著者

Yoshihito SETO Hitoshi YOKOYAMA Tsuyoshi NAKATANI Haruo ANDO Nobumitsu TSUNEMATSU Yoshinori SHOJI Kenichi KUSUNOKI Masaya NAKAYAMA Yuto SAITOH Hideo TAKAHASHI

出版者

Meteorological Society of Japan

雑誌

気象集誌. 第2輯 (ISSN:00261165)

巻号頁・発行日

vol.96A, pp.35-49, 2018 (Released:2018-02-19)

参考文献数

16

被引用文献数

4

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The relationships between the occurrence of intense rainfall and the convergence of surface winds and water vapor concentration for typical heavy-rainfall cases were examined using data from July to August in 2011-2013, obtained from high-density meteorological observations in Tokyo, Japan. Additionally, the temporal variations in wind convergence and water vapor between days with and without heavy rainfall events were compared. Corresponding to heavy-rainfall areas, the convergence of surface winds tended to increase for several tens of minutes prior to the heavy rainfall. The peak of convergence was observed 10-30 min before the heavy-rainfall occurrence, and convergence continued to increase for approximately 30 min until the convergence peak time. Around the heavy-rainfall area, the increase in the water vapor concentration index coincided with the increase in convergence. From these results, by monitoring the temporal variations and distributions of these parameters using a high-density observation network, it should be possible to predict the occurrence of heavy rainfall rapidly and accurately.

著者

Hiroaki KAWASE Hidetaka SASAKI Akihiko MURATA Masaya NOSAKA Noriko N. ISHIZAKI

出版者

(公社)日本気象学会

雑誌

気象集誌. 第2輯 (ISSN:00261165)

巻号頁・発行日

vol.93, no.5, pp.571-580, 2015 (Released:2015-11-17)

参考文献数

33

被引用文献数

3 19

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We investigate future changes in winter precipitation around Japan and their uncertainties using the downscalings of a non-hydrostatic regional climate model (NHRCM) with 20-km grid spacing according to global climate projections. The global climate projections were conducted by the atmospheric general circulation model with three patterns of sea surface temperature changes in the Coupled Model Intercomparison Project Phase 5 under the Representative Concentration Pathway 8.5. Moreover, three cumulus convective parameterizations were applied in the present and future climate experiments. The ensemble mean of nine future NHRCM experiments shows decreases in the winter precipitation on the coast of the Sea of Japan and over the Pacific Ocean in the south of the Japanese archipelago. The former decrease in precipitation results from a weakened winter monsoon. The latter corresponds to changes in extratropical cyclone number around Japan, which have a large uncertainty. On the other hand, winter precipitation increases over the northernmost part of Japan (Hokkaido) and the northeastern Asian continent. The strengthened northwesterly around Hokkaido, which results from the reduction of sea ice in the Sea of Okhotsk, causes increased precipitation in the inland area of Hokkaido. In addition, moistening due to global warming relates to increased precipitation in extremely cold regions. These signals are common to most experiments.

著者

下楠 昌哉 シモクス マサヤ Masaya SHIMOKUSU

雑誌

静岡文化芸術大学研究紀要 = Shizuoka University of Art and Culture bulletin

巻号頁・発行日

vol.3, pp.23-31, 2003-03-31

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本論では、ブラム・ストーカー(1847-1912)の初期の小説作品である『蛇峠』(1890)、『ドラキュラ』(1897)、『海の神秘』(1902)における風景描写と、登場人物たちが利用する交通機関との関係性を扱う。鉄道の登場とその速度、および一九世紀半ばのイギリス本土における鉄道網の確立と旅行の大衆化は、ヴィクトリア時代の人々の視覚に重大な変容をもたらし、風景を見る者から隔絶した次々と移り変わる「パノラマ」として捉える感覚を、人々に遍く実装させるに至った。ストーカーの三作品はどれも旅行者を主人公としており、それらの作品における風景描写は、風景とそれをまなさす者との間の断絶と、その断絶を生み出した列車の速度の影響をはっきりと表象している。テクノロジーの発展と人間の知覚の変容との関係性を記録したメディアとして、ストーカーの小説を読み込んでゆくこと。それが本論で試みられているプラクシスである。This paper deals with the relationships between scenery descriptions and means of transport in three early works of Bram Stoker (1847-1912): The Snake's Pass (1890), Dracula (1897) and The Mystery of the Sea (1902). The invention of the train and its high velocity caused a critical change of perception. The establishment of the British railroad system and the democratization of tourism in the middle of the 19th century then allowed the perception to prevail among Victorians. People came to perceive landscapes through the windows of trains as a string of swiftly-changing "panoramas," which the seeing subjects were completely dissociated from what they saw. All protagonists of the three novels of Stoker are travelers. The scenery descriptions in the stories represent the gap between the landscapes and the subjects viewing them. The speed of characters' movements are also deeply related to the gap. The critical praxis attempted in this paper is to read Stoker's novels closely as media recording the relationships between technological developments and the change of human perception in the 19th century.

