著者

Uyeda Seiya Horai Ki-iti

出版者

東京大学地震研究所

雑誌

東京大学地震研究所彙報 (ISSN:00408972)

巻号頁・発行日

vol.41, no.1, pp.83-107, 1963-06-30

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Eight sets of new data on the terrestrial heat flow have been added to the existing five sets of data in Kanto and Chubu Districts, or the central part of Japan. Of the eight new localities, seven are in metal mines and one in a natural gas field. Expressing the geothermal gradient ΔT/ΔZ in ℃/100 m, and the heat flow in 10-6 cal/cm2 sec, the present data can be summarized as: Mobara: ΔT/ΔZ=1.85, Q=0.54 Ashio: ΔT/ΔZ=3.57, Q=2.23 Chichibu: ΔT/ΔZ=1.90, Q=1.34 Kamioka: ΔT/ΔZ=2.77, Q=1.80 Nakatatsu: ΔT/ΔZ=2.90, Q=1.95 Kune: ΔT/ΔZ=1.97, Q=1.60 (Honzan) ΔT/ΔZ=2.17, Q=1.44 (Nako) Minenosawa: ΔT/ΔZ=2.82, Q=1-79 Combined with previous data, the above figures indicate the following facts: a) Heat flow on the Pacific coast side of Kanto District is, without exception, small (Q<1.00); b) High heat flow region, known on the Japan Sea coast side of Tohoku District (Q>2.00) extends to the north-western part of Kanto District and possibly down to the Izu-Mariana Arc. This high heat flow region apparently coincides with that of Tertiary volcanism of Japan, c) Heat flow in Chubu District is higher than the world's average (Q = 1.2~1.4) but not very much. This high value may be accounted for by the relatively thick crust of the District.1.1957年以来,地震研究所においては,日本全土における地殼熱流量分布の決定が試みられてきた.1961年以降には,日本鉱業協会,日本石炭協会,天然ガス鉱業会,帝国石油株式分社,東京大学地質学教室の渡辺武男教授,久野久教授他の大きな御協力を得て,全国の鉱山,炭礦,油田,ガス田等においてやや組織的な地熱測量が行なわれた.地球熱学第8報乃至第12報は,その結果の報告である,この仕事では,樋口重雄氏,山川一郎氏(日本鉱業協会),佐久洋氏,佐野孝一氏(石炭協会),橋爪義雄氏(天然ガス鉱業会),柴宮博氏(帝国石油株式会社),他多くの方々,並びに,各現場での数多の方々の御指導,御援助を得た.記して深甚の謝意を表明する.岩石熱伝度測定のための試料研磨にっいては,地震研究所渡辺佐技官に多大のお世話になつた.なお,この研究は地震研究所力武常次教授の全面的御援助の下に終始したものである.従来,関東地方,中部地方には,信頼し得る地殼熱流量,Q,の測定は5個であつた.すなわち,Qを10-6cal/cm2 secで表して,日立(Q=0.94~1.21),鹿島(Q=0.76),勝田(Q=0.91),東京大学構内(Q=0.74),笹子トンネル(Q=2.06),である.今回は,新たに,8個の測定が加えられた,その結果概要は以下の通りである.千葉県茂原: Q=0.54栃木県足尾: Q=2.23埼玉県秩父: Q=1.34岐阜県神岡: Q=1.80福井県中竜: Q=1.95静岡県久根: Q=1.60,(久根坑)Q=1.44,(名合坑)静岡県峰之沢: Q=1.79本文,第1図を参照しつつ,上記結果を検討すると,以下のことが明らかである.a)関東地方太平洋側では,地殻熱流量は例外なく小さい(Q<1.0).b)従来察知されていた,東北地方日本海側の地殻熱流量の大きい地域(Q>2.0)の延長が,関東地方西北部にもみられ,所謂,第三紀火成活動帯と一致している.この地域は,更に南にのび,伊豆マリアナ弧につながる可能性がある.c)中部地方の大部分は,世界的平均熱流量(Q=1.2~1.4)よりは大きい値を示すが,Q=2.0には至らない程度である.なお,この地方では,既報,草津白根地熱地帯での結果のごとく,熱流量が局地的異常を示した例もあるが,伊豆大島火山,丹那盆地,清越鉱山等,おそらくは地下水の流動のために,信頼するに足る地温勾配の得られない場合もあつた.各測点での記録は以下のごとくである.

