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1 0 0 0 OA 小嶋壽の臨床の玉手箱何か変だな, クラウンセット? (8)

著者: 小嶋壽
出版者: 特定非営利活動法人日本顎咬合学会
雑誌: 日本顎咬合学会誌咬み合わせの科学 (ISSN:13468111)
巻号頁・発行日: vol.24, no.2-3, pp.374-377, 2004-11-05 (Released:2010-09-09)

2017-12-16 07:36:22
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1 0 0 0 OA 広庶物類纂

出版者: 写

2017-12-16 07:23:06
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1 0 0 0 OA Physical exercise and renal function

著者: Masato Suzuki
出版者: The Japanese Society of Physical Fitness and Sports Medicine
雑誌: The Journal of Physical Fitness and Sports Medicine (ISSN:21868131)
巻号頁・発行日: vol.4, no.1, pp.17-29, 2015-03-25 (Released:2015-03-23)
参考文献数: 51
被引用文献数: 1 8

The kidneys play an important role in regulating acid-base and water-electrolyte balance disturbances induced by exercise. In sports medicine, research on renal function during exercise in healthy individuals and athletes is less common than other areas of study such as the respiratory, circulatory, and neuromuscular systems as well as metabolism, since renal function has no direct effect on athletic performance. In this study, we reviewed previous research results obtained in our laboratory and other studies as follows: 1) effects of exercise intensity on renal plasma flow and glomerular filtration rate; 2) effects of exercise intensity on plasma hormone responses and urinary excretion of water and electrolytes; 3) effects of aging on renal function following exhaustive exercise; 4) mechanisms underlying exercise-induced diuresis in healthy volunteers; 5) mechanisms underlying exercise-induced proteinuria (EIP) in healthy volunteers; and 6) effects of exercise combined with angiotensin-converting enzyme (ACE) inhibitor (ACE-I) on the progression of diabetic nephropathy (DN) in obese diabetic model rats. The number of obese diabetes patients is increasing in advanced countries, and the number of hemodialysis (HD) patients per capita in Japan is the highest worldwide. Approximately 42% of patients with DN undergo HD treatment every year. However, regular exercise has not been positively recommended for patients with nephropathy despite being an essential clinical approach for patients with diabetes. Moreover, the ideal exercise regimen for patients with diabetes complicated by nephropathy has not been investigated much. Therefore, a future study should investigate exercise therapy for patients with DN.

2017-12-16 06:28:45
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1 0 0 0 OA 紀効新書定本 9巻

著者: 相馬, 九方
出版者: 秋田屋善助[ほか8名]
巻号頁・発行日: vol.[3], 1856

2017-12-16 06:23:07
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1 0 0 0 イトラコナゾール内用液と飲料(オレンジジュース)の同時服薬によるアドヒアランス向上への試み

著者: 足立陽子角熊俊也鏡亮吾西尾晃赤坂浩司常峰紘子小高泰一平松靖史多田寛
出版者: 一般社団法人日本血液学会
雑誌: 臨床血液
巻号頁・発行日: vol.51, no.5, pp.315-319, 2010

抗真菌薬“イトラコナゾール内用液”は,造血器悪性腫瘍患者に対して真菌感染症予防を目的に投与されるなど,その有用性が知られている。一方で,同薬には固有の苦味があり,服薬困難となってアドヒアランス低下につながるケースが散見されていた。そこで,今回われわれは,同薬をオレンジジュースと一緒に服薬する方法(オレンジジュース群)を考案し,薬剤吸収(血中濃度)および飲みやすさ(5段階味覚評価)への影響を検討した。その結果,水で服薬した場合(対照群)と比べて,オレンジジュース群の血中濃度に差異は無く,飲みやすさで改善が認められた。本法は臨床現場で簡便かつ安全に実施でき,服薬アドヒアランスの向上に期待できるものと考えられた。