著者
Tadahisa Sugiura Chitaru Kurihara Masashi Kawabori Andre C. Critsinelis Andrew B. Civitello Jeffrey A. Morgan O. H. Frazier
出版者
The Editorial Committee of Annals of Thoracic and Cardiovascular Surgery
雑誌
Annals of Thoracic and Cardiovascular Surgery (ISSN:13411098)
巻号頁・発行日
vol.27, no.1, pp.64-67, 2021 (Released:2021-02-20)
参考文献数
5
被引用文献数
1 3

An increasing number of children with congenital heart disease are surviving into adulthood and subsequently developing end-stage heart failure. Two example populations are adults who have been previously operated on for congenitally corrected transposition of the great arteries (CCTGA) and transposition of the great arteries (TGA). Implantation of a continuous flow left ventricular assist device (CF-LVAD) in these patients can present unusual anatomical and physiologic challenges. In this report, we describe outcomes of CF-LVAD implantation in three such patients. These cases demonstrate the feasibility of implanting a CF-LVAD in patients who have undergone surgery for CCTGA and/or TGA.
著者
Yuki KOBAYASHI Nana INOUE Go SATO Takuya ITOU Hamilton P. SANTOS Cristina J. C. BRITO Albério A. B. GOMES Marli F. C. SANTOS Marlon V. SILVA Carla S. MOTA Fumio H. ITO Takeo SAKAI
出版者
JAPANESE SOCIETY OF VETERINARY SCIENCE
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
vol.69, no.7, pp.691-696, 2007 (Released:2007-08-05)
参考文献数
25
被引用文献数
13 15

The incidence of canine rabies has been widely reported in Brazil, and new rabies virus (RV) variants, genetically similar to canine RV, have recently been isolated from foxes. In order to derive the epidemiological characteristics of Brazilian Carnivora RV, Brazilian RVs isolated from dogs, cats, and foxes were genetically analyzed. Brazilian Carnivora RV isolates were divided into 2 main lineages. The predominant lineage was found in dogs and cats, which included the Argentinean and Bolivian Carnivora RV isolates, and was extensively distributed throughout Brazil and surrounding countries. The other lineage consisted of three sublineages containing Brazilian dog and fox RV isolates, with the dog sublineages located on an internal branch of 2 fox sublineages, suggesting that RV transmission events might have occurred between foxes and dogs in the past. These results suggest that contact between dogs and wildlife has the potential to generate new rabies variants and that it is important to control RV infection cycles in both dogs and wildlife to prevent spread of rabies infection.
著者
Jadson J. S. Oliveira Tiara S. Cabral Ruby Vargas-Isla José F. B. Silva Doriane P. Rodrigues Nelson Menolli Jr. Mariana P. Drewinski Noemia K. Ishikawa
出版者
The Mycological Society of Japan
雑誌
Mycoscience (ISSN:13403540)
巻号頁・発行日
vol.63, no.6, pp.254-266, 2022-09-20 (Released:2022-11-20)
参考文献数
51
被引用文献数
1

In the search for new strains of edible mushrooms in the Brazilian Amazon Forest, we found Lentinula specimens different from Lentinula raphanica. These were described morphologically and evaluated phylogenetically within the Lentinula clade. The mating system was determined, and interbreeding compatibility with L. raphanica was verified. The basidiomata have a cinnamon or deep orange to fulvous brown, moist to dry pileus, occasionally with whitish scales; crowded whitish cream lamellae; and an eccentric to lateral stipe. The typical, predominant basidiospores are 4.4-7.2 µm in length. Endogenous, elongate (7.8-14 µm) basidiospores were also found in some specimens. The long spores seem rare and occasional, but nonetheless a novelty for the group. Basidia are homogeneous in size, cheilocystidia are pyriform or bulboid, and caulocystidia are long and spheropedunculate. The hyphae of the pileipellis are pigment-encrusted. The characteristics match those of Agaricus ixodes originally described from Guyana, currently a synonym of Lentinula boryana. In the phylogenetic trees, such taxon appears distinct from L. boryana and sister to L. raphanica with strong support. This unique lineage was confirmed to be reproductively isolated from sympatric L. raphanica strains. Lentinula ixodes comb. nov. is the second species of the genus reported in the Amazon Forest.
著者
Akane Iida Kenji Nohara Fatimah Md. Yusoff Khwanruan Srinui Tran Manh Ha Susumu Ohtsuka Ephrime B. Metillo Honorio B. Pagliawan Jun Nishikawa
出版者
The Plankton Society of Japan, The Japanese Association of Benthology
雑誌
Plankton and Benthos Research (ISSN:18808247)
巻号頁・発行日
vol.16, no.4, pp.308-317, 2021-11-17 (Released:2021-11-18)
参考文献数
63

