著者

山本 晃之 根岸 健一 木下 果鈴 福井 絢子 上村 直樹 青山 隆夫

出版者

一般社団法人 日本医薬品情報学会

雑誌

医薬品情報学 (ISSN:13451464)

巻号頁・発行日

vol.21, no.1, pp.20-26, 2019-05-31 (Released:2019-06-21)

参考文献数

7

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Objective: It has been recognized that most medical institutions preferred the printed medium for their information sheets for patient education of inhaler usage. However, some questions have arisen. In a case where patients are not sufficiently informed of drug administration guidance due to limited information with only pictures and text, they might not be able to obtain a proper understanding. Contrarily, it is assumed that video medium, with audio and visual elements, is a format for education conveying a larger amount of information. We conducted comparative research regarding patient’s degree of understanding of inhalation guidance, comparing two groups of print- and video-medium-based instructions for inhaler usage and examined how effective two types of media explanations were on patients.Methods: Research participants were thirty persons visiting Jinjo Pharmacy, who were randomly assigned to the print medium group and the video medium group. After one group read and saw an explanation sheet of an inhaler where the maker wrote inhalation instructions and the other group watched an instruction video, the two groups practiced inhaler usage. Evaluation was performed with specified items and comprehensive assessment, and in addition, the time required for inhalation was measured.Results: Score of the evaluation score was statistically significantly higher in the video medium group than in the print medium group in score of specified items and score of comprehensive assessment, and was also significantly shorter in the operation time of the inhaler.Conclusion: This study clarified that the video medium group had fewer improper inhalation occurrences and shorter operation time and, therefore, showed the effectiveness of the video medium. It is recommended that the video medium should be actively utilized,which could improve patient medication adherence. Accessibility is required for patient education to achieve inhaler techniques by watching video-based instruction.

著者

壁矢 健司 佐藤 宏樹 堀 里子 三木 晶子 三浦 康正 澤田 康文

出版者

一般社団法人 日本医薬品情報学会

雑誌

医薬品情報学 (ISSN:13451464)

巻号頁・発行日

vol.21, no.2, pp.49-56, 2019-08-31 (Released:2019-10-10)

参考文献数

12

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Objective:Marketing specialists (MSs) from pharmaceutical wholesalers might shore up post-marketing surveillance (PMS) by pharmaceutical manufacturers. The purposes of this study were as follows: to research problems in PMS found by market specialists, to find solutions for these problems, and motivating MSs to work on PMS. Methods: We conducted a workshop with 12 MSs, who were already working on PMS operations. Participants were divided into three groups. Each group discussed problems with their PMS operations using the KJ method, discussed the potential solutions for the problems, and finally presented them in a plenary debate session. Questionnaire surveys were conducted for the participants before, immediately after, and 6 months after the workshop. Results: This workshop revealed two crucial and urgent problems on PMS faced by MSs: lack of feedbacks to clinical site and lack of publicity of the significance of PMS by MSs. Several solutions were suggested: browsing system of collected information, publication of the stages of improvement in pharmaceutical preparations and packaging, and distributing leaflets about PMS by MSs. In addition, this workshop conferred a positive influence on the participants: in the post-workshop questionnaires, most of the participants answered that they could well understand the problems (92%) and the solutions (75%) on PMS, and that they could improve their attitudes toward PMS operations (83%). . Conclusion: This workshop was quite effective for most of the participants in searching the problems, considering the solutions, and improving their attitudes. Organization of several such workshops might result in better PMS by MSs.

著者

松木 祥彦 塚本 哲也 細山田 真 渡部 多真紀 渡辺 茂和 土屋 雅勇

出版者

Japanese Society of Drug Informatics

雑誌

医薬品情報学 (ISSN:13451464)

巻号頁・発行日

vol.15, no.2, pp.51-56, 2013 (Released:2013-09-05)

