著者
大槻 マミ太郎 照井 正 小澤 明 森田 明理 佐野 栄紀 髙橋 英俊 小宮根 真弓 江藤 隆史 鳥居 秀嗣 朝比奈 昭彦 根本 治 中川 秀己
出版者
公益社団法人 日本皮膚科学会
雑誌
日本皮膚科学会雑誌 (ISSN:0021499X)
巻号頁・発行日
vol.121, no.8, pp.1561-1572, 2011-07-20 (Released:2014-11-13)

Clinical use of TNFα (tumor necrosis factor α) inhibitors, adalimumab and infliximab, for psoriasis began in January 2010 when an additional indication for this disease was approved. In January 2011, an interleukin-12/23 p40 (IL-12/23 p40) inhibitor, ustekinumab, was newly approved as the third biologic agent with an indication for psoriasis. All of these biologic agents are expected to exhibit excellent efficacy against not only psoriasis but also psoriatic arthritis, and to contribute to the improvement of quality of life (QOL) of psoriatic patients. At the same time, however, they require safety measures to prevent adverse drug reactions such as serious infections. We therefore decided to prepare this Guideline/Safety Manual for the Use of Biologic Agents in Psoriasis (The 2011 Version) by revising that for the use of TNFα Inhibitors prepared by the Biologics Review Committee of the Japanese Dermatological Association in February 2010. In this new unified version for all three biologic agents including ustekinumab, requirements for clinical facilities for the use of biologic agents, contents of safety measures against reactivation of tuberculosis and hepatitis B, and recommendable combination therapies with biologic agents, have been renewed and added. This guideline/safety manual has been prepared to assist dermatology specialists experienced in clinical practice of psoriasis to use biologic agents safely and properly.
著者
根本 治代
出版者
昭和女子大学
雑誌
學苑 (ISSN:13480103)
巻号頁・発行日
vol.832, pp.96-106, 2010-02-01

This study aims to clarify incentives and disincentives, as recognized by professionals who provide consultation and support for persons with disabilities, in inter-professional work. The study looks at professionals' handling of difficult cases and discusses ideal approaches to inter-professional work for strengthening professionals' expertise. Through interviews, the following incentives were identified:(1)"sense of responsibility" and "way of networking" at an individual level,(2)"philosophy sharing," "information shar- ing," "consensus building," and "role clarification" at a team level, and(3)"collaboration with related governmental/private organizations" at an organizational level. The disincentives, which professionals identified as obstacles preventing the continuation of the supportive relationship, include:(1)"different perceptions of situations" in their relationship with social service users,(2)"insufficient communication/information," "low social status of the profes- sions," and "lack of skill as a professional" in their relationship with other professionals in several different fields, and(3)"issues of organizational structure" and "issues arising from the legal system's boundaries" in their relationship with governmental/private organizations. To strengthen expertise of professionals, approaches based on incentives in inter-professional work are needed.
著者
小川 基彦 萩原 敏且 岸本 寿男 志賀 定祠 吉田 芳哉 古屋 由美子 海保 郁夫 伊藤 忠彦 根本 治育 山本 徳栄 益川 邦彦
出版者
社団法人 日本感染症学会
雑誌
感染症学雑誌 (ISSN:03875911)
巻号頁・発行日
vol.75, no.5, pp.353-358, 2001-05-20 (Released:2011-02-07)
参考文献数
13
被引用文献数
3 3

ツツガムシ病の全国の発生状況について, 1998年に実施した調査票をもとに解析を行った. 1998年の患者は416人で, 24の都道府県で発生し, 過去3年間とほぼ同数であった. 患者には性差は認められず, 51歳以上の割合が723%と高かった. また, 患者の32.0%および1a5%が農作業および森林作業に従事しており, 高い割合を占めた. 患者の発生は, 九州地方で全体の56.2%を占め, 続いて関東地方の20.7%, 東北・北陸地方の19.0%となり, これらの地方だけで全国の959%の発生があった.また, 月別にみると, 東北, 北陸地方では4~6月と10~12月の両方に発生がみられ, 九州, 関東などそれ以外の地域では10~12月に発生が多くみられ, 地方ごとの流行時期が示された. さらに, 九州地方における流行株を患者血清の抗体価から推測した結果, 新しい血清型のKawasaki, Kuroki株がこの順に多く大部分を占め, 地域差は認められなかった. また, この地方では標準株 (Kato, Karp, Gilliam株) ではなく, 新しい血清型を使用しないと診断できない患者が24人認められた. この結果から, 他の地域でも流行株の調査および診断に使用する株を検討する必要が示唆された. 今回初めてツツガムシ病のわが国における全体像が明らかになり, 今後の発生予測, 適切な診断と治療および予防を行うにあたり極めて重要な情報が得られた.
著者
根本 治
出版者
信州大学人文学部
雑誌
人文科学論集
巻号頁・発行日
vol.19, pp.29-40, 1985-03-05
著者
根本 治子
出版者
日本法政学会
雑誌
法政論叢 (ISSN:03865266)
巻号頁・発行日
vol.43, no.2, pp.39-51, 2007

Although the environment of care should be improved by laws, such as 'Pflegeversicherung' and 'Low of Prevention of Elder-Abuse,' murder cases relating to care, on the contrary, have been increasing all over the entire country. The examination of these murder cases shows that there would have been a bighpossibility to have prevented them if the medical staff and the welfare staff had cooperated closely with each other. The role of 'the special member,' who supports care, is very important from the point of view that his/her judgment is deeply concerned with the life of the family who cares for older family members. And the role of the family is also important at the place of medical treatment and welfare. The family itself should realize that the subject of care is a family member, and more attention should be paid on how medical treatment and welfare can support the family. On the other hand, in many trials, the public prosecutor and the lawyer argueonly about what kind of sentence should be given to the defendant, without investigating the background and the true nature of the incident: why the family caretaker has committed homicide. This paper examines the importance of cooperation at the actual care site between the persons concerned in the field of medical treatment and welfare, and the Administration of Justice, focusing on the trial of the murder case which is relating to care, where the writer has attended.
著者
根本 治代
出版者
法政大学
雑誌
現代福祉研究 (ISSN:13463349)
巻号頁・発行日
vol.5, pp.167-182, 2005-03-31