著者

J.A.フィシュマン著 湯川恭敏訳

出版者

大修館書店

巻号頁・発行日

1974

著者

デュンダル メルトハン 三沢 伸生 / ミサワ ノブオ Merthan.A DUNDAR Nobuo MISAWA

出版者

東洋大学社会学部

雑誌

東洋大学社会学部紀要 = The Bulletin of Faculty of Sociology,Toyo University (ISSN:04959892)

巻号頁・発行日

vol.46, no.2, pp.181-220, 2009-03

著者

Dundar Merthan A. 三沢 伸生 / ミサワ ノブオ Merthan.A DUNDAR Nobuo MISAWA

出版者

東洋大学社会学部

雑誌

東洋大学社会学部紀要 (ISSN:04959892)

巻号頁・発行日

vol.46, no.2, pp.181-220[含 英語文要旨], 2009-03

著者

P.J. VELASCO J.R. WHITAKER A. CHEN J.R. HITAKER

出版者

日本食品保蔵科学会

雑誌

食品と低温 (ISSN:02851385)

巻号頁・発行日

vol.8, no.2-3, pp.85-92, 1982-09-25 (Released:2011-05-20)

参考文献数

31

被引用文献数

1

---

ブランチングは野菜凍結の重要な前処理工程となっているが, これについての基礎的知識はまだ十分でないように思われる。今回これに関する次の3つの資料を訳出紹介する。(1) パーオキシダーゼ-その熱変性と再生について-(2) 食品中のカタラーゼ(3) 野菜ブランチングの必要性アメリカ冷凍食品協会 (AFFI) では, カリフォルニア大学デイビス分校 (U.C.D.) のJ.WHITAKER博士らに, 1980年9月来野菜のブランチングについて研究を委託している。その目的は, この問題に関与する酵素系についての知識を深め, 不活性化にもっとも適した方法を開発し, また酵素再活性化の重要さを知ることにあるという。ここに訳出した資料中, (1) および (2) は上記プロジェクトの一環としてAFFIに提出された報告である。また (3) は, 野菜のノーブランチング凍結について, かつてQ.F.F.誌上に解説されたもので, 興味ある関係資料として併せて要点を訳出したものである。大方の参考になれば幸いである。

著者

Barrios Arroyave A. Freddy Rodríguez Velásquez O. Javier Prieto Bohórquez E. Signed Grisales E. Carlos Correa Herrera C. Sandra Jattin Balcázar J. Jairo Soracipa Muñoz Ribka Ruiz Morales J. Jhon

出版者

The Japanese Society of Strategies for Cancer Research and Therapy

雑誌

Annals of Cancer Research and Therapy (ISSN:13446835)

巻号頁・発行日

vol.31, no.1, pp.7-12, 2023-02-14 (Released:2023-02-14)

参考文献数

26

---

Introduction: fractal geometry has been implemented to study natures’ irregular objects with diverse applications in medicine, from characterizations of human structures such as the division of bronchial or arterial trees to the diagnosis of abnormal cells, as it has been evidenced in the study of neoplasms. In this investigation, a characterization of the degree of irregularity of histologic samples of normal and thyroid gland neoplasms was developed in the context of fractal and Euclidean geometry.Methods: photographs of normal and neoplastic thyroid histologic samples obtained as surgical pieces were processed by a software that allows to delimit the borders of cellular structures. Then, grids of 5 and 10 pixels were superimposed over the images in order to measure their surfaces and occupation spaces through the Box-Counting method.Results: For nucleus measures values between 14 to 34 in the 5 pixels grid and values between 7 to 16 in the 10 pixels grid suggest normality.Conclusions: The surface of the nucleus and the cytoplasm measured by grids of 5 and 10 pixels, allow to carry out a more objective characterizations of both normal and abnormal thyroid cells.

