著者

Arthur W. J. G. Ord-Hume

出版者

St. Martin's Press

巻号頁・発行日

1980

著者

Arthur W.J.G. Ord-Hume

出版者

Schiffer Pub.

巻号頁・発行日

2004

著者

Arthur W.J.G. Ord-Hume illustrated by the author

巻号頁・発行日

1983

著者

Arthur W.J.G. Ord-Hume illustrated by the author

出版者

George Allen & Unwin

巻号頁・発行日

1984

著者

Arthur W.J.G. Ord-Hume with diagrams by the author

出版者

Mayfield Books

巻号頁・発行日

2005

著者

Arthur W.J.G. Ord-Hume

出版者

George Allen & Unwin

巻号頁・発行日

1977

著者

Chun-Ka Wong Hayes Kam-Hei Luk Wing-Hon Lai Yee-Man Lau Ricky Ruiqi Zhang Antonio Cheuk-Pui Wong George Chi-Shing Lo Kwok-Hung Chan Ivan Fan-Ngai Hung Hung-Fat Tse Patrick Chiu-Yat Woo Susanna Kar-Pui Lau Chung-Wah Siu

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

vol.84, no.11, pp.2027-2031, 2020-10-23 (Released:2020-10-23)

参考文献数

10

被引用文献数

15 33

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Background:SARS-CoV-2 infection is associated with myocardial injury, but there is a paucity of experimental platforms for the condition.Methods and Results:Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) infected by SARS-CoV-2 for 3 days ceased beating and exhibited cytopathogenic changes with reduced viability. Active viral replication was evidenced by an increase in supernatant SARS-CoV-2 and the presence of SARS-CoV-2 nucleocaspid protein within hiPSC-CMs. Expressions of BNP, CXCL1, CXCL2, IL-6, IL-8 and TNF-α were upregulated, while ACE2 was downregulated.Conclusions:Our hiPSC-CM-based in-vitro SARS-CoV-2 myocarditis model recapitulated the cytopathogenic effects and cytokine/chemokine response. It could be exploited as a drug screening platform.

著者

Yu Takahashi Takayoshi Toba Hiromasa Otake Hiroyuki Kawamori Hidekazu Tanaka Ken-ichi Hirata

出版者

The Japanese Circulation Society

雑誌

Circulation Reports (ISSN:24340790)

巻号頁・発行日

vol.4, no.8, pp.390-391, 2022-08-10 (Released:2022-08-10)

参考文献数

1

著者

熊倉 裕子 辛 銀眞 杉山 充 高橋 佳子 六笠 恵美子 Liu Chia-I 和田 晃子

出版者

早稲田大学大学院日本語教育研究科

雑誌

早稲田大学日本語教育実践研究 (ISSN:13499084)

巻号頁・発行日

vol.創刊号, pp.149-158, 2004-12

著者

Masaki Yoshioka Keisei Kosaki Masahiro Matsui Shoya Mori Natsumi Nishitani Chie Saito Kunihiro Yamagata Makoto Kuro-o Seiji Maeda

出版者

The Japan Endocrine Society

雑誌

Endocrine Journal (ISSN:09188959)

巻号頁・発行日

pp.EJ22-0063, (Released:2022-09-03)

被引用文献数

3

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Fibroblast growth factor-23 (FGF23) is a phosphaturic hormone secreted by the bone in response to dietary phosphate intake. Since the phosphate content in the diet correlates with the protein content, both plant- and animal-based protein intake can increase the serum FGF23 level. However, a higher percentage of energy from plant protein than from animal protein is associated with a lower serum FGF23 level in patients with chronic kidney disease (CKD) in the United States. Since dietary habits differ between Asian and Western populations, we performed a cross-sectional study to determine the association between the percentages of energy from plant and animal proteins and the serum FGF23 level in Japanese CKD patients. In 107 non-dialysis CKD patients (age: 66 ± 9 years; estimated glomerular filtration rate: 56 ± 21 mL/min/1.73 m2), the percentages of energy from plant and animal proteins were assessed using a food frequency questionnaire based on food groups. Venous blood samples were used to measure the serum FGF23, phosphate, 1,25-dihydroxyvitamin D, and intact parathyroid hormone levels. The percentages of energy from plant and animal proteins showed a negative and positive association, respectively, with the serum FGF23 level. Furthermore, isocaloric substitution modeling showed that replacing animal protein with plant protein was associated with a low serum FGF23 level. Our findings suggest that encouraging diets with high plant protein level may prevent an increase in the serum FGF23 level in Japanese CKD patients.

