著者

福島 大志 西川 敦 宮崎 文夫 関野 正樹 安室 喜弘 松崎 大河 細見 晃一 齋藤 洋一

出版者

公益社団法人 日本生体医工学会

雑誌

生体医工学 (ISSN:1347443X)

巻号頁・発行日

vol.49, no.1, pp.122-131, 2011-02-10 (Released:2011-12-13)

参考文献数

16

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Repetitive Transcranial Magnetic Stimulation (rTMS) is effective for intractable diseases of the nervous system. As the effects of rTMS last only several hours, rTMS therapies need to be continued daily. Under present circumstances, it is difficult to use rTMS in patients' home, because only experienced physicians in limited hospitals can use the expensive and complicated rTMS system. Therefore, we developed a magnetic navigation system for home use of rTMS. The proposed system uses inexpensive and small magnetic sensors; hence it is suitable for home use. By using the proposed method, even people who have no medical knowledge and technique can easily navigate the coil to the optimal position preliminarily specified by expert physicians. Our system needs to collect some dataset which consists of magnetic field and the corresponding position of the coil at the patients' initial visit. Since it is bothersome to collect a large number of dataset, we reduced the dataset by approximation using multi-regression analysis.

著者

鈴木 良次

出版者

公益社団法人 日本生体医工学会

雑誌

生体医工学 (ISSN:1347443X)

巻号頁・発行日

vol.53, no.2, pp.61-62, 2015-04-10 (Released:2015-06-25)

著者

酒谷 薫

出版者

公益社団法人 日本生体医工学会

雑誌

生体医工学

巻号頁・発行日

vol.55, no.4, pp.308-308, 2017

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<p>厚生労働省は、団塊の世代が75歳以上となる2025年を目途に、高齢者の尊厳の保持と自立生活の支援の目的のもとで、可能な限り住み慣れた地域で、自分らしい暮らしを人生の最期まで続けることができるよう、地域の包括的な支援・サービス提供体制(「地域包括ケアシステム」)の構築を推進している。我々は、IoT/BD/AIの先端技術を応用した地域包括ケアシステムを開発し、福島県郡山市のモデル地区で実証実験を行っている(2016年4月~)。本オーガナイズドセッションでは、我々が開発したシステム及び実証実験の途中結果について報告し、地域包括ケアシステムにおけるIoT/BD/AIの先端技術の有用性について検討する。本システムは、ICTとセンサー技術による見守りシステム(睡眠センサー、水道センサー)とNIRSによる脳と心の見える化により構成されている。本システムをモデル地区の高齢者家庭に設置し、睡眠時の心拍数、呼吸数、離床、及び水道使用量を遠隔でモニターしている。さらに、定期的に公民館にて、心理テスト(STAI,MMSE)及びNIRSによる脳機能計測を実施し、参加住民の健康相談に応じている。本講演では、実証実験の結果を供覧し、IoT/BD/AIを導入した次世代地域包括ケアシステムの有用性と問題点について考察する。</p>

著者

中尾 誠 赤土 和也 山崎 健一 寺田 堂彦 藤里 俊哉 吉浦 昌彦 筒井 博司

出版者

公益社団法人 日本生体医工学会

雑誌

生体医工学 (ISSN:1347443X)

巻号頁・発行日

vol.47, no.6, pp.560-565, 2009-12-10 (Released:2010-07-21)

参考文献数

8

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If we regard skeletal muscle as an actuator, we see it has excellent flexibility and efficiency, properties that artificial actuators such as electric motors or mechanical engines do not have. We have been researching the creation of miniaturized bio-actuators that use cultured skeletal muscle. We reported that stimulation was very important to culture myoblast and to develop skeletal muscle. We obtained skeletal muscle by cultivating C2C12 cells using unidirectional mechanical stimulation. We developed a Bio-Actuator System as a mode for a skeletal muscle system in which this cultured skeletal muscle was used as actuator unit. This Bio-Actuator System was made to imitate the musculoskeletal system and consisted of one joint, two arms, one flexor muscle and one extensor muscle. One arm was fixed on the base, and the other arm was able to rotate freely about the joint axis. Because skeletal muscle can only contract, we used cultured skeletal muscle as flexor muscle and sliced silicon elastic sheet as extensor muscle. Experiments were conducted with this Bio-Actuator System in a culture medium. By applying pulsed voltage to the culture medium, the bio-actuator unit was contracted and relaxed. By repeating these contractions and expansions, we observed that the tip of the arm vibrated periodically.