著者

Daisuke MIYAKOSHI Hiroyuki SENBA Mitsumori SHIKICHI Masaya MAEDA Ryo SHIBATA Kazuhiro MISUMI

出版者

日本ウマ科学会

雑誌

Journal of Equine Science (ISSN:13403516)

巻号頁・発行日

vol.27, no.2, pp.67-76, 2016 (Released:2016-06-21)

参考文献数

14

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This study aimed to evaluate the influence of radiographic abnormalities of 2-year-old Thoroughbred horses that were listed at in-training sales in Japan, on whether they started to race or not at 2–3 years of age. Radiographs of 850 2-year-old Thoroughbreds in the in-training sales repository from 2007 to 2010 were reviewed, and 26 categories of radiographic abnormalities were found. Forty-three horses (5.1%, 43/850) did not start a race at 2–3 years of age. In accordance with the racing results for this age category, as determined by Fisher’s exact test and multiple logistic regression analysis, none of the radiographic abnormalities were significantly related to failure to start a race. At 2 years of age, 198 horses (23.3%, 198/850) did not start a race. Horses with enlargement of the proximal sesamoid bones in the fore (9 of 19 horses) and hind limbs (5 of 9 horses) did not start a race at the age of 2 years, and fewer of these horses (fore, P=0.021; hind, P=0.030) started a race at the age of 2 years compared with the population of horses without these radiographic abnormalities. These results suggest that identification of radiographic enlargement of the proximal sesamoid bones during training sales could derail the racing debut of horses at the age of 2 years. However, this might not necessarily indicate a poor prognosis and resulting in retirement from racing at 2–3 years of age.

著者

Karin Takeda Masaya Oda Takemichi Okada Hitoshi Yamazaki Makoto Ohbu Masaaki Watanabe Hiroaki Yokomori

出版者

一般社団法人 日本内科学会

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

vol.55, no.10, pp.1293-1297, 2016 (Released:2016-05-15)

参考文献数

12

被引用文献数

1 3

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A 64-year-old man seeking treatment for a common cold was admitted to our hospital due to symptoms of general fatigue and liver dysfunction. A thorough history review revealed that the patient had recently started taking an over-the-counter (OTC) drug. Drug-induced lymphocyte stimulation tests were positive. Serum markers for autoimmune hepatitis (AIH) were particularly elevated. Liver biopsy revealed spotty necrosis and ceroid-pigmented Kupffer cells and piecemeal necrosis with multiple plasma cells. He responded to corticosteroids, thus suggesting the presence of an immune-mediated component associated with the liver injury. Liver injury after using OTCs should be included in the differential diagnosis for chronic hepatitis with features of AIH.

著者

Masaya IGASE Takako SHIMOKAWA MIYAMA Satoshi KAMBAYASHI Yumiko SHIMOYAMA Hiroko HIRAOKA Yumi HIRATA Miki IWATA Kenji BABA Takuya MIZUNO Masaru OKUDA

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.15-0156, (Released:2015-12-04)

被引用文献数

7

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A 10-year-old female spayed mixed breed cat with a subcutaneous mass on the right hind limb-was revealed with bimodal monoclonal gammopathy composed of IgA by immunoelectrophoresis and immunofixation. Approximately 1 month after referral, the cat died due to renal failure. Postmortem immunohistopathologic evaluation of the subcutaneous mass revealed neoplastic cell proliferation of plasma cells and giant myeloma cells. Neoplastic cells were also present in the liver and spleen. These results led to the diagnosis of a rare case of feline myeloma-related disorders with extramedullary plasmacytoma infiltrating in multiple locations. This report emphasizes the necessity to accumulate cases with similar clinicopathologic findings in the future.

