著者

小池 靖夫

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.80, no.9, pp.1338-1340, 1987-09-01 (Released:2011-11-04)

参考文献数

2

著者

大越 俊夫

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.99, no.11, pp.891-896, 2006-11-01

参考文献数

15

---

Abnormal sensations in the throat can be induced by a wide variety of causes, and therefore requires both mental and physical approaches to treatment. In addition, malignant tumors maybe detected in a small number of patients with complaints of abnormal sensations in the throat, and this must never be overlooked. While there have been numerous reports descring various tests, diagnostic methods for determining the causes of abnormal sensations in the throat as well as administration the of therapeutic drugs vary among facilities and few reports have investigated cases of abnormal sensations refractory to initial treatment. Furthermore, although the involvement of psychogenesis in this illness is not small, the extent of its involvement is extremely difficult to assess. While therapeutic determination using various psychological tests and the effects of mild tranquilizers has been attempted, clarification of the extent of psychogenic involvement in this illness remains difficult, as does the treatment of this illness as a psychosomatic illness in the field of otolaryngology.<br>Improvement in abnormal sensations in the throat is determined by changes in the subjective symptoms of the patient. Many reports on the treatment of abnormal sensations in the throat have focused on the effects of administering a specific drug in response to a defined cause of illness, and few have reported the final improvement rates of the patients included in these studies. In other words, it is important to investigate secondary and tertiary treatment methods and the extent to which abnormal sensations in the throat has been improved in patients with abnormal sensations refractory to initial treatment, as well as the appropriate course of action when improvements are not observed.

著者

甲斐 智朗

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.95, no.7, pp.679-684, 2002-07-01

参考文献数

9

被引用文献数

2 1

---

Two cases of psychogenic hearing loss in adults are presented with the process of their mental states. Case 1 was a 20-year-old male who complained of unilateral hearing loss and tinnitus on his left side after receiving a &ldquo;karate&rdquo; kick on his left temple. Considering the perforation of his left tympanic membrane, his left hearing level was much worse (77.5 dBHL). Later examination of ABR revealed the sensorineural system to be intact, and functional hearing loss was suspected. Further questions about his history disclosed that he was extremely unhappy in his job and wanted to leave his present employment. After discussion with psychiatrists, the diagnosis of psychogenic hearing loss was established.<br>Case 2 was a 23-year-old male who complained of right tinnitus after hearing rifle shooting during night time maneuvers in the Self Defense Forces. In spite of the normal appearances of his external and middle ear, his hearing level was 72.5dBHL. Being treated as acoustic trauma, ABR was performed and it resulted in a completely normal response. In this case, the diagnosis of psychogenic hearing loss was also established.<br>Especially in adults, psychogenic hearing loss is regarded as a kind of conversion disorder. In this disease, getting ill brings some &ldquo;gain&rdquo; to the patients. Admission to the hospital separates a patient from his unpleasant job and persons (secondary gain). This is almost compatible with the mental state of case 1. When their desires are converted to physical disorders and are appreciated by another person, they don't have to be concerned by their source of annoyance. Thus their mental states are stabilized (primary gain). This is almost compatible with the mental state of case 2.<br>When assessing patients of Psychogenic hearing loss, their mental states should be considered as there may be various processes involved in the disease.

著者

伊藤 信輔 小田原 修一 山口 勝矢 平野 実

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.82, no.12, pp.1719-1725, 1989-12-01 (Released:2011-11-04)

参考文献数

15

---

The relationship between the direction of rotation and the leg supporting the body in figure-skating was thought to be based on the cristo-spinal reflex. Skaters stand or jump with the leg of the same side as the rotation when turning around a vertical axis. This suggests that the movement of endolymphatic fluid towards the ampulla of the ipsilateral horizontal semicircular canal as the direction of rotation exerts a facilitatory action on the extensor neurons. On the other hand, they land on the ice with the opposite leg after turning in the air. This can be interpreted as a phenomenon similar to postrotatory nystagmus; that is, the ampullopetal flow takes place in the semicircular canal opposite to the rotation after cessation of turning, resulting in activation of this canal.

