著者

Zhen-Guang Li Zhan-Cai Yu Yong-Peng Yu Dao-Zhen Wang Wei-Ping Ju Qi-Zhuan Wu

出版者

Japan Brain Science society

雑誌

脳科学誌 (ISSN:13415301)

巻号頁・発行日

vol.37, pp.35-46, 2011 (Released:2017-06-01)

参考文献数

32

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Lysophosphatidic acid (LPA) is released from activated platelets. Statins are the commonly used anti-atherosclerotic drug. The purpose of this study is to observe whether atorvastatin could decrease the plasma LPA levels in ischemic stroke patients. A total of 386 subjects, including the 247 ischemic stroke cases and 139 healthy controls, were enrolled in this study. The 247 ischemic stroke cases were divided into Group A (n=109) and Group B (n=138) who had and had not received atorvastatin treatment before a stroke respectively. The plasma LPA levels of all the subjects were measured using chromatography. There was significant diffidence in the LPA levels between cases and controls (3.22±1.51μmol/L vs. 1.83±1.07μmol/L, p<0.01). The plasma LPA level in Group A was lower than that of Group B (2.66±1.23umol/L vs. 3.83±1.14umol/L, p<0.01). Atorvastatin (20mg/d) significantly reduced LPA levels in ischemic stroke patients (n=138) compared with that before atorvastatin administration (1.96±0.87μmol/L vs. 3.83±1.14μmol/L, p<0.01). However, the LPA levels re-elevated after atorvastatin withdrawl for one month. Atorvastatin could decrease the plasma LPA levels in patients with ischemic stroke, which providing a better understanding of how statins protect against ischemic stroke. It is plausible to speculate that statins might have an effect of anti platelet activation.

著者

Geert W. Schmid-Schonbein

出版者

Japan Brain Science society

雑誌

脳科学誌 (ISSN:13415301)

巻号頁・発行日

vol.38, pp.4-5, 2012-03-30 (Released:2017-06-01)

著者

Eriko Suwa Kiyomi Kondo-Ikemura Saeko Sakai

出版者

Japan Brain Science society

雑誌

脳科学誌 (ISSN:13415301)

巻号頁・発行日

vol.38, pp.6-20, 2012-03-30 (Released:2017-06-01)

参考文献数

44

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From the attachment theory point of view, a child internalizes the representations of self, parent, and relationships through his or her early interaction with the caregiver, and those representations construct an Internal Working Model through which external information is processed. Those representations, that is, Internal Working Models, become the prototype for the pattern of a child's behaviour and relationship with others. In order for children to develop a healthy Internal Working Model, emotional availability of the caregiver, rather than physical availability, is essential. The study focused on 21 non-clinical Japanese preschoolers aged 4 to 5 years, and explored the link between the maternal emotional availability and the child's parental representations. The mother-child interactions in a semi-structural setting were observed, and maternal emotional availability was evaluated with the Emotional Availability Scales (4^<th>.Ed.). Parental representations in the child's mind were assessed through Story Stem Assessment Profile, a story completion task using doll play. It was found that children whose mothers' levels of emotional availability are high have more positive parental representations and less negative representations than the children whose mothers' levels of emotional availability are low. This consistent link between maternal emotional availability and children's parental representations indirectly supports the idea that non-clinical children construct representations of parents consistent with their experiences with their mothers. Moreover, this research implies the usefulness of systematic analysis of children's play and story in order to assess their subjective internal world.

著者

Zhao-qiang Zhang Xiao Sun Bing-xiang Wang Yan-ling Zhang

出版者

Japan Brain Science society

雑誌

脳科学誌 (ISSN:13415301)

巻号頁・発行日

vol.36, pp.50-60, 2011-03-30 (Released:2017-06-01)