著者

Mari VAINIONPÄÄ Marja RAEKALLIO Elina TUHKALAINEN Hannele HÄNNINEN Noora ALHOPURO Maija SAVOLAINEN Jouni JUNNILA Anna HIELM-BJÖRKMAN Marjatta SNELLMAN Outi VAINIO

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.74, no.12, pp.1539-1544, 2012 (Released:2012-12-28)

参考文献数

30

被引用文献数

1 15

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The objective of this study was to compare the method of thermography by using three different resolution thermal cameras and basic software for thermographic images, separating the two persons taking the thermographic images (thermographers) from the three persons interpreting the thermographic images (interpreters). This was accomplished by studying the repeatability between thermographers and interpreters. Forty-nine client-owned dogs of 26 breeds were enrolled in the study. The thermal cameras used were of different resolutions-80 × 80, 180 × 180 and 320 × 240 pixels. Two trained thermographers took thermographic images of the hip area in all dogs using all three cameras. A total of six thermographic images per dog were taken. The thermographic images were analyzed using appropriate computer software, FLIR QuickReport 2.1. Three trained interpreters independently evaluated the mean temperatures of hip joint areas of the six thermographic images for each dog. The repeatability between thermographers was >0.975 with the two higher-resolution cameras and 0.927 with the lowest resolution camera. The repeatability between interpreters was >0.97 with each camera. Thus, the between-interpreter variation was small. The repeatability between thermographers and interpreters was considered high enough to encourage further studies with thermographic imaging in dogs.

著者

Hak-Hyun RYU Byung-Jae KANG Sung-Su PARK Yongsun KIM Gyu-Jin SUNG Heung-Myong WOO Wan Hee KIM Oh-Kyeong KWEON

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.74, no.12, pp.1617-1630, 2012 (Released:2012-12-28)

参考文献数

54

被引用文献数

21 99

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Previous animal studies have shown that transplantation of mesenchymal stem cells (MSCs) into spinal cord lesions enhances axonal regeneration and promotes functional recovery. We isolated the MSCs derived from fat, bone marrow, Wharton’s jelly and umbilical cord blood (UCB) positive for MSC markers and negative for hematopoietic cell markers. Their effects on the regeneration of injured canine spinal cords were compared. Spinal cord injury was induced by balloon catheter compression. Dogs with injured spinal cords were treated with only matrigel or matrigel mixed with each type of MSCs. Olby and modified Tarlov scores, immunohistochemistry, ELISA and Western blot analysis were used to evaluate the therapeutic effects. The different MSC groups showed significant improvements in locomotion at 8 weeks after transplantation (PP<0.05). Transplanted MSCs survived for 8 weeks and reduced IL-6 and COX-2 levels, which may have promoted neuronal regeneration in the spinal cord. Our data suggest that transplantation of MSCs promotes functional recovery after SCI. Furthermore, application of UCSCs led to more nerve regeneration, neuroprotection and less inflammation compared to other MSCs.

著者

Feng Xu Aoki Sinya Fukaya Hidenori Hashimoto Shoji Kaneko Takashi Noaki Jun-ichi Shintani Eigo JLQCD Collaboration

出版者

American Physical Society

雑誌

Physical Review Letters (ISSN:00319007)

巻号頁・発行日

vol.109, no.18, pp.182001, 2012-11

被引用文献数

20 8

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We perform a nonperturbative calculation of the π0→γγ transition form factor and the associated decay width using lattice QCD. The amplitude for a two-photon final state, which is not an eigenstate of QCD, is extracted through a Euclidean time integral of the relevant three-point function. We utilize the all-to-all quark propagator technique to carry out this integration as well as to include the disconnected quark diagram contributions. The overlap fermion formulation is employed on the lattice to ensure exact chiral symmetry on the lattice. After examining various sources of systematic effects, except for a possible discretization effect, we obtain Γπ0→γγ=7.83(31)(49)  eV for the pion decay width, where the first error is statistical and the second is our estimate of the systematic error.