著者

Hon-Kan Yip Pei-wen Wang Li-Teh Chang Ali A. Youssef Jiunn-Jye Sheu Fan-Yen Lee Chiung-Jen Wu

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

vol.71, no.8, pp.1213-1218, 2007 (Released:2007-07-25)

参考文献数

43

被引用文献数

8 9

---

Background Cytotoxic T lymphocyte antigen 4 (CTLA-4) is a particularly important molecule in down-regulating T-cell expansion and cytokine production. The purpose of the present study was to determine the frequency distribution of an A/G single nucleotide polymorphism at position 49 in exon 1 of the CTLA-4 gene, which may be a functional related-genetic risk marker for the development of ST-segment elevation (ST-se) acute myocardial infarction (AMI). Methods and Results A total of 503 consecutive patients, consisting of 250 ST-se AMI patients undergoing primary coronary angioplasty (group 1), 203 angina pectoris patients undergoing elective coronary angioplasty (group 2) and 50 patients with chest pain and normal coronary angiographic findings (group 3), were enrolled in the present study. The frequency of the G/G genotype was significantly higher in group 1 (53.2%) than in groups 2 (33.0%) and 3 (36.0%) (p=0.0005). In group 1, patients with a G/G genotype had significantly higher levels of high-sensitivity C-reactive protein and white blood cell counts, and much higher incidences of multi-vessel disease, greater lesion lengths, advanced congestive heart failure (≥ class 3) and 30-day mortality, than patients with G/A or A/A genotypes (p values<0.05 in all cases). Multivariate analysis of the enrolled baseline variables (age, gender, diabetes mellitus, smoking, hypertension and hypercholesterolemia) and the genotypes (G/G, A/G and A/A) demonstrated that G/G genotype is the only independent predictor of development of AMI (p<0.0001). Conclusion The G/G genotype polymorphism of the CTLA-4 gene is associated with increased risk of AMI. (Circ J 2007; 71: 1213 - 1218)

著者

W.A.シューハート著 W.E.デミング編 坂元平八監訳

出版者

岩波書店

巻号頁・発行日

1960

著者

Shoto Ikegami Dai Ishiyama Yoshiki Oda Kinuko Niihara Masafumi Yoshida Keiichi Honda Takashi A. Inoue Kagayaki Kuroda

出版者

Japanese Society for Magnetic Resonance in Medicine

雑誌

Magnetic Resonance in Medical Sciences (ISSN:13473182)

巻号頁・発行日

pp.bc.2022-0070, (Released:2023-02-08)

参考文献数

12

被引用文献数

1

---

Metamorphosis in the pupae of the Trypoxylus dichotomus was continuously observed at 9.4T until their emergence. A large liquid-like mass occupied most of the volume in the trunk, while the surrounding tissue already existed at the beginning of the observation period. As the mass shrunk, tissues such as flight muscle formed, whereas the reservoir became prolonged to form the intestinal tract. This implies that the liquid-like mass worked as the raw material for creating adult tissues.

著者

Rabab A. Husseini Naoko Abe Tomoaki Hara Hiroshi Abe Kentaro Kogure

出版者

The Pharmaceutical Society of Japan

雑誌

Biological and Pharmaceutical Bulletin (ISSN:09186158)

巻号頁・発行日

vol.46, no.2, pp.301-308, 2023-02-01 (Released:2023-02-01)

参考文献数

46

被引用文献数

3

---

mRNA vaccines have attracted considerable attention as a result of the 2019 coronavirus pandemic; however, challenges remain regarding use of mRNA vaccines, including insufficient delivery owing to the high molecular weights and high negative charges associated with mRNA. These characteristics of mRNA vaccines impair intracellular uptake and subsequent protein translation. In the current study, we prepared a minimal mRNA vaccine encoding a tumor associated antigen human gp10025–33 peptide (KVPRNQDWL), as a potential treatment for melanoma. Minimal mRNA vaccines have recently shown promise at improving the translational process, and can be prepared via a simple production method. Moreover, we previously reported the successful use of iontophoresis (IP) technology in the delivery of hydrophilic macromolecules into skin layers, as well as intracellular delivery of small interfering RNA (siRNA). We hypothesized that combining IP technology with a newly synthesized minimal mRNA vaccine can improve both transdermal and intracellular delivery of mRNA. Following IP-induced delivery of a mRNA vaccine, an immune response is elicited resulting in activation of skin resident immune cells. As expected, combining both technologies led to potent stimulation of the immune system, which was observed via potent tumor inhibition in mice bearing melanoma. Additionally, there was an elevation in mRNA expression levels of various cytokines, mainly interferon (IFN)-γ, as well as infiltration of cytotoxic CD8+ T cells in the tumor tissue, which are responsible for tumor clearance. This is the first report demonstrating the application of IP for delivery of a minimal mRNA vaccine as a potential melanoma therapeutic.