著者

Yun-Shan Li Kazuaki Kawai Hiroshi Kasai

出版者

The Japanese Environmental Mutagen and Genome Society

雑誌

Genes and Environment (ISSN:18807046)

巻号頁・発行日

vol.29, no.3, pp.128-132, 2007 (Released:2007-09-12)

参考文献数

24

被引用文献数

7 6

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To clarify the in vivo genotoxic potential of dietary style, the amounts of 8-hydroxydeoxyguanosine (8-OH-dG), a marker of oxidative DNA damage, were determined by a high-performance liquid chromatography system coupled to an electrochemical detector (HPLC-ECD) in the urine of female mice to which a vitamin-deficient diet (for two months) and a sweet beverage (for two weeks) were administered. The urinary 8-OH-dG levels were clearly increased in these studies. In the vitamin-deficient diet experiment, the urinary 8-OH-dG levels were increased to 1.2-fold and 1.4-fold after one month and two months, respectively. When mice were given a commercially available sweet beverage instead of water for two weeks, the urinary 8-OH-dG was increased to 1.4-fold. In the sweet beverage experiment, significant increases of the volume consumed per day were observed, as compared to the control group (water). Although the total caloric intake per day was not remarkably different between the sweet beverage- and control-group, the mice in the sweet beverage group obtained a higher ratio of calories from sugar components. These results indicated that the elevation of oxidative stress could be caused by the prolonged intake of an unbalanced diet, such as a vitamin-deficient diet or one including sweet beverages.

著者

Kazumasa Oshima Masataka Sakamoto Kazumasa Morita Kenichi Kon Ken-ichi Shimizu Tsuyoshi Yamamoto Masahiro Kishida Shigeo Satokawa

出版者

The Society of Chemical Engineers, Japan

雑誌

JOURNAL OF CHEMICAL ENGINEERING OF JAPAN (ISSN:00219592)

巻号頁・発行日

vol.55, no.7, pp.243-247, 2022-07-20 (Released:2022-07-20)

参考文献数

17

被引用文献数

2

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The effective utilization of carbon fibers recovered during the thermal decomposition recycling of carbon-fiber-reinforced plastic (CFRP) was investigated. Carbon fibers have a uniform diameter and a suitable size for the use as a combustion catalyst for particulate matter (PM). Thus, in this study, carbon fibers were used as a template to synthesize hollow-form LaNiO3 perovskite-type oxide via the precursor accumulation method. The calcination temperature was lowered by the internal heat supply from the combustion of the carbon template. Hollow-form LaNiO3 exhibited the same chemical properties as LaNiO3 prepared via the common sol–gel method. The morphology of the hollow form decreased the bulk density of the catalyst, resulting in enhanced contact with PM and, consequently, high PM combustion efficiency.

著者

Takashi KAMEDA Shunya OKA Jun-ichi IGAWA Makoto SAKAMOTO Kazuto TERADA

出版者

The Japanese Society for Dental Materials and Devices

雑誌

Dental Materials Journal (ISSN:02874547)

巻号頁・発行日

vol.41, no.1, pp.167-183, 2022-01-25 (Released:2022-02-01)

参考文献数

26

被引用文献数

2

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Coronavirus disease pandemic has led to a shortage of disinfectant alcohol (DA; 76.9–81.4% ethanol solution) in Japan. This study investigated the availability of hypochlorous acid (HA) as an alternative disinfectant to DA in clinical environment. HA is a safe and economical disinfectant with a broad antibacterial spectrum and low risk of hand irritation, which is used worldwide. In this study, HA and sodium hypochlorite solution (SH) were degraded over time and the degradation was accelerated by temperature and lighting. Results of bactericidal effects of HA revealed that the realistic effective concentration should be 200 ppm. Compared with DA, the dental carbon steel burs were more severely rusted by SH and HA. These results indicated that high concentration of HA generated on-site could be an effective and safe disinfectant for use immediately after generation with consideration of object materials in clinical environment, as an alternative to DA.