参考文献数

17

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Objective: In previously reported comparisons of aminoglycoside antimicrobials administered once daily versus multiple administration, toxicity was found to be equal or lower while efficiency remained high.  However, there are few reports on the clinical condition of targeted elderly persons.  The objective of this study was to evaluate the once-daily dosing regimen of 400 mg of AMK involving elderly pneumonia patients aged 75 years or older with regard to clinical evaluation including the efficacy and toxicity.Methods: A survey to clinically evaluate the efficacy and toxicity of 400 mg AMK administered once daily for 30 min at 24 h intervals was carried out.  One hundred twenty-seven patients with pneumonia and who were 75 years or older at Funabashi General Hospital were targeted, with the aim of an expected clinical effect of Cmax/MIC≥ 8-10.  Serum concentration monitoring was carried out after administration began.Results: There were 121 patients (95.3%) of controlled AMK concentration with a trough serum concentration of <10 μg/mL, which is a safe concentration range.  There were 6 patients (4.7%) where trough serum concentration in the toxic range >10 μg/mL, with an average at 15.1±5.0 μg/mL, and the average administration days were 7.5 ± 3.3 days.  Moreover, before/after AMK administration, there were 3 patients (2.4%) where CRE values increased more than a 150% over the previous values, and were evaluated as renal dysfunction.  Average trough serum concentration at that time was 3.6 ± 1.1 μg/mL, and average number of days of administration were 13 ± 1.4 days.  Patients of trough serum concentration in the toxic range >10 μg/mL were not included.  The average peak serum concentration calculated by Winter’s pharmacokinetic parameter and the 1-compartment model was 35.3 ± 8.0 μg/mL, and the average Cmax/MIC which correlates with the AMK effect was 9.9 ± 2.2.  The treatment was effective for 83 (65.4%) of the 127 patients.Conclusion: By once-daily administration of AMK 400 mg to aged persons 75 years or older, change in trough serum concentration into a safe range and Cmax/MIC≥ 8-10, the level at which clinical effectivity can be expected, could be achieved.  This administration method is shown to be useful in maintaining AMK in the target serum concentration range for aged persons.

著者

三井 梨恵子 秋好 健志 今岡 鮎子 望月 眞弓 大谷 壽一

出版者

Japanese Society of Drug Informatics

雑誌

医薬品情報学 (ISSN:13451464)

巻号頁・発行日

vol.17, no.2, pp.77-86, 2015 (Released:2015-10-01)

参考文献数

31

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Objective: Clinical trials are designed to clarify the dose-dependency of drugs.  However, the dose-dependency of adverse drug reactions (ADR), especially in the subtherapeutic range, often remains unclear.  Whether decreasing a drug’s dose would reduce the risk of ADR is of interest to both clinicians and regulators.  This study aimed to clarify the dose-dependency of ADR during subtherapeutic exposure to non-steroidal anti-inflammatory drugs, immunosuppressants, β-adrenoceptor antagonists, or corticosteroids.Methods: Data about the ADR risk profiles and the area under the concentration curve (AUC) values of the examined drugs during their subtherapeutic administration, e.g., after their topical or low-dose oral administration, were collected from the literature and compared with data obtained during the therapeutic administration of the drugs; i.e., at the standard oral dosage.Results: The drugs that exhibited AUC of ≥20% during their therapeutic administration continued to cause significant systemic ADR during their subtherapeutic administration.  Whilst the drugs that demonstrated AUC of 3-20% during their therapeutic administration continued to cause systemic ADR during their subtherapeutic administration, the ADR tended to be less frequent.Conclusion: The dose-dependency of ADR can be estimated by comparing the AUC and ADR risk profile data for a drug obtained during its topical, parenteral, or low-dose oral administration with that obtained during its oral administration at the standard dose.  However, some studies have detected high ADR frequencies even during reduced systemic exposure, suggesting that factors affecting the risk of ADR, e.g., patients’ background data, should be carefully matched between the datasets being compared.

著者

田中 秀和 三上 明子 藤澤 哲也 若林 進

出版者

Japanese Society of Drug Informatics

雑誌

医薬品情報学 (ISSN:13451464)

巻号頁・発行日

vol.19, no.3, pp.111-120, 2017 (Released:2017-12-27)

参考文献数

10

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Objective: There are prescription medicines with design-like (misunderstanding) bisection lines although these are not admitted as bisection lines according to dosage instructions.  We often find differences in identifying bisection lines among medical facilities in case of same tablets.  We conducted a survey about identifying bisection line-like design on tablets by pharmacists and investigated the reason for the discrepancy in identification among information service facilities.Methods: We conducted an online survey for pharmacists at hospitals, clinics, and pharmacies.  We selected the discrepancies in identification among the facilities involved in drug information services.Results: In this survey, 65.2% of pharmacists were aware of design-like bisection lines that are not permitted as bisection lines.  Further, 30.3% could not confirm if these were real bisection lines or design-like bisection lines by judging only from their surfaces.  The examination of two online media and a book offering drug information service showed different definitions depending on medicines.  These entities say they have obtained information by their own ways of source from pharmaceutical manufactures and sellers.Conclusion: Even for pharmacists, it is difficult to distinguish actual bisection lines from design-like bisection lines.  The differences in identification among facilities dealing with medical information services are undesirable issues.  Regulations by GMP or other legal methods are required for appropriate information control by pharmaceutical manufacturers and sellers.

