pakhlov P. Palka H. Park C. W. Park H. Park K. S. Pestotnik R. Takasaki F. Piilonen L. E. Sakai Y. Sato N. Schietinger T. Schneider O. Schümann J. Schwanda C. Sevior M. E. Shibuya H. Sidorov V. Tamai K. Somov A. Soni N. Stamen R. Stanič S. Starič M. Suzuki S. Y. Tamura N. Tanaka M. Taylor G. N. Teramoto Y. Tian X. C. Uehara S. Uglov T. Ueno K. Bračko M. Uno S. Urquijo P. Varner G. Wang C. C. Wang C. H. Wang M. -Z. Xie Q. L. Yabsley B. D. Yamaguchi A. Yamashita Y. Brodzicka J. Yamauchi M. Ying J. Yusa Y. Zhang L. M. Zhang Z. P. Zhilich V. Chen A. Cheon B. G. Choi Y. Chuvikov A. Cole S. Dalseno J. Danilov M. Dash M. Dong L. Y.

出版者

The American Physical Society

雑誌

PHYSICAL REVIEW D (ISSN:15507998)

巻号頁・発行日

vol.73, no.32002, pp.1-22, 2006

被引用文献数

70

著者

山本 亞実 大城 未緒 南 由歩 竹谷 怜子 小野 久江 A. Yamamoto M. Oshiro Y. Minami R. Taketani H. Ono

出版者

関西学院大学心理科学研究室

雑誌

関西学院大学心理科学研究 = Kwansei Gakuin University, bulletin of psychological science research (ISSN:21876355)

巻号頁・発行日

vol.42, pp.1-5, 2016-03

著者

N. Y.

出版者

公益社団法人 日本農芸化学会

雑誌

日本農芸化学会誌 (ISSN:00021407)

巻号頁・発行日

vol.56, no.2, pp.157-157, 1982 (Released:2008-11-21)

著者

井之口 有一 中井 和子 堀井 令以知 Y. Inokuti K. Nakai R. Horii

雑誌

京都府立大學學術報告. 人文 = The scientific report of Kyoto Prefectural University. Humanistic science (ISSN:00757381)

巻号頁・発行日

vol.14, pp.38_a-21_a, 1962-10-20

著者

Nakano M. Kondo Y. Owada K. Ueda N.

出版者

一般社団法人大学英語教育学会

雑誌

JACET全国大会要綱

巻号頁・発行日

vol.50, pp.46-47, 2011-08-29

著者

MIYAMOTO Y.

雑誌

Optical Amplifiers and Their Applications 1999

巻号頁・発行日

1999

被引用文献数

6 120

著者

丸山 隆司 稲田 哲雄 平岡 武 河内 清光 橋詰 雅 恒元 博 久津谷 譲 梅垣 洋一郎 マルヤマ タカシ イナダ テツオ ヒラオカ タケシ カワチ キヨミツ ハシズメ マサ ツネモト ヒロシ クツタニ ユズル ウメガキ ヨウイチロウ Maruyama T. Inada T. Hiraoka T. Kawachi K. Hashizume T. Tsunemoto H. Kutsutani Y. Umegawa Y.

出版者

日本医学放射線学会

雑誌

日本医学放射線学会雑誌 (ISSN:00480428)

巻号頁・発行日

vol.38, no.7, pp.633-642, 1978-07-25

著者

Donai H Murakami T Amano T Sogawa Y Yamauchi T

雑誌

MOLECULAR BRAIN RESEARCH (ISSN:0169328X)

巻号頁・発行日

vol.85, no.1, pp.189-199, 2000

被引用文献数

6 22

著者

N. Watanabe S. Matsusawa Y. Miyato H. Itozaki

出版者

(公社)日本磁気学会

雑誌

Journal of the Magnetics Society of Japan (ISSN:18822924)

巻号頁・発行日

vol.37, no.3-2, pp.235-238, 2013-05-01 (Released:2013-05-23)

