著者
TAKAHASHI Hiroshi G. DADO Julie Mae B.
出版者
Meteorological Society of Japan
雑誌
気象集誌. 第2輯 (ISSN:00261165)
巻号頁・発行日
pp.2018-031, (Released:2018-03-09)
被引用文献数
7

We offer a new perspective on a relationship between sea surface temperature (SST) over the windward region of the Philippines and rainfall in the western Philippines during the Asian summer monsoon season, which has been known as the negative correlation, using observational daily SST, rainfall, and atmospheric circulation datasets. This study focuses on the local SST effect rather than the remote effect. A warmer local SST results in greater rainfall over the western Philippines under similar monsoon westerlies conditions, particularly during moderate and relatively stronger monsoon regimes. This result is obtained after selecting only the moderate or relatively stronger monsoon days, because the positive effect of SST on rainfall is masked by the apparent negative correlation between SST and rainfall. The warmer SSTs being associated with less rainfall correspond to weaker cooling by weaker monsoon westerlies and the cooler SSTs being associated with more rainfall correspond to stronger cooling by stronger monsoon westerlies. The cooler SSTs are the result of stronger monsoon cooling and are not the cause of the greater rainfall, which is the apparent statistical relationship. This also implies that the monsoon westerly is the primary driver of the variation in rainfall in this region. We conclude that the local SST makes a positive contribution toward rainfall, although it does not primarily control rainfall. This conclusion can be applicable to coastal regions where, climatologically, rainfall is controlled by winds from the ocean.
著者
Ken Okumura Kazuo Matsumoto Yoshinori Kobayashi Akihiko Nogami Robert B Hokanson Fred Kueffer for the CRYO-Japan PMS Study Investigators
出版者
日本循環器学会
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
pp.CJ-16-0285, (Released:2016-06-30)
参考文献数
17
被引用文献数
2 31

Background:Outcomes of cryoballoon ablation for paroxysmal atrial fibrillation (PAF) have been reported in the Western countries but not in Japan. The CRYO-Japan PMS study was a single-arm, observational, multicenter, prospective study of the 2nd-generation cryoballoon Arctic Front AdvanceTM. We evaluated device- and procedure-related complications and clinical outcomes at 6 months.Methods and Results:The 616 patients (male, 72%; mean age, 63±11 years) were enrolled from 33 Japanese hospitals. Of all patients, 610 had PAF, and procedural data were analyzed in 607. A subset of 328 patients was followed for 6 months for the primary efficacy analysis. AF recurrence outside the 3-month blanking period or repeat ablation was considered treatment failure. Pulmonary vein isolation was achieved in 606/607 patients (99.8%); 1 patient (0.3%) had a repeat ablation during the blanking period. Freedom from AF at 6 months was 88.4% (95% CI: 84.1–91.6%). Device- and/or procedure-related adverse events included phrenic nerve injury unresolved at hospital discharge in 9/616 patients (1.5%), which resolved within 6 months in 7, pericardial effusion in 5/616 (0.8%), and tamponade in 4/616 (0.6%). One non-device-related death from pneumonia was reported 6 days post-procedure.Conclusions:Cryoballoon ablation is safe and effective for Japanese PAF patients, with 88.4% AF freedom at 6 months post-ablation.
著者
山崎 伸二 飯島 義雄 塚本 定三 塚本 定三 OUNDO Joseph O. NAIR Gopinath B. FARUQUE Shah M. RAMAMURTHY Thandavarayan
出版者
大阪府立大学
雑誌
基盤研究(B)
巻号頁・発行日
2007

インド、ケニアでの主要な下痢原因菌と考えられる下痢原性大腸菌とコレラ菌について解析した。下痢症患者便をマッコンキー寒天培地で培養し得られたコロニーからボイルテンプレートを作製しReal-time PCRで下痢原性大腸菌の病原因子を網羅的に解析した。インドでは、ipaH遺伝子陽性菌(腸管組織侵入性大腸菌)が最も陽性率が高く、次にeaeA遺伝子陽性菌(腸管病原性大腸菌)の順であったが、ケニアではelt遺伝子陽性菌(腸管毒素原生大腸菌)の陽性率が最も高く、次にaagR遺伝子陽性菌(腸管凝集性大腸菌)であった。我が国で陽性率の高いcdt遺伝子陽性大腸菌がインドやケニアではあまり検出されなかった。一方、コレラ菌に関しては、バングラデシュで見つかったハイブリッド型O1コレラ菌(エルトールバリアント)はインドでは1990年に既に分離されており1995年以降分離されたO1コレラ菌は全てハイブリッド型(エルトールバリアント)であることが明らかとなった。ケニアでのコレラの流行で分離されたコレラ菌もエルトールバリアントであり、エルトールバリアントがアフリカ、ケニアでも広く流行に関わっていることが明らかとなった。
著者
Özge TURNA YILMAZ TSF TOYDEMIR İ KIRŞAN B DOKUZEYLUL Z GUNAY E KARACAM
出版者
公益社団法人 日本獣医学会
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
pp.14-0112, (Released:2014-09-20)
被引用文献数
5