著者

小野 寛之 佐藤 雄己 大山 展弘 中原 良介 倉成 正恵 伊東 弘樹

出版者

Japanese Society of Drug Informatics

雑誌

医薬品情報学 (ISSN:13451464)

巻号頁・発行日

vol.18, no.1, pp.7-12, 2016 (Released:2016-06-13)

参考文献数

8

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Background: Because generic medicines reduce the financial burden on patients and medical insurance providers, they become more popular year after year.  However, there are still few reports that analyze the efficacy and safety of generic medicines, especially in terms of their characteristics and side effects.Methods: Paclitaxel is an antineoplastic frequently used with good results in the treatment of breast cancer, ovarian cancer, gastric cancer, and angiosarcoma, but fat solubility is high and various kinds of adverse events, such as myelosuppression and arthralgia, peripheral neuropathy, and alcohol hypersensitivity are known to develop.  We investigated the efficacy, characteristics, and the incidence of adverse events for the generic product of paclitaxel.Results: Differences were found for the generic version in terms of the characteristics and preparation time.Conclusion: The incidence of adverse events was not significant, suggesting that the generic version could be a reasonable substitute.

著者

望月 眞弓 俵木 登美子 下堂薗 権洋 木村 通男

出版者

Japanese Society of Drug Informatics

雑誌

医薬品情報学 (ISSN:13451464)

巻号頁・発行日

vol.19, no.4, pp.N5-N9, 2018 (Released:2018-03-21)

参考文献数

4

著者

向井 淳治 石坂 敏彦

出版者

Japanese Society of Drug Informatics

雑誌

医薬品情報学 (ISSN:13451464)

巻号頁・発行日

vol.15, no.1, pp.37-40, 2013 (Released:2013-06-06)

参考文献数

7

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Objective: The number needed to treat (NNT) is an index for determining the number of patients who need to be treated in order to prevent the occurrence of an adverse event when a new treatment instead of the standard one is used.Methods: The properties of NNT were examined by using the geometric distribution formula as the probability for preventing the occurrence of an adverse event in the NNT.Results: When the NNT was enlarged infinitely, the probability for the prevention of an adverse event by NNT was found to be 63.2% (=1−e−1), and the number of patients who needed to show adverse event prevention at the probability of 95% was about 3 times as that of the NNT (Rule of Three).Conclusion: When the effect of new treatment needs to be evaluated based on NNT, one should take these properties of NNT into consideration.

著者

出川 えりか 安藤 崇仁 安藤 正純 加藤 剛 嶋村 寿 永田 あかね 村野 哲雄 林 広紹 馬場 寛子 齋藤 百枝美

出版者

一般社団法人 日本医薬品情報学会

雑誌

医薬品情報学 (ISSN:13451464)

巻号頁・発行日

vol.20, no.3, pp.189-199, 2018-11-30 (Released:2018-12-08)

参考文献数

10

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Objective: Caffeine may cause dependence and sleep disturbance, and interact with psychotropic drugs. Therefore, the caffeine intake of patients with mental disorders should be monitored. However, in Japan, there is no report on the effects of caffeine in mental disease patients or on their caffeine intake. Therefore, we conducted a questionnaire survey to clarify the perception of caffeine for psychiatric outpatients.Methods: We conducted an anonymous survey on caffeine recognition for outpatients at 8 medical institutions that advocate psychiatry.Results: We collected questionnaires from 180 people. The knowledge of foods containing caffeine tended to be high in those who had a positive attitude toward caffeine. More than 90% of those surveyed knew that coffee contains caffeine, but cocoa and jasmine tea were recognized by less than 25%. Of those surveyed, 39.4% consumed caffeine‐containing beverages at night. In addition, the rate of consumption of caffeine‐containing beverages tended to be higher at night because they had a positive attitude toward caffeine.Conclusion: The knowledge and intake situation of caffeine by patients with mental disorders differed depending on their interests and way of thinking about caffeine. As caffeine intake may influence psychiatric treatment, correct knowledge regarding caffeine is important.