参考文献数

7

被引用文献数

2 6

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We measured the high-resolution magnetic images using an STM-SQUID microscope that combines a high-Tc superconducting quantum interference device (SQUID) with a scanning tunneling microscope (STM). In the STM-SQUID microscope, the STM probe plays the important role of a flux guide and is responsible for tunneling current detection. Therefore, it is essential to investigate the probe itself in order to improve the magnetic image resolution. We optimized the electrochemical polishing condition to realize the fine probe with a tip radius of 50 nm or less. We fabricated the various shaped probes by controlling the voltage during sharpening. The tip radius of 50 nm or less was achieved when the probe tip was sharpened at the applied voltage of 30 V. We then measured the magnetic images of typical magnetic materials, such as a steel sample and nickel thin films, using the probe with a tip radius of 50 nm or less. The magnetic domain structures were observed clearly.

著者

Q. Tang H.Y. Wang H. Chen P. Li X.W. Tang T. Katsumi

出版者

公益社団法人 地盤工学会

雑誌

Japanese Geotechnical Society Special Publication (ISSN:21888027)

巻号頁・発行日

vol.2, no.53, pp.1845-1848, 2016-01-31 (Released:2016-01-29)

参考文献数

23

被引用文献数

1

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This paper studies the effects of bio-clogging on hydraulic conductivity of compacted soils used as landfill liners. Landfill leachate contains a large amount of microorganism and bacterial biomass, which was likely to cause bio-clogging in landfill liners. To interpret the effect of bio-clogging on hydraulic property of compacted clays, in this study, a series of laboratory-scale hydraulic conductivity tests were conducted. The long term hydraulic conductivity of compacted clays was measured with distilled water, landfill leachate and one type of nutrient solution. The laboratory test results show that the hydraulic conductivity of compacted clays permeated with distilled water stabilized at approximately 3.77 × 10-8 cm/s, and the hydraulic conductivity of compacted clays permeated with landfill leachate or nutrient solution ranged between 1.1 × 10-8 cm/s and 5.22 × 10-9 cm/s. Such a significant difference was attributed to the effect of bio-clogging. The microorganism and bacterial biomass reduced the hydraulic conductivity up to one order of magnitude. This study indicated that the bio-clogging is approximately a feasible method to create low-cost and low-hydraulic conductivity barriers by using locally available clayed soils.

著者

鈴木 洋一郎 Suzuki Y.

出版者

名古屋大学教育学部附属中学校 : 名古屋大学教育学部附属高等学校

雑誌

名古屋大学教育学部附属中高等学校紀要 (ISSN:03874761)

巻号頁・発行日

vol.15, pp.83-87, 1970-03-25 (Released:2006-01-06)