著者

荻野 敏 原田 保 坂口 喜清 柳 英博 丹生 真理子 仙波 治 入船 盛弘 田矢 直三 野入 輝久 坂本 邦彦 荻野 仁

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.91, no.2, pp.199-204, 1998-02-01 (Released:2011-11-04)

参考文献数

7

被引用文献数

4 6

---

Treatment of tinnitus is often difficult. In this study, we evaluated the effectiveness of a Chinese medicine, Gosha-jinki-gan, for the treatment of tinnitus. Forty-two cases, comprising a total of 58 ears, received Gosha-jinki-gan at a dose of 7.5 g a day for at least 4 weeks. Efficacy was evaluated on the basis of changes in symptoms before and after treatment. In total, twenty-seven out of 58 ears (46.6%) improved. The final improvement rate was higher in the group with hearing loss than in the group without hearing loss. It was also greater in the group without pre-treatment than in the group with pre-treatment, however, co-treatment did not influence the improvement rate. No adverse reactions were evident. From these results, it was thought that Gosha-jinki-gan might be useful in the treatment of tinnitus.

著者

山下 敏夫

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.83, no.8, pp.1314-1315, 1990-08-01 (Released:2011-11-04)

被引用文献数

1

著者

山田 弘之 久保 将彦 村井 須美子 坂倉 康夫

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.80, no.7, pp.1163-1168, 1987-07-01 (Released:2011-11-04)

参考文献数

12

---

Large doses of metoclopramide as an antiemetics were administered to 9 patients recieving cisplatin (CDDP) (50mg/m2) for head and neck cancers. Metoclopramide, 2mg/kg was administered four times intravenously on the first day of CDDP therapy and once a day on days 2-7. Neither emesis nor nausea occurred in 8 of the 9 patients (89%). Side effbcts were minimal: mild sleepiness(66.7%)and diarrhea(22.2%). It is concluded that the antiemetic effect of intravenous metoclopramide in large amounts can prevent cisplatin-induced emesis.

著者

松永 亨 山本 好一

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.78, no.11special, pp.2687-2692, 1985-11-25 (Released:2011-11-04)

参考文献数

14

---

This study was performed to determine whether electrical stimulation of the autonomic centers, that is, the medial nuclei of the hypothalamus in the diencephalon causes asymmetric per-rotational nystagmus (PRN) in healthy or sympathectomized rabbits. The superior cervical ganglion was removed on one or both sides. Asymmetric PRN occurred very rarely in normal or bilaterally sympathoectomized animals, while directional preponderance (DP) appeared in more than half of the recordings in unilaterally sympathectomized animals. Although the rise in blood pressure (BP) during the intravenous influsion of norepinephrine in unilaterally sympathectomized animals also caused significant DP (previous paper), it was less than the degree of DP appearing with the same increment of BP caused by hypothalamic stimulation. Three of 5 animals with asymmetric PRN caused by stimulation showed side differences of cerebellar oxygen tension.These findings show that asymmetric PRN following hypothalamic stimulation can be explained by a neural action on the vestibular neurons from the hypothalamus via the brainstem reticular formation or the cerebellum in addition to the asymmetric vertebral blood flow induced by symathetic vasoconstriction. We propose that this experimental model shows how psychogenic vertigo and/or dizziness can originate from distrubances of the central autonomic nervous system.

著者

簑和田 寛子

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.62, no.6, pp.735-798, 1969-06-01 (Released:2011-10-14)

参考文献数

517

被引用文献数

2

著者

荻野 敏 入船 盛弘 後藤 啓恵 仙波 治 野入 輝久

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.92, no.3, pp.309-324, 1999-03-01

参考文献数

13

被引用文献数

4

---

The clinical efficacy and safety of 200 &mu;g/day (100&mu;g b. i. d) of mometasone furoate nasal spray (MFNS) administered for 2 weeks was evaluated by comparison with a low dose of MFNS of 50&mu;g/day (50&mu;g o. d.) using the envelope-method in a total of 65 patients with Japanese cedar<br>pollenosis.<br>The pollen counts for Japanese cedar in 1995 were extremely high in the Kansai district. About 5, 000 counts/cmz was confirmed in and around Osaka.<br>In the analysis of final overall improvement, marked or moderate improvement was observed in 76.2% (16/21) and 20.8% (5/24) of patients receiving MFNS 200&mu;g/day and 50&mu;g/day, respectively. The difference in efficacy between the two dosage groups was confirmed independently of timing of the initiation of administration. In the analysis of overall safety, high safety was observed with both treatments. The above results suggest that 200&mu;g/day of MFNS can be considered the recommended dose for the treatment of Japanese cedar pollenosis.

著者

庄司 和彦 藤田 修治 大森 孝一 辻 純 伊藤 壽一 本庄 巖

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.81, no.12, pp.1709-1713, 1988-12-01 (Released:2011-11-04)

参考文献数

4

被引用文献数

1 1

---

Patients with multi-electrode cochlear implants can distinguish vowels well, but the ‘sounds’ they hear through this device are unknown. In order to simulate vowels through multielectrode cochlear implants, we synthesized waves which have translated formant frequencies using a computer and reverse fourier transformation .Through a digital-analog converter, we heard the synthesized sounds. Each sound is quite different from each vowel, but we can easily distinguish them from each other. With the use of this procedure, cochlear implants can be expected to be improved.

