著者

横田 康成 河村 洋子 亀谷 謙

出版者

社団法人日本生体医工学会

雑誌

生体医工学 : 日本エム・イー学会誌 (ISSN:1347443X)

巻号頁・発行日

vol.44, no.2, 2006-06-10

著者

柴田 聡 渡邉 高志 アリフィン アマハド 吉澤 誠 星宮 望

出版者

社団法人日本生体医工学会

雑誌

生体医工学 : 日本エム・イー学会誌 (ISSN:1347443X)

巻号頁・発行日

vol.44, no.4, pp.687-695, 2006-12-10

被引用文献数

3

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ataOur previous computer simulation study showed that the fuzzy controller based on cycle-to-cycle control would be useful in controlling the swing phase of hemiplegic gate using functional electrical stimulation (FES). However, a simplified musculoskeletal model of a swing leg with the floor reaction force eliminated was used in the previous study. In this paper, a musculoskeletal model consisting of the stance and swing legs with a floor model was developed first. Then, the fuzzy controller for controlling the swing phase was examined using computer simulation of the developed model including the toe off and initial contact. Computer simulation results showed that the fuzzy controller and the stimulation schedule developed in our previous work were adequate, and that modifying the schedule considering the strength of the plantar flexion of the ankle joint would be more effective for improving responses at an early stage of control. A control method based on using electromyograms (EMGs)was also discussed. The fuzzy controller and a previously created EMG-based stimulation schedule, which was unable to control the swing phase, were modified by changing the role of the rectus femoris muscle. The modified fuzzy controller with a new EMG-based stimulation schedule was found to develop the swing phase movement appropriately.

著者

白川 修一郎

出版者

社団法人日本生体医工学会

雑誌

生体医工学 : 日本エム・イー学会誌 (ISSN:1347443X)

巻号頁・発行日

vol.46, no.2, pp.160-168, 2008-04-10

被引用文献数

3

著者

松井 宏行 中島 一樹 佐々木 和男

出版者

社団法人日本生体医工学会

雑誌

生体医工学 : 日本エム・イー学会誌 (ISSN:1347443X)

巻号頁・発行日

vol.46, no.1, pp.117-125, 2008-02-10

被引用文献数

8

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In an aging society, an increase is seen in the number of elderly person living alone. As the incidence of disease and injury increases with aging, a family who lives apart from an elderly parent may be concerned about that person's safety. Conversely, an aging parent may be interested in the lives of their children who live apart from them. To improve the relationship between family members who share such a situation, we have developed an inexpensive telemonitoring system using the television's operating state (TVOS). The system is comprised of sensor and communication sections. The sensor section consists of a current sensor for a television (TV) and an infrared sensor for a remote controller (RC), and outputs the TVOS, i.e., outputs indicating whether the TV is on or off and the RC is used. The communication section consists of a set of power-line communications modems and a computer with an Internet connection. We installed such a system in both an elderly person's home and that of his family living at a distant location. The computer at the family's end requires the TVOS data from the computer at the elderly person's end to be transmitted via the Internet once per minute. A feasibility test, conducted over one year, was performed in two pairs of parent-child families, four families, living apart. The results showed that (1) differences in the TVOS pattern was obtained by each family, and (2) the TVOS pattern differed between business days and non-business days in the same family. The present system does not specifically describe the health condition of an elderly parent living alone, but if that individual's family is familiar with the parent's viewing habits, they would be able to identify any change that might indicate a need for assistance.

著者

山越 康弘 小川 充洋 山越 健弘 田村 俊世 山越 憲一

出版者

社団法人日本生体医工学会

雑誌

生体医工学 : 日本エム・イー学会誌 (ISSN:1347443X)

巻号頁・発行日

vol.46, no.1, pp.49-57, 2008-02-10

参考文献数

27

被引用文献数

3

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金沢大学大学院自然科学研究科An optical method recently proposed for non-invasive in vivo blood glucose concentration (BGL) measurement, named "Pulse Glucometry", was combined and compared with four multivariate analyses for constructing calibration models: Principal Component Regression (PCR), Partial Least Squares Regression (PLS), Artificial Neural Network (ANN), Support Vector Machines Regression (SVMsR). A very fast spectrophotometer for "Pulse Glucometry" provides the total transmitted radiation spectrum (I_λ) and the cardiac-related pulsatile component (ΔI_λ) superimposed on I_λ in human fingertips over a wavelength range from 900 to 1700 nm with resolution of 8 nm in 100 Hz sampling. From a family of I_λs measured, which include information relating to blood constituent such as BGL values, differential optical densities (ΔOD_λs, where ΔOD_λ=Log(1+ΔI_λ/I_λ)) were obtained and normalized by the ΔOD_λ values at 1100 nm. Finally, the 2nd derivatives of the normalized ΔOD_λs(Δ^2OD_λs) along wavelengths were calculated as regressors. Subsequently, calibration models from paired data sets of regressors(the values of Δ^2OD_λs) and regressand (the corresponding known BGL values) were constructed with PCR, PLS, ANN and SVMsR. The results show that each calibration model provides a relatively good regression with a modified 5-fold cross validation for total 95 paired data, in which the BGLs ranged from 100.7-246.3 mg/dl. The results were evaluated by the Clarke error grid analysis and all data points obtained from all calibration models fell within the clinically acceptable regions (region A or B). Among them, ANN and SVMsR calibration provided the best plot distributions (in ANN; Region A: 77 plots (81.1%), B: 18 plots (18.9%). in SVMsR; Region A: 78 (82.1%), B: 17 (17.9%)). Total calculation time of SVMsR is about 100 times shorter than ANN. These results suggest that a calibration model using SVMsR is highly promising for "Pulse Glucometry.