The rhizostome jellyfishes, Rhopilema hispidum and Lobonemoides robustus, are two of the most abundant and commercially important species in Southeast Asia. However, information on genetic diversity and continuities among local populations remains totally unknown. We explored the genetic structure and population continuities of R. hispidum and L. robustus using genetic markers (COI & ITS1 regions) at 11 locations in four countries in Southeast Asia where fisheries were conducted. Rhopilema populations showed genetic distances (ΦST) among locations correlated positively with geographic distances, suggesting that they are in the isolation-by-distance (IBD). In Lobonemoides, molecular analysis revealed three distinct clades corresponding to sampling locations. Genetic distances among locations in L. robustus suggested that all populations maintain significant isolation. Our study reveals that these two blooming species have different phylogeographic patterns and differ in genetic diversity and continuities. Eustatic sea level changes during the Pleistocene and present ocean current systems, as well as differences in biological characteristics of these two species may explain these phylogeographic differences. Our results also suggest that jellyfish fisheries need to be carefully managed to avoid extinction of local populations and maintain the genetic diversity of these species, especially for L. robustus, which exhibits considerable genetic diversity in each location.
著者
Manuela Malatesta Chiara Caporaloni Stefano Gavaudan Marco B.L. Rocchi Sonja Serafini Cinzia Tiberi Giancarlo Gazzanelli
出版者
Japan Society for Cell Biology
雑誌
Cell Structure and Function (ISSN:03867196)
巻号頁・発行日
vol.27, no.4, pp.173-180, 2002 (Released:2002-11-19)
参考文献数
29
被引用文献数
55 76

