著者

Christian-H. Heeger Huong-Lan Phan Roza Meyer-Saraei Thomas Fink Vanessa Sciacca Spyridon Liosis Ben Brüggemann Niels Große Bezhad Fahimi Makoto Sano Karl-Heinz Kuck Feifan Ouyang Julia Vogler Charlotte Eitel Roland Richard Tilz

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

pp.CJ-19-0766, (Released:2019-11-09)

参考文献数

29

被引用文献数

22

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Background:Radiofrequency (RF)-based pulmonary vein isolation (PVI) results in a favorable clinical outcome, although its complexity demands a long learning curve. Balloon-based systems have been developed to possibly solve these limitations. The 2nd-generation laser balloon (LB2) offers optimized features for improved tissue contact and visibility. We determined the safety, efficacy and learning curve of the LB2 for PVI.Methods and Results:A total of 45 consecutive patients (89% persistent AF) were prospectively enrolled and divided into 3 groups (T1, T2, T3) of n=15 patients per group. All patients underwent PVI by 2 operators using the LB2. The operators were experienced in RF and cryothermal procedures, but not in laser ablations. A total of 174/177 PVs (98%) were successfully isolated. The median procedure time significantly declined from 132 (114, 158) to 119 (102, 127) and 91 (86, 105) min in T1–3, respectively (P=0.0009). Similarly, the median fluoroscopy time significantly decreased from T1 to T3 (22 (17, 27) vs. 21 (16, 24) vs. 13 (10, 17) min, respectively, P=0.045). Adverse events occurred in 6.7%, with a trend towards a lower complication rate with increasing experience.Conclusions:The LB2 was safe and effective for PVI, even for operators without any previous experience in laser balloon-based PVI. Procedure time, left atrial dwelling time and fluoroscopy time decreased after a learning curve of 15 cases.

著者

Shuntaro Itagaki Tomohiro Wada Shunya Yokokura Yoko Ise Akiko Sato Takatomo Matsumoto Hirobumi Mashiko Shin-ichi Niwa Hirooki Yabe

出版者

THE FUKUSHIMA SOCIETY OF MEDICAL SCIENCE

雑誌

FUKUSHIMA JOURNAL OF MEDICAL SCIENCE (ISSN:00162590)

巻号頁・発行日

vol.65, no.2, pp.68-69, 2019 (Released:2019-08-30)

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This is based on a survey of two-year-old but not three-year-old cohorts. Therefore, we cannot state anything about the incidence of autism spectrum disorder (ASD) in over three-years-old children. We submit corrections in the following errata, because the original sentences might mislead the readers without evidence from three-year-old children. Also, we would like to exclude the phrase of “low-dose radiation” from the sections of Key word, Abstract, and Conclusion, because this study did not cover its influence.Author Shuntaro ItagakiAugust 05, 2019

著者

Koji Kanamori Noriko Ihana-Sugiyama Ritsuko Yamamoto-Honda Tomoka Nakamura Chie Sobe Shigemi Kamiya Miyako Kishimoto Hiroshi Kajio Kimiko Kawano Mitsuhiko Noda

出版者

Tohoku University Medical Press

雑誌

The Tohoku Journal of Experimental Medicine (ISSN:00408727)

巻号頁・発行日

vol.243, no.1, pp.35-39, 2017 (Released:2017-09-15)

参考文献数

13

被引用文献数

7

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Carbohydrate-restricted diets are prevalent not only in obese people but also in the general population to maintain appropriate body weight. Here, we report that extreme carbohydrate restriction for one day affects the subsequent blood glucose levels in healthy adults. Ten subjects (median age 30.5 years, BMI 21.1 kg/m2, and HbA1c 5.5%), wearing with a continuous glucose monitoring device, were given isoenergetic test meals for 4 consecutive days. On day 1, day 2 (D2), and day 4 (D4), they consumed normal-carbohydrate (63-66% carbohydrate) diet, while on day 3, they took low-carbohydrate/high-fat (5% carbohydrate) diet. The daily energy intake was 2,200 kcal for males and 1,700 kcal for females. On D2 and D4, we calculated the mean 24-hr blood glucose level (MEAN/24h) and its standard deviation (SD/24h), the area under the curve (AUC) for glucose over 140 mg/dL within 4 hours after each meal (AUC/4h/140), the mean amplitude of the glycemic excursions (MAGE), the incremental AUC of 24-hr blood glucose level above the mean plus one standard deviation (iAUC/MEAN+SD). Indexes for glucose fluctuation on D4 were significantly greater than those on D2 (SD/24h; p = 0.009, MAGE; p = 0.013, AUC/4h/140 after breakfast and dinner; p = 0.006 and 0.005, and iAUC/MEAN+SD; p = 0.007). The value of MEAN/24h and AUC/4h/140 after lunch on D4 were greater than those on D2, but those differences were not statistically significant. In conclusion, consumption of low-carbohydrate/high-fat diet appears to cause higher postprandial blood glucose on subsequent normal-carbohydrate diet particularly after breakfast and dinner in healthy adults.