著者

Sang-Keun HAN KeeChan PARK Young-Hyun JUN Bai-Sun KONG

出版者

The Institute of Electronics, Information and Communication Engineers

雑誌

IEICE TRANSACTIONS on Electronics (ISSN:09168516)

巻号頁・発行日

vol.E95-C, no.11, pp.1824-1826, 2012-11-01

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This paper introduces novel high-speed and low-power boosted level converters for use in dual-supply systems. The proposed level converters adopt a voltage boosting at the gate of pull-down transistors to improve driving speed and reduce contention problem. Comparison results in a 0.13-µm CMOS process indicated that the proposed level converters provided up to 70% delay reduction with up to 57% power-delay product (PDP) reduction as compared to conventional level converters.

著者

Okjin KIM Kyung-Suk KIM

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.67, no.1, pp.121-123, 2005 (Released:2005-02-05)

参考文献数

7

被引用文献数

8 13 19

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A male 8-year-old Yorkshire Terrier dog with unilateral cryptorchism was presented for investigation of reduced appetite and multifocal alopecia. Abdominal sonography and radiography demonstrated abnormal enlargement of left testicle in abdominal cavity. Both of the retroperitoneal cryptorchid testicle and the other contralateral testicle were removed surgically. The concentrations of testosterone and estradiol in blood collected from the jugular vein and the two spermatic veins were evaluated and the results revealed high estradiol concentration. The retroperitoneal cryptorchid testicle was enlarged, firm, bulging sphere mass. The cut surface revealed homogeneous white color and lobulation by septa. The contralateral testicle in scrotum showed atrophic testicle and enlarged epididymis. Histopathologically, the retroperitoneal cryptorchid testicle was diagnosed as seminoma. We thought that hyperesterogenemia and alopecia in this case was probably related with his seminoma, although high correlations between Sertoli cell tumor and alopecia have been reported. To our knowledge, this report may be a rare case of seminoma with hyperesterogenemia and alopecia.

著者

Ji-Seon YOON Tomohiko MINAMI Yasuko TAKIZAWA Maiko SEKIGUCHI Atsushi YABUZOE Kaori IDE Koji NISHIFUJI Toshiroh IWASAKI

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.72, no.11, pp.1513-1516, 2010 (Released:2010-11-30)

参考文献数

12

被引用文献数

1 2 1

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Two dogs of juvenile-onset skin diseases with involvement of extremities were examined by histopathological, immunohistochemical and ultrastructural analyses. Clinically, both cases showed alopecia and crusts on the face and extremities. Case 1 showed histopathology of dermo-epidermal separation. Ultrastructural analysis revealed that the clefts were recognized between hemidesmosomes and lamina densa. In case 2, histopathology showed follicular atrophy, vacuolar degeneration at lower epidermis and masseter muscle degeneration, without remarkable ultrastructural abnormalities in basement membrane zone of the skin. Thus, the findings in case 1 were compatible to those in junctional epidermolysis bullosa, while those in case 2 were compatible to dermatomyositis-like disease. Combination of histopathological and ultrastructural analyses was useful to distinguish the diseases in two dogs.

著者

Hiroyuki TSUDA Yutaka OHSHIMA Hiroshi NOMOTO Ken-ichi FUJITA Eiji MATSUDA Masaaki IIGO Nobuo TAKASUKA Malcolm A. MOORE

出版者

日本薬物動態学会 会長/日本薬物動態学会 DMPK編集委員長

雑誌

Drug Metabolism and Pharmacokinetics (ISSN:13474367)

巻号頁・発行日

vol.19, no.4, pp.245-263, 2004 (Released:2004-09-29)

参考文献数

152

被引用文献数

132 154

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Increasing attention is being paid to the possibility of applying cancer chemopreventive agents for individuals at high risk of neoplastic development. For this purpose by natural compounds have practical advantages with regard to availability, suitability for oral application, regulatory approval and mechanisms of action. Candidate substances such as phytochemicals present in foods and their derivatives have been identified by a combination of epidemiological and experimental studies. Plant constituents include vitamin derivatives, phenolic and flavonoid agents, organic sulfur compounds, isothiocyanates, curcumins, fatty acids and d-limonene. Examples of compounds from animals are unsaturated fatty acids and lactoferrin. Recent studies have indicated that mechanisms underlying chemopreventive potential may be combinations of anti-oxidant, anti-inflammatory, immune-enhancing, and anti-hormone effects, with modification of drug-metabolizing enzymes, influence on the cell cycle and cell differentiation, induction of apoptosis and suppression of proliferation and angiogenesis playing roles in the initiation and secondary modification stages of neoplastic development. Accordingly, natural agents are advantageous for application to humans because of their combined mild mechanism. Here we review naturally occurring compounds useful for cancer chemprevention based on in vivo studies with reference to their structures, sources and mechanisms of action.

