著者
塚越 俊夫 Toshio TSUKAGOSHI 群馬大学医学部産科婦人科学教室 Department of Obstetrics and Gynecology Gunma University School of Medicine
雑誌
日本産科婦人科學會雜誌 = Acta obstetrica et gynaecologica Japonica (ISSN:03009165)
巻号頁・発行日
vol.42, no.12, pp.1655-1662, 1990-12-01

ある矯正施設に収容された女子集団 (15~20歳:平均17.4歳) 141例における性行動とC. trachomatis (以下CT) 感染の関係を疫学的に分析し以下の成績を得た. 1. 初経年齢は, 原発性無月経の1例を除き9~15歳に分布し, 平均12.1歳であった. 2. 全員に性交経歴があり, 初交年齢は11~18歳, 平均13.9歳と低年齢であった. 3. 16例 (11.3%) の子宮頚管材料からCTが分離培養され, Micro Trak法により9例 (6.4%) からCT抗原が検出された. いずれかの方法によるCT抗原陽性者は19例 (13.5%) であった. 4. CT抗原は子宮頚管炎と診断された55例中14例 (25.5%) に陽性であり, 炎症の認められなかった86例からの陽性率5.8%に比べ有意に高率であった (p < 0.001). 5. CT抗原検出と腔トリコモナス症の間に相関が認められた (p < 0.05). 6. CT抗原は低年齢層 (15~17歳) で21.1%と高率に認められ, 年長グループ (18~20歳) での陽性率はわずか4.6%であった (p < 0.01). 7. 57名に妊娠歴 (1~3回) があったが, CT抗原陽性率は妊娠経験のないグループのほうが高率であった(p < 0.05). 8. 血中の抗CTlgG抗体は65例 (46.1%) に証明された.抗CT抗体陽性グループにCT抗原が高率に見出され, かつ抗原と抗体の血清型(immunotype)が一致する例が多かった. このことから血中抗CT抗体は現症のCT感染の結果生じたものであるが, 頚管部へのCT感染に対し, 強い阻止効果を表さないことが示唆された. 9. CTに起因する子宮頚管炎を治療せずに放置した場合, 若年女子では平均56日で自然消失するグループと100日以上に亘って持続感染するグループに分かれることが窺われた.
著者
加藤 正也 今高 城治 岡本 健太郎 谷 有希子 山口 岳史 荻野 恵 土岡 丘 加藤 広行 有阪 治 Masaya Kato George Imataka Kentaro Okamoto Yukiko Tani Takeshi Yamaguchi Kei Ogino Takashi Tuchioka Hiroyuki Kato Osamu Arisaka 獨協医科大学医学部 小児科学 獨協医科大学医学部 小児科学 獨協医科大学医学部 第一外科学 獨協医科大学医学部 第一外科学 獨協医科大学医学部 第一外科学 獨協医科大学医学部 第一外科学 獨協医科大学医学部 第一外科学 獨協医科大学医学部 第一外科学 獨協医科大学医学部 小児科学 Department Of Pediatrics Dokkyo Medical University Department Of Pediatrics Dokkyo Medical University First Department Of Surgery Dokkyo Medical University First Department Of Surgery Dokkyo Medical University First Department Of Surgery Dokkyo Medical University First Department Of Surgery Dokkyo Medical University First Department Of Surgery Dokkyo Medical University First Department Of Surgery Dokkyo Medical University Department Of Pediatrics Dokkyo Medical University
雑誌
Dokkyo journal of medical sciences (ISSN:03855023)
巻号頁・発行日
vol.41, no.2, pp.173-176, 2014-07-25