著者

山本 美智子

出版者

Japanese Society of Drug Informatics

雑誌

医薬品情報学 (ISSN:13451464)

巻号頁・発行日

vol.20, no.1, pp.N1-N4, 2018-05-31 (Released:2018-06-16)

参考文献数

6

著者

岡本 有紀子 服部 慈久 中村 康夫 紙本 薫 鈴村 宏

出版者

一般社団法人 日本医薬品情報学会

雑誌

医薬品情報学 (ISSN:13451464)

巻号頁・発行日

vol.17, no.2, pp.59-68, 2015

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<b>Objective: </b>Incidents, such as disturbance of consciousness due to adverse reactions of medications during automobile driving, could cause a serious accident.  Although automobile driving is indicated to be "prohibited" in the package inserts of many drugs, no explicit guidelines are available in Japan on specific guidance to patients.  Therefore, we attempted to prepare guidelines for medication guidance regarding automobile driving.<br><b>Methods: </b>We investigated the number of incidents involving traffic accidents and the disturbance of consciousness cases reported in "Japanese Adverse Drug Event Report" database by "Pharmaceuticals and Medical Devices Agency (PMDA)."  We also analyzed descriptions regarding automobile driving found in package inserts and guidelines to determine a risk level for each medication.<br><b>Results: </b>Guidelines for medication guidance were prepared based on four-level classification of drugs for which "prohibition" of automobile driving was indicated in their package inserts; these levels are "conform to pertinent guidelines," "strictly prohibited," "prohibited," and "conditionally prohibited."  The contents of the guidance prepared for some drugs were different from their package inserts.<br><b>Conclusions: </b>The guidelines prepared in this study can be expected to become a support tool to ensure close attention to cautions regarding automobile driving.  Because some contents of the guidance are different from that described in the package inserts, it is desirable to obtain agreement with physicians in hospitals adopting these guidelines.  In addition, guidelines based on a broader range of information should be prepared in the future.

著者

千葉 健史 前田 智司 平舩 寛彦 工藤 賢三

出版者

Japanese Society of Drug Informatics

雑誌

医薬品情報学 (ISSN:13451464)

巻号頁・発行日

vol.19, no.4, pp.195-204, 2018 (Released:2018-03-21)

参考文献数

20

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Limited available information suggests that some drugs prescribed to pregnant and nursing women may influence the development of the mammary gland and the function of milk production during pregnancy and lactation, resulting in disturbance of breastfeeding.  The objective of the present study was to investigate the safety of these drugs, as well as to assess the presence of safety information regarding their effect on the fetus, the infant, mammary gland development and milk production, within the Ethical Drug Package Inserts (EDPI), the Drugs in Pregnancy and Lactation (DPL), and the Drugs and Lactation Database (LactMed).  Thirty-one drugs were prescribed to 24 pregnant women in Iwate Medical University Hospital.  None of these drugs provided information on the safety of the fetus in the EDPI, while 22 drugs provided this information in the DPL.  No information was provided in any of the 31 drugs regarding their influence on mammary gland development in the EDPI and DPL.  Sixteen drugs were prescribed to 40 nursing women in Iwate Medical University Hospital.  None of these drugs provided information regarding the safety of the infant in the EDPI, while this information was provided in the DPL of 10 drugs and in LactMed of 4 drugs, respectively.  No information regarding the effects on milk production was provided in the EDPI of any of the 16 drugs, while this information was present in the DPL for one drug and in LactMed for 4 drugs.  In conclusion, safety information of drugs about their potential adverse effects on the fetus and the infant, as well as on mammary gland development and milk production, should be included in multiple sources, including EDPI, DPL, and LactMed.  Notably, very few sources provide information on the influence of drugs on mammary gland development and milk production and this information should be enriched in future.