No direct evidence that genetically modified (GM) food may represent a possible danger for health has been reported so far; however, the scientific literature in this field is still quite poor. Therefore, we carried out an ultrastructural morphometrical and immunocytochemical study on hepatocytes from mice fed on GM soybean, in order to investigate eventual modifications of nuclear components of these cells involved in multiple metabolic pathways related to food processing. Our observations demonstrate significant modifications of some nuclear features in GM-fed mice. In particular, GM fed-mice show irregularly shaped nuclei, which generally represents an index of high metabolic rate, and a higher number of nuclear pores, suggestive of intense molecular trafficking. Moreover, the roundish nucleoli of control animals change in more irregular nucleoli with numerous small fibrillar centres and abundant dense fibrillar component in GM-fed mice, modifications typical of increased metabolic rate. Accordingly, nucleoplasmic (snRNPs and SC-35) and nucleolar (fibrillarin) splicing factors are more abundant in hepatocyte nuclei of GM-fed than in control mice. In conclusion, our data suggest that GM soybean intake can influence hepatocyte nuclear features in young and adult mice; however, the mechanisms responsible for such alterations remain unknown.
著者
Yamasaki Chisato Murakami Katsuhiko Fujii Yasuyuki Sato Yoshiharu Harada Erimi Takeda Jun-ichi Taniya Takayuki Satake Ryuichi Kikugawa Shingo Shimada Makoto Tanino Motohiko Halligan Brian Shimoyama Mary Twigger Simon Yura Kei Kimura Kouichi Yasuda Tomohiro Nishikawa Tetsuo Akiyama Yutaka Motono Chie Mukai Yuri Shionyu Masafumi Nagasaki Hideki Suwa Makiko Horton Paul Kikuno Reiko Ohara Osamu Lancet Doron Eveno Eric Graudens Esther Imbeaud Sandrine Debily Marie Anne Jia Libin Hayashizaki Yoshihide Amid Clara Han Michael Osanger Andreas Endo Toshinori Thomas Michael A. Hirakawa Mika Makalowski Wojciech Nakao Mitsuteru Kim Nam-Soon Thierry-Mieg Danielle Yoo Hyang-Sook De Souza Sandro J. Bonaldo Maria de Fatima Niimura Yoshihito Kuryshev Vladimir Schupp Ingo Wiemann Stefan Bellgard Matthew Thierry-Mieg Jean Wagner Lukas Zhang Qinghua Go Mitiko Minoshima Shinsei Ohtsubo Masafumi Hanada Kousuke Koyanagi Kanako O. Tonellato Peter Isogai Takao Zhang Ji Lenhard Boris Kim Sangsoo Chen Zhu Hinz Ursula Estreicher Anne Nakai Kenta Makalowska Izabela Barrero Roberto A. Hide Winston Tiffin Nicola Wilming Laurens Chakraborty Ranajit Soares Marcelo Bento Chiusano Maria Luisa Suzuki Yutaka Auffray Charles Yamaguchi-Kabata Yumi Itoh Takeshi Gough Craig Hishiki Teruyoshi Fukuchi Satoshi Nishikawa Ken Sugano Sumio Nomura Nobuo Tateno Yoshio Imanishi Tadashi Gojobori Takashi Chun Hong-Woo Habara Takuya Hanaoka Hideki Hayakawa Yosuke Hilton Philip B. Kaneko Yayoi Kanno Masako Kawahara Yoshihiro Kawamura Toshiyuki Matsuya Akihiro Nagata Naoki Nishikata Kensaku Ogura Noda Akiko Nurimoto Shin Saichi Naomi Sakai Hiroaki Sanbonmatsu Ryoko Shiba Rie Suzuki Mami Takabayashi Kazuhiko Takahashi Aiko Tamura Takuro Tanaka Masayuki Tanaka Susumu Todokoro Fusano Yamaguchi Kaori Yamamoto Naoyuki Okido Toshihisa Mashima Jun Hashizume Aki Jin Lihua Lee Kyung-Bum Lin Yi-Chueh Nozaki Asami Sakai Katsunaga Tada Masahito Miyazaki Satoru Makino Takashi Ohyanagi Hajime Osato Naoki Tanaka Nobuhiko Suzuki Yoshiyuki Ikeo Kazuho Saitou Naruya Sugawara Hideaki O'Donovan Claire Kulikova Tamara Whitfield Eleanor
出版者
Oxford University Press
雑誌
Nucleic Acids Research (ISSN:03051048)
巻号頁・発行日
vol.36, no.1, pp.D793-D799, 2008-01
被引用文献数
12

Here we report the new features and improvements in our latest release of the H-Invitational Database (H-InvDB; http://www.h-invitational.jp/), a comprehensive annotation resource for human genes and transcripts. H-InvDB, originally developed as an integrated database of the human transcriptome based on extensive annotation of large sets of full-length cDNA (FLcDNA) clones, now provides annotation for 120 558 human mRNAs extracted from the International Nucleotide Sequence Databases (INSD), in addition to 54 978 human FLcDNAs, in the latest release H-InvDB_4.6. We mapped those human transcripts onto the human genome sequences (NCBI build 36.1) and determined 34 699 human gene clusters, which could define 34 057 (98.1%) protein-coding and 642 (1.9%) non-protein-coding loci; 858 (2.5%) transcribed loci overlapped with predicted pseudogenes. For all these transcripts and genes, we provide comprehensive annotation including gene structures, gene functions, alternative splicing variants, functional non-protein-coding RNAs, functional domains, predicted sub cellular localizations, metabolic pathways, predictions of protein 3D structure, mapping of SNPs and microsatellite repeat motifs, co-localization with orphan diseases, gene expression profiles, orthologous genes, protein–protein interactions (PPI) and annotation for gene families. The current H-InvDB annotation resources consist of two main views: Transcript view and Locus view and eight sub-databases: the DiseaseInfo Viewer, H-ANGEL, the Clustering Viewer, G-integra, the TOPO Viewer, Evola, the PPI view and the Gene family/group.
著者
Keaten James A. Pribyl Charles B. 坂本 正裕
出版者
一般社団法人 日本認知・行動療法学会
雑誌
行動療法研究 (ISSN:09106529)
巻号頁・発行日
vol.26, no.1, pp.33-47, 2000-03-31 (Released:2019-04-06)