著者

B. A. Fenderson 山形 達也

出版者

FCCA(Forum: Carbohydrates Coming of Age)

雑誌

Trends in Glycoscience and Glycotechnology (ISSN:09157352)

巻号頁・発行日

vol.5, no.24, pp.271-285, 1993-07-02 (Released:2010-01-05)

参考文献数

76

被引用文献数

3 5

---

着床とは哺乳動物の初期胚が子宮壁に接着する発生上の複雑な過程である。ステロイドホルモンおよびサイトカインの影響下で非接着性の子宮上皮が接着性に変わることが重要である。子宮壁の接着性が変わる間に、子宮上皮の糖脂質や糖タンパク組成の変化、上皮表面の複合糖質分子の大きさや荷電の変化、内腔液に分泌される糖タンパク質のパターンの変化などを含む糖鎖の変化が沢山見られる。胚でも着床に先立って糖抗原の発現が大きく変わる。これらの発生特異的な変化が胚盤胞の子宮への接着の時間や場所を調節しているのかも知れない。着床に伴う糖鎖の役割について幾つかの検証しうる仮説が出されていて、糖鎖-タンパク質相互作用と、糖鎖-糖鎖間相互作用のどちらも有力である。

著者

GARCIA RODRIGUEZ Amaury A.

出版者

International Research Center for Japanese Studies

雑誌

Japan review : Journal of the International Research Center for Japanese Studies / SPECIAL ISSUE : Shunga: Sex and Humor in Japanese Art and Literature (ISSN:09150986)

巻号頁・発行日

vol.26, pp.137-149, 2013-01-01

---

In 1911 the journals and fierce enemy of censorship, Miyatake Gaikotsu 宮武外骨 (1867-1955), rescued some old references about the publication ban, in 1723, of a purportedly erotic sequel to the book Hyakunin joro shina sadame, by the famous Kyoto artist Nishikawa Sukenobu (1671-1750). Those references apparently turn this book into one of the first and rare examples of direct Edo period prohibition of sexually explicit material. Miyatake explores some other important cases in his Hikka shi 筆禍史. Yet, despite the many years that have passed since 1911, until now thisparticular episode has been dismissed, probably because of issues with credibility regarding Miyatake himself and the uncertainties about the existence of copies of the erotic book in question.

著者

Kent Elson S. Sorgon Rene A. Abesamis

出版者

The Japanese Coral Reef Society

雑誌

Galaxea, Journal of Coral Reef Studies (ISSN:18830838)

巻号頁・発行日

vol.25, no.1, pp.7-8, 2023 (Released:2022-10-19)

参考文献数

4

被引用文献数

1

著者

general editors S.A. Wurm and Shirô Hattori cartography Theo Baumann produced by the Australian Academy of the Humanities in collaboration with the Japan Academy and assisted by the Departments of Linguistics and of Human Geography the Research School of Pacific Studies the Australian National University

出版者

Australian Academy of the Humanities in collaboration with the Japan Academy

巻号頁・発行日

1981

著者

Sawada A. Koga T.

出版者

American Physical Society (APS)

雑誌

Physical review e (ISSN:24700045)

巻号頁・発行日

vol.95, no.2, pp.23309, 2017-02-21

被引用文献数

10

---

We have developed a method to calculate the weak localization and antilocalization corrections based on the real-space simulation, where we provide 147 885 predetermined return orbitals of quasi-two-dimensional electrons with up to 5000 scattering events that are repeatedly used. Our model subsumes that of Golub [L. E. Golub, Phys. Rev. B 71, 235310 (2005)] when the Rashba spin-orbit interaction (SOI) is assumed. Our computation is very simple, fast, and versatile, where the numerical results, obtained all at once, cover wide ranges of the magnetic field under various one-electron interactions H' exactly. Thus, it has straightforward extensibility to incorporate interactions other than the Rashba SOI, such as the linear and cubic Dresselhaus SOIs, Zeeman effect, and even interactions relevant to the valley and pseudo spin degrees of freedom, which should provide a unique tool to study new classes of materials like emerging 2D materials. Using our computation, we also demonstrate the robustness of a persistent spin helix state against the cubic Dresselhaus SOI.