著者

edited by Çiğdem Balım-Harding Colin Imber

出版者

Isis Press

巻号頁・発行日

2000

著者

Kentaro Kamiya Takanobu Yamamoto Miyuki Tsuchihashi-Makaya Toshimi Ikegame Tetsuya Takahashi Yukihito Sato Norihiko Kotooka Yoshihiko Saito Hiroyuki Tsutsui Hiroaki Miyata Mitsuaki Isobe

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

pp.CJ-19-0241, (Released:2019-06-11)

参考文献数

20

被引用文献数

70

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Background:The purpose of this study was to clarify the implementation rate of multidisciplinary heart failure (HF) care and cardiac rehabilitation (CR) in Japan, as well as the relationship between implementation rates and characteristics of the facility.Methods and Results:Survey participants were cardiologists who are members of the Japan Heart Failure Society and belonged to 1 of 845 medical institutions that are members of the Japan Heart Failure Society, as of April 2016. A total of 288 institutions (34.1%) returned the questionnaire. The percentages of hospitals implementing multidisciplinary HF care were 78.5% for inpatients and 32.6% for outpatients with HF. Inpatient and outpatient CR for HF had implementation rates of 80.4% and 56.5%, respectively. In addition, very few HF patients (7.3%, 3,741/51,323 patients) received outpatient CR. Both the presence of nurses certified in chronic HF care and registered CR instructors on staff were consistently associated with implementation of multidisciplinary HF care, and Japanese Circulation Society training hospitals, lower number of hospital beds, and presence of registered CR instructors on staff were consistently associated with implementation of CR.Conclusions:This first nationwide survey demonstrated that the implementation rates of multidisciplinary care and CR for HF, especially for outpatients, are low in Japan. Skilled healthcare professionals are expected to play important roles in the widespread implementation of this type of HF care in Japan.

著者

Eitaro Kodani Hiroshi Inoue Hirotsugu Atarashi Ken Okumura Takeshi Yamashita Hideki Origasa on behalf of the J-RHYTHM Registry Investigators

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

pp.CJ-19-0267, (Released:2019-06-19)

参考文献数

34

被引用文献数

5

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Background:Because the influence of digitalis use on the death of patients with non-valvular atrial fibrillation (NVAF) remains controversial, a subanalysis of the J-RHYTHM Registry was performed.Methods and Results:A consecutive series of outpatients with AF from 158 institutions was enrolled and followed for 2 years or until the occurrence of an event. Among 7,406 patients with NVAF, 7,018 (age, 69.7±10.0 years; men, 71.1%) with information on antiarrhythmic drug and digitalis use at baseline were divided into 2 groups based on digitalis use. The influence of digitalis on death was investigated using a propensity score-matching model. In 802 patients treated with digitalis, all-cause death was significantly higher than in 6,216 patients with no digitalis use during the 2-year follow-up period (4.4% vs. 2.4%, unadjusted P<0.001). Digitalis use was significantly associated with all-cause death in the crude model (hazard ratio [HR] 1.85, 95% confidence interval [CI] 1.28–2.68, P=0.001). However, after propensity score-matching, the association was not significant (HR 1.31, 95% CI 0.70–2.46, P=0.405). Older age, male sex, heart failure, coronary artery disease, and lower body mass index were significantly associated with all-cause death in NVAF patients treated with digitalis.Conclusions:Digitalis use was not independently associated with all-cause death, and several clinical confounding factors might contribute to increased mortality in NVAF patients treated with digitalis.