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国立情報学研究所で電子化したコンテンツを使用している。

著者

Acharya BS Actis M Aghajani T Agnetta G Aguilar J Aharonian F Ajello M Akhperjanian A Alcubierre M Aleksic J Alfaro R Aliu E Allafort AJ Allan D Allekotte I Amato E Anderson J Anguner EO Antonelli LA Antoranz P Aravantinos A Arlen T Armstrong T Arnaldi H Arrabito L Asano K Ashton T Asorey HG Awane Y Baba H Babic A Baby N Bahr J Bais A Baixeras C Bajtlik S Balbo M Balis D Balkowski C Bamba A Bandiera R Barber A Barbier C Barcelo M Barnacka A Barnstedt J de Almeida UB Barrio JA Basili A Basso S Bastieri D Bauer C Baushev A Becerra J Becherini Y Bechtol KC Tjus JB Beckmann V Bednarek W Behera B Belluso M Benbow W Berdugo J Berger K Bernard F Bernardino T Bernlohr K Bhat N Bhattacharyya S Bigongiari C Biland A Billotta S Bird T Birsin E Bissaldi E Biteau J Bitossi M Blake S Bigas OB Blasi P Bobkov A Boccone V Boettcher M Bogacz L Bogart J Bogdan M Boisson C Gargallo JB Bolmont J Bonanno G Bonardi A Bonev T Bonifacio P Bonnoli G Bordas P Borgland A Borkowski J Bose R Botner O Bottani A Bouchet L Bourgeat M Boutonnet C Bouvier A Brau-Nogue S Braun I Bretz T Briggs M Bringmann T Brook P Brun P Brunetti L Buanes T Buckley J Buehler R Bugaev V Bulgarelli A Bulik T Busetto G Buson S Byrum K Cailles M Cameron R Camprecios J Canestrari R Cantu S Capalbi M Caraveo P Carmona E Carosi A Carr J Carton PH Casanova S Casiraghi M Catalano O Cavazzani S Cazaux S Cerruti M Chabanne E Chadwick P Champion C Chen A Chiang J Chiappetti L Chikawa M Chitnis VR Chollet F Chudoba J Cieslar M Cillis A Cohen-Tanugi J Colafrancesco S Colin P Calome J Colonges S Compin M Conconi P Conforti V Connaughton V Conrad J Contreras JL Coppi P Corona P Corti D Cortina J Cossio L Costantini H Cotter G Courty B Couturier S Covino S Crimi G Criswell SJ Croston J Cusumano G Dafonseca M Dale O Daniel M Darling J Davids I Dazzi F De Angelis A De Caprio V De Frondat F Dal Pino EMD de la Calle I De La Vega GA Lopez RD De Lotto B De Luca A Neto JRTD de Naurois M de Oliveira Y Wilhelmi ED de Souza V Decerprit G Decock G Deil C Delagnes E Deleglise G Delgado C Della Volpe D Demange P Depaola G Dettlaff A Di Paola A Di Pierro F Diaz C Dick J Dickherber R Dickinson H Diez-Blanco V Digel S Dimitrov D Disset G Djannati-Atai A Doert M Dohmke M Domainko W Prester DD Donat A Dorner D Doro M Dournaux JL Drake G Dravins D Drury L Dubois F Dubois R Dubus G Dufour C Dumas D Dumm J Durand D Dyks J Dyrda M Ebr J Edy E Egberts K Eger P Einecke S Eleftheriadis C Elles S Emmanoulopoulos D Engelhaupt D Enomoto R Ernenwein JP Errando M Etchegoyen A Evans P Falcone A Fantinel D Farakos K Farnier C Fasola G Favill B Fede E Federici S Fegan S Feinstein F Ferenc D Ferrando P Fesquet M Fiasson A Fillin-Martino E Fink D Finley C Finley JP Fiorini M Curcoll RF Flores H Florin D Focke W Fohr C Fokitis E Font L Fontaine G Fornasa M Forster A Fortson L Fouque N Franckowiak A Fransson C Fraser G Frei R Albuquerque IFM Fresnillo L Fruck C Fujita Y Fukazawa Y Fukui Y Funk S Gabele W Gabici S Gabriele R Gadola A Galante N Gall D Gallant Y Gamez-Garcia J Garcia B Lopez RG Gardiol D Garrido D Garrido L Gascon D Gaug M Gaweda J Gebremedhin L Geffroy N Gerard L Ghedina A Ghigo M Giannakaki E Gianotti F Giarrusso S Giavitto G Giebels B Gika V Giommi P Girard N Giro E Giuliani