著者

Kengo UEDA Akiko UEDA Kiyokazu OZAKI

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.81, no.2, pp.193-196, 2019 (Released:2019-02-09)

参考文献数

17

被引用文献数

4

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A tumor had formed in the right eye of a 14-year-old male chinchilla. The black-and-white-colored tumor occupied the entire eye except for the lens and had invaded extensively inside the orbit. Histologically, round, spindle- to polygonal-shaped tumor cells had proliferated in a solid-sheet arrangement. The tumor cells exhibited polymorphic nuclei ranging from round- to polygonal-shaped, as well as abundant cytoplasm, which occasionally contained melanin granules. In some areas, several cells were surrounded by the basal lamina. Additionally, the tumor showed cervical lymph-node metastasis. Upon immunostaining, the tumor cells were positive for epithelial markers (cytokeratin AE1/AE3, 8/18, and 20), S100, and vimentin. Consequently, we diagnosed primary pleomorphic iridociliary adenocarcinoma with lymph-node metastasis. This is the first report of iridociliary adenocarcinoma in chinchillas.

著者

Da-Eun LEE Kyu-Chang KIM Soon-Wuk JEONG Hun-Young YOON

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.81, no.2, pp.237-240, 2019 (Released:2019-02-19)

参考文献数

18

被引用文献数

6

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A castrated male Shih-Tzu dog was presented for evaluation of urine leakage after urethrotomy. A fistula with urine leakage was identified in the perineal region. On retrograde urethrography, the contrast extravasated from the penile urethra into the subcutaneous tissue of the perineum. Urine leakage with urethrocutaneous fistula was diagnosed. During surgery, the disrupted urethra wall and two urethral defects were identified. A fascia lata autograft was used, rather than primary repair of the urethra. Two pieces of fascia lata were harvested and sutured to the urethral defects. The fistula was treated with debridement and drainage. No evidence of urine leakage and dysuria was noted 6 months postoperatively. Thus, this case report describes successful urethral reconstruction using a fascia lata autograft.

著者

Du-Min GO Sang-Ho WOO Su-Hyung LEE Dae-Yong KIM

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.81, no.2, pp.177-181, 2019 (Released:2019-02-09)

参考文献数

19

被引用文献数

3

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A 3.9-year-old female African pygmy hedgehog (Atelerix albiventris) had a firm, tan-colored mass with an uneven surface arising from the mandibular salivary gland. A histopathologic examination revealed that the mass was composed of neoplastic proliferation of epithelial and spindle cells. The neoplastic spindle cells showed positive for vimentin, smooth muscle actin, calponin and cytokeratin 14 and, negative for cytokeratin 19, suggesting that spindle cells were derived from myoepithelial cells. Based on the histological findings and immunohistochemistry results, the mass was diagnosed as pleomorphic adenoma. Pleomorphic adenoma is the most common benign tumor found in human salivary glands, but it is rare in animals. To the best of our knowledge, this is the first report of pleomorphic adenoma in hedgehogs.

著者

Tomoaki MURAKAMI Tomoyuki MIYOSHI Natsumi TAKAHASHI Akihisa KANGAWA

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.81, no.3, pp.357-360, 2019 (Released:2019-03-14)

参考文献数

11

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Two Large Yorkshire piglets were diagnosed as persistent hyperplastic primary vitreous (PHPV). In case 1, the white cord-like structure extending from optic disc to lens was observed in the normal-sized right eye. Case 2 showed buphthalmos of the right eye. The internal structure of the right eye was unclear due to bleeding, but a white cord-like structure was slightly observed. In both cases, histological examinations revealed the fibrovascular cord-like structure in hyaloid vitreous. The retina was detached, and dysplastic nervous tissue was observed in anterior vitreous. Immunohistochemistry using various neural markers suggested that dysplastic nervous tissue was derived from the detached neural retina. By the characteristic macroscopic and histopathological features, both cases were diagnosed as PHPV. To our knowledge, this is the first report of swine PHPV.

著者

Keisuke SAITO Mohie HARIDY Walied ABDO Ahmed EL-MORSEY Samy KASEM Yukiko WATANABE Tokuma YANAI

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.81, no.2, pp.338-342, 2019 (Released:2019-02-28)

参考文献数

23

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A severely emaciated adult Steller’s sea eagle (Haliaeetus pelagicus) was found dead with electrocution-induced severe wing laceration, and with multiple cutaneous pock nodules at the periocular regions of both sides nearby the medial canthi and rhamphotheca. Histopathological examination of the nodules revealed hyperplasia of the epidermis with vacuolar degeneration and intracytoplasmic inclusion bodies (Bollinger bodies). The proventriculus was severely affected by nematodes and was ulcerated. Nucleotide sequencing of a PCR-amplified product of Avipoxvirus 4b core gene revealed 100% identity to the sequence of Avipoxvirus derived from other eagle species. This report describes the first detection of Avipoxvirus clade A from a Steller’s sea eagle.

