著者

Nguyen-Van Triet Hori Noriyuki

出版者

Institution of Engineering and Technology

雑誌

IET Control Theory & Applications (ISSN:17518644)

巻号頁・発行日

vol.7, no.1, pp.80-89, 2013-01

被引用文献数

14 4

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A new approach is proposed for obtaining discrete-time models of a non-linear autonomous continuous-time system based on classification of, what is called in this study, a discrete-time integration gain. The models are expressed as a product of this gain and the system function that has the same structure as that of the continuous-time system. Sufficient conditions on this gain to make the model exact, in the sense defined in this study, are presented. A new discrete-time model is proposed for non-linear systems, which is approximate in general, but exact for linear systems. The method is applicable to any system that has a Jacobian matrix. As examples, van der Pol and Lorenz oscillators are examined and simulated to show that the proposed discrete-time models perform better than other discrete-time models that are known to the authors to be on-line computable, and tends to retain such key features as limit cycles and chaos, even for relatively large sampling periods.

著者

Kim Hyojung Sakamoto Kazuichi

出版者

Portland Press Limited

雑誌

Cell biology international (ISSN:10656995)

巻号頁・発行日

vol.36, no.2, pp.147-153, 2012-02

被引用文献数

59 16

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EGCG [(−)-epigallocatechin gallate], tea catechin, is one of the compounds that has been reported to act against obesity and diabetes. To determine the effect of EGCG on adipocyte differentiation, we treated 3T3-L1 preadipocytes with different catechins. Oil Red O staining showed significantly reduced intracellular lipid accumulation, especially with EGCG. Cell cycle analysis showed that EGCG inhibited cell proliferation by disturbing the cell cycle during the clonal expansion of 3T3-L1. RT-PCR (real-time PCR) demonstrated that EGCG noticeably reduced mRNA expression of PPARγ (peroxisome proliferator-activated receptor γ), C/EBPα (CCAAT/enhancer-binding protein α) and FoxO1 (forkhead box class O1). EGCG also caused a significant decrease in the transcription of FoxO1 – the forkhead transcription factor class O1 involved in adipocyte differentiation – via the PI3K (phosphoinositide 3-kinase)/Akt and MEK [MAPK (mitogen-activated protein kinase)/ERK (extracellular-signal-regulated kinase) kinase] pathways. These results suggest that EGCG suppresses the clonal expansion of adipocytes by inactivating FoxO1 via insulin signalling and stress-dependent MAPK pathways.

著者

中村 満紀男 岡 典子

出版者

福山市立大学教育学部

雑誌

福山市立大学教育学部研究紀要 (ISSN:21876347)

巻号頁・発行日

vol.1, pp.69-78, 2013-03

著者

国立歴史民俗博物館編 橋本裕之[ほか]執筆

出版者

平凡社

巻号頁・発行日

1992

著者

古屋 佳子

出版者

京都市立看護短期大学

雑誌

京都市立看護短期大学紀要 (ISSN:02861097)

巻号頁・発行日

vol.31, pp.113-123, 2006

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熟練技能を具えた身体と身体に根ざした知性は,徹頭徹尾社会的かつ歴史的な性格を刻印されている.反応し行動する能力としての身体は,意味を帯びた状況と,己の取り込んでいる文化的意味に反応するからである.(中略)つまり身体は無反応な機械と決して同列には考えられないこと,むしろ身体は社会的に定義された状況に対し,意味を通じて反応することで,回復を促進したり,逆に害を引き起こしたりするのだということをここで改めて確認しておきたいのである.

著者

三木 理斗

出版者

東京大学大学院工学系研究科 電気系工学専攻

巻号頁・発行日

2010-03-24

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報告番号: ; 学位授与年月日: 2010-03-24 ; 学位の種別: 修士 ; 学位の種類: 修士(工学) ; 学位記番号: ; 研究科・専攻: 工学系研究科電気系工学専攻

著者

Foote Daniel H.

出版者

有斐閣

雑誌

ジュリスト (ISSN:04480791)

巻号頁・発行日

no.1148, pp.165-173, 1999-01-01

著者

田中 智彦

出版者

慶応義塾経済学会

雑誌

三田学会雑誌 (ISSN:00266760)

巻号頁・発行日

vol.102, no.1, pp.63-89, 2009-04

出版者

ダイヤモンド社

雑誌

週刊ダイヤモンド

巻号頁・発行日

vol.100, no.47, pp.153-155, 2012-11-24

著者

志村 喬 稲葉 豊年

出版者

Japanese Society of Breeding

雑誌

育種学雑誌 (ISSN:05363683)

