著者
Shepard John W. Meyer Katherine A.
出版者
The Ichthyological Society of Japan
雑誌
魚類学雑誌 (ISSN:18847374)
巻号頁・発行日
vol.25, no.3, pp.159-164, 1978

伊豆諸島の三宅島から得られたべラ科の1新種ウスバノドグロベラ<I>Macropharyngodon moyeri</I>を記載した.本種は<I>M. kuiteri</I>以外の同属の既知種とは, 歯が扁平であることと, 背鰭と臀鰭の条数が12本といずれも1本多いことで識別できる.<I>M. kuiteri</I>万とは色彩および各側線鱗の各部開孔数で区別される.
著者
増田 剛 坪井 秀行 古山 通久 遠藤 明 久保 百司 Del Carpio Carlos A. 宮本 明
出版者
一般社団法人電子情報通信学会
雑誌
電子情報通信学会技術研究報告. SDM, シリコン材料・デバイス
巻号頁・発行日
vol.105, no.318, pp.31-32, 2005-09-30

低エネルギーイオン注入法による極浅p^+/n接合面の形成は、半導体デバイス製造プロセスに欠かせないものとなっている。本研究では、低エネルギーイオン注入法による極浅p^+/n接合形成プロセスにおける原子ダイナミクスを解明するために、当研究室独自に開発した数千原子からなる大規模系の計算を可能とするハイブリッド量子分子動力学計算プログラムを用いて、プリアモルファス化したシリコン基板へのドーパント注入シミュレーションを行った。
著者
John B. MORRIS Joseph A. CICHOCKI Gregory J. SMITH
出版者
日本毒性学会
雑誌
日本毒性学会学術年会 第43回日本毒性学会学術年会
巻号頁・発行日
pp.S2-1, 2016 (Released:2016-08-08)

That respiratory defense mechanisms are stimulated by oxidants/electrophiles has long been appreciated. Our work has focused on characterizing two such defense pathways from an inhalation toxicological perspective: 1) neuronal reflex responses, initiated by the transient receptor potential ankyrin 1 (TRPA1) receptor, and 2) cellular antioxidant defenses initiated via the nuclear factor erythroid 2-related factor (NRF2). TRPA1 and NRF2 are oxidant sensitive receptors expressed throughout the respiratory tract. They are activated by reactive inhaled agents (acrolein) or by local metabolic activation of inhaled or systemically delivered agents (naphthalene, acetaminophen). Exposure to inhaled and systemic oxidants in combination results in synergistic TRPA1 and NRF2 responses. Oxidant responses have also been characterized among respiratory tract regions and between electrophiles with differing reactivity. When normalized to delivered dose, inhaled oxidant/electrophile induction of pro-inflammatory genes is similar throughout the airways, however, differences exist in the NRF2-dependent antioxidant gene induction patterns between regions. Activation of both TRPA1 and NRF2 depends on toxicant interaction with sulfhydryl moieties. The oxidant exposure levels necessary for activation of TRPA1 and NRF2 responses are similar suggesting both oxidant sensors are of comparable sensitivity. While soft electrophiles, such as acrolein, react with sulfhydryls, hard electrophiles, such as diacetyl, do not. Unlike acrolein, inhaled diacetyl is only a weak activator of either neuronal reflexes or NRF2 pathways, suggesting the chemical electrophilic reactivity profiles of TRPA1 and NRF2 are comparable. Overall, the oxidant sensitive receptors TRPA1 and NRF2 demonstrate many toxicologically relevant similarities
著者
山崎 豊彦 ロセス S.A. 金子 正紀 ケービン N. 内藤 健一
出版者
The Japanese Association for Petroleum Technology
雑誌
石油技術協会誌 (ISSN:03709868)
巻号頁・発行日
vol.59, no.3, pp.216-226, 1994
被引用文献数
1

この研究は水蒸気攻法で, オイルサンドからビチューメンを回収した後, さらにビチューメンを回収する方法として, 水蒸気にヘキサンや石油ベンジンのような軽質炭化水素を利用する方法について研究したものである。ここに報告したのは温度250°Cおよび300°Cの水蒸気に上記の溶剤を加え, その回収実験を行ったもので, 16の実験結果について, 水蒸気のみで10時間回収を行った場合, 始めの5時間は水蒸気で回収を行い, その回収がほぼ完了したと見られる5時間後から, ヘキサン, 石油ベンジンを水蒸気のほぼ2%程度混入した場合の回収率について検討した。この結果, 石油ベンジンを混入した場合はヘキサン混入の場合より大量のビチューメンを生産し, 300°Cの場合, その回収率は最大で56.6%となった。
著者
David M. Boland Eric V. Neufeld Jack Ruddell Brett A. Dolezal Christopher B. Cooper
出版者
理学療法科学学会
雑誌
Journal of Physical Therapy Science (ISSN:09155287)
巻号頁・発行日
vol.28, no.12, pp.3398-3402, 2016 (Released:2016-12-27)
参考文献数
20
被引用文献数
35