著者

Fatimah Ibrahim Siti A. Ahmad Park Jong Woo Wan Abu Bakar Wan Abas

出版者

The Society of Physical Therapy Science

雑誌

Journal of Physical Therapy Science (ISSN:09155287)

巻号頁・発行日

vol.24, no.10, pp.1021-1024, 2012 (Released:2012-12-28)

参考文献数

22

被引用文献数

3 7

---

[Purpose] Salat is the prayer practiced by Muslims and it involves several physical motions, namely standing, bowing and prostrating, which can be considered as a form of slow moderate exercise. The purpose of this research was to investigate the activities of the upper body muscles and the body composition during Salat’s prostration and the child’s pose. [Subjects] Eight healthy male and female university students were recruited for this study. [Methods] The body composition of each subject was first measured. The subjects were then asked to perform Salat’s prostration motion followed by the child’s pose posture. Electromyographic (EMG) signals were recorded from the biceps brachii, triceps brachii, scapula muscle, and pectoralis major muscles. The signals were converted to root mean square values. The Mann-Whitney U non-parametric test was conducted to investigate the significance of differences in EMG mean values and body composition in both postures. [Results] The findings show that all the muscles were activated in both postures with the triceps brachii recording the highest value. For the triceps brachii, the prostration posture gave higher values. However, no significant difference was found in the body composition. [Conclusion] The prostration posture produces musculoskeletal effects similar to the child’s pose.

著者

Lisa A. Urry [ほか著] 池内昌彦 [ほか訳]

出版者

丸善出版

巻号頁・発行日

2018

著者

Ahmad H. Alghadir Sami A. Gabr Farag A. Aly

出版者

The Society of Physical Therapy Science

雑誌

Journal of Physical Therapy Science (ISSN:09155287)

巻号頁・発行日

vol.27, no.7, pp.2029-2033, 2015 (Released:2015-07-22)

参考文献数

69

被引用文献数

24 30

---

[Purpose] The purpose of this study was to evaluate the effect of 4 weeks moderate aerobic exercise on outcome measures of saliva stress hormones and lactate levels in healthy adult volunteers. [Subjects and Methods] Sixteen healthy students with an age range of 15–25 years participated in this study. The participants performed an exercise test of moderate intensity for 4 weeks, three times per week. The exercise was treadmill walking. Saliva concentrations of cortisol, testosterone and lactate dehydrogenase (LDH) were measured before and after the 4 weeks of moderate aerobic training using immunoassay techniques. [Results] After 4 weeks of exercise, there were significant increases in cortisol, free testosterone levels, and LDH activity along with a significant decrease in the ratios between testosterone and cortisol levels. No significant correlations were found among the studied parameters in the resting stage, a result which supports the positive effect of exercise on stress hormones following 4 weeks of training. [Conclusion] The results suggest that four weeks exercise of moderate intensity significantly affects the salivary stress hormones of young healthy volunteers. The data support the importance of salivary stress hormones as potential biological markers especially for older ages. However, more research is required to validate these biological markers which determine the host response to physical activity.

著者

A.シェーンベルク 著

出版者

音楽之友社

巻号頁・発行日

1968

著者

Prabir K. PATRA Edward J. DLUGOKENCKY James W. ELKINS Geoff S. DUTTON 遠嶋 康徳 笹川 基樹 伊藤 昭彦 Ray F. WEISS Manfredi MANIZZA Paul B. KRUMMEL Ronald G. PRINN Simon O'DOHERTY Daniele BIANCHI Cynthia NEVISON Efisio SOLAZZO Haeyoung LEE Sangwon JOO Eric A. KORT Suman MAITY 滝川 雅之