著者

Tomomi Kinoshita Shu-ichi Ikeda

出版者

The Japanese Society of Internal Medicine

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

vol.54, no.15, pp.1955, 2015 (Released:2015-08-01)

参考文献数

6

被引用文献数

2 2

著者

林 宏作 Hong-Zuo Lin 桃山学院大学文学部

雑誌

国際文化論集 = INTERCULTURAL STUDIES (ISSN:09170219)

巻号頁・発行日

no.11, pp.(7)-(17), 1995-01-30

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本論文は、『三国志』・『晉書』の正史をはじめ、阮籍自らの著作や『世説新語』及びその注に引用された諸々の資料に基づき、いままで史書に明示されていない阮籍の歴任した官職の年月を考証するものである。この考証によって、阮籍の生涯が一層はっきりするとともに、唐代に編集された『晉書』の誤った記載も明らかにした。しかし一七〇〇余年も昔のこと故、すべてを解明できたとは言い難いが、現時点では最も精確な結論に達したと思う。いまここで本論文の考証によって得られた結論だけを次に記しておこう。阮籍が「吏」として蒋済に招かれたのは二四二年、三三歳のときである。これは阮籍の最初の仕官である。その後、三九歳(二四八年)のときに「尚書郎」となり、そして同じ年に曹爽の「参軍」として招かれたのである。曹爽が失脚した後、阮籍は司馬懿によって「従事中郎」を命じられている。この任期は恐らく正始十年(二四九)三月から司馬懿の死した嘉平三年(二五一)八月までであろう。司馬懿の死後、阮籍は続いて司馬師の「従事中郎」に任じられ、正元元年(二五四)十月「散騎常侍」に移るまで、その任にあったと考えられる。そして自ら「東平の相」を求め、三たび「従事中郎」となり、「歩兵校尉」となったのはすべて司馬昭の執政の時代であり、二五五年二月から二五八年五月まで、つまり阮籍の四六歳から四九歳の間のことである、と史料によって推測するものである。In this paper I investigate into the historical evidences of Ruan Ji's successive posts in the government which hitherto have remained unspecified in the history books. The materials on which my research based were Sanguozhi, Jinshu, Ruan Ji's own writings, Shishuoxinyu and various notes quoted in the book. Notwithstanding the fact that I could not solve all the problems concerning the career of Ruan Ji, yet I believe at the present I have attained the most exact conclusion about the matter. The career of Ruan Ji was made clearer than before and incorrect records in Jinshu compiled during Tang period were disclosed. Here, I would like to epitomize only the conclusions attained by the investigation. It was when he was 33 years old in 242 A. D., that Ruan Ji was engaged by Jiang Ji as a government official. This was his first entrance into the government service. Later, when he was at the age of 39 in 248 A. D., he became Shangshulang and in the same year he was engaged by Cao Shuang as Canjun. After Cao Shuang lost his position, Ruan Ji was appointed to Congshizhonglang by Sima Yi. The term of this office was, perhaps, from March, 249 A. D., the tenth year of the Zhengshi era, to August, 251 A. D., the third year of the Jiapeng era, when Si-ma Yi died. After the death of Si-ma Yi, Ruan Ji was successively appointed to Congshizhonglang by Si-ma Shi, and he seemed to have remained in the office untill he was transferred to Sanjichangshi in October, 254 A. D., the first year of the Zhengyuan era. Then, he requested himself and took the office of "Minister of Dongpeng district", and thereafter for the third time he was appointed to Congshizhonglang and further to Bubingjiaowei. All these, I surmise, were during the period of Si-ma Zhao's administration, i. e., from February, 255 A. D. to May, 258 A. D., when Ruan Ji was at the age between 46 and 49.

著者

Kikuo TAKAO Ken-ichi URUGA

出版者

Railway Technical Research Institute

雑誌

Quarterly Report of RTRI (ISSN:00339008)

巻号頁・発行日

vol.44, no.3, pp.103-108, 2003 (Released:2006-07-20)

被引用文献数

1 3

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We have been developing a variable gauge system for through-operation between standard-gauge Shinkansen and narrow-gauge conventional sections since 1994. A Gauge Change Train (GCT), an experimental 3-motor-car electric multiple unit (EMU), was completed for test purposes in autumn 1998 to verify the basic efficiency of this system. It has been designed to run at a maximum speed of over 300 km/h on Shinkansen and 130 km/h on conventional lines under a catenary voltage of 20 kV, 25 kV (50/60 Hz) AC and 1.5 kV DC. It had already been for a year's high-speed endurance evaluation at the Transportation Technology Center in Pueblo, U.S.A. from spring 1999 before being subjected to highspeed and curving performance trials on JR Kyushu and JR Shikoku narrow-gauge lines and gauge change performance and AC-DC section running tests with JR West from 2001 to 2003. We verified running stability at 130km/h on narrow gauge lines and will implement a high-speed performance test on Shinkansen lines in the near future.