症例1は6歳女児.インフルエンザ感染症初日に発熱しオセルタミビルを開始.第3病日,右下腹部に限局した圧痛が出現.腹部造影CTで糞石を認め急性虫垂炎と診断.保存的に加療し炎症反応と腹痛は改善した.症例2は5歳女児.第1病日に発熱と腹痛を認め,第3病日に鼻咽腔迅速検査でインフルエンザB型と診断しザナミビル吸入を開始.触診で右下腹部に反跳痛を認め,腹部単純CTで虫垂壁の肥厚と糞石を確認.急性虫垂炎の併発と診断し,第4病日に虫垂切除術を施行.切除虫垂に膿瘍を認め腹腔ドレーンを留置.第5病日に解熱し経過は順調であった.インフルエンザに伴う腹痛では感染に付随する腹痛と断定せず急性虫垂炎の可能性も考慮し腹部CTなどの画像検査を行うことが肝要である.
著者
渡部 弥栄子 今高 城治 斎藤 祥子 岩波 久威 鈴木 紫布 金谷 英明 桑島 成子 有阪 治 Yaeko Watabe George Imataka Shoko Saito Hisatake Iwanami Shiho Suzuki Hideaki Kanaya Shigeko Kuwashima Osamu Arisaka 獨協医科大学医学部 小児科学 獨協医科大学医学部 小児科学 獨協医科大学医学部 小児科学 獨協医科大学医学部 内科学(神経) 獨協医科大学医学部 内科学(神経) 獨協医科大学医学部 脳神経外科 獨協医科大学医学部 放射線科 獨協医科大学医学部 小児科学 Departments Of Pediatrics Dokkyo Medical University School Of Medicine Departments Of Pediatrics Dokkyo Medical University School Of Medicine Departments Of Pediatrics Dokkyo Medical University School Of Medicine Neurology Dokkyo Medical University School Of Medicine Neurology Dokkyo Medical University School Of Medicine Neurosurgery Dokkyo Medical University School Of Medicine Radiology Dokkyo Medical University School Of Medicine Departments Of Pediatrics Dokkyo Medical University School Of Medicine
雑誌
Dokkyo journal of medical sciences (ISSN:03855023)
巻号頁・発行日
vol.41, no.2, pp.177-181, 2014-07-25

Tolosa-Hunt症候群(THS)は先行する片側眼窩部痛と眼球運動障害を生じ,病態は海綿静脈洞の非特異的炎症性肉芽腫病変と推測されている.発症は年間100万人あたり1人前後で,40歳台の成人に多く小児例は稀である.今回,1カ月続く右眼をえぐられる様な頭痛を主訴とした15歳のTHSを報告する.発症後,各種頭痛薬で改善がなく,各種検査を施行し異常がないため心身症に伴う反復する片頭痛と診断された.当院で脳MRIを施行し右内頸動脈の狭窄を認めTHSと確定診断した.プレドニゾロン(PSL)1?mg/kg/dayを朝1回開始し,翌日頭痛は改善した.以降,半年かけてPSLを漸減し再発はない.Tolosa-Hunt syndrome(THS)is characterized by periorbital pain accompanying opthalmoplegia. The pathogenesis is considered to involve non-specific granulomatous inflammation in the cavernous sinus, and the frequency is around one case per year per million people. Symptoms usually develop in adulthood, and pediatric cases are rare. We report herein a case of THS in a 15-year-old girl whose headache was diagnosed as psychosomatic disease in the early stage of the clinical course. Her chief compliant was headache with strong pain in the right eye, continuing for 1 month. Although several medications were trialed to alleviate headaches, no improvement was achieved. Various physical examinations proved uninformative. Headache was therefore tentatively diagnosed as psychosomatic disease associated with migraine. Brain magnetic resonance imaging in our university hospital revealed strangulation of the internal carotid artery, and headache was diagnosed as confirmed THS. Oral administration of prednisolone was started at 1 mg/kg/day, given once in the morning. Headache improved from the next day. Oral therapy with prednisolone was tapered over the course of 6 months and headache did not recur.
著者
及川 伸二 村田 真理子 平工 雄介 川西 正祐 Shinji Oikawa Mariko Murata Yusuke Hiraku Shosuke Kawanishi 三重大学医学部衛生学教室 三重大学医学部衛生学教室 三重大学医学部衛生学教室 三重大学医学部衛生学教室 Department of Hygiene Mie University School of Medicine Department of Hygiene Mie University School of Medicine Department of Hygiene Mie University School of Medicine Department of Hygiene Mie University School of Medicine
出版者
日本環境変異原学会
雑誌
環境変異原研究 = Environmental mutagen research communication (ISSN:09100865)
巻号頁・発行日
vol.23, no.3, pp.207-213, 2001-12-22
参考文献数
33

Reactive oxygen species are capable of causing damage to various cellular constituents, such as DNA, proteins and lipids, leading to carcinogenesis, aging and a number of diseases. We have investigated the sequence specificity of oxidative stress-mediated DNA damage by using ^<32>P-labeled DNA fragments obtained from the human c-Ha-ras-1, p53 and p16 genes. The sequence specificity of DNA damage plays the key role in the mutagenic process, and affects the mutation frequency. Therefore, investigation on sequence specificity of DNA damage would provide clues on the biological significance of DNA damage which in turn may be beneficial for cancer prevention strategy. Here we discuss the mechanisms and sequence specificity of DNA damage caused by various environmental chemicals and UVA-activated photosensitizers in relation to carcinogenesis and aging.
著者
大城 淳一 国吉 孝夫 盛島 浩明 照喜名 重順 城間 健治 新垣 聰 東恩納 厚 新垣 民樹 浦崎 政仁 佐久川 廣 金城 福則 斎藤 厚 Ohshiro Junichi Kuniyoshi Takao Morishima Hiroaki Terukina Shigeyoshi Shiroma Kenji Arakaki Satoshi Higashionna Atsushi Arakaki Tamiki Urasaki Masahito Sakugawa Hiroshi Kinjo Fukunori Saito Atsushi 琉球大学医学部第一内科
出版者
琉球大学医学部
雑誌
琉球大学医学会雑誌 : 医学部紀要 = Ryukyu medical journal (ISSN:02891530)
巻号頁・発行日
vol.11, no.1, pp.28-34, 1989