巻号頁・発行日

vol.2, no.4, pp.205-213, 1953-06-30 (Released:2008-05-16)

参考文献数

19

被引用文献数

1

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1. Several morphologicai and physiological characters of triploid varieties were compared with diploids. 2. There was no clear difference on the leaf size and shape between triploids and diploids, but triploid leaves were thicker than those of diploids. As a rule every internal tissue of triploid leaves was thicker than diploids. It is evident that triploid leaves had larger stomatas of which the distribution density vias lower, compared with diploids. 3. No difference between both the plants could be recognized on the res.istance to brown blight total nitrogen and tannin content in suminer, the reduced form vitamin C content in winter, and regeneration power in cutting. Triploid varieties was more hardy to cold, and some of them had extremely early growing spring bud. The water reserving ability of triploid leaves isolated from stem was greater than that of diploids in September, but the relation changed to be indifferent. in December. 4. Generally triploid fertility was very low but the difference of fertility between each triploid variety was noticed. The pollen grains of triploids showed high sterility. 5. From progenies of triploids, we discovered one aneuploid plant (2n=44). The characters were same like those of triploids and the meio. sis was proceeded abnormally. 6. With colchicine treatment to the growing point of germinated seeds, some tetraploid plants (2ri=60) were obtained. At present, tetraploid plants are growing slowly and they have, dwarf form.

著者

楊 斌 中川 裕志

出版者

人工知能学会

雑誌

人工知能学会全国大会論文集 (ISSN:13479881)

巻号頁・発行日

vol.27, 2013

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Numerous methods have been proposed for privacy-preserving data mining (PPDM). Most of these methods are based on an assumption that semi-honest is and collusion is not present. In other words, some parties may collude and share their record to deduce the private information of other parties. We considered a general problem in this issue - multiparty secure computation of functions on secure summations of data spreading around multiple parties. In order to solve above collustion problem, we have proposed a secure computation method that entails a high level of collusion-resistance. Unfortunately, the private inputs of some parties may be infered because unnecessary information is disclosed in the process of this method. In this paper, we will improve this method, so that the final result is directly computed without any intermediate information being revealed. Moreover, this method can be used to securely compute almost any kind of function on secure cummations.

著者

古賀 信吉 鈴木 康通 中越 裕三 田中 春彦

出版者

社団法人日本化学会

雑誌

化学と教育 (ISSN:03862151)

巻号頁・発行日

vol.51, no.9, pp.560-563, 2003-09-20

参考文献数

10

著者

Di ZHANG Reina FUJIWARA Toshie ISERI Shotaro NAGAHAMA Kei KAKISHIMA Masatoshi KAMATA Manabu MOCHIZUKI Takayuki NAKAGAWA Nobuo SASAKI Ryohei NISHIMURA

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.75, no.5, pp.663-666, 2013 (Released:2013-05-31)

参考文献数

16

被引用文献数

3 10

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The epidural distribution of iohexol (0.2 ml/kg) administered at thoracic vertebrae (Thoracic group) and lumbar vertebrae (Lumbar group) was compared by computed tomographic (CT) epidurography in dogs. The total spread of iohexol was similar between the 2 groups upon reaching a similar cranial level. The maximal CT values were higher at the C7/T1 and T4/T5 levels in Thoracic group, but they were higher at the T13/L1 and L4/L5 levels in Lumbar group (P<0.05). This result suggests that the distribution pattern of the drug administered epidurally at thoracic vertebrae and lumbar vertebrae is different in dogs.

著者

Takaharu ITAMI Kodai KAWASE Naomichi TAMARU Tomohito ISHIZUKA Jun TAMURA Kenjirou MIYOSHI Mohammed A. UMAR Hiroki INOUE Kazuto YAMASHITA

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.75, no.5, pp.613-618, 2013 (Released:2013-05-31)

参考文献数

30

被引用文献数

5 14

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Tramadol is an atypical opioid analgesic widely used in small animal practice. This study was designed to determine the effect of a single intravenous (IV) dose of tramadol on the minimum alveolar concentration (MAC) of sevoflurane in dogs. Six beagle dogs were anesthetized twice to determine the sevoflurane MAC with or without an administration of tramadol (4 mg/kg, IV) at 7 days interval. The sevoflurane MAC was determined using a tail clamp method in each dog ventilated with positive pressure ventilation. The tramadol administration produced a significant reduction in the sevoflurane MAC by 22.3 ± 12.2% (1.44 ± 0.28% with tramadol versus 1.86 ± 0.30% without tramadol, P=0.010). This MAC reduction had been determined from 122 ± 19 to 180 ± 41 min following the tramadol administration. During this period, the plasma concentrations of tramadol and its metabolite, O-desmethyltramadol (M1), decreased from 429 ± 64 to 332 ± 55 ng/ml and from 136 ± 24 to 114 ± 68 ng/ml, respectively, but these changes were not statistically significant. There was no significant difference in heart rate, mean arterial blood pressure and SpO2 between the control and tramadol treatment. The dogs that received tramadol treatment sometimes breathed spontaneously. Therefore, their respiratory rates significantly increased, and PETCO2 decreased during the MAC determination. In conclusion, the single IV dose of tramadol produced a significant reduction in the sevoflurane MAC in dogs.