著者

朔 啓二郎 三浦 伸一郎 瀬川 波子 野田 慶太 中嶋 恵美子 西尾 美登里 安永 晋一郎晋一郎 柳瀬 敏彦 SAKU Keijiro MIURA Shin-ichiro OGAWA Masahiro ZHANG Bo NODA Keita NAKASHIMA Emiko NISHIO Midori YASUNAGA Shin'ichiro YANASE Toshihiko

出版者

日本機能性食品医用学会

雑誌

機能性食品と薬理栄養 : 日本機能性食品医用学会認定誌 : Associate journal of Japanese Society for Medical Use of Functional Foods = 機能性食品と薬理栄養 : 日本機能性食品医用学会認定誌 : Associate journal of Japanese Society for Medical Use of Functional Foods (ISSN:13482564)

巻号頁・発行日

vol.10, no.1, pp.367-406, 2016

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第13回日本機能性食品医用学会総会会長講演

著者

Manami MONOBE Kaori EMA Yoshiko TOKUDA Mari MAEDA-YAMAMOTO

出版者

Japan Society for Bioscience, Biotechnology, and Agrochemistry

雑誌

Bioscience, Biotechnology, and Biochemistry (ISSN:09168451)

巻号頁・発行日

vol.74, no.12, pp.2501-2503, 2010-12-23 (Released:2010-12-23)

参考文献数

12

被引用文献数

19

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We found that the epigallocatechin gallate (EGCG)/epigallocatechin (EGC) ratio in a green tea (Camellia sinensis L.) extract was affected by the extraction temperature. The EGCG/EGC ratio in the 4 °C extract was around 1:3-4, whereas in the 100 °C extract, it was around 1:0.7. Oral administration of the mixture with a high EGC ratio (1:2-3 = EGCG/EGC) resulted in greater IgA production by murine Peyer’s patch cells.

著者

Pei-lin Lu John F. Hodes Xu Zheng Xing-yue Hu

出版者

The Japanese Society of Internal Medicine

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

pp.4516-20, (Released:2020-06-30)

参考文献数

75

被引用文献数

5 16

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Objective Reversible Splenial Lesion Syndrome (RESLES) is a clinical radiological syndrome characterized by a reversible lesion of the splenium of the corpus callosum with a decreased apparent diffusion coefficient (ADC) value. The clinical manifestations of RESLES are diverse. Methods Fifteen cases of adult RESLES patients (10 males and 5 females) were retrospectively selected from the radiology system using the key word "corpus callosum" at a university-affiliated tertiary care hospital between May 1, 2015 and Dec 31, 2019. The possible precipitating factors, clinicoradiological findings and modified Rankin Scale (mRS) on follow-up were then analyzed. Results The patient ages ranged from 22 to 53 years old. The mean age was 34 years old. The most common neurological symptoms included headache (3/15), dizziness (3/15), first onset of seizure (3/15), paroxysmal blurred vision (2/15), vertigo (2/15), amnesia (2/15), and confused consciousness without seizure (2/15), followed by drowsiness (1/15), paresthesia (1/15), dysmetria (1/15) and dysarthria (1/15). The precipitating factors included infection, seizure, anti-epileptic treatment with levetiracetam, carbamazepine, valproate, hyperglycemia, hypoglycemia, cerebral venous sinus thrombosis, and rabies vaccine injection prior to the onset of RESLES. All cases were carefully followed up and had excellent prognoses. Conclusion RESLES manifests as variety of symptoms with less specificity and precipitating factors. Paroxysmal blurred vision may be a relatively specific symptom of RESLES. Levetiracetam, carbamazepine or valproate could be the cause of RESLES, exposure to the rabies vaccine could be another predisposing factors for RESLES as well. RESLES type 1 was therefore found to be highly "reversible" with an excellent prognosis.

著者

GUO-CHIANG SHOU TOSHIHIRO ISHIKO

出版者

The Japanese Society of Physical Fitness and Sports Medicine

雑誌

体力科学 (ISSN:0039906X)

巻号頁・発行日

vol.43, no.1, pp.58-65, 1994-02-01 (Released:2010-09-30)