A Glanzman T Glicenstein JF Godinovic N Golev V Berisso MG Gomez-Ortega J Gonzalez MM Gonzalez A Gonzalez F Munoz AG Gothe KS Gougerot M Graciani R Grandi P Granena F Granot J Grasseau G Gredig R Green A Greenshaw T Gregoire T Grimm O Grube J Grudzinska M Gruev V Grunewald S Grygorczuk J Guarino V Gunji S Gyuk G Hadasch D Hagiwara R Hahn J Hakansson N Hallgren A Heras NH Hara S Hardcastle MJ Harris J Hassan T Hatanaka K Haubold T Haupt A Hayakawa T Hayashida M Heller R Henault F Henri G Hermann G Hermel R Herrero A Hidaka N Hinton J Hoffmann D Hofmann W Hofverberg P Holder J Horns D Horville D Houles J Hrabovsky M Hrupec D Huan H Huber B Huet JM Hughes G Humensky TB Huovelin J Ibarra A Illa JM Impiombato D Incorvaia S Inoue S Inoue Y Ioka K Ismailova E Jablonski C Jacholkowska A Jamrozy M Janiak M Jean P Jeanney C Jimenez JJ Jogler T Johnson T Journet L Juffroy C Jung I Kaaret P Kabuki S Kagaya M Kakuwa J Kalkuhl C Kankanyan R Karastergiou A Karcher K Karczewski M Karkar S Kasperek A Kastana D Katagiri H Kataoka J Katarzynski K Katz U Kawanaka N Kellner-Leidel B Kelly H Kendziorra E Khelifi B Kieda DB Kifune T Kihm T Kishimoto T Kitamoto K Kluzniak W Knapic C Knapp J Knodlseder J Kock F Kocot J Kodani K Kohne JH Kohri K Kokkotas K Kolitzus D Komin N Kominis I Konno Y Koppel H Korohoda P Kosack K Koss G Kossakowski R Kostka P Koul R Kowal G Koyama S Koziol J Krahenbuhl T Krause J Krawzcynski H Krennrich F Krepps A Kretzschmann A Krobot R Krueger P Kubo H Kudryavtsev VA Kushida J Kuznetsov A La Barbera A La Palombara N La Parola V La Rosa G Lacombe K Lamanna G Lande J Languignon D Lapington J Laporte P Lavalley C Le Flour T Le Padellec A Lee SH Lee WH de Oliveira MAL Lelas D Lenain JP Leopold DJ Lerch T Lessio L Lieunard B Lindfors E Liolios A Lipniacka A Lockart H Lohse T Lombardi S Lopatin A Lopez M Lopez-Coto R Lopez-Oramas A Lorca A Lorenz E Lubinski P Lucarelli F Ludecke H Ludwin J Luque-Escamilla PL Lustermann W Luz O Lyard E Maccarone MC Maccarone TJ Madejski GM Madhavan A Mahabir M Maier G Majumdar P Malaguti G Maltezos S Manalaysay A Mancilla A Mandat D Maneva G Mangano A Manigot P Mannheim K Manthos I Maragos N Marcowith A Mariotti M Marisaldi M Markoff S Marszalek A Martens C Marti J Martin JM Martin P Martinez G Martinez F Martinez M Masserot A Mastichiadis A Mathieu A Matsumoto H Mattana F Mattiazzo S Maurin G Maxfield S Maya J Mazin D Mc Comb L McCubbin N McHardy I McKay R Medina C Melioli C Melkumyan D Mereghetti S Mertsch P Meucci M Michalowski J Micolon P Mihailidis A Mineo T Minuti M Mirabal N Mirabel F Miranda JM Mirzoyan R Mizuno T Moal B Moderski R Mognet I Molinari E Molinaro M Montaruli T Monteiro I Moore P Olaizola AM Mordalska M Morello C Mori K Mottez F Moudden Y Moulin E Mrusek I Mukherjee R Munar-Adrover P Muraishi H Murase K Murphy A Nagataki S Naito T Nakajima D Nakamori T Nakayama K Naumann C Naumann D Naumann-Godo M Nayman P Nedbal D Neise D Nellen L Neustroev V Neyroud N Nicastro L Nicolau-Kuklinski J Niedzwiecki A Niemiec J Nieto D Nikolaidis A Nishijima K Nolan S Northrop R Nosek D Nowak N Nozato A O'Brien P Ohira Y Ohishi M Ohm S Ohoka H Okuda T Okumura A Olive JF Ong RA Orito R Orr M Osborne J Ostrowski M Otero LA Otte N Ovcharov E Oya I Ozieblo A Padilla L Paiano S Paillot D Paizis A Palanque S Palatka M Pallota J Panagiotidis K Panazol