著者

Hitoshi HATAI Mitsuru IBA Daisuke KOJIMA Chun-Ho PARK Yasuhiko TSUCHIDA Toshifumi OYAMADA

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.75, no.5, pp.639-641, 2013 (Released:2013-05-31)

参考文献数

13

被引用文献数

1 6

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A 13-year-old castrated male Labrador retriever dog presented with a mass caudal to the first molar of his left mandible. Although the tumor was excised, a recurrent tumor was detected one month later and resected. Both tumors displayed invasive growth and were composed of neoplastic proliferation arranged in irregular lobules, nests and cords continuous with mucosal epithelium. The most prominent feature of the tumors was the presence of many proliferating spindle cells admixed with palisading basal-like cells, acanthocytes and stellate cells. In immunohistochemical examinations, the spindle cells were found to be positive for vimentin; cytokeratin AE1/AE3, 5/6, 14 and 19; and p63. The other neoplastic cells were positive for all of these markers shown above except vimentin. Based on these findings, the tumors were diagnosed as spindle cell ameloblastic carcinoma.

著者

Hiroko MIZOOKU Yumiko KAGAWA Kazuya MATSUDA Minoru OKAMOTO Hiroyuki TANIYAMA

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.75, no.5, pp.597-603, 2013 (Released:2013-05-31)

参考文献数

35

被引用文献数

6

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Histological and immunohistochemical evaluations of lobular dissecting hepatitis (LDH) were performed in nine American cocker spaniel dogs. Histological examination showed diffuse fibrosis with weak inflammatory reaction of extensive neutrophils, macrophages, lymphocytes and plasma cells. Immunohistochemical examination revealed that the myofibroblastic cells positive for anti-α-smooth muscle actin and anti-vimentin antibodies produced reticular and collagen fibers and brought about the dissection of hepatic cords and diffuse disappearance of hepatocytes. Reticular fibers invading between hepatocytes and the surrounding small group of hepatocytes were strongly positive for anti-collagen type III and anti-collagen type IV antibodies. The positivity to anti-fibronectin and anti-laminin antibodies was frequently continuous on the basement membrane of the sinusoids of the remaining hepatic cords and between the hepatocytes. Positive findings for anti-E-cadherin antibody were not observed between the hepatocytes showing positive findings for anti-collagen type III and anti-collagen type IV antibodies. These results may explain the expression of fibronectin and laminin that occurs prior to the invasion of reticular fibers between hepatocytes. The present study further suggests that expression of an extracellular matrix mainly containing fibronectin and laminin between the hepatocytes and proliferation of collagen fibers and reticular fibers have a major role in the rupture of the hepatic cords and disappearance of hepatocytes.

著者

Ikuo INOUE Sanae SHIBATA Tsuneo FUKATA

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.75, no.5, pp.657-658, 2013 (Released:2013-05-31)

参考文献数

20

被引用文献数

1 4

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The aim of this study was to determine the antimicrobial resistance of Escherichia coli isolated from the uteri of bitches with pyometra, and 38 E. coli isolates were used. The antimicrobials used were ampicillin (ABPC), amoxicillin/clavulanic acid, gentamicin, minocycline, cefazolin, levofloxacin (LVFX), trimethoprim-sulfamethoxazole (ST) and fosfomycin (FOM). Resistance to ABPC occurred most frequently, followed by LVFX and ST. Multi-drug resistance, defined as resistance against 3 or more classes of antimicrobials, was found in 23.7% of all isolates. Nine out of 13 resistant strains were multi-drug resistant, but no strain was found to be resistant to FOM. This suggests that FOM should be administered for E. coli from pyometra.

著者

田中大秀 著

出版者

松屋平兵衛

巻号頁・発行日

vol.巻第1, 1895

著者

二松学舎 編

出版者

松雲堂書店

巻号頁・発行日

1930

著者

中村 政隆

出版者

公益社団法人日本オペレーションズ・リサーチ学会

雑誌

日本オペレーションズ・リサーチ学会秋季研究発表会アブストラクト集

巻号頁・発行日

vol.1999, pp.190-191, 1999-09-20