著者

森下 竜一

出版者

社団法人日本生体医工学会

雑誌

生体医工学 : 日本エム・イー学会誌 (ISSN:1347443X)

巻号頁・発行日

vol.46, no.3, pp.325-327, 2008-06-10

著者

山口 昌樹 花輪 尚子 吉田 博

出版者

社団法人日本生体医工学会

雑誌

生体医工学 : 日本エム・イー学会誌 (ISSN:1347443X)

巻号頁・発行日

vol.45, no.2, pp.161-168, 2007-06-10

参考文献数

26

被引用文献数

28

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In order to realize a novel handheld monitor for the sympathetic nervous system, we fabricated an analytical system for salivary amylase activity (sAMY) using a dry-chemistry system called a"Cocoro Meter." The device to quantify sAMY using an activity rate method was completely automated. This method was made possible by the fabrication of a disposable test-strip equipped with built-in salivacollecting and reagent papers, and an automatic saliva transfer mechanism. Within a range of sAMY between 0-200 kU/l, the calibration curve for the monitor showed a coefficient of R^2=0.988 and CV (coefficient of variation) of 10.2%. The reproducibility between devices was within 10%. Moreover, it was demonstrated that : (i) the quantitativity of the sample collected by the test-strip was sufficient, (ii) the sublingual area was suitable as the sampling site of the saliva, and (iii) 30 s was sufficient for saliva sampling. Considering all of these effects including the saliva sampling site, a 12.1% CV was obtained for this monitor. A total of 1 min was sufficient to analyze the sAMY. Thus, this study demonstrated that the monitor might be used as a good index for psychological research.

著者

山下 和彦 野本 洋平 梅沢 淳 高野 千尋 太田 裕治 井野 秀一 伊福部 達 小山 裕徳 川澄 正史

出版者

社団法人日本生体医工学会

雑誌

生体医工学 : 日本エム・イー学会誌 (ISSN:1347443X)

巻号頁・発行日

vol.45, no.1, pp.121-128, 2007-03-10

被引用文献数

2

---

The aim of this study was to evaluate the postural control ability using stabilogram-diffusion analysis (SDA). Any parameters of SDA were compared with several parameters of body sway derived from recordings of the center of pressure (COP) with the aid of a static force platform. The subjects were 38 elderly healthy volunteers. They quietly stood on a static force plat form with open and closing eyes. As the results, there was a significant correlation between the diffusion constant derived from the parameters of SDA and the parameters of COP with eyes open and closed. The correlation was found to be greater in the closing eye condition than that in the open eye condition. The correlations between diffusion coefficients and the range and mean of anterior-posterior velocity were greater than the correlations between the diffusion coefficients and the range and mean of the lateral velocity. Thus, the muscle of the tibialis anterior and the planter muscles was suggested.

著者

岡田 志麻 藤原 義久 松浦 英文 安田 昌司 水貝 浩二郎 牧川 方昭 飯田 健夫

出版者

社団法人日本生体医工学会

雑誌

生体医工学 : 日本エム・イー学会誌 (ISSN:1347443X)

巻号頁・発行日

vol.41, no.4, pp.493-497, 2003-12-10

---

Sleep is very important to keep our physical condition healthy. Many studies have been devoted to clarify the mechanism of sleep and to monitor the sleep all night. In this study, we paid attention to heart activity during sleep and have developed a nonrestraint monitoring method of heart activity using an acceleration sensor set inside the coverlet. This method is easy for the use of sleep monitoring at home in daily life. An acceleration sensor was set inside the coverlet as it opposing to subject's left chest. Subjects were asked to lie in supine position and the coverlet with an acceleration sensor was put on the subject. Mechanical vibration from heart activity expected to be carried to the acceleration sensor through the coverlet. As a result, periodic vibration was measured successfully and this vibration was proved to be in high correlation with the R wave of ECG in six subjects. The same results were obtained even in case of lying in right and left lateral decubitus position.