著者

Yasunari KAYASHIMA Keiko YAMANASHI Ayaka SATO Shigenori KUMAZAWA Kimiko YAMAKAWA-KOBAYASHI

出版者

(社)日本農芸化学会

雑誌

Bioscience, Biotechnology, and Biochemistry (ISSN:09168451)

巻号頁・発行日

pp.120496, (Released:2012-11-07)

被引用文献数

19 10

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Royal jelly (RJ), a honeybee-derived product, has been found to possess developmental and physiological bioactivity in the fruit fly, Drosophila melanogaster, but little is known about the in vivo bioactivity of freeze-dried RJ (FDRJ) powder, which is another form of RJ processed for human use. To address this, we used Drosophila as a model animal to examine the effects of FDRJ in multicellular organisms. When flies were reared on food supplemented with FDRJ, the developmental time from larva to adult was shortened, the adult male lifespan was prolonged, and female fecundity was increased without any significant morphological alterations. Moreover, the expression of dilp5, an insulin-like peptide, its receptor InR, and the nutrient sensing molecule TOR, the target of rapamycin, was significantly increased in FDRJ-fed female flies as compared with ones reared on standard and on protein-enriched food. These findings suggest that like RJ, FDRJ maintains its bioactivity even after processing from RJ, what is expected to have bioactivity for multicellular organisms, including humans.

著者

Olivares-Tirado Pedro

巻号頁・発行日

2012

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Thesis (Ph. D.)--University of Tsukuba, (A), no. 6258, 2012.3.23

著者

Lee Sang-Min Byun Hi-Ryong Tanaka Hiroshi L.

出版者

American Meteorological Society

雑誌

Journal of applied meteorology and climatology (ISSN:15588424)

巻号頁・発行日

vol.51, no.6, pp.1087-1098, 2012-06

被引用文献数

29 1

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The drought climate of Japan from 1902 to 2009 was analyzed using an effective drought index (EDI). Drought regions were identified by hierarchical cluster analysis using drought characteristics (duration, severity, and onset and end dates) obtained from 50 observation stations. The results indicated that droughts could be divided into four groups (G1–G4) that reflected the local climate. The four groups were related to precipitation as follows. The summer rainy season affected groups G2–G4, in which droughts occurred mainly during spring and summer and were relieved before and after the rainy season. The G1 group was not affected by the summer rainy season and droughts were spread evenly throughout the year; it even had cases of droughts relieved by winter snow. All groups included dry conditions over the 108-yr period, and the driest conditions occurred in the late twentieth century. The statistical analysis of drought data showed that a total of 23 country-wide droughts occurred and that the most extreme droughts occurred in 1939–41 and 1984–85, with an EDI of −1.55. In addition, four dry seasons (1939–45, 1997–98, 1994–97, and 2005–09) were found using regime shift analysis. Regional droughts occurred 54, 54, 49, and 59 times in groups G1–G4, respectively. On average, short-term droughts with a duration shorter than 6 months occurred 3.5 times per decade, whereas long-term droughts extending over 1 yr occurred 0.3 times per decade. The drought duration and intensity were used to calculate the statistical return period of country-wide droughts. The 1939–41 drought had the longest return period, at 104.7 yr. The 1987–88 and 1995–97 droughts had return periods of 65.9 and 65.5 yr, respectively.