近年、日本の文部科学省はディベート、パブリック・スピーチ、口頭発表といったコミュニケーションを新たな学級活動として導入しようとしている。しかし、主に書くことによるコミュニケーションや評価に依存してきたシステムに、話すことを主としたコミュニケーションを導入する場合には、コミュニケーションへの恐れに関わる諸問題が生じてくる。これらの問題は、クラス内でのコミュニケーション活動が必ずしも話すことを主体とものではないことから隠蔽されてきた。それゆえ、いかに学生にコミュニケーションに対する恐れをうまく処理させるかについて、日本の教員や研究者が参考にすべき情報源は限定されてきたともいえる。本展望は、コミュニケーション不安・抑制・回避(CAIA)に言及しながら、コミュニケーションに対する恐れを緩和することに適用可能ないくつかの認知的および情動的技法を説明することで、その情報不足を補うことを目的としている。CAIAは対人抑制、行動混乱、コミュニケーション回避といったコミュニケーション障害を包括的に統一する用語であり、非生産的思考、条件反応、コンピテンス不足と関連づけられる。本稿では、口頭でのコミュニケーション障害に対する介入技法として(1)認知的再体制化、(2)視覚化、(3)メッセージ中心イメージ法、(4)系統的脱感作を解説している。紹介したテクニックはCAIAに悩む学生を援助するために用いるには未完成の介入技法かもしれない。各仲介技法の有効性と文化的な適切さの両者を試すにはさらなる研究が必要である。
著者
Maria Teresa B Abola Jonathan Golledge Tetsuro Miyata Seung-Woon Rha Bryan P Yan Timothy C Dy Marie Simonette V Ganzon Pankaj Kumar Handa Salim Harris Jiang Zhisheng Ramakrishna Pinjala Peter Ashley Robless Hiroyoshi Yokoi Elaine B Alajar April Ann Bermudez-delos Santos Elmer Jasper B Llanes Gay Marjorie Obrado-Nabablit Noemi S Pestaño Felix Eduardo Punzalan Bernadette Tumanan-Mendoza
出版者
Japan Atherosclerosis Society
雑誌
Journal of Atherosclerosis and Thrombosis (ISSN:13403478)
巻号頁・発行日
pp.53660, (Released:2020-07-04)
被引用文献数
49

Background: Peripheral artery disease (PAD) is the most underdiagnosed, underestimated and undertreated of the atherosclerotic vascular diseases despite its poor prognosis. There may be racial or contextual differences in the Asia-Pacific region as to epidemiology, availability of diagnostic and therapeutic modalities, and even patient treatment response. The Asian Pacific Society of Atherosclerosis and Vascular Diseases (APSAVD) thus coordinated the development of an Asia-Pacific Consensus Statement (APCS) on the Management of PAD. Objectives: The APSAVD aimed to accomplish the following: 1) determine the applicability of the 2016 AHA/ACC guidelines on the Management of Patients with Lower Extremity Peripheral Artery Disease to the Asia-Pacific region; 2) review Asia-Pacific literature; and 3) increase the awareness of PAD. Methodology: A Steering Committee was organized to oversee development of the APCS, appoint a Technical Working Group (TWG) and Consensus Panel (CP). The TWG appraised the relevance of the 2016 AHA/ACC PAD Guideline and proposed recommendations which were reviewed by the CP using a modified Delphi technique. Results: A total of 91 recommendations were generated covering history and physical examination, diagnosis, and treatment of PAD—3 new recommendations, 31 adaptations and 57 adopted statements. This Asia-Pacific Consensus Statement on the Management of PAD constitutes the first for the Asia-Pacific Region. It is intended for use by health practitioners involved in preventing, diagnosing and treating patients with PAD and ultimately the patients and their families themselves.
著者
丸山 茂徳 大森 聡一 千秋 博紀 河合 研志 B.F. WINDLEY
出版者
公益社団法人 東京地学協会
雑誌
地学雑誌 (ISSN:0022135X)
巻号頁・発行日
vol.120, no.1, pp.115-223, 2011-02-25 (Released:2011-05-20)
参考文献数
217
被引用文献数
26 42 22