著者

徐 竜達 Yong-Dal Suh

出版者

桃山学院大学経済学会

雑誌

桃山学院大学経済学論集 (ISSN:0286990X)

巻号頁・発行日

vol.14, no.3, pp.158-194, 1972-12

著者

Nozomi SAITO Jaymee R. ENCABO Sunlu CHEN Gilda JONSON Yuji KISHIMA Il-Ryong CHOI

出版者

Japan International Research Center for Agricultural Sciences

雑誌

Japan Agricultural Research Quarterly: JARQ (ISSN:00213551)

巻号頁・発行日

vol.53, no.1, pp.1-6, 2019-01-01 (Released:2019-01-30)

参考文献数

25

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Rice tungro disease (RTD) is a serious threat to rice production in South and Southeast Asia. RTD is caused by Rice tungro bacilliform virus (RTBV) and Rice tungro spherical virus (RTSV). Coinfection of RTSV and RTBV results in more severe symptoms in African rice Oryza glaberrima than in Asian rice O. sativa. In this study, we examined whether RTBV alone causes more severe symptoms in O. glaberrima than in O. sativa. The examination of 18 accessions of O. glaberrima for RTBV infection indicated that all the O. glaberrima accessions examined were susceptible to RTBV. The reactions to RTBV of three O. glaberrima accessions and two RTBV-susceptible varieties of O. sativa, Taichung Native 1 (TN1) and IR 64, were compared. RTBV accumulation varied depending on the plants and differences in RTBV accumulation were not evident between the two species. However, the O. glaberrima accessions were significantly more stunted by RTBV than IR 64 was. Discoloration of leaves by RTBV was evident in the O. glaberrima plants, but not in the O. sativa plants. Collectively, these results presumably indicated that O. glaberrima is generally more vulnerable to RTBV than O. sativa is.

著者

金 承台[著] 蔵田 雅彦(訳) Sung-tae Kim Masahiko Kurata 桃山学院大学文学部

出版者

桃山学院大学総合研究所

雑誌

桃山学院大学キリスト教論集 = St. Andrew's University Journal of Christian Studies (ISSN:0286973X)

巻号頁・発行日

no.29, pp.87-107, 1993-03-31

著者

Yo-Han Uhm Dae-Jung Yang

出版者

The Society of Physical Therapy Science

雑誌

Journal of Physical Therapy Science (ISSN:09155287)

巻号頁・発行日

vol.30, no.2, pp.300-303, 2018 (Released:2018-02-28)

参考文献数

11

被引用文献数

2

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[Purpose] The purpose of this study was to examine the effect of computerized postural control training using whole body vibration on lower limb muscle activity and cerebral cortical activation in acute stroke patients. [Subjects and Methods] Thirty stroke patients participated and were divided into groups of 10, a group of the computerized postural control training using whole body vibration (Group I), the computerized postural control training combined with aero step (Group II) and computerized postural control training (Group III). MP100 was used to measure lower limb muscle activity, and QEEG-8 was used to measure cerebral cortical activation. [Results] Comparison of muscle activity and cerebral cortical activation before and after intervention between groups showed that Group I had significant differences in lower limb muscle activity and cerebral cortical activation compared to Groups II and III. [Conclusion] This study showed that whole body vibration combined computerized postural control training is effective for improving muscle activity and cerebral cortex activity in stroke patients.