出版者

Meteorological Society of Japan

雑誌

気象集誌. 第2輯 (ISSN:00261165)

巻号頁・発行日

vol.100, no.2, pp.361-386, 2022 (Released:2022-04-13)

参考文献数

65

被引用文献数

8

---

大気中の一酸化二窒素(N2O)は地球温暖化および成層圏オゾン減少に影響を及ぼしており、発生源ごとの放出量推定の精緻化は気候変動の政策決定において非常に重要である。本研究ではまず大気大循環モデルMIROC4を基にした化学輸送モデル(ACTM)を用いたコントロール実験を行い、大気中N2O濃度の時空間変動について現場観測等を用いた検証を行なった。本計算に際しては各種起源(土壌起源、農業起源、その他人為起源、海洋起源)について複数のインベントリを用い、合計5種類の組み合わせで計算を行なった。その結果、N2Oの大気中寿命は年々変動の影響を含め、127.6±4.0年と推定された。次に、世界各地の42地点における1997年から2019年にかけての観測結果を用いて、世界を84分割した各地域におけるN2O放出量についてベイズ手法を用いた逆解法による推定を行なった。その結果、全球の陸域および海洋起源それぞれの放出量は2000年代には12.99±0.22 および 2.74±0.27 TgN yr-1、2010年代は14.30±0.20および 2.91±0.27 TgN yr-1と推定された。 地域別に見ると、南極海周辺での海洋起源放出量について既存インベントリが過大評価傾向にあることがわかった。一方熱帯域および中高緯度域の地表からの放出量についてはそれぞれ過少および過大評価傾向にあったと考えられ、別の観測の結果とも整合的であった。また全球の陸域および海洋起源放出量の時間変動についてはエルニーニョ・南方振動と強い相関が見られた。地域ごとの陸域起源放出量の2000年代と2010年代の間の変化量について調べたところ、北アメリカ、中央および熱帯アメリカおよび中央アフリカ、南、東および東南アジアで増加傾向が見られた。一方ヨーロッパでは減少する傾向が見られたが、これは化学工業に起因すると推定された。また15地域中3地域(東アジア、北アメリカおよび中央アフリカ)および南極海において、季節変化について今後の改良が必要なことが示唆された。陸域生態系モデル(VISIT)による推定放出量を用いた場合、観測から推定される1978年以降の増加速度をよく再現しているが、一方で窒素肥料の施肥から大気への放出にかかる変換時定数については改めて検討する必要があることが示唆された。

著者

Kayoko H. Murakami Atsuko K. Yamazaki Rui Takahashi Kenichi Kowata Jingge Ding Muhammad N. A. B. M. Anuardi Kenichiro Yoshikawa Katsutoshi Waki

出版者

International Society for Tourism Research

雑誌

Journal of Global Tourism Research (ISSN:21899274)

巻号頁・発行日

vol.6, no.1, pp.45-54, 2021 (Released:2021-05-15)

参考文献数

20

被引用文献数

1

---

As the outbreak of the novel coronavirus disease caused great damage on inbound tourism in Japan, developing an effective promotion way to revitalize the inbound tourism is an important issue. Since many inbound tourists to Japan have expected healing and relaxing for their travels, motivating prospective tourists who look for these comforts is a key to increase the number of inbound tourists for the future. In this study, the authors conducted an experiment to examine whether photos (still image) or videos (moving image) of scenery are more effective to stimulate tourist’s interests to visit Japan with an approach utilizing neuromarketing. In the experiment we recorded the brain activity of subjects, which is monitored as the amount of cerebral blood flow change by using near-infrared spectroscopy (NIRS) and obtained their impression evaluation for each scenery image by using Semantic Differential (SD) method. The result of the experiment showed that the amount of cerebral blood flow change for both still images and moving images was similar. Moreover, the result of SD measurement for both still and moving images was also similar. Additionally, it illustrated that the mean values of SD adjectives related to healing were higher than other adjectives. These results suggest that the effectiveness of using photos or videos of scenery for promoting tourism on SNS or website does not have a big difference. In addition, the photos or videos which often give relaxing feelings can be effective to motivate prospective tourists who seek a relaxing time in Japan.