Pacific-type orogeny (PTO) has long been recognized as a contrasting accretionary alternative to continent-continent collisional orogeny. However, since the original concept was proposed, there have many new developments, which make it timely to produce a new re-evaluated model, in which we emphasize the following new aspects. First, substantial growth of Tonarite–Trondhjemite–Granite (TTG) crust, and second the reductive effect of tectonic erosion. The modern analog of a Pacific-type orogen developed through six stages of growth exemplified by specific regions; initial stage 1: the southern end of the Andes; stage 2: exhumation to the mid-crustal level at Indonesia outer arc; stage 3: the Barrovian hydration stage at Kii Peninsula, SW Japan; stage 4: the initial stage of surface exposure of the high-P/T regional metamorphic belt at Olympic Peninsula, south of Seattle, USA; stage 5: exposure of the orogenic core at the surface at the Shimanto metamorphic belt, SW Japan; and stage 6: post-orogenic processes including tectonic erosion at the Mariana and Japan trench and the Nankai trough. The fundamental framework of a Pacific-type orogen is an accretionary complex, which includes limited ocean floor material, much terrigenous trench sediment, plus island arc, oceanic plateau, and intra-oceanic basaltic material from the ocean. The classic concept of a PTO stresses the importance of the addition within accreted rocks of new subduction-generated arcs and TTGs, which were added along the continental margins particularly during the Cretaceous. Besides the above additional or positive aspects of a PTO, here we emphasize the negative effects of previously little-considered tectonic erosion caused by subduction over time. The evaluation of such extensive tectonic erosion leads a prospect of the presence of huge quantities of TTG material in the lower transition zone, where many subducted slabs have ponded, as illustrated by mantle tomography. This is confirmed by density profiles of the mantle, which show that TTGs are abundant only along the bottom of the upper mantle accompanied by slab peridotite, lherzolite, and MORB. The major velocity anomaly in the lower transition zone is best explained by the predominance of SiO2 phases, hence TTG, and not by MORB or ultramafic rocks. Reasonable calculations indicate that at a depth range of 520-660 km TTG material amounts to 6-7 times more than the total mass of the surface continental crust. The traditional view is that the Japanese islands evolved since 520 Ma through five Pacific-type orogenies, which grew oceanward, thus creating a continuous accretionary complex ca. 400-500 km wide, with TTG growth at the continental side of each orogen. However, the subducting oceanic lithosphere has produced five times more TTG crust compared with the present TTG crust in the Japan islands. This is explained by the fact that over time tectonic erosion has dominated the increasing arc-TTG crust. Accordingly, Japan has lost four arc-TTG crusts to tectonic erosion. TTG material, such as trench sediment, arc crust, and continental margin crust, was fragmented by tectonic erosion and transported into the bottom of the upper mantle at depths of 520-660 km. Worldwide data suggest that tectonic erosion destroyed and fragmented most of the Pacific-type orogens.(View PDF for the rest of the abstract.)
著者
Paul K. B. ALANIS Yusuke YAMAYA Akihiro TAKEUCHI Yoichi SASAI Yoshihiro OKADA Toshiyasu NAGAO
出版者
The Japan Academy
雑誌
Proceedings of the Japan Academy, Series B (ISSN:03862208)
巻号頁・発行日
vol.89, no.8, pp.383-389, 2013-10-11 (Released:2013-10-11)
参考文献数
20
被引用文献数
8 15