著者

眞田 慎 岡田 志麻

出版者

公益社団法人 日本生体医工学会

雑誌

生体医工学

巻号頁・発行日

vol.55, no.3, pp.224-224, 2017

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<p>現在の日本において,聴覚・言語障害者が360,000人であるのに対して手話通訳士は3,406人となっており,聴覚障害者に比べて手話通訳士の人数が少なくなっている.この状況は,聴覚障害者と健聴者間の円滑なコミュニケーションを困難にし,聴覚障害者の積極的な社会参加を妨げる要因の一つとなっている.この問題を解決する手段として,本研究ではKinect v2を用いた手話通訳士を介さないリアルタイム手話通訳システムの開発を行った.また,手話動作の認識において動作者の表情が重要なパラメータとなることから,本システムでは腕の動きと手の形,表情の3つの状態を認識し,それぞれArms Motions,Hand States,Facial Expressionsパラメータとして動作データの取得を行う.さらに,取得した各パラメータデータの組み合わせから手話動作を特定し,通訳結果をモニター上にテキストで表示する.本研究では,各パラメータ認識手法の検証実験と通訳システムの実証実験を行った.検証実験の結果において,Arms Motionsで100%,Hand Statesで86%,Facial Expressionsで88%の認識精度が得られた.また,実証実験の結果において,3つのパラメータ認識手法を組み合わせた手話通訳システムを用いた手話単語の通訳に成功した.以上により,本システムの手話通訳における有効性が示された.</p>

著者

和宇慶 真 小濱 剛 吉田 久

出版者

公益社団法人 日本生体医工学会

雑誌

生体医工学 (ISSN:1347443X)

巻号頁・発行日

vol.55Annual, no.3PM-Abstract, pp.219-219, 2017 (Released:2017-09-13)

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脳活動を非侵襲的に計測する手法としてfNIRSが広く利用されている。これは脳神経活動により発生する酸素消費を、近赤外光を用いて血中ヘモグロビン濃度の変化として観測するものである。しかしながら、fNIRS観測信号には生理学的要因によるものや、身体の動きに伴う全身性の血流量変化が含まれる。本研究ではこれらの問題に対し、Yamadaらの分離モデルを用いて観測信号を機能成分と全身成分に分離した。また、先行研究では機能成分の係数をグローバルな値として-0.6に固定していたが、計測部位によって有意な差があったため、全ての係数を数値計算により動的に決定した。このモデルを用いて観測信号を分離した結果、被験者の動きによる大きな血流量変化が全身成分として分離され、機能成分のベースラインが安定した。また、機能成分の係数を固定した場合に比べ、全ての観測信号において相互情報量が小さくなった。この結果は、計測領域やタスクによって最適な係数が異なる可能性があるため、検討の余地があると考えられる。

著者

加藤 雄斗 鈴木 健嗣

出版者

公益社団法人 日本生体医工学会

雑誌

生体医工学 (ISSN:1347443X)

巻号頁・発行日

vol.55Annual, no.Proc, pp.508-509, 2017-05-03 (Released:2017-09-13)

参考文献数

4

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Myoelectric upper limb prosthesis has some problems such as its stability of contact condition or determination of the optimum position of electrodes. This study reports the Development of a socket integrated with array electrode for myoelectric upper limb prosthesis. This array electrode, which was made of conductive cloth, can cope with various shapes of stumps of amputees. The advanced socket integrated with the developed array electrodes has capabilities to determine the appropriate positions of electrodes without much considering the location. The prototype is valid for detecting EMG signals for the control of myoelectric upper limb prosthesis.