[Purpose] To determine the intra- and inter-rater agreement of a mobile application, PostureScreen Mobile® (PSM), that assesses static standing posture. [Subjects and Methods] Three examiners with different levels of experience of assessing posture, one licensed physical therapist and two untrained undergraduate students, performed repeated postural assessments of 10 subjects, fully clothed or minimally clothed, using PSM on two nonconsecutive days. Anterior and right lateral images were captured and seventeen landmarks were identified on them. Intraclass correlation coefficients (ICCs) were calculated for each of 13 postural measures to evaluate inter-rater agreement on the first visit (fully or minimally clothed), as well as intra-rater agreement between the first and second visits (minimally clothed). [Results] Eleven postural measures were ultimately analyzed for inter- and intra-rater agreement. Inter-rater agreement was almost perfect (ICC≥0.81) for four measures and substantial (0.60<ICC≤0.80) for three measures during the fully clothed exam. During the minimally clothed exam, inter-rater agreement was almost perfect for four measures and substantial for four measures. Intra-rater agreement between two minimally clothed exams was almost perfect for two measures and substantial for five measures. [Conclusion] PSM is a widely available, inexpensive postural screening tool that requires little formal training. To maximize inter- and intra-rater agreement, postural screening using this mobile application should be conducted with subjects wearing minimal clothing. Assessing static standing posture via PSM gives repeatable measures for anatomical landmarks that were found to have substantial or almost perfect agreement. Our data also suggest that this technology may also be useful for diagnosing forward head posture.
著者
中川 聖一 Reyes Allan A. 鈴木 英之 谷口 泰広
出版者
一般社団法人情報処理学会
雑誌
情報処理学会論文誌 (ISSN:03875806)
巻号頁・発行日
vol.38, no.8, pp.1649-1658, 1997-08-15
参考文献数
16
被引用文献数
19

本論文では, 音声認識技術を利用した英会話CAIシステムについて述べる. これは, システムが, 学習者の発話を自動音声認識により理解し, 待ち時間なしで適切な応答を音声で出力し, 対話を進めることにより, スピーキングとヒアリングの能力を高めるものである. まず, 日本人の発声した英語の音声認識を行うためには日本人の英語発音モデルを用いる必要のあることを示す. 次に, 評価実験として4人の日本人男性にこの英会話CAIシステムを使用してもらった評価実験結果について述べる. 使用前と使用後のスピーキングとヒアリングの能力の差を比較したところ, 全員に能力向上がみられた. またアンケートの結果, 本システムを引き続き利用したいとか, システムの応答時間はちょうど良いといった意見が多く得られた.
著者
Masaki Mizuno Jere H. Mitchell Scott A. Smith
出版者
一般社団法人日本体力医学会
雑誌
The Journal of Physical Fitness and Sports Medicine (ISSN:21868131)
巻号頁・発行日
vol.5, no.5, pp.339-347, 2016-11-25 (Released:2016-11-10)
参考文献数
120
被引用文献数
4

The cardiovascular response to physical exercise is abnormally exaggerated in hypertension. Since such responses potentially increase the risk for adverse cardiovascular events, it is clinically important to elucidate the cause of this cardiovascular hyper-excitability in this disease. Even if blood pressure is normal at rest, individuals displaying a heightened blood pressure response to exercise are more likely to develop future hypertension. Therefore, early detection of this abnormal circulatory response to physical activity could lead to the early treatment as well as prevention of hypertension. Much evidence suggests that the abnormal exercise pressor reflex (EPR; a reflex originating in exercising skeletal muscle) significantly contributes to the generation of the enhanced circulatory responses in this disease. In addition, it has been demonstrated that the EPR dysfunction is mediated by both mechanically-sensitive fibers associated with the muscle mechanoreflex and chemically-sensitive fibers associated with the muscle metaboreflex. This review focuses on the underlying mechanisms for this overactive EPR function in hypertension. Specifically, updates on our current understanding of the EPR in this disease as well as experimental models used to examine this reflex are presented.
著者
ワシリェフスキー A. A. 井上 紘一 福田 知子
出版者
北海道大学総合博物館 = Hokkaido University Museum
雑誌
北海道大学総合博物館研究報告 (ISSN:1348169X)
巻号頁・発行日
vol.1, pp.1-18, 2003-03-31