著者

Kenjiro FUKUSHIMA Reina FUJIWARA Kie YAMAMOTO Hideyuki KANEMOTO Koichi OHNO Masaya TSUBOI Kazuyuki UCHIDA Naoaki MATSUKI Ryohei NISHIMURA Hajime TSUJIMOTO

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.15-0077, (Released:2015-06-27)

被引用文献数

1 27

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Little information is available regarding triple-phase computed tomography (CT) of canine pancreatic insulinoma. A few case reports with small numbers of cases have indicated that hyper-attenuation in the arterial phase was a common finding on multi-phasic CT in dogs with insulinoma. Our purpose was to clarify the characteristic findings of dogs with insulinoma on triple-phase CT. Nine dogs with insuolinoma that underwent triple-phase CT were included in the present study. Attenuation patterns in the arterial phase indicated hypo-attenuation in 4 cases and hyper-attenuation in 2 cases. In the remaining 3 cases, 1 case showed hypo-attenuation and 1 case showed hyper-attenuation in the pancreatic phase, and 1 case presented hyper-attenuation in the later phase. Altogether, 5 cases showed hypo and 4 cases showed hyper-attenuation in at least one phase. The enhancement pattern was homogenous in 7 cases and heterogeneous in 2 cases. Tumor margins were well-defined in 5 cases and ill-defined in 4 cases. Capsule formation was present in 5 cases and absent in 4 cases. In conclusion, it is important to note that hypo-attenuation was as common as hyper-attenuation in dogs with insulinoma in triple-phase CT in at least one phase. Additionally, mass lesions were most conspicuous not only in the arterial phase but in the pancreatic and later phases in some cases. Therefore, it is important to perform triple-phase CT and notice about variable findings for the detection of canine pancreatic insulinoma.

著者

Yoshinori TAKEUCHI Masashi TAKAHASHI Masaya TSUBOI Yasuhito FUJINO Kazuyuki UCHIDA Koichi OHNO Hiroyuki NAKAYAMA Hajime TSUJIMOTO

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.74, no.8, pp.1057-1062, 2012 (Released:2012-09-03)

参考文献数

28

被引用文献数

2 20

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A Japanese domestic long-hair cat of about 8 years of age was presented with vomiting and hematochezia and was found to have significant hypereosinophilia. Bone marrow aspiration revealed moderate increases of eosinophilic lineages. Histopathological examination revealed mild eosinophilic and epitheliotropic T-lymphocytic infiltrations in the duodenum. Although the cat remained asymptomatic with only prednisolone administration, the cat presented with hematemesis, weight loss, and severe anorexia 512 days after the initial presentation. Subsequently, gastrointestinal perforation developed, and the cat died on Day 536. Histopathological examination of autopsy specimens revealed mixed cellular infiltration including eosinophils and neoplastic lymphocytes in the intestinal lymph nodes, intestine, liver, spleen, and pancreas. Immunohistochemical examination supports a diagnosis of intestinal T-cell lymphoma with severe hypereosinophilic syndrome.

著者

Toru Naganuma Keigo Dote Masaya Kato Shota Sasaki Kentaro Ueda Yasuyuki Kono Yoshikazu Watanabe Masato Kajikawa Haruko Yokoyama

出版者

一般社団法人 日本内科学会

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

vol.48, no.6, pp.433-436, 2009 (Released:2009-03-16)

参考文献数

17

被引用文献数

3

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A 65-year-old man who had undergone retropubic prostatectomy for prostate adenocarcinoma presented with sudden dyspnea and chest pain. Contrast-enhanced multi-slice computed tomography (MSCT) revealed thrombi in the left internal jugular vein (IJV) and in branches of the right pulmonary artery. Ultrasonography showed that the thrombus which occluded the left IJV was hypoechoic and mobile. After beginning anticoagulant therapy, he again presented with dyspnea and transient hypotension. MSCT and ultrasonography showed that the IJV thrombus had moved and caused a new embolism of the left pulmonary artery branch. This is a rare case of a patient who experienced non-catheter-related thrombosis of the IJV.