Sulfasalazine and corticosteroids have been used for the treatment of ulcerative colitis. Recently, it is investigated to use metronidazole for treatment of ulcerative colitis. We tried to use metronidazole for three patients with ulcerative colitis , to whom neither sulfasalazine nor corticosteroids were effective. In case 1 the patient was 37-year-old female,to whom conticosteroids had been ineffective. After treatment by metronidazole together with corticosteroids, the symptoms were improved. In case 2 the patient was 74-year-old female, who had relapsed during treatment with sulfasalazine. Treatment with metronidazole alone resulted in the remission of disease. In case 3 the patient was 32-yearold female, to whom the treatment with sulfasalazine and corticosteroids enema had been ineffecitve. By use of metronidazole together with sulfasalazine, she had remission. It seems that metronidazole is useful for the treatment of ulcerative colitis, especially in patients who did not respond to other drugs.
著者
正村 啓子 岩本 美江子 市原 清志 東 玲子 藤澤 怜子 杉山 真一 國次 一郎 奥田 昌之 芳原 達也 Keiko MASAMURA Mieko IWAMOTO Kiyoshi ICHIHARA Reiko AZUMA Reiko FUJISAWA Shinichi SUGIYAMA Ichirou KUNITSUGU Masayuki OKUDA Tatsuya HOBARA 山口大学医学部保健学科・医学科 山口大学医学部保健学科 山口大学医学部保健学科 山口大学医学部保健学科・医学科 山口大学医学部保健学科・医学科 山口大学医学部医学科 山口大学医学部医学科 山口大学医学部医学科 山口大学医学部医学科 Faculty of Health Sciences Faculty of Medicine Yamaguchi University School of Medicine Faculty of Health Science Yamaguchi University School of Medicine Faculty of Health Science Yamaguchi University School of Medicine Faculty of Health Sciences Faculty of Medicine Yamaguchi University School of Medicine Faculty of Health Sciences Faculty of Medicine Yamaguchi University School of Medicine Faculty of Medicine Yamaguchi University School of Medicine Faculty of Medicine Yamaguchi University School of Medicine Faculty of Medicine Yamaguchi University School of Medicine Faculty of Medicine Yamaguchi University School of Medicine
出版者
山口大学医学会
雑誌
山口医学 (ISSN:05131731)
巻号頁・発行日
vol.52, no.1, pp.13-21, 2003-04-30
参考文献数
34
被引用文献数
1

The purpose of this study was to investigate the stress level and resources of student's nurse engaged in clinical practice and examine the relationships between their stress and daily life. Data were obtained by self-report questionnaires from 63 nurse students who had just finished the clinical practice component of a Junior College Diploma Course. A 59-item questionnaire, that investigated the student's nurse stress (55-items) and their daily life (4-items), as well as a demographic data questionnaire was used. Data were analyzed via t-tests and factor analysis. The findings revealed that the student nurses found the time required to write practical records after school and conflicts with nurses to be the most stressful aspect of their clinical practice experience. Factor analysis revealed that the stress level of the students who were living with family was lower than that those living by themselves (p<0.1). In addition, the stress level of the students having interchange with other students' was significantly lower than that of the students having little interchange with other students (p<0.05). These findings suggest that the stress level of nursing students may be decreased through decreased paperwork requirements of the practical records form and by encouraging interchange between students.
著者
中田 真依 服部 ユカリ Mai Nakata Yukari Hattori 北海道文教大学人間科学部看護学科 旭川医科大学医学部看護学科
出版者
北海道文教大学
雑誌
北海道文教大学研究紀要 (ISSN:13493841)
巻号頁・発行日
no.39, pp.39-50, 2015-03