The sites of Yuzhnaya 2, Kedrinka, Baklan and Pavlovka, very similar to each other, were discovered in 1985-1989 in southeast of Sakhalin. The Aniwa culture, dated back by 14C to 2, 710-2, 250 BP was distinguished. Supposedly, its calendar (calibrated) age should be about 500-300 BC. A complex of this culture is characterized by such features as: * a concentrated structure of the settlements at maritime sites; * subterranean type of pit dwellings of oval shape; * earth walls of houses coated with white c1ay; * fireplaces with circles of stones; * flat bottom vessels decorated by the typical Jomon pattern (oblique rope impressions), apertures on the rim, and horizontal string impressions (Aniwa type); * stone industry based on the utilization of obsidian as a main raw material for tool manufacturing; * stemmed knives and trapezoid scrapers, one angle pointed. By the complex of these features the Aniwa culture is very close to the Hokkaido cultures of Epi Jomon, and this makes us think it to be the most northern branch. The appearance of the Epi Jomon in Sakhalin is the archaeological reflection of the movement of the Paleo-Ainu tribes to the North Aniwa type pottery is different from that Epi Jomon pottery which was found in the southwest and in the middle south of Sakhalin island. The problems of the origin of Susuya pottery and of the connections between Susuya and the Epi Jomon people came into existence since the Susuya type pottery was distinguished by Professor lto Nobuo. In the 1930s and also in the 1980s and 90s some sites of Epi Jomon origin were discovered. The author proves Susuya to be a separate archaeological culture which played a role of the cultural fundament of the Okhotsk cultures, appearing in the 1st millennium AD. The Aniwa culture was distinguished as a variant of the Epi Jomon on the basis of new information in the 1980s and 90s. It is supposed that during that period different cultural groups of Epi Jomon societies were penetrating Sakhalin from the south and settled there. According to the calibrated radiocarbon dates, the peak of migration was about 5th to 2nd centuries BC. We noticed that the complexes of Susuya and Epi Jomon are situated in the same archaeological layers. It is supposed that within the ear1y Susuya time (5th to 2nd centuries BC) these two cultures coexisted in southern Sakhalin. North Sakhalin culture population (Nabil' type) was neighbor to the latter, seeing very similar to the culture of Susuya.
著者
A.Rustamani Maqsood Kanehisa Katsuo Tsumuki Hisaaki Shiraga Takashi
出版者
岡山大学資源生物科学研究所
雑誌
岡山大学資源生物科学研究所報告 (ISSN:0916930X)
巻号頁・発行日
vol.1, no.1, pp.9-20, 1992

Plant-feeding arthropods, in the course of evolution have adapted differentially to their plant host and thereby gained access to the available resource. Plants responded by developing chemicals and morphological defense to arthropods. Some secondary metabolic substances in plants have been assumed to be toxic or deter feeding. Aconitic acid in the barnyard-grass subspecies, Echinochloa oryzycola Vasing has been reported to be an active component against brown rice planthopper Nilapalvata lugens (Stal) (Kim et al. 1976). Aphids, Ropalosiphum padi. L., R. maidis (F.), Schizaphis graminum (Rondani)and Sitobion akeviae (Shinji), are important pests of barley (Hordeum vulgare L.) and wheat (Triticum aesstivum L.). On barley plants, more than seven aphids per stem causes yield loss (Hansen 1990). R. maidis sometimes severely infested corn plants (Zea mays L.), the leaves being wet by honeydew. Melanaphis sacchari (Zehntner) caused brownish decay of leaves of a susceptible line・ of sorghum Sorghum bicolor Moench. We examined the relation between aconitic acid contents and aphid densities in wheat, barley, corn, sorghum, barnyard grass and rice (Rustamani et al. 1992a). The plants containing larger amounts of aconitic acid showed a moderate degree of resistance to aphids. The findings obtained on additional lines in 1991, and on other components, such as DIMBOA (2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one), are reported herein.禾本科植物の葉に含まれているアコニット酸を抽出定量し、寄生性のアブラムシに対する耐性との関係を調べた。トウモコロシの16系統、典型的な抵抗性と感受性のソルガムの2系統、ヒエ類の3亜種、イネの2系統、オオムギの9系統とコムギの8系統について比較した。一般的に逆齢期の植物は老熟期の植物より高い含量であった。トウモコロシは全体として200μg/g以上を含有する系統が多く、アブラムシに対して耐性を示した。外部からトウモロコシアブラを導入し、そう推移とアコニット酸の関係を調べたところ、比較的耐性を示す系統は多量に含有し、アブラムが寄生し易い系統は少量であった。ヒエノアブラムシに耐性のソルガムの系統は感受性の系統の約2倍のアコニット酵を含量していた。タイヌビエのみがイヌビエ、ヒメタイヌビエ、イネのホウレイとアケボノと異なって、成熟するにつれてアコニット酸の含有量が増加していた。このことはトビイロウンカによって稲田が坪枯れの時にタイヌビエのみが青春としており、それはアコニット酸によるとの報告と一致している。オオムギは比較的少量のアコニット酸が検出され、耐性における作用は弱く、オオムギには特有のグラミンがあり、これがアブラムシに対する耐性の主要因に成っていると考えられた。コムギは少量のアコニットさん含有であり、グラミンは検出されなかった。数個の未同定の作用力不明の多量成分と摂取忌避作用の認められる微量のフェノール酸もあった。いくつかの成分が耐虫性成分であるが、アコニット酸も重要な要因と考えられた。
著者
Hebert S. C. Fabre Ricardo L. Navarro Paula V.P. Oltramari-Navarro Rodrigo F. Oliveira Deise A. A. Pires-Oliveira Rodrigo A. C. Andraus Nelson Fuirini Karen B. P. Fernandes
出版者
理学療法科学学会
雑誌
Journal of Physical Therapy Science (ISSN:09155287)
巻号頁・発行日
vol.27, no.6, pp.1645-1648, 2015 (Released:2015-06-30)
参考文献数
27
被引用文献数
2 44