著者

田島 正記 武藤 二郎 滋賀 秀壮 目澤 良憲

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.88, no.12, pp.1571-1578, 1995-12-01

参考文献数

34

---

Prolonged vertigo and dizziness are good indications for Kampo treatment. An analytical study of the effect of Kampo-medicines on 30 patients with prolonged vertigo or dizziness was carried out, and the following results were obtained:<br>1) Every male patient was successfully cured with &ldquo;Sui&rdquo; medicine*.<br>2) Female patients more than about 70 years of age were also cured with &ldquo;Sui&rdquo; medicine.<br>3) Female patients with menstrual disorders, or uterine and ovarian diseases were cured with a combination of &ldquo;Sui&rdquo; and &ldquo;Ketsu&rdquo; medicine**.<br>4) Younger females with vertigo or dizziness at the time of menstruation were treated succesfully with &ldquo;Ketsu&rdquo; medicine only.<br>5) Patients wtih psychosomatic symptoms in addition to vertigo or dizziness required &ldquo;Ki&rdquo; medicine*** in combination with &ldquo;Sui&rdquo; or &ldquo;Ketsu&rdquo; medicine.<br>These results have contributed to finding the most effective Kampo-medicine for patients suffering from prolonged vertigo and/or dizziness.<br>*&ldquo;Sui&rdquo; medicine: medicine for regulating body fluids.<br>**&ldquo;Ketsu&rdquo; medicine: medicine for regulating blood and the water metabolism of the body.<br>***&ldquo;Ki&rdquo; medicine: medicine for regulating vital energy in the body.

著者

鈴木 安恒 渡邊 すみえ

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.36, no.7, pp.601-603, 1941

著者

北原 糺 久保 武

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.97, no.12, pp.1029-1039, 2004-12-01 (Released:2011-10-07)

参考文献数

55

---

Transient receptor potential cation channel subfamily V (TRPV) is a non-specific cation ion channel receptor family with six transmembrane domains. At first, TRPV1 was cloned in 1997 as a nociceptive receptor sensitive to capsaicin, an essence of hot chili pepper. So far, it has been revealed to be responsive to various kinds of nociceptive stimuli such as, heat, proton ion, low extracellular osmolarity and so on. That's why we, neuro-otologists, are quite interested in roles of this family in the inner ear. It might be possible that TRPV family in the inner ear is involved in the mechanism of caloric-induced nystagmus, the way of bicarbonate action against vertigo and the pathogenesis of endolymphatic hydrops syndrome including Meniere's disease. Here, we would like to review recent findings about TRPV family together with our data and suggest new insights for breaking through unsolved questions in neuro-otology.

著者

林 裕史 新正 由紀子 朝戸 裕貴 加我 君孝

出版者

The Society of Practical Otolaryngology

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.103, no.10, pp.903-907, 2010 (Released:2010-10-01)

参考文献数

4

---

In treating congenital microtia and atresia, we conduct simultaneous external canal plasty, tympanoplasty, and auricle elevation with plastic surgeons about 6 months after auricleplasty by only plastic surgeons. The results are good both cosmetically and functionally. We report 13 cases in which hearing did not improve satisfactorily after surgery using postoperative high-resolution computed tomography (HRCT) of the temporal bone. Lateral healing was seen in 9 (69%), new bone proliferation in 3 (23%), malpositioning of a cartilage block in 2 (15%), and both lateral healing and malpositioning of a cartilage block in 1 (7.6%).

著者

比嘉 輝之 我那覇 章 近藤 俊輔 親川 仁貴 安慶名 信也 平川 仁 鈴木 幹男

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.114, no.12, pp.909-916, 2021

---

<p>Cochlear implant surgery has been introduced successfully and is now one of the commonly performed surgeries. However, the surgical strategy of cochlear implantation in patients with chronic middle ear diseases, such as chronic otitis media and cholesteatoma, has not yet been fully established. In the present report, we describe the surgical technique adopted and prognosis of two patients with severe adhesive otitis media who underwent cochlear implant surgeries. Both underwent one-stage cochlear implantation combined with external auditory canal closure (blind-sac closure). Mastoidectomy with removal of the whole canal wall was performed to remove the otitis lesion thoroughly, and external auditory canal wall closure was performed to prevent recurrence of the lesion. A pneumatized tympanic cavity was observed and canal wall closure was maintained in both cases. Both patients acquired fair hearing ability with the cochlear implants. No severe complications have occurred until now, four years since the cochlear implantation. Although external ear canal closure destroys the natural structure of the external ear, one-stage cochlear implant surgery combined with canal closure is useful for elderly patients with systemic complications who desire shortening of hearing-deprived period.</p>