著者

丸山 敏弘 塩澤 成弘 牧川 方昭

出版者

公益社団法人 日本生体医工学会

雑誌

生体医工学 (ISSN:1347443X)

巻号頁・発行日

vol.44, no.1, pp.177-183, 2006 (Released:2008-02-27)

参考文献数

11

被引用文献数

1

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Recently, much research has been done to evaluate mental stress based on heartbeat fluctuation and lower restraint, and a non-invasive ECG measurement method is been expected to be able to record the heartbeat during daily life. In this study, a new ECG measuring method that uses capacity coupled electrodes without any reference electrode is proposed. In this paper, five different settings of signal electrodes and ground connections were compared: One capacity coupled signal electrode with no ground electrode, two capacity coupled signal electrodes with no ground electrode, two capacity coupled signal electrodes with a common ground electrode on the skin, one capacity coupled signal electrode with one capacity coupled ground electrode, and two capacity coupled signal electrodes with the amplifier grounded. We also examined our new ECG measurement method under different electrical environments: in a noise-filled laboratory, outdoors with no commercial electrical power nearby, and inside a car with the engine and air conditioner operating. As a result, our new measurement method proved to be effective for obtaining ECG signals during daily life.

著者

川口 浩和 小林 哲生

出版者

公益社団法人 日本生体医工学会

雑誌

生体医工学 (ISSN:1347443X)

巻号頁・発行日

vol.49, no.4, pp.551-557, 2011-08-10 (Released:2012-01-18)

参考文献数

10

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Eye-blink activities are major artifacts for electroencephalogram (EEG) measurements. Various methods have been reported for removing eye-blink artifacts from EEGs. Almost all previous methods focus on how much eye-blink artifacts are removed. However, they concurrently remove a part of EEGs together with eye-blink artifacts. Instead, we focus on how much true EEGs remains, and proposed a localized removal method for eye-blink artifacts. The proposed method is based on the combinations of independent component analysis (ICA). empirical mode decomposition (EMD) and Kalman filter. In addition, we proposed a novel simulation model to test performances of the proposed and previous methods. This simulation model indicates that the proposed method shows the best performance and reduces information loss of EEGs than previous methods.

著者

徳重 あつ子 阿曽 洋子 伊部 亜希 岡 みゆき 片山 恵

出版者

公益社団法人 日本生体医工学会

雑誌

生体医工学 (ISSN:1347443X)

巻号頁・発行日

vol.47, no.1, pp.15-27, 2009-02-10 (Released:2009-08-13)

参考文献数

43

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This study examined the effect of sitting positions on cerebral activation for people in bed and analyzed postural significance. The subjects were 30 healthy adults. We recorded their EEGs in α and β band and performed a subjective test in supine and sitting positions with the head of the bed elevated at 30° and 80°. First, measurements were made in the supine position for 5 minutes, and the head of the bed was then elevated. Measurement continued in the sitting position for 15 minutes at 3 stages: Stages 1, 2, and 3. Using the supine position as a baseline, we compared the supine and sitting positions. We also compared the two angles, 30° and 80°. The EEG showed a significant increase at the 80° for all measured regions and intervals, and a partially significant increase was noted at 30°. Comparing the effect of different angles confirmed the significance of 80° at Stages 1 and 2. Moreover retention time of cerebral activation at 80° is longer than that at 30°. The subjective test also confirmed a higher degree of awakening in the sitting position and in a bed at 80°. Consequently, the effect of the sitting position verified cerebral activation.

著者

鶴岡 典子 河野 隆宏 松永 忠雄 永富 良一 芳賀 洋一

出版者

公益社団法人 日本生体医工学会

雑誌

生体医工学 (ISSN:1347443X)

巻号頁・発行日

vol.54, no.5, pp.207-217, 2016-10-10 (Released:2017-01-14)

参考文献数

20

被引用文献数

1

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Quantitative measurement of sweating rate is a useful indicator of the state of autonomic nerves and related factors such as stress response or body temperature regulation. Specifically, it is known that mental stress increases mental sweating, and deep body temperature and dehydration increase thermal sweating. Therefore, continuous sweat measurement with a small sweating rate meter is expected to be useful for the management of mental stress as well as the prevention of heat stroke. In this study, two small sweating rate meters, one having high resolution and the other having a large dynamic range, were developed and used to measure mental sweating and thermal sweating. These devices determine the sweating rate by the conventional method, which measures the humidity difference between ambient air and air moistened by sweat. Measurement resolution and dynamic range can be adjusted by controlling the air flow rate. The device for measuring mental sweating rate consists of a main body, which has an air pump and two humidity sensors, and a capsule connected to the main body by tubes in which air flows. The device for measuring thermal sweating rate has a pump and two humidity sensors, an aperture instead of a capsule, and a flow channel on a flexible substrate. The mental sweating rates during arithmetic and speech tasks were measured on the plantar aspect of the big toe using the mental sweating rate meter. The present study on part of the sole showed two sweating types ; a reaction type and a low-reaction type. During the mental stress tasks, sweating rate increased by 0.43 mg/min/cm2 compared to that at rest in reaction type subjects, but by less than 0.1 mg/min/cm2 in low-reaction type subjects, showing very low responses to stimulations. The thermal sweating rate during immersion of the lower legs in warm water was measured using the thermal sweating meter worn on the forearm. Sweating rate increased by approximately 0.4 mg/min/cm2 on average due to thermal stress, and was also successfully measured. These results show that the small sweating rate meters developed in this study can be used for measuring mental and thermal sweating rates.