参考文献数

30

被引用文献数

2 2

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The purpose of this study was to compare blood lactate concentration, lactate threshold (LT) and onset of blood lactate accumulation (OBLA) during an incremental bicycle exercise under a hot dry environment with those during the same workload under a thermoneutral environment. Eight unacclimated men performed an incremental test to exhaustion on a cycle ergometer during which the work rate was increased by 30 W every three minutes under thermoneutral (25°C) and hot dry (40°C) environmental conditions. Oxygen consumption (VO2) -pulmonary ventilation (VE), gas exchange measures and earlobe blood samples for lactate analysis were obtained every minute during the test. LT (p<0.05) and OBLA (p<0.01) occurred at significantly lower VO2 under the hot environment than those under the thermoneutral environment. Additionally blood lactate concentration was significantly higher (p<0.05) at each measurement period under the hot environment compared with that under the ther-moneutral environment. The correlation between LT and ventilatory threshold (VT) was not statistically significant under the thermoneutral (r=0.20) and hot dry (r=0.60) environments, These findings demonstrate that the hot dry environment may increase blood lactate concentration more and causes a leftward shift of LT and OBLA. Since blood lactate accumulation during incremental exercise is not considered to be the only factor which mediates VE, VT does not always accurately predict LT.

著者

Won-gyu Yoo

出版者

The Society of Physical Therapy Science

雑誌

Journal of Physical Therapy Science (ISSN:09155287)

巻号頁・発行日

vol.28, no.9, pp.2468-2469, 2016 (Released:2016-09-29)

参考文献数

5

被引用文献数

4 6

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[Purpose] The aim of this study was to compare hamstring-to-quadriceps ratio between the accelerating and decelerating sections for anterior cruciate ligament protection during squat exercise. [Subjects and Methods] Nine asymptomatic males were enrolled in this study. The hamstring (medial part) and quadriceps (rectus femoris) muscle activities during squat exercise were measured, and the squat exercises were classified into two sections (accelerating and decelerating) by using an accelerometer. [Results] The hamstring-to-quadriceps ratio was significantly higher in the decelerating section than in the accelerating section during the squat exercise. [Conclusion] Application of an increasing decelerating section strategy during the squat exercise can prevent damage in patients with a weakened anterior cruciate ligament due to sports activities.

著者

Quoc-Trinh VO Quang-Thang DUONG Minoru OKADA

出版者

The Institute of Electronics, Information and Communication Engineers

雑誌

IEICE TRANSACTIONS on Electronics (ISSN:09168516)

巻号頁・発行日

vol.E105-C, no.8, pp.358-368, 2022-08-01

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This paper proposes constant voltage design based on K-inverter for cooperative inductive power transfer (IPT) where a nearby receiver picks up power and simultaneously cooperates in relaying the signal toward another distant receiver. In a cooperative IPT system, wireless power is fundamentally transferred to the nearby receiver via one K-inverter and to the distant receiver via two K-inverters. By adding one more K-inverter to the nearby receiver, our design is among the simplest methods as it delivers constant output voltage to each receiver via two K-inverters only. Experimental results verify that the proposed cooperative IPT system can stabilize two output voltages against the load variations while attaining high RF-RF efficiency of 90%.

著者

Hyeon-Mi Park Nobukazu Nakasato Teiji Tominaga

出版者

Tohoku University Medical Press

雑誌

The Tohoku Journal of Experimental Medicine (ISSN:00408727)

巻号頁・発行日

vol.226, no.3, pp.207-211, 2012 (Released:2012-02-21)

参考文献数

14

被引用文献数

17 22

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The insula, one of the five cerebral lobes of the brain, is located deep within the brain and lies mainly beneath the temporal lobe. Insular epilepsy can be easily confused and misdiagnosed as temporal lobe epilepsy (TLE) because of the similar clinical symptoms and scalp electroencephalography (EEG) findings due to the insula location and neuronal connections with the temporal lobe. Magnetoencephalography (MEG) has higher sensitivity and spatial resolution than scalp EEG, and thus can often identify epileptic discharges not revealed by scalp EEG. Simultaneous scalp EEG and MEG were performed to detect and localize epileptic discharges in two patients known to have insular epilepsy associated with cavernous angioma in the insula. Epileptic discharges were detected as abnormal spikes in the EEG and MEG findings. In Patient 1, the sources of all MEG spikes detected simultaneously by EEG and MEG (E/M-spikes) were localized in the anterior temporal lobe, similar to TLE. In contrast, the sources of all MEG spikes detected only by MEG (M-spikes) were adjacent to the insular lesion. In Patient 2, the sources of all MEG spikes detected simultaneously by EEG and MEG (E/M-spikes) were localized in the anterior temporal lobe. These findings indicate that MEG allows us to detect insular activity that is undetectable by scalp EEG. In conclusion, simultaneous EEG and MEG are helpful for detecting spikes and obtaining additional information about the epileptic origin and propagation in patients with insular epilepsy.