著者

Masaya TSUBOI Kazuyuki UCHIDA Tetsuya IDE Mizue OGAWA Takehiko INAGAKI Shinji TAMURA Miyoko SAITO James K. CHAMBERS Hiroyuki NAKAYAMA

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.12-0224, (Released:2012-11-01)

被引用文献数

5

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Canine polyneuropathy is a neurological disorder characterized by a dysfunction of multiple peripheral nerves. The etiology of the disease is diverse; it may occur in cases of infectious, immune-mediated, or hereditary conditions or in association with endocrinopathy, neoplasm, or chemical intoxication. It is often difficult to determine the etiology through clinical symptoms. The aim of this study is to investigate pathological differences among three canine polyneuropathy cases with each presumably having a different etiology. Cases included a 13-month-old female border collie (Dog No.1), a 21-month-old male chihuahua (Dog No.2), and an 11-year-old male beagle (Dog No.3). Clinical examinations revealed hindlimb ataxia and sensory loss in Dog No.1, forelimb paralysis and vertebral pain in Dog No.2, and paddling-gait and hypothyroidism in Dog No.3. Histopathologically, axonal swelling and pale myelin were observed in Dog No.1. Giant axons mimicking giant axonal neuropathy were obvious in Dog No.2. Dog No.3 showed atrophic axons and severe interstitial edema. Distributions of peripheral nerve lesions coincided with respective clinical symptoms. According to their clinical and pathological features, Dogs No.1 and No.2 were suspected of hereditary polyneuropathy, while Dog No.3 seemed to have hypothyroidism-associated polyneuropathy. As each case demonstrated unique pathological features, different pathogeneses of peripheral nerve dysfunction were suggested.

著者

Yoshinori TAKEUCHI Masashi TAKAHASHI Masaya TSUBOI Yasuhito FUJINO Kazuyuki UCHIDA Koichi OHNO Hiroyuki NAKAYAMA Hajime TSUJIMOTO

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.1203220798, (Released:2012-03-28)

被引用文献数

6 20

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A Japanese domestic long-hair cat of about 8 years of age was presented with vomiting and hematochezia and was found to have significant hypereosinophilia. Bone marrow aspiration revealed moderate increases of eosinophilic lineages. Histopathological examination revealed mild eosinophilic and epitheliotropic T-lymphocytic infiltrations in the duodenum. Although the cat remained asymptomatic with only prednisolone administration, the cat presented with hematemesis, weight loss, and severe anorexia 512 days after the initial presentation. Subsequently, gastrointestinal perforation developed, and the cat died on Day 536. Histopathological examination of autopsy specimens revealed mixed cellular infiltration including eosinophils and neoplastic lymphocytes in the intestinal lymph nodes, intestine, liver, spleen, and pancreas. Immunohistochemical examination supports a diagnosis of intestinal T-cell lymphoma with severe hypereosinophilic syndrome.

著者

Soichiro Nagao Yohei Yabuuchi Kosuke Tanaka Yoshiki Morihisa Takuya Kobayashi Shinsuke Akiyama Gensho Tanke Masaya Wada Shuko Morita Satoko Inoue Hiroshi Tei Daisuke Yamashita Tetsuro Inokuma

出版者

The Japanese Society of Internal Medicine

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

pp.2857-23, (Released:2023-11-27)

参考文献数

28

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A 52-year-old man who had been using a proton pump inhibitor (PPI) and a potassium-competitive acid blocker (P-CAB) for 14 years underwent esophagogastroduodenoscopy and was found to have three neuroendocrine tumors (NETs) in the gastric body. Following detailed examinations, parietal cell dysfunction was excluded, and the NETs did not meet the criteria for the Rindi classification types I-III. The lesions were ultimately considered to be associated with the long-term use of the PPI and P-CAB. We performed endoscopic submucosal dissection of the lesions, with no recurrence or new lesions noted after discontinuation of the PPI and P-CAB.