[Purpose] This study aimed to evaluate the anti-inflammatory and analgesic effects of intraoral application of low-level laser therapy (660 nm) to control pain, swelling and interincisal opening following the extraction of mandibular third molars. [Subjects and Methods] Ten patients underwent removal of lower third molars using the same surgical protocol and pharmacological approach. In the postoperative period, all patients received four consecutive daily sessions of low-level laser therapy, beginning 24 hours after the surgery. Intraoral applications using the diode laser with 660 nm wavelength in the continuous scan mode were performed covering the entire surgical area, which was divided into four quadrants, each of 1 cm2 area at a distance of 1 cm. The energy applied at each point was 5 J/cm2 during 8 seconds. [Results] The swelling and interincisal opening returned to normal 24 hours after the first low-level laser therapy application (Friedman test). Moreover, the pain intensity was reduced on the third postoperative day, according to the Friedman test. [Conclusion] Low-level laser therapy (660 nm), at the dosimetry used in this study, was effective in reducing postoperative pain and swelling following oral surgery.
著者
Saejong YOO Jiyong KIM Hyun-Wook MYUNG Suhan WOO Dai-Jung CHUNG A-Jin LEE Han-Jun KIM Sun-Hee DO Hwi-Yool KIM
出版者
公益社団法人 日本獣医学会
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
pp.16-0186, (Released:2016-10-15)
被引用文献数
4

A 12-year-old, spayed female Schnauzer presented with constipation. A mass was observed in the pelvic cavity, and metastasis was not identified. Mass resection was performed through celiotomy with pubic osteotomy, and hemangiosarcoma was diagnosed. At 10 weeks post-operatively, the patient died of multiple metastasis. Primary intrapelvic hemangiosarcoma is rare in dogs.
著者
Juan J. Chillarón Mercè Fernández-Miró Mercè Albareda Sara Fontserè Cristina Colom Lluís Vila Juan Pedro-Botet Juana A. Flores Le-Roux
出版者
(社)日本内分泌学会
雑誌
Endocrine Journal (ISSN:09188959)
巻号頁・発行日
pp.EJ16-0195, (Released:2016-07-22)
被引用文献数
6

Testosterone deficiency (Td) has been associated with the metabolic syndrome. Few studies have evaluated this condition in type 1 diabetes (T1D). The primary aim of this study was to evaluate the effectiveness of testosterone undecanoate (TU) on insulin sensitivity, glycemic control, anthropometric parameters, blood pressure and lipid profile in patients with Td and T1D. We performed a randomized placebo-controlled multicenter study. Inclusion criteria: a) age ≥ 18 years; b) autoimmune diabetes; c) Td (total testosterone <10 nmol/L or calculated free testosterone <225 pmol/L and low/normal LH; d) ability to sign informed consent; e) comply with the study protocol. Exclusion criteria: a) pituitary tumor, empty sella, hyperprolactinemia, panhypopituitarism or secondary hypogonadism; b) contraindications for treatment with testosterone undecanoate (TU); c) patients who did not agree to sign their informed consent. Six patients were randomly assigned to testosterone undecanoate (TU) treatment and 7 to placebo with the following dosing schedule: baseline, 6 weeks and 16 weeks. Blood test, anthropometric parameters, blood pressure and insulin sensitivity were determined at baseline, 6, 16 and 22 weeks. No differences were observed regarding insulin sensitivity, HbA1c or basal glucose, anthropometric parameters or blood pressure. At 22 weeks, the decrease in total cholesterol was 37.4 ± 27.5 mg/dL in the TU group compared with an increase of 13.2 ± 17.8 mg/dL in the placebo group (P<0.005), and LDL cholesterol concentration decreased 30.2 ± 22.1 mg/dL, compared with an increase of 10.5 ± 13.4 mg/dL in the placebo group (P=0.004). We conclude that treatment with TU in patients with T1D and Td improves lipid profile, with no effects on metabolic control or anthropometric parameters.