著者

高橋 一生 瀧 宏文 山内 正憲 金井 浩

出版者

一般社団法人 日本生体医工学会

雑誌

生体医工学

巻号頁・発行日

vol.54, no.26, pp.S86-S86, 2016

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<p>Since ultrasonography has insufficient performance in depicting the vertebral surface, most examiners perform epidural anesthesia using landmarks on the back without ultrasonography. The final purpose of this study is to improve the performance by ultrasonography in depicting thoracic vertebral surface.RPM method is one of the bi-static imaging methods, it estimates the reflection point on a target surface by intersections of plural ellipses, where the focal points of an ellipse are the position of a transmit element and that of a receive element.We investigated the performance of the RPM method in an experimental study using a phantom with a concave surface of a 2 cm curvature radius. The depicted region of concave surface acquired using the conventional method and the RPM method was approximately 14.8% and 17.7% of the whole concave surface, respectively. This result indicates that the RPM method has high performance in depicting sloping target boundary.</p>

著者

土井 俊祐 井出 博生 竹内 公一 藤田 伸輔

出版者

公益社団法人 日本生体医工学会

雑誌

生体医工学 (ISSN:1347443X)

巻号頁・発行日

vol.55, no.1, pp.45-49, 2017-02-10 (Released:2017-04-25)

参考文献数

9

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Personal Health Records (PHRs), a system that enables people to manage, share, and apply personal healthcare data using information and communication technology, is expected to be an effective method to realize a vigorous society with longevity. However, it is not clear how the user's opt-in agreement and self-management of personal data may be achieved. Thus, we developed a new method to optimize opt-in agreement and access control for users in a PHR developed at Chiba University, the Social Health Assist Chiba (SHACHI). In SHACHI, participating facilities such as hospitals, clinics, pharmacies, and nursing care services display a user's unique two-dimensional bar code on a web browser. The user reads the bar code by him/herself using the “SHACHI App,” which is installed on his/her smart phone beforehand. SHACHI considers this process to signify the user's opt-in agreement. Moreover, users can retract or resume this agreement using the SHACHI App at any time. This system enables the users to self-manage personal data in PHRs. The new system satisfies government requirements and the conditions required for PHR presented in a previous study. This new system can be adopted easily by other PHRs. We plan to identify the required functionalities of standard PHRs and secondary utilization of data stored in PHRs which may be managed through the new system.

著者

新川 拓也 河内 了輔 萩野 知香 西 恵理 高田 慶応 湊 小太郎

出版者

一般社団法人 日本生体医工学会

雑誌

生体医工学 (ISSN:1347443X)

巻号頁・発行日

vol.49, no.3, pp.501-507, 2011

被引用文献数

1

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The aim of this study was to clarify the mechanical action of the infant tongue during sucking. Therefore we developed an artificial nipple that contained multiple small built-in force sensors which was capable of measuring tongue-artificial nipple contact pressure in real-time. A force sensor was a cantilever structure composed of a thin stainless steel beam and all-purpose foil strain gauges attached to the surface of the beam. The signals obtained from the force sensor were amplified, and were transferred to a PC via a USB port. Using this system, measurements were taken in three infants. The output waveform was observed in all subjects, and the rate of sucking was about two times per second. In addition, the pressure waveform indicated peristalsis-like movement of tongue in infants with established oral feeding. This system can quantitatively measure individual differences in tongue movement.