著者

伊藤 明和 柳田 則之 鈴木 康之 鈴木 浩二 坂堂 正生 田中 八郎 吉田 充治 三宅 弘 丹羽 英人 加藤 通郎

出版者

The Society of Practical Otolaryngology

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.72, no.11, pp.1539-1551_2, 1979

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1. 臨床的に鼻アレルギーと診断された120症例中脱落26例を除いた94症例について, Gamma globulin を Placebo としてHGの二重盲検法による治験を行い, 著効5症例, 有効18症例, やや有効13症例, 無効11症例の成績を得た. やや有効を有効例に含めた有効率は76.6%, やや有効を無効例に含めた有効率は48.9%で, いずれの場合も Placebo 群の有効率を上回った.<br>2. 鼻症状の改善では, 鼻閉の改善においては有意差が認められなかったが, くしゃみ, 鼻汁の改善および総合鼻症状改善度では有意差が認められた.<br>3. 鼻粘膜所見の改善では, 分泌物の量については有意な改善が認められなかったが, 下甲介腫脹, 色調および総合鼻粘膜所見改善度については有意差が認められた.<br>4. 総合改善度については, 推計学的に明白な有意差が認められた.<br>5. 皮内反応, 誘発反応, 鼻汁中好酸球では両群間の成績に明らかな差はないが, ヒスタミン反応では, H群に有意な改善が認められる.<br>6. 副作用は全例に認められなかった.<br>7. これらの成績からして, 鼻アレルギーに対してHGは十分使用に値する薬剤であると考える.

著者

吉本 裕

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.63, no.7, pp.665-675, 1970-07-01 (Released:2011-10-14)

参考文献数

13

著者

岩塚 和子

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.98, no.6, pp.447-452, 2005-06-01

参考文献数

11

被引用文献数

3 1

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A 31-year old woman with Churg-Strauss Syndrome (CSS) including eosinophilic otitis media is presented. Other manifestations included an 11-year history of nasal allergy followed by bronchial asthma, sinusitis with nasal polyps, eosinophilic pneumonia accompanied by peripheral eosinophilia (34% of 6, 600/&mu;l leukocytes), and erythema in both legs. Repeated episodes of painless right otitis media occurred without fever during the first stage of CSS characterized by an allergic state. This progressed to bilateral otitis media with gelatinous mucoid fluid accumulations shortly before the second stage of CSS characterized additionally by peripheral eosinophilia and eosinophilic pneumonia. Numerous eosinophils were found in gelatinous fluid within the tympanic cavity.<br>The patient was diagnosed with bilateral eosinophilic otitis media, which was controlled by nebulizer therapy with 2% fosfomycin and 0.2% betamethasone solution directed into the Eustachian tube and tympanic cavity. Hearing loss and vertigo have been avoided. This case strongly suggests that eosinophilic otitis media can be a manifestation of CSS.

著者

間島 雄一 坂倉 康夫 浜口 富美 村井 須美子

出版者

耳鼻咽喉科臨床学会

雑誌

耳鼻咽喉科臨床 (ISSN:00326313)

巻号頁・発行日

vol.85, no.8, pp.1333-1340, 1992-08-01 (Released:2011-11-04)

参考文献数

13

被引用文献数

5 8

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This study was desiged to determine the effectiveness of Tsumura Shin'i-seihai-to (TJ-104), a Kampo medicine, in chronic sinusitis. The subjects of this study were 30 patients aged 19 to 80 years, who received TJ-104 7.5g p. o. per day for four weeks.The general effectiveness of TJ-104 On subjective symptoms and rhinoscopic observations was 69.0%.Nasal mucociliary clearance (ST) was determined by the saccharin method in 28 subjects before (week 0) and four weeks after the start of the administration (week 4). At week 0, ST was within the normal range in 15 patients, and was retarded in 13 patients. At week 4, ST was signiflcantly better than at week 0 in those patients whose ST was retarded before treatment (p<;0.001). No significant difference was observed in either the elasticity (G') or the viscosity (η') of nasal mucus between week 0 and week 4.It was concluded that 1) TJ-104 can improve reduced nasal mucociliary clearance, 2) TJ-104 has no effect on reducing the viscoelasticity of the nasal mucus, and 3) TJ-104 is considered to be a useful drug for the conservative treatment of chronic sinusitis.