JL Paneque D Panter M Paoletti R Papayannis A Papyan G Paredes JM Pareschi G Parks G Parraud JM Parsons D Arribas MP Pech M Pedaletti G Pelassa V Pelat D Perez MDC Persic M Petrucci PO Peyaud B Pichel A Pita S Pizzolato F Platos L Platzer R Pogosyan L Pohl M Pojmanski G Ponz JD Potter W Poutanen J Prandini E Prast J Preece R Profeti F Prokoph H Prouza M Proyetti M Puerto-Gimenez I Puhlhofer G Puljak I Punch M Pyziol R Quel EJ Quinn J Quirrenbach A Racero E Rajda PJ Ramon P Rando R Rannot RC Rataj M Raue M Reardon P Reimann O Reimer A Reimer O Reitberger K Renaud M Renner S Reville B Rhode W Ribo M Ribordy M Richer MG Rico J Ridky J Rieger F Ringegni P Ripken J Ristori PR Riviere A Rivoire S Rob L Roeser U Rohlfs R Rojas G Romano P Romaszkan W Romero GE Rosen S Lees SR Ross D Rouaix G Rousselle J Rousselle S Rovero AC Roy F Royer S Rudak B Rulten C Rupinski M Russo F Ryde F Sacco B Saemann EO Saggion A Safiakian V Saito K Saito T Saito Y Sakaki N Sakonaka R Salini A Sanchez F Sanchez-Conde M Sandoval A Sandaker H Sant'Ambrogio E Santangelo A Santos EM Sanuy A Sapozhnikov L Sarkar S Sartore N Sasaki H Satalecka K Sawada M Scalzotto V Scapin V Scarcioffolo M Schafer J Schanz T Schlenstedt S Schlickeiser R Schmidt T Schmoll J Schovanek P Schroedter M Schultz C Schultze J Schulz A Schure K Schwab T Schwanke U Schwarz J Schwarzburg S Schweizer T Schwemmer S Segreto A Seiradakis JH Sembroski GH Seweryn K Sharma M Shayduk M Shellard RC Shi J Shibata T Shibuya A Shum E Sidoli L Sidz M Sieiro J Sikora M Silk J Sillanpaa A Singh BB Sitarek J Skole C Smareglia R Smith A Smith D Smith J Smith N Sobczynska D Sol H Sottile G Sowinski M Spanier F Spiga D Spyrou S Stamatescu V Stamerra A Starling R Stawarz L Steenkamp R Stegmann C Steiner S Stergioulas N Sternberger R Sterzel M Stinzing F Stodulski M Straumann U Strazzeri E Stringhetti L Suarez A Suchenek M Sugawara R Sulanke KH Sun S Supanitsky AD Suric T Sutcliffe P Sykes J Szanecki M Szepieniec T Szostek A Tagliaferri G Tajima H Takahashi H Takahashi K Takalo L Takami H Talbot C Tammi J Tanaka M Tanaka S Tasan J Tavani M Tavernet JP Tejedor LA Telezhinsky I Temnikov P Tenzer C Terada Y Terrier R Teshima M Testa V Tezier D Thuermann D Tibaldo L Tibolla O Tiengo A Tluczykont M Peixoto CJT Tokanai F Tokarz M Toma K Torii K Tornikoski M Torres DF Torres M Tosti G Totani T Toussenel C Tovmassian G Travnicek P Trifoglio M Troyano I Tsinganos K Ueno H Umehara K Upadhya SS Usher T Uslenghi M Valdes-Galicia JF Vallania P Vallejo G van Driel W van Eldik C Vandenbrouke J Vanderwalt J Vankov H Vasileiadis G Vassiliev V Veberic D Vegas I Vercellone S Vergani S Veyssiere C Vialle JP Viana A Videla M Vincent P Vincent S Vink J Vlahakis N Vlahos L Vogler P Vollhardt A von Gunten HP Vorobiov S Vuerli C Waegebaert V Wagner R Wagner RG Wagner S Wakely SP Walter R Walther T Warda K Warwick R Wawer P Wawrzaszek R Webb N Wegner P Weinstein A Weitzel Q Welsing R Werner M Wetteskind H White R Wierzcholska A Wiesand S Wilkinson M Williams DA Willingale R Winiarski K Wischnewski R Wisniewski L Wood M Wornlein A Xiong Q Yadav KK Yamamoto H Yamamoto T Yamazaki R Yanagita S Yebras JM Yelos D Yoshida A Yoshida T Yoshikoshi T Zabalza V Zacharias M Zajczyk A Zanin R Zdziarski A Zech A Zhao A Zhou X Zietara K Ziolkowski J Ziolkowski P Zitelli V Zurbach C Zychowski P