著者

Adam STERN

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.81, no.2, pp.190-192, 2019 (Released:2019-02-09)

参考文献数

8

被引用文献数

2

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Cases of hyperthermia caused by exposure to high environmental temperature are not uncommonly encountered in dogs. The circumstances surrounding the exposure to high environmental temperature may be accidental or intentional; thus highlighting the importance to perform a forensic autopsy. This report documents three cases of canine environmentally induced hyperthermia and all dogs in this report died less than 6 hr after exposure to the high environmental temperatures. The most commonly observed macroscopic findings included cutaneous petechial and ecchymotic hemorrhage, pulmonary edema and congestion, and epicardial and endocardial hemorrhage. Microscopically, there was systemic vascular congestion and hemorrhage, fibrin thrombi formation, and occasional enterocyte and/or renal tubular necrosis. The findings from all cases were consistent with hyperthermia induced disseminated intravascular coagulation.

著者

Naris THENGCHAISRI Chulabhorn MAHIDOL

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.18-0448, (Released:2019-03-15)

被引用文献数

7

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The sparing effects of tramadol and tramadol-lidocaine infusion on the minimum alveolar concentration (MAC) of sevoflurane in dogs as well as the entropy indices were investigated. Anesthesia was induced in eight young, healthy German shepherds weighing 27.6 ± 3.2 kg (mean ± SD) and maintained with sevoflurane. A standard tail-clamp technique was used to determine sevoflurane MAC during infusion with: sevoflurane alone to measure baseline MAC (MACB); tramadol (intravenous loading dose of 1.5 mg/kg and constant rate infusion [CRI] of 2.6 mg/kg/hr; MACT); and tramadol-lidocaine (tramadol CRI of 2.6 mg/kg/hr; and lidocaine intravenous loading dose of 1.0 mg/kg and CRI of 6 mg/kg/hr; MACTL). The state entropy (SE), response entropy (RE), and RE-SE difference were recorded 5 min prior to and during tail clamping. MACB was 2.4 ± 0.2%. Tramadol and tramadol-lidocaine CRI decreased MAC to 2.2 ± 0.3% and 1.7 ± 0.3%, respectively. The MAC-sparing effect of tramadol-lidocaine was greater than that of tramadol alone (8.2 ± 8.9% vs. 30.1 ± 10.7%; P<0.01). SE and RE in all subjects, and RE-SE difference in most subjects, were increased (all P<0.05) when they responded purposefully to noxious stimulation. A tramadol-lidocaine combination infusion can reduce anesthetic requirements to a higher degree than tramadol alone. Furthermore, MACentropy, MAC required to prevent increased entropy in response to a painful stimulation, and MAC of sevoflurane were similar in dogs.

著者

Kazuki OKADA Yumiko KAGAWA

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.19-0037, (Released:2019-03-12)

被引用文献数

2

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A 9-year-old castrated male cat presented with sudden onset of paralysis in four limbs. Magnetic resonance imaging revealed an intramedullary lesion at C3, and lesions in the vermis and right hemisphere of the cerebellum, which were hyperintense on T2-weighted imaging. The cat was euthanized, and postmortem examination was performed. Grossly, transverse sectioning of the spinal cord revealed areas of malacia within the gray matter extending from C2 to C3. Histologically, the ventral spinal artery, the spinal intramedullary arteries and the arterioles of arachnoid in the cerebellum contained fibrocartilaginous emboli confirmed by metachromatic staining with toluidine blue. To our knowledge, this is the first report of fibrocartilaginous embolism involving both the cerebellum and cervical spinal cord in a cat.