著者

Yamasaki Chisato Murakami Katsuhiko Fujii Yasuyuki Sato Yoshiharu Harada Erimi Takeda Jun-ichi Taniya Takayuki Satake Ryuichi Kikugawa Shingo Shimada Makoto Tanino Motohiko Halligan Brian Shimoyama Mary Twigger Simon Yura Kei Kimura Kouichi Yasuda Tomohiro Nishikawa Tetsuo Akiyama Yutaka Motono Chie Mukai Yuri Shionyu Masafumi Nagasaki Hideki Suwa Makiko Horton Paul Kikuno Reiko Ohara Osamu Lancet Doron Eveno Eric Graudens Esther Imbeaud Sandrine Debily Marie Anne Jia Libin Hayashizaki Yoshihide Amid Clara Han Michael Osanger Andreas Endo Toshinori Thomas Michael A. Hirakawa Mika Makalowski Wojciech Nakao Mitsuteru Kim Nam-Soon Thierry-Mieg Danielle Yoo Hyang-Sook De Souza Sandro J. Bonaldo Maria de Fatima Niimura Yoshihito Kuryshev Vladimir Schupp Ingo Wiemann Stefan Bellgard Matthew Thierry-Mieg Jean Wagner Lukas Zhang Qinghua Go Mitiko Minoshima Shinsei Ohtsubo Masafumi Hanada Kousuke Koyanagi Kanako O. Tonellato Peter Isogai Takao Zhang Ji Lenhard Boris Kim Sangsoo Chen Zhu Hinz Ursula Estreicher Anne Nakai Kenta Makalowska Izabela Barrero Roberto A. Hide Winston Tiffin Nicola Wilming Laurens Chakraborty Ranajit Soares Marcelo Bento Chiusano Maria Luisa Suzuki Yutaka Auffray Charles Yamaguchi-Kabata Yumi Itoh Takeshi Gough Craig Hishiki Teruyoshi Fukuchi Satoshi Nishikawa Ken Sugano Sumio Nomura Nobuo Tateno Yoshio Imanishi Tadashi Gojobori Takashi Chun Hong-Woo Habara Takuya Hanaoka Hideki Hayakawa Yosuke Hilton Philip B. Kaneko Yayoi Kanno Masako Kawahara Yoshihiro Kawamura Toshiyuki Matsuya Akihiro Nagata Naoki Nishikata Kensaku Ogura Noda Akiko Nurimoto Shin Saichi Naomi Sakai Hiroaki Sanbonmatsu Ryoko Shiba Rie Suzuki Mami Takabayashi Kazuhiko Takahashi Aiko Tamura Takuro Tanaka Masayuki Tanaka Susumu Todokoro Fusano Yamaguchi Kaori Yamamoto Naoyuki Okido Toshihisa Mashima Jun Hashizume Aki Jin Lihua Lee Kyung-Bum Lin Yi-Chueh Nozaki Asami Sakai Katsunaga Tada Masahito Miyazaki Satoru Makino Takashi Ohyanagi Hajime Osato Naoki Tanaka Nobuhiko Suzuki Yoshiyuki Ikeo Kazuho Saitou Naruya Sugawara Hideaki O'Donovan Claire Kulikova Tamara Whitfield Eleanor

出版者

Oxford University Press

雑誌

Nucleic Acids Research (ISSN:03051048)

巻号頁・発行日

vol.36, no.1, pp.D793-D799, 2008-01

被引用文献数

12

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Here we report the new features and improvements in our latest release of the H-Invitational Database (H-InvDB; http://www.h-invitational.jp/), a comprehensive annotation resource for human genes and transcripts. H-InvDB, originally developed as an integrated database of the human transcriptome based on extensive annotation of large sets of full-length cDNA (FLcDNA) clones, now provides annotation for 120 558 human mRNAs extracted from the International Nucleotide Sequence Databases (INSD), in addition to 54 978 human FLcDNAs, in the latest release H-InvDB_4.6. We mapped those human transcripts onto the human genome sequences (NCBI build 36.1) and determined 34 699 human gene clusters, which could define 34 057 (98.1%) protein-coding and 642 (1.9%) non-protein-coding loci; 858 (2.5%) transcribed loci overlapped with predicted pseudogenes. For all these transcripts and genes, we provide comprehensive annotation including gene structures, gene functions, alternative splicing variants, functional non-protein-coding RNAs, functional domains, predicted sub cellular localizations, metabolic pathways, predictions of protein 3D structure, mapping of SNPs and microsatellite repeat motifs, co-localization with orphan diseases, gene expression profiles, orthologous genes, protein–protein interactions (PPI) and annotation for gene families. The current H-InvDB annotation resources consist of two main views: Transcript view and Locus view and eight sub-databases: the DiseaseInfo Viewer, H-ANGEL, the Clustering Viewer, G-integra, the TOPO Viewer, Evola, the PPI view and the Gene family/group.