著者

齋藤 百枝美 安藤 崇仁 伊神 敬人 小中原 隆史 小松 洋平 高木 友徳 永井 典子 橋本 俊英 丹羽 真一

出版者

Japanese Society of Drug Informatics

雑誌

医薬品情報学 (ISSN:13451464)

巻号頁・発行日

vol.19, no.4, pp.172-179, 2018 (Released:2018-03-21)

参考文献数

10

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Objective: The maintenance and improvement of medication adherence are important in psychiatry.  In the case of patients using home healthcare services, it is necessary to improve their medication adherence through multi-professional collaboration.  However, appropriate methods or measures to provide them with information regarding psychotropics and resolve their problems during home visits have yet to be clarified.  We aimed to promote the appropriate provision of such information in home healthcare services for patients with mental disorders by clarifying the current status and details of information needed during home visits.Methods: A questionnaire survey was conducted in April 2016, involving healthcare professionals who worked in 9 facilities providing home-visit services for patients with mental disorders.Results: A total of 116 (86 females and 30 males) responded, among whom nurses accounted for the majority, at 81.9%, followed by psychiatric social workers, at 10.3%, and occupational therapists, at 7.8%.  More than 97% of all respondents assessed medication adherence.  Medication guidance tended to be provided within 15 minutes (81.9%) during each home visit, and the most frequent duration of such guidance was 6 to 10 minutes (37.9%).  Patients most frequently asked about adverse drug effects (57.8%), and the health professionals most frequently faced difficulty answering such questions among all the questions asked (46.6%).  Materials needed during home visits included: <brochures explaining the therapeutic and adverse effects of drugs>, <photographs of drugs>, and <a list of generic drugs>.  Some respondents also noted the necessity of materials that are easy to carry.Conclusion: The results clarified the details of information to be provided on administering home healthcare services for patients with mental disorders.  As various professionals are engaged in such services, and they are expected to have a certain level of ability to provide information, systems to effectively support information provision by them may be needed.

著者

橋本 貴尚 菊池 大輔 新沼 佑美 小原 拓 村井 ユリ子 畑中 貞雄 栃窪 克行 渡辺 善照

出版者

Japanese Society of Drug Informatics

雑誌

医薬品情報学 (ISSN:13451464)

巻号頁・発行日

vol.19, no.4, pp.158-171, 2018 (Released:2018-03-21)

参考文献数

15

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Objective: To evaluate (1) a questionnaire for pharmacists on learning about drug information (DI) and using DI in practice, and (2) our DI seminar.Methods: (1) 72 hospitals and 105 community pharmacists in Miyagi, Japan were recruited.  The questionnaire included items on DI activities and questions about topics that pharmacists “want to study.”  (2) We held a seminar based on the questionnaire results and the reports of six pharmacists (one from a nonprofit corporation specializing in disseminating information on dietary supplements, one acute care pharmacist, two chronic and cancer hospital pharmacists, one community pharmacist, and one belonging to a community pharmacist association).  At the end of the seminar, participants were asked to complete an evaluation questionnaire on the seminar.Results: (1) The DI activity “participate in scientific meetings and collect information” was associated with other DI activities among both hospital and community pharmacists.  Multivariate analyses revealed that this DI activity was more strongly significantly associated with the topics “want to study techniques for presentation skills” (p<0.0001) and “want to study other DI practices” (p=0.008) than other DI activities.  (2) Sixty seven participants attended the seminar.  According to the evaluation questionnaire, the mean grade for the seminar was 80.5/100 points, and 96% of participants agreed with the “necessity of information sharing.”Conclusion: Participation in scientific meetings is important for pharmacists to develop their DI practice, and encourages information sharing between hospital and community pharmacists.  Environments in which more pharmacists have opportunities to participate in scientific meetings and related seminars are needed.

著者

佐藤 弘康 平沢 晋太郎 門野 冴美 晴山 知拓 藤田 剛平 金高 勇介 田村 広志 小森 均

出版者

一般社団法人日本医薬品情報学会

雑誌

医薬品情報学 (ISSN:13451464)

巻号頁・発行日

vol.19, no.1, pp.32-36, 2017-05-31 (Released:2017-06-16)

参考文献数

10

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Objective: Currently, the creation of a pharmaceutical risk management plan (RMP) for new drug information is obliged to pharmaceutical companies.  The created RMP is published on the Pharmaceuticals and Medical Devices Agency (PMDA) website.  RMP is a useful information source to ensure drug safety by healthcare professionals, including pharmacists.  “Risk minimization activities” of the RMP are especially important elements for healthcare professionals because they describe measures to minimize risk to patients.  We conducted a cross-sectional survey of the description of the contents of “risk minimization activities” in the RMP.Methods: The RMP of 177 drugs that had been published in February 22, 2016 were investigated.Results: Total risks enumerated for the study drugs were 1,678.  “Routine risk minimization activities” constituted 92.0% of total risks.  The most listed item on “routine risk minimization activities” was “attention on the product labeling of the drug package insert” (91.3%).  Differences in the expression level on “attention on the product labeling” were observed.  On the other hand, the most listed item of “additional risk minimization activities” was “the creation of documents for healthcare professionals” (38.3%) and “implementation of Early Post-marketing Phase Vigilance” (27.1%).Conclusion: A clear understanding of RMP by healthcare professionals is important.  In the RMP, “risk minimization activities” (especially “additional risk minimization activities”) are the most important contents for healthcare professionals, because they include information of documents created by the pharmaceutical company for patient safety.  The level of description of the contents of RMP varies between drugs.  It is essential that these descriptions be uniform the expression level to be easily and accurately utilized by healthcare professionals.