著者

Mitsuyo Hori Yusuke Kawai Koichiro Noguchi Kohei Nakamura Masaya Shimada Hitoshi Iwahashi Tomoyuki Nakagawa

出版者

Japanese Society for Food Science and Technology

雑誌

Food Science and Technology Research (ISSN:13446606)

巻号頁・発行日

pp.FSTR-D-23-00098, (Released:2024-01-10)

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From traditional Gifu ayu-narezushi, Leuconostoc, Latilactobacillus, and Enterococcus were isolated as dominant genera. Isolated strains of Leuconostoc mesenteroides showed high growth inhibition activity against Staphylococcus aureus and Escherichia coli. The isolated strain, Enterococcus lactis EC52, could produce γ-aminobutyric acid (GABA). These results indicated that Enterococcus lactis and Leuconostoc mesenteroides were lactic acid bacteria, which have GABA-producing and antimicrobial activities, respectively, in traditional Gifu ayu-narezushi.

著者

Kota Kera Shohei Makino Risako Takeda Aoi Shimeno Masaya Hojo Sadahiro Hamasaki Akihito Endo Masumi Iijima Tsutomu Nakayama

出版者

Japanese Society for Food Science and Technology

雑誌

Food Science and Technology Research (ISSN:13446606)

巻号頁・発行日

pp.FSTR-D-23-00189, (Released:2023-12-27)

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The astringency of persimmon fruits is a significant factor for consumers and the nutritional industry. To date, astringents, such as polyphenols, specifically persimmon condensed tannins, have been assessed using polyphenol quantification assays, such as the Folin–Ciocalteu method, based on their reducing power. However, these methods are influenced by the presence of other reducing substances. In this study, we developed a cost-effective liposome turbidity analysis using a portable visible spectrophotometer based on the interaction between liposomes and astringents. Authentic astringents, such as catechins and theaflavin-3-O-gallate, were analyzed, and their half-maximal effective concentrations (EC50) were calculated. These results indicated that the affinity to the membrane was similar to that of astringency, as determined by sensory analysis. Additionally, the EC50 values of partially purified tannins from non-astringent and astringent persimmons were calculated. In conclusion, we determined the application methods to assess astringent persimmon fruits with and without the removal of astringency.

著者

Yuji Matsuwaki Takashi Muramatsu Yukio Ozaki Takashi Uwatoko Takuo Toriya Hidemaro Takatsu Yu Yoshiki Masataka Yoshinaga Masato Ishikawa Masaya Ohota Hideaki Ota Hideo Izawa

出版者

Fujita Medical Society

雑誌

Fujita Medical Journal (ISSN:21897247)

巻号頁・発行日

pp.2023-006, (Released:2023-11-29)

参考文献数

25

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Objective: To examine the clinical outcomes of optical coherence tomography (OCT)-guided percutaneous coronary intervention (PCI) in patients presenting with ST-segment elevation myocardial infarction (STEMI).Methods: We retrospectively investigated 533 consecutive patients who underwent primary PCI for STEMI between June 2016 and December 2020. The primary endpoint was a target lesion failure (TLF; defined as a composite of cardiac death, target vessel myocardial infarction, or target lesion revascularization). Propensity score (PS) matching was performed to allow direct comparison of OCT-guided and intravascular ultrasound (IVUS)-guided PCI.Results: Patients in the OCT group (n=166) were younger than those in the IVUS group (n=367) and had a significantly higher left ventricular ejection fraction and estimated glomerular filtration rate. Killip class IV and left main stem disease were more common in the IVUS group. The median peak creatine kinase level was comparable between the two groups (1953 U/L vs 1603 U/L). A significantly larger amount of contrast was used in the OCT group (200 mL vs 165 mL; p<0.001). The cumulative incidence of TLF during a median follow-up of 2.2 years did not differ significantly between OCT and IVUS groups (9.6% vs 13.6%; p=0.221) but cardiac mortality was significantly higher in the IVUS group (8.7% vs 3.6%; p=0.047). After PS matching (n=161 in each group), there was no significant between-group difference in TLF or any other clinical outcome measures.Conclusions: OCT-guided PCI demonstrated clinical outcomes in patients with STEMI that were comparable to those of IVUS-guided PCI despite considerable differences in background characteristics.