著者

Mariko Harada-Shiba Hidenori Arai Yasushi Ishigaki Shun Ishibashi Tomonori Okamura Masatsune Ogura Kazushige Dobashi Atsushi Nohara Hideaki Bujo Katsumi Miyauchi Shizuya Yamashita Koutaro Yokote Working Group by Japan Atherosclerosis Society for Making Guidance of Familial Hypercholesterolemia

出版者

Japan Atherosclerosis Society

雑誌

Journal of Atherosclerosis and Thrombosis (ISSN:13403478)

巻号頁・発行日

pp.CR003, (Released:2018-06-07)

参考文献数

74

被引用文献数

167

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Statement1. Familial hypercholesterolemia (FH) is an autosomal hereditary disease with the 3 major clinical features of hyper-LDL-cholesterolemia, premature coronary artery disease and tendon and skin xanthomas. As there is a considerably high risk of coronary artery disease, in addition to early diagnosis and intensive treatment, family screening (cascade screening) is required (Recommendation level A)2.For a diagnosis of FH, at least 2 of the following criteria should be satisfied:① LDL-C ≥180 mg/dL, ② Tendon/skin xanthomas, ③ History of FH or premature coronary artery disease (CAD) within 2nd degree blood relatives (Recommendation level A)3. Intensive lipid-lowering therapy is necessary for the treatment of FH. First-line drug should be statin. (Recommendation level A, evidence level 3)4.Screening for coronary artery disease as well as asymptomatic atherosclerosis should be conducted periodically in FH patients. (Recommendation level A)5. For homozygous FH, consider LDL apheresis and treatment with PCSK9 inhibitors or MTP inhibitors. (Recommendation level A)6.For severe forms of heterozygous FH who have resistant to drug therapy, consider PCSK9 inhibitors and LDL apheresis. (Recommendation level A)7.Refer FH homozygotes as well as heterozygotes who are resistant to drug therapy, who are children or are pregnant or have the desire to bear children to a specialist. (Recommendation level A)

著者

Sang-Hyun Moon Jung-Hyun Choi Si-Eun Park

出版者

The Society of Physical Therapy Science

雑誌

Journal of Physical Therapy Science (ISSN:09155287)

巻号頁・発行日

vol.29, no.2, pp.238-241, 2017 (Released:2017-02-24)

参考文献数

25

被引用文献数

1 17

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[Purpose] The purpose of this study was to determine the effects of functional electrical stimulation on muscle tone and stiffness in stroke patients. [Subjects and Methods] Ten patients who had suffered from stroke were recruited. The intervention was functional electrical stimulation on ankle dorsiflexor muscle (tibialis anterior). The duration of functional electrical stimulation was 30 minutes, 5 times a week for 6 weeks. The Myoton was used a measure the muscle tone and stiffness of the gastrocnemius muscle (medial and lateral part) on paretic side. [Results] In the assessment of muscle tone, medial and lateral part of gastrocnemius muscle showed differences before and after the experiment. Muscle stiffness of medial gastrocnemius muscle showed differences, and lateral gastrocnemius muscle showed differences before and after the experiment. The changes were greater in stiffness scores than muscle tone. [Conclusion] These results suggest that FES on ankle dorsiflexor muscle had a positive effect on muscle tone and stiffness of stroke patients.

著者

Khusraw Nasir-i 長峯 博之 北海道大学ペルシア語史料研究会

出版者

北海道大学文学部東洋史談話会

雑誌

史朋 (ISSN:03865142)

巻号頁・発行日

no.35, pp.1-29, 2003-02

著者

Sung-Tae Kim Joon-Hee Lee

出版者

The Society of Physical Therapy Science

雑誌

Journal of Physical Therapy Science (ISSN:09155287)

巻号頁・発行日

vol.29, no.2, pp.194-197, 2017 (Released:2017-02-24)

参考文献数

30

被引用文献数

8

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[Purpose] To investigate the effects of Pilates breathing on trunk muscle activation. [Subjects and Methods] Twenty-eight healthy female adults were selected for this study. Participants’ trunk muscle activations were measured while they performed curl-ups, chest-head lifts, and lifting tasks. Pilates breathing trainings were performed for 60 minutes per each session, 3 times per week for 2 weeks. Post-training muscle activations were measured by the same methods used for the pre-training muscle activations. [Results] All trunk muscles measured in this study had increased activities after Pilates breathing trainings. All activities of the transversus abdominis/internal abdominal oblique, and multifidus significantly increased. [Conclusion] Pilates breathing increased activities of the trunk stabilizer muscles. Activation of the trunk muscle indicates that practicing Pilates breathing while performing lifting tasks will reduce the risk of trunk injuries.