著者

藤原 義久 冷水 一也 源野 広和 松浦 英文 安田 昌司 飯田 健夫 牧川 方昭

出版者

社団法人日本生体医工学会

雑誌

生体医工学 : 日本エム・イー学会誌 (ISSN:1347443X)

巻号頁・発行日

vol.43, no.1, pp.162-171, 2005-03-10

参考文献数

20

被引用文献数

2

---

This paper describes the development of a sensor incorporating an algorithm that estimates the quality of comfortableness by measuring peripheral skin temperature, pulse, and galvanic skin response (GSR) that reflect autonomic nervous system activity. A correct answer rate of 83% was obtained between the subjective comfortableness and the estimated comfortableness by the developed sensor. For the application of this human feeling sensor, we used it to estimated the comfortableness of subjects receiving massages, then developed two alternative adaptive massage control procedures based on the sensor's estimate, and verified the effectiveness of the results through testing the subjects. We observed that in course A (dynamic comfortableness) the peripheral skin temperature dropped and the GSR and pulse rate increased, while in course B (static comfortableness) the peripheral skin temperature rose and the GSR and pulse rate dropped. By the end of the control sequence, there was a statistically significant difference in the amounts of change in both the peripheral skin temperature and the GSR between the two sequences (p<0.05). To examine the effects of each course more closely, we mapped the trajectories of physiological change during the control sequences of each course at twentysecond intervals, and the results correlated closely with the subjective assessments. These results suggest that bio-control adapted to comfortableness is feasible.

著者

山田 憲嗣

出版者

社団法人日本生体医工学会

雑誌

生体医工学 : 日本エム・イー学会誌 (ISSN:1347443X)

巻号頁・発行日

vol.46, no.5, pp.540-541, 2008-10-10

著者

千葉 淳 仙道 雅彦 石山 和志 荒井 賢一

出版者

社団法人日本生体医工学会

雑誌

生体医工学 : 日本エム・イー学会誌 (ISSN:1347443X)

巻号頁・発行日

vol.42, no.4, pp.313-317, 2004-12-10

被引用文献数

1

---

In this paper, the authors propose applying a magnetic actuator to a capsule endoscope. We fabricated a capsule-type magnetic actuator and investigated its moving properties in a silicone tube and in pig intestines. The device consists of a dummy capsule measuring 11 mm in diameter and 40 mm in length, a magnetic actuator composed of a permanent magnet inside the dummy capsule and a 1-mmφ spiral structure outside the capsule. The permanent magnet is magnetized in the direction of the diameter. When a rotational magnetic field is applied, the magnetic actuator rotates and moves wirelessly. In this study, we measured the effect of the spiral shape on the velocity and thrust properties. According to our experimental results using the silicone tube, the optimal actuator was formed with 4 spirals set at a spiral angle of 45 degrees. In the subsequent moving test performed in pig intestines, the actuator traveled a distance of 450 mm to its destination in the large intestine in 150 s, and a distance of 400 mm to its destination in the small intestine in 110s. This result confirms the potential applicability of the actuator as a guidance system for capsule endoscopes.

著者

大西 優貴 川北 悠介 山崎 健一 藤里 俊哉 宇戸 禎仁

出版者

社団法人日本生体医工学会

雑誌

生体医工学 : 日本エム・イー学会誌 (ISSN:1347443X)

巻号頁・発行日

vol.46, no.1, pp.64-68, 2008-02-10

被引用文献数

2

---

For application of a cultured muscle to medical engineering, both to control C2C12 myoblast differentiation and to investigate a contraction mechanism of C2C12 myotube are important. The muscle can be derived from a cultured C2C12 myoblast in an incubator. It is important to evaluate a level of C2C12 differentiation quantitatively. In this study, we propose an efficient evaluation method by cellular membrane potential measurement instead of the conventional methods that take time and are higher cost.

著者

田中 慶太 川勝 真喜 根本 幾

出版者

社団法人日本生体医工学会

雑誌

生体医工学 : 日本エム・イー学会誌 (ISSN:1347443X)

巻号頁・発行日

vol.44, no.4, pp.551-559, 2006-12-10

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Magnetoencephalography (MEG) was recorded under attend and ignore conditions to detect auditory steady-state responses (ASSR) to stimuli regularly repeated 40 times/s for 2 s, and synchronization of its 40-Hz component was measured using phase coherence. The major finding of the experiment was that the increased ASSR obtained by averaging in the attend condition was due to the increased degree of synchronization as the result of stimulation during the 40-Hz activity rather than the increase in power. We made a simple differential equation model for phase dynamics and compared the change of phase coherence calculated from the model with that obtained from the measurement. The model predicted the behavior of experimental phase coherence quite well, and the estimated value of one of the two parameters in the model representing the effect of stimulus on the phase was significantly larger for the attend condition than for the ignore condition, suggesting the validity of the model.