参考文献数

10

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Objective Modeling a surgery hypertensive rat model, observe the changes of the expression of ACE and ACE2 in various groups, thus for further research of the pathogenesis of hypertension. Methods Twenty-eight Sprague- Dawley rats were used, which were divided randomly into four groups. One group served as control (n=7), others as hypertensive group (n=7), enalapril group [n=7,15mg/(kg・d)] and losartan group [n=7,15mg/(kg・d)]. All rats were operated as surgery hypertension except rats of control group. Renal artery was ligated. Enalapril and losartan were used as treatments of rats of enalapril group and losartan group after surgery. Blood pressure of rats was measured by arteria caudilis uninjured. The expression of renal ACE and ACE2 mRNA were measured by RT-PCR. The expression of renal ACE and ACE2 protein were measured by immunohistochemistry. Results Blood pressure of rats was increased after operation. The expression of ACE and ACE2 mRNA and protein in various groups were different. The expression of ACE mRNA and protein of Hypertensive group were higher than others. The expression of ACE2 mRNA and protein of losartan group were higher than others. Conclusion Model of surgery hypertensive rats were success by the ligation of renal artery. It's a Simple, reliable and cheap method of hypertensive rat model. The imbalance between the expression of ACE and ACE2 is one of the important roles of pathogenesis of hypertension.

著者

Arshin Adib-Moghaddam

出版者

独立行政法人 日本貿易振興機構アジア経済研究所

雑誌

中東レビュー (ISSN:21884595)

巻号頁・発行日

vol.7, pp.51-64, 2020 (Released:2020-03-27)

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「サイコ・ナショナリズム」は、現在の中東地域において不安定要因を形成する主要な要因であり、それは排他的な国民意識の核となる集団的自己意識の半ば意図的に捏造された発明品である。本論は中東イスラーム世界における哲学的議論の豊かな蓄積―イブン・ハルドゥーンの政治学的・社会学的考察を含む―の上に、近年盛んに行われているアイデンティティー政治学の宗派主義・部族主義的な分析枠組みの脱構築を意図している。本論ではまずアラブ世界およびイラン世界における「想像的共同体」の具体的な構成要素に検討を加えたうえ、とりわけ中東地域においては人間集団間の長期的な混交と相互依存構築という歴史的な経験を踏まえた理性的な対話・交渉による関係の構築が地域的平和の実現のための不可欠の要件であることを確認する。

著者

Arshin Adib-Moghaddam

出版者

独立行政法人 日本貿易振興機構アジア経済研究所

雑誌

中東レビュー (ISSN:21884595)

巻号頁・発行日

vol.5, pp.49-56, 2018 (Released:2019-03-15)

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本稿は今年8月に発足したロウハーニー第二期政権のとりわけ外交政策を1979年以来のイラン・イスラーム共和国政権の政治的展開の帰結として位置づけることを目的とするものである。革命後のイランは現在に至るまで西側諸国の新自由主義的な経済政策に対して一定の距離を堅持してきた。またパレスチナ問題に対する明確な対パレスチナ支持の姿勢も今後長期にわたりその基本線が変わることはないだろう。だがそのニュアンスについて可変的であることは、イスラエルを「シオニスト国家」と呼ぶことを慎重に回避し続けるザリーフ外相の発言などからも伺える。米国における2017年の年初のトランプ政権の発足にも拘らず、イランとP5+1の間のJCPOAがトランプ大統領によって破棄されるという可能性は極めて低い。だが革命以来のイランの非同盟諸国重視の外交姿勢は現在に至るまで続いており、南米のベネズエラ・ボリビア・ブラジル・キューバといった諸国との緊密な関係もロウハーニー政権においても維持されることは明白である。革命後のイラン外交は決してシーア派重視あるいはイスラーム重視に傾斜することなく、それはあくまでも国益重視の姿勢に貫かれてきた。政策的な選択についても2009年以降は国際社会との協調の方向に大きく転換しているが、ただそれが西側と共通の人権擁護の理念に基づいていないという問題は依然としてある。いずれにしても5月の選挙の結果、ロウハーニー政権は政策的な合理性・優位性について国民の信託を受けたものと理解すべきである。ある種の市民社会が育ちつつあるイランの国内政治において、いわゆる「保守派対改革派」の単純な図式はますます意味を失いつつある。イランは今後将来的に非イデオロギー的・非革命的な通常の国家として、日本を含む国際社会の一員としての道を歩むことが期待される。(文責・鈴木均)

著者

Luis Alberto Santa-María Juárez

出版者

Society for Andean and Amazonian Studies

雑誌

アンデス・アマゾン研究 (ISSN:24340634)

巻号頁・発行日

vol.4, pp.23-37, 2020-12-20 (Released:2022-04-06)

