著者
馬場 駿吉 高坂 知節 稲村 直樹 佐藤 三吉 鈴木 茂 遠藤 里見 石戸谷 雅子 小野寺 亮 山田 公彦 大久 俊和 荒井 英爾 鈴木 雅明 大山 健二 粟田口 敏一 戸川 清 岡本 美孝 松崎 全成 寺田 修久 喜多村 健 石田 孝 馬場 廣太郎 島田 均 森 朗子 池田 聖 金子 敏郎 今野 昭義 山越 隆行 石井 哲夫 窪田 市世 鍋島 みどり 田口 喜一郎 石山 哲也 中野 雄一 中村 英生 五十嵐 文雄 古川 仭 作本 真 山下 公一 久保田 修 宇佐神 篤 伊藤 博隆 鈴木 元彦 間宮 紳一郎 横田 明 加藤 薫 大屋 靖彦 河合 〓 岩田 重信 横山 尚樹 井畑 克朗 瀧本 勲 稲福 繁 坂倉 康夫 鵜飼 幸太郎 雨皿 亮 山田 弘之 坂倉 健二 平田 圭甫 伊藤 由紀子 村上 泰 竹中 洋 山下 敏夫 久保 伸夫 中井 義明 大橋 淑宏 阪本 浩一 村田 清高 平沢 昌子 原田 康夫 森 直樹 白根 誠 多田 渉 小林 優子 竹林 脩文 河野 嘉彦 夜陣 紘治 平田 思 宮脇 修二 津田 哲也 山下 隆司 二階堂 真史 柿 音高 永澤 容 増田 游 後藤 昭一 西岡 慶子 折田 洋造 東川 康彦 武 浩太郎 進 武幹 前山 忠嗣 百田 統洋 堤 昭一郎 茂木 五郎 川内 秀之 松下 太 吉村 弘之 高田 順子 石川 哮 定永 恭明 大山 勝 松崎 勉 坂本 邦彦 廣田 常治 内薗 明裕 鯵坂 孝二 中島 光好
出版者
The Society of Practical Otolaryngology
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.88, no.3, pp.389-405, 1995-03-01
被引用文献数
13 12

The efficacy and safety of Kampo preparation Sho-seiryu-to were studied in a joint double-blind trial in comparison with a placebo. The study was carried out on 220 patients with perennial nasal allergy at 61 hospitals. Granules in a dose of 3 g were administered 3 times daily for 2 weeks. Moderate to high improvement was recorded in 44.6% of the treated patients and in 18.1% of those receiving placebo. The difference is significant (p <0.001). Side effects were noted in 6.5% of the treated patients and in 6.4% of the controls (not a significant deference). The side effects were mild and had no influence on the daily life of the patients.
著者
池岡 博之 大橋 淑宏 丸岡 健一 古下 博之 中井 義明 小野山 靖人
出版者
一般社団法人 日本耳鼻咽喉科学会
雑誌
日本耳鼻咽喉科学会会報 (ISSN:00306622)
巻号頁・発行日
vol.88, no.11, pp.1562-1566, 1985-11-20 (Released:2008-03-19)
参考文献数
21

In order to examine the effects of irradiation on the nasal epithelium, rabbits received 200kV hard X-ray irradiation at 3, 000 rad to their nasal septum. The nasal mucosa after the irradiation was examined with scanning and transmission electron microscopy in a time-course manner. Immediately after the irradiation, few morphological changes were observed on the nasal epithelium with scanning electron microscopy, while transmission electron microscopy disclosed some morphological changes such as vacuolation and ballooning of epithelial cells, and enlargement of intercellular space. 2 weeks after the irradiation, sporadically affected changes were observed. The affected signs of the epithelial cells were observed at the wider area according to the course of time after the irradiation. 4 weeks after the irradiation, stratified arrangement of non-ciliated cells or undifferentiated cells were noted in an extensive area of the nasal mucosa 8 weeks after the irradiation, the nasal epithelium were chiefly consisted of undifferentiated cells. Accordingly, the following conclusions were derived from the present investigation; 1) Irradiation affected the nasal ciliary epithelium. 2) The damage of the nasal epithelium by irradiation was not recovered easily.
著者
江暗 裕介 中井 義明 大橋 淑宏 金 朋郁
出版者
The Society of Practical Otolaryngology
雑誌
耳鼻咽喉科臨床 (ISSN:00326313)
巻号頁・発行日
vol.85, no.2, pp.227-231, 1992

A 35-year-old male patient visited our outpatient clinic with sudden onset of right ear fullness. Right tubal stenosis was considered to be responsible for his complaint. A roughsurfaced flat tumor was found close to the right Rosenmuller's fossa, and biopsy was performed immediately under fiberscopy. Whether his hearing loss was due to a conductive or sensorineural disturbance was not conclusively determined because the audiogram was complicated. The tumor was diagnosed histopathologically as not malignant but inflammatory, "epithelioid granulosis in the pharyngeal tonsil". Physical examinations did not support either sacoidosis or active tuberculosis. The final diagnosis, based on a retrospective study of his lesion, was old epipharyngeal tuberculosis and sudden deafness.