本研究の目的は,急性心筋梗塞で入院中にせん妄を体験した患者の思いを明らかにすることである.闘病記録をnarrative と位置づけ,せん妄に関連のある内容を記録文書データとして収集し,テーマ分析方法を用いて分析した.分析の結果,シークエンス毎に3 つのコアテーマ,テーマ,サブテーマに分類された.コアテーマの《せん妄を発症するまでの思い》からは10 テーマ,《せん妄からの回復過程における思い》からは8 テーマ,《せん妄体験の想起と総括》からは4 テーマが導かれ,表面化されず患者自身しか知り得ない様々な思いが明らかになった.せん妄発症前は束縛恐怖など複数の苦痛や不安が存在し,せん妄発症後は断片的なせん妄の記憶,精神の弱さなどの否定的な思い,長期的なせん妄の余韻,自責の念や葛藤が存在していた.また,患者は家族や医療職者に対する感謝の思いを抱き,時間経過とともに病を克服しながら人生における貴重な体験と意味づけ,narrative を総括していた.これらのことから,患者が抱く様々な思いの存在に着目し,共感的姿勢で関わる重要性および,術前にせん妄の知識を提供するなどの予防的対応,早期に回復できるような個人に適した看護の必要性が示唆された.The objective of this study is to understand patient feelings after experiencing delirium whilehospitalized due to acute myocardial infarction. Using hospital diaries as narratives, we collected descriptions related to delirium as documented data, and analyzed these using thematic analysis. The analysis allowed the data to be classified into three core themes, themes, and sub-themes. From the core themes, we extracted ten themes from "feelings up to the development of delirium", eight from "feelings during the process of recovery from the delirium", and four from "recollections and summary of the delirium experience", which showed a variety of internalized feelings which only the patient could know. It was found that the patient suffered from different fears and anxieties such as the fear of being restrained before developing delirium. After delirium had developed, the patient had only a fragmental memory of the delirium, negative attitudes such as weakness of will, aftereffects after long-term delirium, feelings of remorse, and mental conflicts. The patient showed feelings of gratitude towards the family and medical professionals and overall viewed the experience as a positive life experience in overcoming the illness in the course of time. These findings suggest the importance of providing nursing care withempathy and paying attention to the variety of feelings of patients, as well as the necessity of proactive action, including providing information of delirium before surgery, and personalized nursing care to enable a speedy recover.
著者
田中 愛子 後藤 政幸 岩本 晋 李 恵英 杉 洋子 金山 正子 奥田 昌之 國次 一郎 芳原 達也 Aiko TANAKA Masayuki GOTOH Susumu IWAMOTO Keiei LI Yoko SUGI Masako Kanayama Masayuki Okuda Ichiro KUNITSUGU Tatsuya HOBARA 山口大学医学部環境情報系・公衆衛生学講座 和洋女子大学短期大学部 元山口県立大学看護学部 岡山大学大学院法医生命倫理学講座 山口大学医学部環境情報系・公衆衛生学講座 山口大学医学部環境情報系・公衆衛生学講座 山口大学医学部環境情報系・公衆衛生学講座 山口大学医学部環境情報系・公衆衛生学講座 山口大学医学部環境情報系・公衆衛生学講座 Department of Public Health. and. Human Environment and Preventive Medicine Yamaguchi University School of Medicine Department of Health and Nutrition Wayo Women's University Formerly of School of Nursing Yamaguchi Prefectural University Department of Legal and Bioethics Graduate School of the University of Okayama Department of Public Health. and. Human Environment and Preventive Medicine Yamaguchi University School of Medicine Department of Public Health. and. Human Environment and Preventive Medicine Yamaguchi University School of Medicine Department of Public Health. and. Human Environment and Preventive Medicine Yamaguchi University School of Medicine Department of Public Health. and. Human Environment and Preventive Medicine Yamaguchi University School of Medicine Department of Public Health. and. Human Environment and Preventive Medicine Yamaguchi University School of Medicine
出版者
山口大学医学会
雑誌
山口医学 (ISSN:05131731)
巻号頁・発行日
vol.50, no.4, pp.697-704, 2001-08-31
参考文献数
21
被引用文献数
1

In order to explore how to provide death education according to age groups, we examined the differences in the awareness of death between the adolescent and the middle age groups. A questionnaire survey was conducted using the Death Concern Scale. The subjects were students (n=627) aged between 19 and 29 (i.e. the adolescent group), company workers (n=149) and visiting nurses (n=94) aged between 30 and 64 (i.e. the middle age group). First, the question items were analyzed by content analysis and confirmed by factor analysis. Two factors were extracted from the Death Concern Scale:"thinking about death " and "anxiety and fear of death". Secondly, the data from both age groups were analyzed and compared by using the Mean Structure Model. The factor "thinking about death" had a greater value for the adolescent group than for the middle age group. There was no significant difference between the two groups in terms of the factor "anxiety and fear of death". These results imply that death education carries more importance for the adolescent group than for the middle age group.