著者

Meraj Alam Mukesh-Kumar Mishra Tatiana-Vladimirovna Kaulina Talat Ahmad Ashwini-Kumar Choudhary

出版者

GEOCHEMICAL SOCIETY OF JAPAN

雑誌

GEOCHEMICAL JOURNAL (ISSN:00167002)

巻号頁・発行日

pp.GJ22016, (Released:2022-09-27)

被引用文献数

5

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The Central Indian Tectonic Zone (CITZ) is major E-W trending suture zone between Northern and Southern Indian crustal blocks. The southern portion of the CITZ comprises three litho-tectonic units: Tirodi Gneissic Complex (TGC), Sausar Mobile Belt (SMB) and Bhandara-Balaghat Granulite Belt (BBGB). Elemental and isotopic data are used to constrain the genesis of granitoids and their protoliths, which may help us to understand the Proterozoic crustal evolution in CITZ. Geochemical and isotopic results are consistent with previous studies that these granitoid plutons are linked to the felsic magmatism of the Columbian crustal assembly in India, North America and North China. Granitoids varies from tonalite to granite, alkalic to calcic, metaluminous to peraluminous composition. Normalized elemental ratios of La/Sm, La/Yb, La/Lu, and Gd/Yb depict variable LREE enrichments and varying degrees of partial melting of heterogeneous crustal/lithospheric sources. The studied rocks are characterized by positive anomalies for Pb and negative anomalies for Nb, Sr, P, Ti, which indicate the influence of subduction-zone fluids in the source regions. Negative anomalies for K, Sr, and Ti for SMB and BBGB granitoids may also be attributed to K-feldspar, plagioclase, and Fe-Ti oxide fractionation. However, TGC porphyritic leucogranites display K, Ba and Eu positive anomalies, probably related to the accumulation of K-feldspar phenocrysts. Nd-Sr data presents initial ratios of 143Nd/144Nd t=1.6 Ga ranges between 0.509961 and 0.510300; εNd t=1.6 Ga ranges from -5.3 to -11.9 with TDM ages ranging from 2.20 to 2.78Ga for TGC granitoid. The ratios of 143Nd/144Nd t=1.6 Ga ranges between 0.510232 and 0.510985; εNd t=1.6 Ga ranges from +0.2 to +8.2 and TDM ages varies from 1.5 to 3.0 Ga. The initial 87Sr/86Sr t=1.6 Ga ratios ranges between 0.699834 and 0.797151 for SMB granitoid. However, BBGB granitoids show the ratios of 143Nd/144Nd t=1.6 Ga ranges between 0.509752- and 0.510910; εNd t=1.6 Ga ranges from +6.7 to -16, and TDM ages range from 1.51 to 3.29 Ga. The initial 87Sr/86Sr (t=1.6 Ga) ratios varies between 0.705096 and 0.717440. These ranges of εNd (t) and TDM values possibly indicate their derivation from enriched and heterogeneous crustal/lithospheric sources, and minor components from depleted lithospheric sources.

著者

Masahiro Endo Kei Fujiwara Syougo Hamada Satoshi Murata Shin-ichiro M Nomura

出版者

The Biophysical Society of Japan General Incorporated Association

雑誌

生物物理 (ISSN:05824052)

巻号頁・発行日

vol.52, no.supplement, pp.S107, 2012-08-15 (Released:2017-05-01)

著者

Jean-Baptiste Joinet Thomas Seiller

出版者

The Philosophy of Science Society, Japan

雑誌

科学哲学 (ISSN:02893428)

巻号頁・発行日

vol.53, no.2, pp.65-93, 2021-03-31 (Released:2021-03-31)

参考文献数

38

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At the end of the 19th century, the Peano School elaborated its famous theory of “definitions by abstraction”. Two decades later,Hermann Weyl elaborated a generalization of the former, termed “creative definitions”, capable of covering various cases of ideal elements (Peano’s abstracta being among them). If the Peano School proposal eventually appeared to be based on the nowadays standard classificatory process of quotienting a set by an equivalence, Weyl’s proposal still lacks a set-theoretical, classificatory interpretation. In this paper,we define and investigate the notion of relational indiscernibility (upon which Weyl’s creative definitions are based) and show that a bridge from the concept of indiscernibility to the notion of type (sets closed by bi-orthogonal) may be built from the observation that individuals are indiscernible exactly when they belong to exactly the same types. In the last part, we investigate some philosophical consequences of those observations concerning the theory of abstraction.