著者

Akihito SHIMAZU Ko MATSUDAIRA Jan DE JONGE Naoya TOSAKA Kazuhiro WATANABE Masaya TAKAHASHI

出版者

National Institute of Occupational Safety and Health

雑誌

Industrial Health (ISSN:00198366)

巻号頁・発行日

vol.54, no.3, pp.282-292, 2016-05-31 (Released:2016-06-10)

参考文献数

54

被引用文献数

32 36

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This study examined whether a higher level of psychological detachment during non-work time is associated with better employee mental health (Hypothesis 1), and examined whether psychological detachment has a curvilinear relation (inverted U-shaped pattern) with work engagement (Hypothesis 2). A large cross-sectional Internet survey was conducted among registered monitors of an Internet survey company in Japan. The questionnaire included scales for psychological detachment, employee mental health, and work engagement as well as for job characteristics and demographic variables as potential confounders. The hypothesized model was tested with moderated structural equation modeling techniques among 2,234 respondents working in the tertiary industries with regular employment. Results showed that psychological detachment had curvilinear relations with mental health as well as with work engagement. Mental health improved when psychological detachment increased from a low to higher levels but did not benefit any further from extremely high levels of psychological detachment. Work engagement showed the highest level at an intermediate level of detachment (inverted U-shaped pattern). Although high psychological detachment may enhance employee mental health, moderate levels of psychological detachment are most beneficial for his or her work engagement.

著者

Ikuya Yamada Atsushi Tanaka Seiji Oda Yuichi Okazaki Fumito Toda Yuta Kato Yuta Kizawa Masaya Oshita Manami Goto Amane Morimura Asuka Ochi Kaoru Toda Wencong Wang Hajime Yamamoto Hidekazu Ikeno Shunsuke Yagi

出版者

The Japan Institute of Metals and Materials

雑誌

MATERIALS TRANSACTIONS (ISSN:13459678)

巻号頁・発行日

vol.64, no.9, pp.2097-2104, 2023-09-01 (Released:2023-08-25)

参考文献数

37

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Chemical substitution is an effective way to improve electrocatalytic properties in transition metal oxides. We investigate the synergistic effect between Fe4+ and Co4+ ions on the catalytic activity for oxygen evolution reaction (OER) in the Fe–Co-mixed perovskite oxide CaFe1−xCoxO3. The OER activity of CaFe1−xCoxO3 is substantially increased by small amounts of Co (Fe) doping into CaFeO3 (CaCoO3), leading to the superiority compared to the pure Fe and Co perovskite oxides. The x dependences of the OER overpotential and specific activity for CaFe1−xCoxO3 (0.05 ≦ x ≦ 0.95) are expressed by constant offset from the weighted average between CaFeO3 and CaCoO3, which can be interpreted to be the synergistic effect between Fe4+ and Co4+ ions on OER activity. The absence of the optimum x for the highest activity for CaFe1−xCoxO3 contrasts with the volcano-like plots reported in various mixed-metal oxides. First-principle calculations using the special quasirandom structure models on CaFe1−xCoxO3 (x = 0.03–0.5) demonstrate that about half the amount of Fe4+ is electronically activated to possess smaller charge-transfer energies, corroborating the enhancement of catalytic activity in CaFe1−xCoxO3. These findings provide new insight into the synergistic effects in complex transition metal oxide catalysts.

著者

Hiroshi FUJIWARA Masaya KAWAGUCHI Daiki TAKIZAWA Hiroaki YAMAMOTO

出版者

The Institute of Electronics, Information and Communication Engineers

雑誌

IEICE TRANSACTIONS on Fundamentals of Electronics, Communications and Computer Sciences (ISSN:09168508)

巻号頁・発行日

vol.E106-A, no.9, pp.1100-1110, 2023-09-01

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The bin packing problem is a problem of finding an assignment of a sequence of items to a minimum number of bins, each of capacity one. An online algorithm for the bin packing problem is an algorithm that irrevocably assigns each item one by one from the head of the sequence. Gutin, Jensen, and Yeo (2006) considered a version in which all items are only of two different sizes and the online algorithm knows the two possible sizes in advance, and gave an optimal online algorithm for the case when the larger size exceeds 1/2. In this paper we provide an optimal online algorithm for some of the cases when the larger size is at most 1/2, on the basis of a framework that facilitates the design and analysis of algorithms.