著者

Hitoshi HATAI Mitsuru IBA Daisuke KOJIMA Chun-Ho PARK Yasuhiko TSUCHIDA Toshifumi OYAMADA

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.12-0446, (Released:2012-12-10)

被引用文献数

1 6

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A 13-year-old castrated male Labrador retriever dog presented with a mass caudal to the first molar of his left mandible. Although the tumor was excised, a recurrent tumor was detected one month later and resected. Both tumors displayed invasive growth and were composed of neoplastic proliferation arranged in irregular lobules, nests and cords continuous with mucosal epithelium. The most prominent feature of the tumors was the presence of many proliferating spindle cells admixed with palisading basal-like cells, acanthocytes and stellate cells. In immunohistochemical examinations, the spindle cells were found to be positive for vimentin; cytokeratin AE1/AE3, 5/6, 14 and 19; and p63. The other neoplastic cells were positive for all of these markers shown above except vimentin. Based on these findings, the tumors were diagnosed as spindle cell ameloblastic carcinoma.

著者

Tatsuya Suzuki Kenzo Oba Yoshimasa Igari Noriaki Matsumura Kentaro Watanabe Shoko Futami-Suda Hiroko Yasuoka Motoshi Ouchi Kazunari Suzuki Yoshiaki Kigawa Hiroshi Nakano

出版者

日本医科大学医学会

雑誌

Journal of Nippon Medical School (ISSN:13454676)

巻号頁・発行日

vol.74, no.5, pp.338-343, 2007 (Released:2007-10-26)

参考文献数

20

被引用文献数

45 75

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Background: Colestimide has been reported to lower blood glucose levels in patients with type 2 diabetes complicated by hypercholesterolemia. Aim: To examine the mechanism by which colestimide decreases plasma glucose levels in the above patients. Methods: A total of 16 inpatients with type 2 diabetes complicated by hypercholesterolemia received colestimide for 1 week after their plasma glucose levels stabilized. We measured plasma glucose, serum immunoreactive insulin (IRI), serum lipid, plasma glucagon, and plasma glucagon-like peptide-1 (GLP-1) levels. These variables at baseline and 1 week of colestimide administration were compared. Results: Preprandial plasma glucose levels (baseline: 132 ± 33 mg/dL vs. completion: 118 ± 43 mg/dL, P=0.073) tended to decrease after colestimide administration, while 1-hr postprandial plasma glucose levels (baseline: 208 ± 49 mg/dL vs. completion: 166 ± 30 mg/dL, P<0.001) and 2-hr postprandial plasma glucose levels (baseline: 209 ± 56 mg/dL vs. completion: 178 ± 39 mg/dL, P=0.015) decreased significantly at 1 week of colestimide administration. The 2-hr postprandial plasma GLP-1 level was significantly (P=0.015) higher at 1 week of colestimide administration as compared with the baseline level, while there were no significant changes in preprandial and 1-hr postprandial plasma GLP-1 levels. Conclusions: The GLP-1-increasing activity of colestimide may explain, at least in part, the mechanism of its blood glucose-lowering activity in patients with type 2 diabetes complicated by hypercholesterolemia.

著者

So Young Lee Jai-Ok Kim Jiunn-Ger Li

出版者

日本建築学会(AIJ)、大韓建築学会(AIK)、中国建築学会(ASC) 編集事務局:AIJ jaabe(at)aij.or.jp

雑誌

Journal of Asian Architecture and Building Engineering (ISSN:13467581)

巻号頁・発行日

vol.10, no.1, pp.133-140, 2011-05-13 (Released:2011-05-13)

参考文献数

36

被引用文献数

5 25 2

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The perception of crowding and the shopping environment can influence consumers' decisions on where to shop as well as their buying decision and store image. The purpose of the study is to investigate the effects of store layout design and factors about the consumer on the perception of store crowding and in turn analyze the impact of perceived crowding on shopping behavior and store image. Surveys were conducted at two discount stores in Taipei City, Taiwan. A total of 532 questionnaires were used for analysis. Spatial crowding was assessed using physical area factors including floor layout designs, aisle table area, and ceiling height. Perceptions of crowding resulted from the spatial arrangement, while human crowding contributed to the feeling of overall store crowding. Among a store's physical area factors, aisle table area most strongly impacts the overall degree of perceived store crowding, followed by free-flow layout and grid layout areas. Among various individual factors, age and prior experience of crowding are significantly related to perceived crowding. The results showed that perceptions of spatial crowding had a negative relationship to promotional image while perceptions of human crowding had a positive relationship to discount store image.