著者

Chih-Hsiang Chang Yasushi Ishihama

出版者

Japanese Proteomics Society

雑誌

Journal of Proteome Data and Methods (ISSN:24346454)

巻号頁・発行日

vol.4, pp.3, 2022 (Released:2022-09-17)

参考文献数

12

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Trapped ion mobility spectrometry (TIMS) has been considered as a promising tool in structural biology, proteomics and many other analytical applications. This dataset consists of cell lysates digested with each of seven proteases (trypsin, LysargiNase, Lys-C, Lys-N, Glu-C, Asp-N, and chymotrypsin), fractionated using SCX-StageTip, and analyzed by nanoLC/TIMS/Q/TOF. The data accompanying this paper have been deposited to jPOST with the identifiers JPST000959, JPST001017 and JPST001176.

著者

中島 恭子 Burke-Gaffney Brian

出版者

長崎総合科学大学附属図書館運営委員会

雑誌

長崎総合科学大学紀要 = Bulletin of the Nagasaki Institute of Applied Science (ISSN:24239976)

巻号頁・発行日

vol.56, no.2, pp.65-76, 2017-02-03

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In October 1860, little more than a year after the opening of Japan’s doors in the wake of the Ansei Five-Power Treaties, Nagasaki British Consul George S. Morrison engaged Swiss photographer Pierre Rossier to take several photographs of Nagasaki Harbor, including the proposed site of the Nagasaki Foreign Settlement. The first taken in Japan, the panoramic photographs provide invaluable insights into the scenery of Nagasaki as it emerged from the long period of national isolation. This paper presents the photographs and the entire letter sent by Morrison to British authorities describing the scenes captured in the photographs. For the first time, it also provides a concise Japanese translation of the letter, a foothold for further research in the field.

著者

Sabina Šturm Tanja Švara Ellinor Spörndly-Nees Vesna Cerkvenik-Flajs Mitja Gombač Anna-Luisa Weber Klaus Weber

出版者

JAPANESE SOCIETY OF TOXICOLOGIC PATHOLOGY

雑誌

Journal of Toxicologic Pathology (ISSN:09149198)

巻号頁・発行日

vol.34, no.4, pp.331-338, 2021 (Released:2021-10-01)

参考文献数

34

被引用文献数

2

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Testicular histopathology is considered the most sensitive and reliable method to detect the effects of chemicals on sperm production. To carry out a sensitive examination of testicular histopathology and interpret the changes require knowledge of spermatogenic stages. Spermatogenic staging based on acrosome development during spermiogenesis is conventionally performed in animal species routinely used for research and toxicity testing. In contrast, small ruminants, such as sheep and goats, are rarely used as animal models to evaluate toxicity in male reproductive organs. To the best of our knowledge, a comparable spermatogenic staging system in rams has not yet been fully characterised. Hence, this study aimed to adapt the existing spermatogenic staging based on acrosome development in bull testes to fit the seminiferous epithelium cycle of ram testes. The results show that spermatogenic staging based on acrosome development in bull testes can, with slight modifications, be efficiently used for the staging of ram testes.

著者

Riho SHIKANO Koichi OHNO Takuro NAGAHARA Itsuma NAGAO Hiroto TOYODA Taisuke NAKAGAWA Yuko GOTO-KOSHINO James K. CHAMBERS Hirotaka TOMIYASU Hajime TSUJIMOTO

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.22-0126, (Released:2022-09-08)

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The associations of diet compositions with mucin secretion in gallbladder have not been investigated in dogs. This study aimed to examine the effects of a low-carbohydrate diet (LC) and a low-fat diet (LF) on bile mucin concentration and composition of gallbladder bile in six clinically healthy beagle dogs. After feeding of both diets, the bile mucin concentration was significantly decreased. In addition, there were significant decreases in the concentrations of taurochenodeoxycholic acid in bile, which is considered to promote mucin secretion, after feeding of both diets. The present study suggested that the proportions of carbohydrate and fat in diet affect the composition of gallbladder bile in dogs.