著者

Jeong-il Kang Dae-Keun Jeong Hyun Choi

出版者

The Society of Physical Therapy Science

雑誌

Journal of Physical Therapy Science (ISSN:09155287)

巻号頁・発行日

vol.30, no.1, pp.37-41, 2018 (Released:2018-01-27)

参考文献数

28

被引用文献数

7

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[Purpose] The purpose of the present study was to apply early intervention via microcurrent and cryotherapy in patients who underwent rotator cuff reconstruction surgery, and to investigate the effects of such interventions on pain and inflammation levels based on the analysis of C-reactive protein (CRP) levels, and on changes in muscle tone. [Subjects and Methods] The study population consisted of 30 patients who had undergone rotator cuff reconstruction surgery, with 10 patients each assigned to the control, experimental I (E-1), and experimental II (E-II) groups. On the day after surgery, muscle tone, blood CRP level, and pain were measured. For the following two weeks, continues passive motion (CPM), icing, cryotherapy, and microcurrent were applied to the each group. After the respective interventions, CRP levels, pain, and muscle tone near the shoulder area were measured again. [Results] In the post-hoc test of between-group comparison, a statistically significant difference in CRP level was found in the cryotherapy group. A difference in shoulder muscle tone appeared only in the supraspinatus muscle, with post-hoc test results showing that the biggest change occurred in the cryotherapy group. [Conclusion] Cryotherapy may be able to help stabilize inflammation as well as reduce pain and muscle tension when applied in patients following rotator cuff reconstruction.

著者

Hiroyuki Tsutsui Hiroshi Ito Masafumi Kitakaze Issei Komuro Toyoaki Murohara Tohru Izumi Kenji Sunagawa Yoshio Yasumura Masafumi Yano Kazuhiro Yamamoto Tsutomu Yoshikawa Takayoshi Tsutamoto Junwei Zhang Akifumi Okayama Yoshihiko Ichikawa Kazuhiro Kanmuri Masunori Matsuzaki for the J-EMPHASIS-HF Study Group

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

vol.82, no.1, pp.148-158, 2017-12-25 (Released:2017-12-25)

参考文献数

19

被引用文献数

23

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Background:The mineralocorticoid receptor antagonist eplerenone improved clinical outcomes among patients with heart failure with reduced ejection faction (HFrEF) in the EMPHASIS-HF (Eplerenone in Mild Patients Hospitalization And SurvIval Study in Heart Failure) study. However, similar efficacy and safety have not been established in Japanese patients. We evaluated the efficacy and safety of eplerenone in patients with HFrEF in a multicenter, randomized, double-blind placebo-controlled outcome study (ClinicalTrials.gov Identifier: NCT01115855). The aim of the study was to evaluate efficacy predefined as consistency of the primary endpoint with that of EMPHASIS-HF at a point estimate of <1 for the hazard ratio.Methods and Results:HFrEF patients with NYHA functional class II–IV and an EF ≤35% received eplerenone (n=111) or placebo (n=110) on top of standard therapy for at least 12 months. The primary endpoint was a composite of death from cardiovascular causes or hospitalization for HF. The primary endpoint occurred in 29.7% of patients in the eplerenone group vs. 32.7% in the placebo group [hazard ratio=0.85 (95% CI: 0.53–1.36)]. Hospitalization for any cause and changes in plasma BNP and LVEF were favorable with eplerenone. A total of 17 patients (15.3%) in the eplerenone group and 10 patients (9.1%) in the placebo group died. Adverse events, including hyperkalemia, were similar between the groups.Conclusions:Eplerenone was well-tolerated in Japanese patients with HFrEF and showed results consistent with those reported in the EMPHASIS-HF study.