著者

Haengbok CHEON Wooshin CHOI Youngjae LEE Donghoon LEE Juhyung KIM Ji-Houn KANG Kijeong NA Jinhwa CHANG Dongwoo CHANG

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.74, no.11, pp.1461-1467, 2012 (Released:2012-12-01)

参考文献数

30

被引用文献数

5 19 1

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The aim of this study was to assess age-related changes and anatomic variation in trabecular bone mineral density (tBMD) using quantitative computed tomography (QCT) in normal cats. Seventeen normal cats were included in this study and divided into the following 3 age groups:6 years (n=3). A computed tomographic scan of each vertebra from the 12th thoracic to the 7th lumbar spine and the pelvis was performed with a bone-density phantom (50, 100 and 150 mg/cm3, calcium hydroxyapatite, CIRS phantom®). On the central transverse section, the elliptical region of interest (ROI) was drawn to measure the mean Hounsfield unit (HU) value. Those values were converted to equivalent tBMD (mg/cm3) by use of the bone-density phantom and linear regression analysis (r2 >0.95). The mean tBMD value of the thoracic vertebrae (369.4 ± 31.8 mg/cm3) was significantly higher than that of the lumbar vertebrae (285 ± 58.1 mg/cm3). The maximum tBMD occurred at the T12, T13 and L1 levels in all age groups. There was a statistically significant difference in the mean tBMD value among the 3 age groups at the T12 (PPP=0.013), respectively. The present study suggests that age-related changes and anatomic variation in tBMD values should be considered when assessing tBMD using QCT in cats with bone disorders.

著者

Lee-Shuan LIN Yuko KAYASUGA Nobuyuki SHIMOHATA Hiroyuki KAMATA Shigeki SUZUKI Ryosuke ECHIGO Manabu MOCHIZUKI Ung-Il CHUNG Nobuo SASAKI

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.74, no.11, pp.1511-1516, 2012 (Released:2012-12-01)

参考文献数

41

被引用文献数

2 2

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Trehalose has several novel anti-inflammatory and cell-protective functions. We hypothesized that lyophilized aspirin/trehalose could decrease the severity of aspirin-induced gastropathy. Thirteen dogs were assigned into aspirin, lyophilized aspirin/trehalose, and control groups, and the gastric lesions were assessed on gastroscopy with the modified Lanza scale. Another 6 dogs were used to measure the plasma aspirin concentration by high-performance liquid chromatography after aspirin or lyophilized aspirin/trehalose administration. The results indicated that lyophilized aspirin/trehalose induced less gastric ulceration than aspirin despite maintaining therapeutic concentrations of plasma aspirin in both the groups. Lyophilized aspirin/trehalose might be a solution to decrease aspirin-induced gastropathy.

著者

Tamaoka Katsuo Sakai Hiromu Kawahara Jun-ichiro Miyaoka Yayoi Lim Hyunjung Koizumi Masatoshi

出版者

Springer

雑誌

Journal of Psycholinguistic Research (ISSN:00906905)

巻号頁・発行日

vol.34, no.3, pp.281-332, 2005-05

被引用文献数

9 42

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The present study investigated scrambling effects on the processing of Japanese sentences and priority information used among thematic roles, case particles and grammatical functions. Reaction times for correct sentence decisions were significantly prolonged for scrambled active sentences with transitive verbs in the first experiment and with ditransitive verbs in the second experiment. Errors were made with scrambled sentences more than canonical sentences in both experiments, which suggested that scrambling effects were apparent in active sentences. Passive sentences in the third experiment indicated that canonical order defined based on case particles, not thematic roles, was more quickly and accurately identified than scrambled order. Potential sentences in the fourth experiment and causative sentences in the fifth experiment indicated that the processing of scrambled sentences based on grammatical functions, but not on case particles, required longer reaction times and resulted in higher error rates than canonical sentences. Consequently, scrambling effects in the present study indicated that neither thematic roles nor case particles can provide fully-satisfactory information for canonical phrase order, and that only grammatical functions offer satisfactory information in all types of sentences.