著者

Yu-Liang Lin Cheng-Chien Kuo Chung-Ming Leng Chein-Chung Sun

出版者

The Institute of Electronics, Information and Communication Engineers

雑誌

IEICE Electronics Express (ISSN:13492543)

巻号頁・発行日

vol.19, no.16, pp.20220178, 2022-08-25 (Released:2022-08-25)

参考文献数

32

被引用文献数

2

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A LED driver with a high Power Factor (PF) under universal AC voltage input is investigated in this paper. The AC/DC buck converter with novel dual sampling loop feedback control is adopted to implement the LED driver application. When the main switch is on interval, the control loop does peak current sampling. When main switch is off interval, the control loop does average current sampling. Two control sampling loops are superimposed to regulate the main switch to adapt the AC input voltage and load alteration. Such a scheme can keep the characteristic of peak current control of fast response and avoid the control delay to bring about over current for damage LED. Compared with the conventional peak current control method, the proposed design does not need zero current detect winding and multiplier. Therefore, the circuit architecture of the proposed driver is cheaper. The proposed driver is applied to a 12W LED to analyze the operational principles and verify the practicality.

著者

李 徳周 Deok-Joo Rhie

出版者

基督教研究会

雑誌

基督教研究 = Kirisutokyo Kenkyu (Studies in Christianity) (ISSN:03873080)

巻号頁・発行日

vol.73, no.2, pp.1-32, 2011-12-05

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同志社大学神学部と韓国教会の関係は日本組合教会の朝鮮教化の展開から開始された。しかし1919年三・一独立運動の後、組合教会を背景にする留学生は減り、様々な教派あるいは神学的な背景を持つ神学生または牧会者たちが留学した。1920年代から彼らは同志社の自由主義的な雰囲気の中で、カール・バルトの新正統主義神学、脱西欧的日本神学、実践的なキリスト教社会主義などを学んだ。50余りの留学生たちは帰国後、彼らは韓国の教会、進歩的神学、教育、社会運動等様々な分野で活躍した。

著者

Alexis Mojica Bolívar Duarte Fidedigna Vergara Milagros Pinto-Núñez Reinhardt Pinzón José Pérez María Gabriela Castrellón Carlos A. Ho Margie Gómez

出版者

Japan Society of Hydrology and Water Resources (JSHWR) / Japanese Association of Groundwater Hydrology (JAGH) / Japanese Association of Hydrological Sciences (JAHS) / Japanese Society of Physical Hydrology (JSPH)

雑誌

Hydrological Research Letters (ISSN:18823416)

巻号頁・発行日

vol.16, no.1, pp.18-24, 2022 (Released:2022-03-11)

参考文献数

29

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Monitoring and quantifying hydrological flows in the vadose zone is complicated to analyze due to the effects of rainfall in the tropics, the dynamic interactions among rains, the vegetation layer, moisture in the soil, and the entire regolith. Quantifying subsurface hydrological flows at specific scales and high resolution presents further difficulties. To overcome these issues, resistivity methods can play an important role. This paper examines the results of gravimetric moisture content monitoring in the Panamanian tropics through time-lapse electrical resistivity tomography analysis. Changes in the electrical properties of soil were quantified through six tomographic tests performed between February 2012 and March 2013 along with a profile. Significant changes in resistivity were identified between February (dry season) and May, and August and October (rainy season), with negative percentages (–60%) indicating the effects of rain infiltration at the surface and positive percentages (60%) linked to moisture absorption in the soil, electrode relocation for each test or inversion processes. Additional laboratory analyses of soil samples were carried out to obtain gravimetric moisture content tomograms. The changes of this parameter in the subsurface horizons, and the percentage differences in the calculated resistivity values, are helpful for determining the impact of rain on the soils.

著者

Arthur W.J.G. Ord-Hume illustrated by the author

出版者

Schiffer

巻号頁・発行日

1995

著者

Arthur W.J.G. Ord-Hume illustrated by the author

出版者

University College Cardiff Press

巻号頁・発行日

1982

著者

by Arthur W.J.G. Ord-Hume illustrated by the author

出版者

Schiffer Pub.

巻号頁・発行日

2007