Taal Volcano is one of the most active volcanoes in the Philippines. The magnetotelluric 3D forward analyses indicate the existence of a large high resistivity anomaly (∼100 Ω·m) with a volume of at least 3 km × 3 km × 3 km, which is capped by a conductive layer (∼10 Ω·m), beneath the Main Crater. This high resistivity anomaly is hypothesized to be a large hydrothermal reservoir, consisting of the aggregate of interconnected cracks in rigid and dense host rocks, which are filled with hydrothermal fluids coming from a magma batch below the reservoir. The hydrothermal fluids are considered partly in gas phase and liquid phase. The presence of such a large hydrothermal reservoir and the stagnant magma below may have influences on the volcano’s activity. Two possibilities are presented. First, the 30 January 1911 explosion event was a magmatic hydrothermal eruption rather than a base-surge associated with a phreato-magmatic eruption. Second, the earlier proposed four eruption series may be better interpreted by two cycles, each consisting of series of summit and flank eruptions.(Communicated by Seiya Uyeda, M.J.A.)
著者
Masahiro Yamada Eiji Hosoi Hidetoshi B. Tamate Junco Nagata Shirow Tatsuzawa Hiroyuki Tado Shinobu Ozawa
出版者
THE MAMMAL SOCIETY OF JAPAN
雑誌
Mammal Study (ISSN:13434152)
巻号頁・発行日
vol.31, no.1, pp.23-28, 2006 (Released:2006-07-08)
参考文献数
17
被引用文献数
22

Nucleotide sequences of sika deer (Cervus nippon) collected from the eastern part of Shikoku Island were investigated & compared with those from other areas. Nucleotide sequence of the whole D-loop region of the mitochondrial DNA was determined by direct sequencing technique for each sample. The phylogenetic tree constructed by the sequences indicates that sika deer from Shikoku Island are divided into two distinct lineages: the northern Japan group and the southern Japan group. Proportion of the northern Japan lineage was higher in the northeastern part of the sampling area. There was no border between the distribution of the two lineages, rather it seemed that their distribution intermingled. Besides, there were locations where both lineages were found within a small area. These results indicate that two lineages might be hybridized in some areas of eastern Shikoku.
著者
澤村 隆志 ベッドB.ビスタ 高田 豊雄
雑誌
研究報告コンピュータセキュリティ(CSEC)
巻号頁・発行日
vol.2012, no.11, pp.1-7, 2012-02-22

近年,マルウェア検知は,従来のパターンマッチング法の弱点を補うために,振る舞い検知を行うビヘイビア法の研究が盛んに行われている.これにより,未知のマルウェアに対しても対応することが可能である.しかし,これらの手法を利用しても 100% 検知可能ではなく,検知を免れる手法も考案されている.そこで,我々は,ビヘイビア法の補完として,従来のセキュリティツールを突破された後,ユーザの PC への被害から,マルウェアの存在を検知し,被害を最小限に抑えることが可能なのではないかと考えた.本稿では,数多くのマルウェアの中から,近年,被害が増加しているランサムウェアに注目し,このマルウェアが,PC 内に進入した後の挙動から,検知する手法を提案する.Recently, in order to cover a weak point of pattern matching method for malware detection, many researches have paid attention to behavior method. Though behavior method could be applicable to unknown malware, it cannot completely detect malwares. Additionaly, a number of techniques to evade behavior method are proposed and actually employed. We focus on actual behavior of malwares after evading conventional anti-virus software for supplementing conventional behavior method, in order to reduce actual damages by such malwares as small as possible. In this paper, specifically, we consider ransomware detection, whose damage are increasing considerably, by observing their activity after intruding PCs.