著者

鈴木 恭宜 大下 浩二郎 垂澤 芳明 野島 俊雄 豊島 健 藤本 裕

出版者

社団法人日本生体医工学会

雑誌

生体医工学 : 日本エム・イー学会誌 (ISSN:1347443X)

巻号頁・発行日

vol.46, no.2, pp.189-201, 2008-04-10

参考文献数

23

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This paper presents a probabilistic evaluation of electromagnetic interference caused by portable telephones in implantable cardiac pacemakers. Based on experimental results of electromagnetic interference in the 900 MHz and 1.5 GHz band PDC(Personal Digital Cellular) system in Japan, a distribution is extracted of the maximum distances between the affected pacemaker and a portable telephone. This paper shows that the distribution is approximated as a Rayleigh distribution using statistical analysis. The interfering probability for which the maximum distance of X cm is exceeded is defined based on the product of the cumulative distribution of the Rayleigh distribution and the ratio of the affected pacemaker types to the measured ones. The interfering probabilities that exceeded the maximum distance of 15 cm for the 900 MHz and 1.5 GHz band portable telephones are 5.0×10^<-4> and 6.0×10^<-4>, respectively. The expected values, which are a product of the interfering probability and the number of measured pacemaker types for the 900 MHz and 1.5 GHz band portable telephones, are 0.210 and 0.248, respectively. The continued surge in the number of pacemaker types indicates that the expected values will continue to increase. If the immunity of the new pacemaker types in the future maintains the same level as that in the present, this paper indicates that the maximum distance of the new pacemaker types must continue to be confirmed using the electromagnetic interference test.

著者

小宮 正快

出版者

社団法人日本生体医工学会

雑誌

生体医工学 : 日本エム・イー学会誌 (ISSN:1347443X)

巻号頁・発行日

vol.44, no.2, 2006-06-10

著者

佐藤 知子 小岩 研 佐川 貢一

出版者

社団法人日本生体医工学会

雑誌

生体医工学 : 日本エム・イー学会誌 (ISSN:1347443X)

巻号頁・発行日

vol.44, no.2, 2006-06-10

著者

秋元 俊成 寺田 信幸 松元 明弘

出版者

社団法人日本生体医工学会

雑誌

生体医工学 : 日本エム・イー学会誌 (ISSN:1347443X)

巻号頁・発行日

vol.46, no.1, pp.58-63, 2008-02-10

被引用文献数

1

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We're developing walking robot with the object of bringing the walking of robot close to that of human utilizing pendular motion of legs. First, human gait analysis has been conducted in the study. In particular, we measured joint angle variation and myoelectric signal at a normal walking pace, focusing on the ankle mobility. From the result of the measurement, we realized that ankle mobility of supporting leg not only provides energy in the direction of travel by kicking back but also leads idling leg to swing forward. Then, we conducted modeling of ankle-driven walking and reproduced the motion using highly simplified model. As the result, walking driven only by ankle was realized in simulation. Therefore, it is expected that the system could not only be used for walking robot but also be applied to walking aids or artificial legs, because it reproduces a walking utilizing pendular motion of legs effectively due to the hip of free joint, and it is possible to reduce the number of actuators.

著者

加藤 陽子 姫野 龍太郎

出版者

社団法人日本生体医工学会

雑誌

生体医工学 : 日本エム・イー学会誌 (ISSN:1347443X)

巻号頁・発行日

vol.41, no.2, pp.115-121, 2003-06-10

被引用文献数

2

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MRI angiography is useful for the diagnosis of blood vessels and blood flow. The phase contrast method is suitable for quantitatively evaluating blood flow velocity because it is reflected in the phase. However, the velocity is low near the vessel wall, and the effect of the dephasing cannot be ignored in this region. On the other hand, the vessel wall is static and the effect of dephasing could be weak. The maximum velocity in the blood vessel also seems to be an accurate parameter because of the weak effect of dephasing. The static and maximum velocity regions therefore seem helpful for extraction of the vessel region, although the influence of the relaxation times and sequence parameters on dephasing have not yet been clarified. In this study we investigate the effects of these parameters on the measurement accuracy of the velocity and design a simple method for the regional extraction of blood vessels. The relaxation times, T_R, T_E and VENC, influenced the accuracy of velocity measurement. Although no dominant parameter was found among them, several combinations of parameters resulted in a significant difference in accuracy. The standard deviation of the phase in the static region increased with increasing relaxation time. We also extracted the popliteal artery region by growing the region until the phase reached a threshold value. This threshold value was set based on the standard deviation of the area in a static region. This method was found to be suitable for extracting the blood vessels from MR images obtained when using the phase contrast method.