著者

Ryota Hyodo Yasuo Takehara Ayumi Nishida Masaya Matsushima Shinji Naganawa

出版者

Japanese Society for Magnetic Resonance in Medicine

雑誌

Magnetic Resonance in Medical Sciences (ISSN:13473182)

巻号頁・発行日

vol.22, no.3, pp.273-281, 2023 (Released:2023-07-01)

参考文献数

44

被引用文献数

1 1

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Purpose: To elucidate MRI features of primary hepatic mucosa-associated lymphoid tissue (MALT) lymphoma, particularly, the “speckled enhancement” on gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced MRI.Methods: The institutional review board approved this retrospective observational study and waived informed consent. Using our picture archiving and communication systems and electronic medical records, five patients histopathologically diagnosed as hepatic MALT lymphoma and clinically confirmed as primary lesions who had undergone dynamic contrast-enhanced (DCE)-CT and DCE-MRI with Gd-EOB-DTPA were identified from September 2009 to December 2020. Two radiologists assessed their CT and MRI data in consensus with a pathologist’s advice.Results: Overall, five lesions in five patients were included in this study. Precontrast CT showed hypoattenuation in all lesions. In the arterial phase of DCE-CT, four lesions (80%) showed hyperattenuation, whereas all lesions showed iso- to hypoattenuation in the delayed phase. A vessel penetration sign was also observed in all lesions. On MRI, all lesions showed hypointensity on T1-weighted images, hyperintensity on T2-weighted images, and restricted diffusion on diffusion-weighted images. Both DCE-CT and DCE-MRI with Gd-EOB-DTPA showed similar enhancement patterns, except for the hepatocyte phase. Notably, however, four out of five lesions showed characteristic “speckled enhancement” that refers to punctate positive enhancements within the low signal lesions on the hepatobiliary phase of Gd-EOB-DTPA-enhanced MRI pathologically confirmed to be hepatocyte clusters that remained in the tumor.Conclusion: Primary hepatic MALT lymphomas were characterized by arterial phase enhancement, restricted diffusion, vessel penetration sign, and more specifically “speckled enhancement” in the hepatobiliary phase of DCE-MRI with Gd-EOB-DTPA.

著者

Masaya Takabayashi Yuta Hirakawa Takeshi Kakegawa Yoshihiro Furukawa

出版者

GEOCHEMICAL SOCIETY OF JAPAN

雑誌

GEOCHEMICAL JOURNAL (ISSN:00167002)

巻号頁・発行日

pp.GJ23012, (Released:2023-08-01)

被引用文献数

2

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The spontaneous formation of ribonucleotides on prebiotic Earth is considered an essential step in the origin of life. Phosphorylation of ribose to form ribose 5′-phosphate with boric acid has been reported as a key step in ribonucleotide synthesis. However, the probability of phosphorylation of ribose with mineral phosphate, which is the most abundant form of phosphate on Earth, remains unclear. Carbonate and formate were both widely available compounds on prebiotic Earth and are known to increase the solubility of mineral phosphates. Therefore, the present study investigates the phosphorylation of ribose with apatite in the presence of carbonate or formate. Ribose was phosphorylated preferentially at 5′-hydroxyl when slightly alkaline ribose solution was dried down with hydroxyapatite, urea, boric acid, and formate or carbonate at 80 °C for 24 h. Conversely, the yield was limited to less than 10% in the absence of formate and carbonate at the same pH. Dissolution of apatite was substantially increased in the presence of carbonate and formate, allowing the phosphorylation of ribose. These results suggest that ribose 5′-phosphate may have been spontaneously formed in boron-rich evaporative environments on prebiotic earth, expanding the availability of ribonucleotides on prebiotic Earth in addition to the conventional process through ribonucleosides.