著者

平山 匡彦 鈴木 慎太郎 井上 広平 作元 誠司 井手 陽一 北原 敏弘 中野 正治 宮崎 長一郎 嵩下 賢 出口 法隆 佐藤 宏樹 三木 晶子 澤田 康文

出版者

一般社団法人日本医薬品情報学会

雑誌

医薬品情報学 (ISSN:13451464)

巻号頁・発行日

vol.18, no.2, pp.87-94, 2016 (Released:2016-09-27)

参考文献数

3

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Objectives: First steps to promote the proper use of medicines in remote islands and rural areas are as follows: (1) recognition of the profession of “pharmacist” from secondary-remote-island residents who do not have a pharmacy or drugstore or the opportunity for pharmacist contact and (2) an understanding by remote-island residents of the advantages of having a “family pharmacist.”Methods: Repeated “medicine information and consultation sessions” for secondary-remote-island residents of Japan’s Nagasaki Prefecture were held.  Residents were then surveyed for changes in awareness of or demand for pharmacists and the nature of such changes.Results: Before the information sessions, 29.7% of residents did not recognize the profession of pharmacy, but the extent of their recognition increased after information sessions were concluded.  They were asked “Who explains medicines in a way that is easy to understand ?”; more than half responded “doctors” before the information session, but after information sessions were concluded, those who said “pharmacists” increased.Conclusion: Conducting “medicine information and consultation sessions” for residents of secondary-remote islands and rural areas enabled them to understand the profession of pharmacy.  The initiatives in the present study are first steps toward promoting proper use of medicines by residents of remote islands and rural areas who use “family pharmacies/pharmacists.”

著者

中 雄介 恩田 光子 山根 有香子 川口 祐司 中野 翔太 荒川 行生

出版者

一般社団法人日本医薬品情報学会

雑誌

医薬品情報学 (ISSN:13451464)

巻号頁・発行日

vol.18, no.2, pp.81-86, 2016 (Released:2016-09-27)

参考文献数

14

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Objective: The subjects of this study were consumers with cold-like symptoms who visited drugstores to purchase OTC drugs.  The purpose was to elucidate the factors that influence the intention of these consumers to consult pharmacists or sellers.Design: Analytic observational studyMethod: We conducted a survey of consumers who visited pharmacies or drugstores for cold-like symptoms.  Pharmacists and registered sellers (hereafter “pharmacists or sellers”) utilized tools to serve them, entering details in customer records.  We handed postcards to these consumers asking them to respond to questions about the prognosis and the degree of satisfaction about the service they had received.  We then used the customer records and follow-up results to perform linear regression analysis with “I would like to consult the pharmacist or seller again” (hereafter “desire for consultation”) as the dependent variable, and the usefulness of the advice and degree of satisfaction about the explanation and service as the independent variables.Results: We analyzed the data of 81 consumers for whom we were able to match the customer records and postcards.  The linear regression analysis indicated that “the usefulness of the advice (coefficient of standardization: 0.73)” affected the desire for consultation most, followed by “the degree of satisfaction about the service (coefficient of standardization: 0.24).Conclusion: We verified that, in self-medication assistance, advice that lets consumers feel the consultation was actually “helpful” by focusing on individual needs, and good customer service were necessary to increase the desire for consultation with pharmacists or sellers, and to encourage actual consultation.