雑誌

ASTROPARTICLE PHYSICS (ISSN:09276505)

巻号頁・発行日

vol.43, pp.3-18, 2013

著者

María Asunción Esteve-Pastor Amaya García-Fernández Manuel Macías Francisco Sogorb Mariano Valdés Vanessa Roldán Javier Muñiz Lina Badimon Inmaculada Roldán Vicente Bertomeu-Martínez Ángel Cequier Gregory Y.H. Lip Manuel Anguita Francisco Marín on behalf of FANTASIIA Investigators

出版者

日本循環器学会

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

vol.80, no.10, pp.2102-2108, 2016-09-23 (Released:2016-09-23)

参考文献数

39

被引用文献数

6 19

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Background:Several bleeding risk scores have been validated in patients with atrial fibrillation (AF). The ORBIT score has been recently proposed as a simple score with the best ability to predict major bleeding. The present study aimed to test the hypothesis that the ORBIT score was superior to the HAS-BLED score for predicting major bleeding and death in “real world” anticoagulated AF patients.Methods and Results:We analyzed the predictive performance for bleeding and death of 406 AF patients who underwent 571 electrical cardioversion procedures and 1,276 patients with permanent/persistent AF from the FANTASIIA registry. In the cardioversion population, 21 patients had major bleeding events and 26 patients died. The predictive performance for major bleeding of HAS-BLED and ORBIT were not significantly different (c-statistics 0.77 (95% CI 0.66–0.88) and 0.82 (95% CI 0.77–0.93), respectively; P=0.080). For the FANTASIIA population, 46 patients had major bleeding events and 50 patients died. The predictive performances for major bleeding of HAS-BLED and ORBIT were not significantly different (c-statistics 0.63 (95% CI 0.56–0.71) and 0.70 (95% CI 0.62–0.77), respectively; P=0.116). For death, the predictive performances of HAS-BLED and ORBIT were not significantly different in both populations. The ORBIT score categorized most patients as “low risk”.Conclusions:Despite the original claims in its derivation paper, the ORBIT score was not superior to HAS-BLED for predicting major bleeding and death in a “real world” oral anticoagulated AF population. (Circ J 2016; 80: 2102–2108)

著者

You D. Fukuzawa H. Sakakibara Y. Takanashi T. Ito Y. Maliyar G. G. Motomura K. Nagaya K. Nishiyama T. Asa K. Sato Y. Saito N. Oura M. Schöffler M. Kastirke G. Hergenhahn U. Stumpf V. Gokhberg K. Kuleff A. I. Cederbaum L. S. Ueda K

出版者

Springer Nature

雑誌

Nature Communications (ISSN:20411723)

巻号頁・発行日

vol.8, 2017-01-30

被引用文献数

24

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安定なイオンが周囲の原子の電子をキャッチ&リリース! --X線照射による生体分子損傷の機構解明に貢献--. 京都大学プレスリリース. 2017-02-01.

著者

Y-h. Taguchi

出版者

The Molecular Biology Society of Japan

雑誌

The 39th Annual Meeting of the Molecular Biology Society of Japan

巻号頁・発行日

2016-11-08