著者

Cristina CARNABUCI Rosalba TOGNETTI Tommaso VEZZOSI Federica MARCHESOTTI Valentina PATATA Oriol DOMENECH

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.18-0699, (Released:2019-03-11)

被引用文献数

6

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In canine electrocardiography, the reference interval of the ventricular mean electrical axis (MEA) is between +40° and +100°. MEA values in dogs can be influenced by the patient position as well as by the shape of the thorax. The aim of this study was to evaluate the MEA in healthy Doberman Pinschers, hypothesizing that some present a left shift of the MEA. In this retrospective study, 41 healthy, client-owned Doberman Pinschers were included. Echocardiography and standard six-lead ECG examination were performed in all dogs. The MEA was calculated using the isoelectric method. The morphology of the QRS complex and the Q/R ratio in lead II were also evaluated. The median MEA was +45° and ranged from –45° to +90°. MEA was deviated in 16/41 dogs (39%), all presenting a left axis deviation (range, –45° to +30°). Age was significantly associated with the MEA (P=0.008), showing a negative linear correlation. A deep Q wave in lead II was present in 26/41 (63%) dogs. The Q/R ratio was higher in dogs presenting left shift of the MEA (0.66; range, 0.28–1.35) in comparison to dogs with a MEA within reference range (0.44; range, 0.04–0.73; P<0.001). In conclusion, a significant number of healthy Doberman Pinschers present a left shift of the MEA compare to the reference range, and dogs with MEA deviation show a higher Q/R ratio in lead II. This data should be considered when electrocardiographic evaluation is performed in Doberman Pinschers.

著者

佐々木 栄英 北川 均 藤岡 透 鬼頭 克也 岩崎 利郎 坂口 雅弘 井上 栄

出版者

社団法人日本獣医学会

雑誌

The journal of veterinary medical science (ISSN:09167250)

巻号頁・発行日

vol.57, no.4, pp.683-685, 1995-08-15

参考文献数

15

被引用文献数

8

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慢性皮膚疾患に感染した51頭の犬に対して, 34種の抗原を用いて, 皮内反応テストを実施した結果, 4例がスギ花粉抗原に陽性反応を示した. この4例は, Prausnitz-Kustnerテストが陽性で, スギ花粉に対する特異IgE抗体を持っていることが示された. さらに, スギ花粉の素抗原を鼻腔内に滴下し, 臨床観察を行ったところ3例中2例で鼻汁の漏出を認めた. 以上の結果から, これらの大はスギ花粉に対する過敏性と診断され, スギ花粉は犬のアトピー性疾患の原因の一つであることが明らかにされた.

著者

増田 宏司 橋爪 千恵 菊水 健史 武内 ゆかり 森 裕司

出版者

社団法人日本獣医学会

雑誌

The journal of veterinary medical science (ISSN:09167250)

巻号頁・発行日

vol.66, no.2, pp.183-187, 2004-02-25

参考文献数

19

被引用文献数

7

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人においてカテコールO-メチル基転移酵素(COMT)遺伝子の第4エクソンに存在する一塩基多型(G322A)はバリンからメチオニンヘのアミノ酸置換を伴い,酵素の活性を変化させるとともに"固執"や"統合失調症"といった性格や精神疾患との関連が示唆されている.そこで,犬における同様な多型を検索する目的で,まず犬のCOMT遺伝子断片のPCR増幅を試みた.得られた663 bp の遺伝子は人やラット,マウスのCOMT遺伝子と82%以上の相同性を有しており,犬COMT遺伝子である可能性が示された.続いて10頭のビーグル犬より得られたcDNAをもとに同遺伝子の多型部位を検索したところ,翻訳領域39,216,482番目に一塩基多型(G39A, G216A, G482A)が認められ,そのうちG482Aはアルギニンからグルタミンヘのアミノ酸置換を伴うものであった.さらに5犬種(ゴールデンレトリバー,ラブラドールレトリバー,マルチーズ,ミニチュアシュナウザー,シバ)から成る計266頭の血液より得られたゲノムDNAを用いてこれらの一塩基多型の発現頻度を犬種別に比較したところ,遺伝子型およびアレル頻度ともにG216AおよびG482Aについて有意な犬種差が認められた.これらの結果より,得られた遺伝子多型が犬の性格特性の遺伝的背景を探る上で有用な手掛かりとなる可能性が示された.

著者

Souta SUGIYAMA Yasuhiro UNO Tomoko AMANO Takio KITAZAWA Hiroki TERAOKA

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.18-0692, (Released:2019-03-04)

被引用文献数

4

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Knowledge on genetic polymorphisms of metabolising enzymes including Cytochrome P450 (CYP) is very limited in cats. We investigated polymorphisms in CYP3A131, one of the major CYP isoforms in the feline liver and small intestine. Eight non-synonymous variants and one synonymous variant of feline CYP3A131 were identified in 29 cats. A major non-synonymous type was not observed. Metabolic parameters (Km and Vmax) of dibenzylfluorescein hydroxylation were ranged within about 2 times for the identified non-synonymous variants by using a heterologous coexpression system of CYP3A131 and feline cytochrome P450 reductase in Escherichia coli. The results confirmed the polymorphic nature of CYP3A131 as a basis for effective application of medicines and prevention of adverse reactions in the treatment of domestic cats.