著者

福井 博泰 新庄 エルサ-マルガリータ 梁川 良

出版者

社団法人日本獣医学会

雑誌

日本獸醫學雜誌 (ISSN:00215295)

巻号頁・発行日

vol.42, no.2, pp.177-186, 1980-04-25

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レプトスピラの抗原変異株を家畜から分離しようとして, Leptospira interrogans血清型canicolaを子犬に, pomonaをSPF豚に接種し, 血液および腎臓をhomologousな免疫血清を加えた寒天平板に培養した. 2〜4週後に寒天上に発育したコロニーを, 大, 中および小型コロニーに区分し, それぞれいくつかずつを無作為に単離し, 沈降素吸収試験によるスクリーニングでその抗原性を親株と比較した. Canicolaの抗原変異株は感染犬10頭中7頭の血液および7頭中3頭の腎臓から得られた. 変異株は血液および腎臓由来の大型コロニーに多数, また血液由来の中および小型コロニーに少数認められた. 変異株は接種菌液からも分離されたが, 感染犬血液からはそれよりも有意に高い割合で分離された。他方pomonaの抗原変異株は感染豚5頭中2頭の血液のみにおいて小型コロニーに認められた. 大型コロニーは豚からは出現しなかった. 変異株は接種菌液からも分離されたが感染豚血液からはそれより有意に高い割合で分離された. 変異株の抗原性は交差凝集素吸収試験などによっても親株とは明らかに異なり, 同じ株由来の変異株はその抗原性が互いに類似した. 以上の結果は, 用いられた株には少数の抗原変異株が含まれており, その割合は実験感染後3〜7日目の犬や豚の血液において有意に上昇したことを示している.

著者

Yamazaki Takeshi Ishikawa Ken-ichi Kuramashi Yoshinobu Ukawa Akira

出版者

American Physical Society

雑誌

Physical review D (ISSN:15507998)

巻号頁・発行日

vol.86, no.7, pp.074514, 2012-10

被引用文献数

92

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We calculate the binding energies for multinucleon bound states with the nuclear mass number less than or equal to 4 in 2+1 flavor QCD at the lattice spacing of a=0.09  fm employing a relatively heavy quark mass corresponding to mπ=0.51  GeV. To distinguish a bound state from attractive scattering states, we investigate the volume dependence of the energy shift between the ground state and the state of free nucleons by changing the spatial extent of the lattice from 2.9 to 5.8 fm. We conclude that 4He, 3He, deuteron and dineutron are bound at mπ=0.51  GeV. We compare their binding energies with those in our quenched studies and also with several previous investigations.

著者

Michelle B. CHRISTENSEN Rebecca LANGHORN Amelia GODDARD Eva B. ANDREASEN Elena MOLDAL Asta TVARIJONAVICIUTE Jolle KIRPENTEIJN Sabrina JAKOBSEN Frida PERSSON Mads KJELGAARD-HANSEN

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.12-0404, (Released:2012-11-28)

被引用文献数

4 8

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Canine serum amyloid A (SAA) is a useful diagnostic marker of systemic inflammation. A latex agglutination turbidimetric immunoassay (LAT) was validated for automated measurements. The aim of the study was to evaluate the clinical applicability of SAA measured by the LAT. SAA was measured in 7 groups of dogs with and without systemic inflammation (n=247). Overlap performance was investigated. Diagnostic performance was compared to body temperature and leukocyte markers. Clinical decision limits for SAA were estimated. In dogs with neurological, neoplastic, or gastrointestinal disorders (n=143), it was investigated whether a higher proportion of SAA positive dogs could be detected in cases of complications with risk of systemic inflammation. Significantly higher concentrations of SAA were measured in dogs with (range [48.75; 5,032 mg/l]), compared to dogs without systemic inflammation [0; 56.4 mg/l]. SAA was a more sensitive and specific marker of systemic inflammation [area under the receiver-operating characteristic curve (AUC) 1.00], compared to body temperature (0.6) and segmented neutrophils (best performing leukocyte marker, 0.84). A clinical decision limit of 56.4 mg/l was established giving close to perfect discrimination between dogs with and without systemic inflammation. Higher proportions of SAA-positive dogs were observed in dogs with neurological, neoplastic, and gastrointestinal disorders with complications known to increase risk of systemic inflammation, compared to uncomplicated cases. The automated LAT makes SAA applicable as a relevant diagnostic marker of systemic inflammation in dogs for routine random-assess real-time use in a general clinical setting.