著者

熊橋 智史 野川 雅道 内藤 尚 田中 志信

出版者

公益社団法人 日本生体医工学会

雑誌

生体医工学 (ISSN:1347443X)

巻号頁・発行日

vol.54, no.26, pp.S109, 2016

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<p>Toward a development of noninvasive tissue oxygen consumption monitoring method, we propose an arteriovenous blood oxygen saturation measurement based on near-infrared spectroscopy. For arterial blood oxygen saturation measurement, we employ a conventional arterial blood oxygen saturation measurement method, pulse oximetry. Then, for venous blood oxygen saturation measurement, based on a similar principle of pulse oximetry, we developed a new venous blood photoplethysmographic oximetry using cyclic cuff compression technique (mean pressure: 10mmHg with 10mmHg amplitude, cyclic frequency: 0.1Hz). The noninvasive arteriovenous blood oxygen saturation measurement system comprises two-wavelength, 750/830nm. The calibration curve of blood oxygen saturation measurement was calibrated, without blood-drawing, using theoretical photon propagation model based on radiative transfer. The newly designed noninvasive arteriovenous blood oxygen saturation measurement system was evaluated with healthy subjects' forearms during isometric hand-grip exercise. The noninvasive measurement system could offer reasonable blood oxygen saturation changes during the exercise and following resting period.</p>

著者

中村 のぞみ 栁澤 一機 綱島 均 成田 奈緒子

出版者

公益社団法人 日本生体医工学会

雑誌

生体医工学 (ISSN:1347443X)

巻号頁・発行日

vol.53, no.Supplement, pp.S383-S386, 2015 (Released:2016-06-18)

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BCI (Brain Computer Interface) is a system that controls machines and devices by extracting neural information from human brain activity and inputting it to machines. BCI system can be used to feedback the brain activity level to users so that they can control their brain activity, which is called NFB (Neurofeedback). The NFB system is expected to make better condition for ASD (Autistic spectrum disorder) and ADHD (Attention deficit hyperactivity disorder) patients. The NIRS-NFB system measures the brain activity by using portable NIRS. The measured brain activity can be inputted to various machines and devices (display monitor, toy car and video game). To evaluate the effectiveness of the developed system, we conducted experiments of NFB training for ASD participants. It is shown that more brain activity can be observed after the NFB training for ASD participants. Those results show that the developed system is effective in the NFB training for ASD participants.

著者

京相 雅樹

出版者

公益社団法人 日本生体医工学会

雑誌

生体医工学 (ISSN:1347443X)

巻号頁・発行日

vol.44, no.1, pp.47-53, 2006 (Released:2008-02-27)

参考文献数

101

出版者

公益社団法人 日本生体医工学会

雑誌

生体医工学 (ISSN:1347443X)

巻号頁・発行日

vol.45, no.Supplement1, pp.101-102, 2007-04-25 (Released:2011-09-05)

著者

清水 孝一

出版者

公益社団法人 日本生体医工学会

雑誌

生体医工学 (ISSN:1347443X)

巻号頁・発行日

vol.44, no.1, pp.1-2, 2006 (Released:2008-02-27)

被引用文献数

2

著者

池内 真志 生田 幸士

出版者

Japanese Society for Medical and Biological Engineering

雑誌

生体医工学 (ISSN:1347443X)

巻号頁・発行日

vol.43, no.4, pp.646-652, 2005

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The authors of this letter propose a novel "multi-layer hybrid scaffold" consisting of artificial blood capillary networks and cell-containing hydrogel for tissue engineering. The artificial blood capillary network was fabricated using a Membrane Micro Embossing (MeME) process, a unique, newly developed microfabrication process capable of fabricating freestanding thin polymer membrane micro-channels with both simplicity and high precision. With this process, a thin thermoplastic polymer membrane was placed on a deformable support substrate and embossed to fit 3D structures on a master mold by backpressure from the support. A one step heat-sealing method was used to successfully fabricate a highly branched "membrane micro-channel network" of biodegradable poly-lacticacid (PLA) micro-channels measuring 50 μm in width, 50 μm in depth, and 5 μm in wall thickness. The biocompatibility of the fabricated micro-channel was confirmed by culturing human umbilical vascular endothelial cells (HUVEC) on the micro-channel. This technology will provide a useful method for regenerating large organs in the future.