著者

Akira SHIOZAKI Masao AMANO Mercedes FERNÁNDEZ Natalia FRAIJA-FERNÁNDEZ

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.18-0636, (Released:2019-02-25)

被引用文献数

2

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Synthesium elongatum (Brachycladiidae) is an intestinal digenean described from the finless porpoise (Neophocaena asiaeorientalis) in Japan. Few records of this species exist and there is a remarkable morphological similarity between S. elongatum and S. tursionis, such that a synonymy between the species has been suggested previously. However, no morphological and/or molecular analysis has been carried out to clarify the taxonomic status of S. elongatum. In this study, we collected specimens of Synthesium sp. from N. asiaeorientalis in western Japan. The specimens possess lobed testes within the third quarter of the body, a round ovary, and vitellaria extending to level of uterine field, which are diagnostic characters for both S. elongatum and S. tursionis. They were morphologically identified to S. elongatum or S. tursionis due to the fact that the available morphometric data for both species overlap remarkably. A molecular analysis of the mitochondrial ND3 gene showed that the pairwise nucleotide distances between these specimens and S. tursionis were small, and phylogenetic analysis showed that these specimens and S. tursionis are in the same clade. Therefore, it was indicated that S. elongatum and S. tursionis are the same species and, consequently, S. elongatum is a synonym of S. tursionis.

著者

Kazuaki SATO Kazutaka KANAI Maiko OZAKI Takaaki KAGAWA Mizuki KITA Yohei YAMASHITA Noriaki NAGAI Kazuki TAJIMA

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.18-0723, (Released:2019-02-25)

被引用文献数

3

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We investigated the effects of tyrosol (Tyr) on anterior chamber paracentesis (ACP)–induced anterior uveitis in beagle dogs, as determined by protein and prostaglandin E2 (PGE2) concentrations in the aqueous humor (AH). Tyr at a dose of 100 or 200 mg/kg or 2.2 mg/kg of carprofen as a positive control was administered orally twice daily from 2.5 days before paracentesis. The initial ACP was performed in one eye of individual dogs and 0.5 ml AH was aspirated. The secondary AH was collected 60 min later. Pretreatment with 200 mg/kg of Tyr and carprofen significantly decreased aqueous protein and PGE2 concentrations compared to the control group. Overall, these findings suggested that Tyr was useful for the management of canine anterior uveitis.

著者

藤村 正人 大森 啓太郎 増田 健一 辻本 元 阪口 雅弘

出版者

社団法人日本獣医学会

雑誌

The journal of veterinary medical science (ISSN:09167250)

巻号頁・発行日

vol.64, no.11, pp.1069-1070, 2002-10

参考文献数

11

被引用文献数

1 21

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スギ(Cryptomeria japonica)花粉症の犬が新鮮なトマトを摂取した後,口腔アレルギー症候群(OAS)を発症した.この犬は血清特異的IgE検査でスギ花粉とトマト抗原の両方に陽性を示した.また,スギ花粉とトマト抗原の間でIgE交差反応が認められた.本研究においてトマトのOASが犬に存在して,スギ花粉とトマト抗原との間に関係があることが分かった.

著者

中臺 文 黒木 俊郎 加藤 行男 鈴木 理恵子 山井 志朗 柳沼 千春 塩谷 亮 山内 昭 林谷 秀樹

出版者

社団法人日本獣医学会

雑誌

The journal of veterinary medical science (ISSN:09167250)

巻号頁・発行日

vol.67, no.1, pp.97-101, 2005-01-25

参考文献数

21

被引用文献数

2 54

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2000年11月から2002年7月の間に,ペットショップの爬虫類112頭におけるサルモネラの保有状況を調査したところ,74.1%(83/112)と高率に本菌が分離された.分離された112株は5生物群に型別され,I群の割合(62.5%)が最も高かった.また,112株中54株は28血清型に型別可能であった.これらの成績から,ペットの爬虫類は人のサルモネラ症の感染源となる可能性が示唆された.