著者

清水 るみ子 藤田 圭子 村井 美香 井口 伸 山岡 由美子

出版者

一般社団法人日本医薬品情報学会

雑誌

医薬品情報学 (ISSN:13451464)

巻号頁・発行日

vol.13, no.4, pp.173-182, 2012 (Released:2012-03-15)

参考文献数

19

被引用文献数

1

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Objective: The aim of this study was to ascertain information on supplements and health foods desired by consumers, as well as consumer demands in pharmacies and drugstores.Method: We conducted a questionnaire survey of 740 patrons of two drugstores.  And data from this questionnaire survey was analyzed by simple and cross tables.Results: We received responses from 206 patrons (response rate: 27.8%).  The level of recognition that some supplements should not be taken by consumers with past illnesses was low among those who are older than 50 years.  Furthermore, the percentage of the population that does not recognize the possibility of interactions between supplements was higher.  In addition, it was suggested that, regardless of the low recognition level, consumers did not try to improve their knowledge by obtaining more information.  People who take supplements to improve dietary imbalances were found to have a strong desire for a short course in pharmacies and drugstores, and they also desire supplement advisers to be available at each drugstore in comparison with people who don’t select the choice “to improve dietary imbalances”.Conclusion: Thus, the present findings suggest that the level of consumers’ knowledge and their desired information differ depending on age.  Furthermore, consumers’ demands in pharmacies and drugstores differ depending on consumers’ intent to take supplements.  Therefore, it is important for pharmacists to provide information that is useful for individual consumers in consideration of consumers’ age and intent, and pharmacists must be able to independently identify consumers’ needs.

著者

佐島 進 櫻井 秀彦 我妻 拓哉 佐藤 陽介 早瀬 幸俊

出版者

一般社団法人日本医薬品情報学会

雑誌

医薬品情報学 (ISSN:13451464)

巻号頁・発行日

vol.17, no.3, pp.118-124, 2015-11-30 (Released:2015-12-18)

参考文献数

19

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Objective: Many studies on patient satisfaction are conducted in community pharmacies.  In contrast, the present study assess the community pharmacy function and to the best of our knowledge, appears to be the first to evaluate the professional functions of pharmacists.Methods: In September 2010, in 1 week, we conducted a survey that focused on pharmacists’ professional abilities.  I subjected the responses to factor analysis and covariance structure analysis.Results: We obtained 2,506 effective responses (appropriately completed and returned questionnaires) of the 4,633 questionnaires originally distributed.  Data of seven dimensions were obtained for factor analysis.  In all, the various information provision services rendered by a pharmacist were not significant.  According to the covariance structure analysis, “safety” (a pharmaceutical management item) and “responsiveness” (a complimentary element) were significant factors.  Differences in the degree of influence were confirmed for each parameter in the analysis, depending on the parameter.  In addition, the information provision services were significant during the acute period.Conclusion: Because the information provision services were not significant, the influence of “asymmetric information” warrant further analysis according to the specialty.  I believe that it is necessary to examine asymmetric information in greater detail in the future.  In addition, I think that an interventional study that is based on these results is also necessary.

著者

中山 雅裕 濱田 昌志 深津 佳代 門林 宗男 大野 雅子 桂木 聡子 天野 学 森山 雅弘

出版者

一般社団法人日本医薬品情報学会

雑誌

医薬品情報学 (ISSN:13451464)

巻号頁・発行日

vol.17, no.1, pp.11-14, 2015 (Released:2015-06-28)

参考文献数

10

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Objective: In Japan, to prevent an increase in medical expenditure associated with development of super-aging society, the use of generic drugs is being promoted.  To help patients financially and meet their various other needs, generic drugs (e.g., orally disintegrating film formulations) whose dosage forms do not exist for original drugs are manufactured and distributed.  In this study, to evaluate the characteristics of an orally disintegrating film formulation, we performed dissolution, disintegration, and simulated intraoral tests of Amlodin® tablets 2.5 mg, Amlodin® OD tablets 2.5 mg, and Amlodipine OD film 2.5 mg that were manufactured by TEVA-KOWA PHARMA Co., Ltd.Methods: Dissolution and disintegration tests were performed in line with the Japanese Pharmacopoeia, Sixteenth Edition, and the dose of amlodipine was determined by high-performance liquid chromatography.  During the simulated intraoral test, the tested drugs’ disintegration in purified water and artificial saliva was observed macroscopically, and recorded using a digital camera.Results: Since the each formulation showed an over 85.0% rate of dissolution 15 min after the initiation of the dissolution test, no difference was found in elution behavior.  Also, in the simulated intraoral test, the film formulation began to disintegrate the earliest (2 and 10 min when using purified water and artificial saliva, respectively) among the tested drugs.Conclusion: Our findings suggest that orally disintegrating film formulations show superior disintegration to uncoated or orally disintegrating tablets, and benefits on taking medicine was observed.