著者

秋庭 正人 佐伯 英治 石井 俊雄 山本 茂貴 上田 雄幹

出版者

社団法人日本獣医学会

雑誌

日本獣医学雑誌 (ISSN:09167250)

巻号頁・発行日

vol.53, no.3, pp.371-377, 1991-06-15

被引用文献数

2

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マウスの Babesia rodhaini 感染の免疫学的変化を追求できるモデル系を, まず, 薬腺 Diminazene diaceturate (DD)を使い確立した. R. rodhainiの腹腔内(i. p.)接種で有胸腺(nu/+)および無胸腺(nu/nu) BALB/cマウスは急死した. 感染早期にDD処置すると両マウスともに急性死から免れた. 耐過マウスの一部は虫血症を再発したが, 致死的再発は nu/nuマウスのみにみられた. 回復マウスを28日目に10^5感染赤血球(PE)でi. p.に再攻撃すると, nu/+マウスは抵抗したが, nu/nuマウスは防御しなかった. 以上から防御機序に胸腺が関与することが示唆された. 次にnu/+, nu/nuマウスに10^4PEをi. p.接種しDD治療を行い, 28日目に10^5PEをi. p.再攻撃して免疫学的変化を調べた. nu/+マウスは, B. rodhaini可溶性抗原足蹠注射による即時型反応および, 同抗原とプロテインAを用いたELISAによる血清抗体でみた抗体応答が, 10日以降から出現し, 再攻撃後は強い応答がみられた. 一方, nu/nuマウスの血清から抗体は検出されなかった. 遅延型足蹠反応はnu/+マウスに14日目以降に見られたが, 再攻撃後は抑制された. DD注射-再攻撃のnu/+マウスの脾細胞(再攻撃後8日)を, nu/nuマウスに移入し10^4PEでi. p.に攻撃すると, 5匹中3匹のnu/nuマウスは一時的な低い虫血症を示し耐過したが, 残り2匹は重篤な虫血症を伴い早期に死亡した. このモデル系はバベシア免疫に有効な細胞の解析を可能にするものと思われる.

著者

Valeria DE PALMA Alfio MARTELLO Gianluca BACCI Mario RICCIARDI

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.81, no.1, pp.66-70, 2019 (Released:2019-01-08)

参考文献数

16

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In dogs, variation in the branching pattern of renal veins is rare with only few patterns reported. This report describes two unusual anomalies of the renal vein branching patterns in two dogs. In dog 1, a common renal trunk drained both kidneys, in a T-shape pattern, in the caudal vena cava after a long right perirenal course. In dog 2, a common venous trunk branched cranially from the pre-renal segment of an azygos-caudal vena cava venous trunk and divided into the renal veins in a Y-shape pattern. Proper knowledge of the possible anatomical variations in renal venous drainage may be helpful during imaging assessment and surgical planning of several canine diseases involving the abdominal vasculature and retroperitoneal space.

著者

Ai HORI Kazuyuki SUZUKI Masateru KOIWA Kenjirou MIYOSHI Tetsuya NAKADE

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.81, no.1, pp.42-47, 2019 (Released:2019-01-08)

参考文献数

25

被引用文献数

3

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A 6-day-old female Holstein displayed a dome-shaped skull and cardiac murmur on physical examination. Neurological abnormalities included progressive ataxia, decreased pupillary light reflex, and blindness soon after birth. On diagnostic imaging, CT identified expanded ventricles and thyroid hypoplasia on the left side. MRI detected expanded ventricles, especially in the rostral cerebrum at the mesencephalic aqueduct, compared with normal calves, so we suspected hydrocephalus causing stenosis of the mesencephalic aqueduct. Postmortem examination revealed a structure in the mesencephalic aqueduct resembling the “web” type of aqueductal stenosis described in humans. This case report indicates the utility of describing mesencephalic aqueductal stenosis by web and detection of other malformations on CT and MRI for antemortem diagnosis in calves.

著者

Kennosuke SUGIE Tetsuya KOMATSU Eri WATANDO Nanami INABA Kiyoko KATO Daisuke TAKAMATSU Hiroya ITO Tomoyuki SHIBAHARA

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.18-0630, (Released:2019-01-01)

被引用文献数

2

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Five-day-old neonatal piglets presented with debilitation and ananastasia. At the necropsy of one piglet, the apex of the tongue was found to be discolored dark red, and disseminated white foci were found on the cut surface. Many white foci were also found in the lungs and on the serosa of the liver and spleen. Histopathological findings revealed multifocal necrotic glossitis and pneumonia with Gram-negative bacilli. The bacilli were identified as Actinobacillus suis through immunohistochemical, biochemical, and genetic tests, including 16S rRNA gene sequencing. Although A. suis usually causes inflammation in thoracic and abdominal organs, lesions were also found in the tongue in the present case. This study is the first report of glossitis caused by A. suis.