The analgesic effect of wound infiltration with bupivacaine was evaluated in cats undergoing bilateral mastectomy. Twenty-one female cats with mammary gland tumors were anesthetized with propofol and oxygen-isoflurane anesthesia following premedication with atropine. In the trial group (Group I; n=11), 30 ml of saline containing 2 mg/kg of bupivacaine was infiltrated topically into the surgical wound right after removal of the mammary glands, whereas only saline solution was infiltrated in the control group (Group II; n=10). At the same time, carprofen (4 mg/kg) was also administered subcutaneously in both groups. Behavioral signs of pain were monitored during the recovery period after general anaesthesia. In order to examine the behavioral changes associated with acute pain, a questionnaire was prepared and given to the owners to be completed 4 hr and then 10 hr after the operation. According to the owners’ anwers to the questionnaire, a pain score was specified using a “numerical rating scale” for each cat. Although some cats showed mild to moderate pain, the pain score recorded at 4 hr after the operation was significantly lower in Group I (P<0.001). No significant difference was found at 10 hr after the operation between the groups. The incidence of vocalization, aggression and convulsion within 2 hr after the operation were also lower in Group I. In conclusion, wound infiltration with bupivacaine before incisional closure provided reliable analgesia at least 4 hr after bilateral radical mastectomy in cats.
著者
Masahiro Yamada Eiji Hosoi Junco Nagata Hidetoshi B. Tamate Hiroyuki Tado
出版者
日本哺乳類学会
雑誌
Mammal Study (ISSN:13434152)
巻号頁・発行日
vol.32, no.3, pp.121-127, 2007 (Released:2007-10-10)
参考文献数
22
被引用文献数
13 2

Samples of the sika deer (Cervus nippon) were collected from Kyushu and Shikoku Islands of Japan and surrounding areas, and their nucleotide sequences were analyzed. Sequences of the whole control region of the mitochondrial DNA were determined and phylogenetic trees were constructed using the neighbor-joining method and the maximum likelihood method. We also investigated gene genealogies for the sequences using the statistical parsimony network approach. Phylogenetic trees showed that only the Yakushima/Tanegashima populations were genetically distant from other populations. The statistical parsimony network, however, indicated a close relationship of the Miyazaki populations to some of the Shikoku populations. It was suggested that Shikoku Island played an important role in the divergence from the southern Japan lineage of C. nippon.
著者
Kent R. Walters Jr. S. Indu Rupassara R.J. Cody Markelz Andrew D.B. Leakey William M. Muir Barry R. Pittendrigh
出版者
日本毒性学会
雑誌
The Journal of Toxicological Sciences (ISSN:03881350)
巻号頁・発行日
vol.37, no.4, pp.773-790, 2012-08-01 (Released:2012-08-01)
参考文献数
55
被引用文献数
1 9 1

Methamphetamine (MA) appears to produce neurotoxic effects, in part, through disruptions of energy metabolism. A recent study of the whole-body proteome of Drosophila melanogaster showed many changes in energy metabolism-related proteins, leading us to hypothesize that MA toxicity may cause whole-body disruptions of energy metabolism. To test this, we monitored the response of energy reserves and other metabolites to MA-exposure with and without the addition of dietary glucose. We also monitored changes in feeding behavior, locomotor activity and respiration rates associated with MA-exposure to investigate how MA affects energy balance. We observed that glycogen and triglyceride levels decreased dramatically within 48 hr of MA-exposure, indicating a strongly negative caloric balance. Behavioral assays revealed that MA-treated flies decreased food consumption by 60-80% and exhibited a 2-fold increase in locomotion. Caloric expenditure decreased with MA-exposure, apparently due to a compensatory decrease in resting metabolism, showing that anorexia was the primary driver of the negative caloric balance. Additionally, we observed that glucose supplementation of MA-containing diet increased glycogen reserves by 44% at 48 hr, leading to a commensurate increase in survivorship. We conclude that dietary sugar supplementation enhances survivorship by partially compensating for decreased caloric intake resulting from MA-induced anorexia. The observation that MA produces similar behavioral changes in Drosophila and humans, i.e. increased locomotor activity and anorexia, further supports the use of Drosophila as a model organism for the study of the effects of MA.
著者
Erik S. WALLEN Karen B. MULLOY
出版者
独立行政法人 労働安全衛生総合研究所
雑誌
Industrial Health (ISSN:00198366)
巻号頁・発行日
vol.44, no.4, pp.661-664, 2006 (Released:2006-11-02)
参考文献数
15
被引用文献数
3 3 8

Occupational diseases are a significant problem affecting public health. Safety training is an important method of preventing occupational illness. Training is increasingly being delivered by computer although theories of learning from computer-based multimedia have been tested almost entirely on college students. This study was designed to determine whether these theories might also be applied to safety training applications for working adults. Participants viewed either computer-based multimedia respirator use training with concurrent narration, narration prior to the animation, or unrelated safety training. Participants then took a five-item transfer test which measured their ability to use their knowledge in new and creative ways. Participants who viewed the computer-based multimedia trainings both did significantly better than the control group on the transfer test. The results of this pilot study suggest that design guidelines developed for younger learners may be effective for training workers in occupational safety and health although more investigation is needed.
著者
The Working Group for Renaming Diabetes Insipidus Hiroshi Arima Timothy Cheetham Mirjam Christ-Crain Deborah Cooper Mark Gurnell Juliana B Drummond Miles Levy Ann I McCormack Joseph Verbalis John Newell-Price John A H Wass
出版者
The Japan Endocrine Society
雑誌
Endocrine Journal (ISSN:09188959)
巻号頁・発行日
vol.69, no.11, pp.1281-1284, 2022 (Released:2022-11-28)
参考文献数
10
被引用文献数
1 5

“What’s in a name? That which we call a rose/By any other name would smell as sweet.” (Juliet, from Romeo and Juliet by William Shakespeare). Shakespeare’s implication is that a name is nothing but a word and it therefore represents a convention with no intrinsic meaning. Whilst this may be relevant to romantic literature, disease names do have real meanings, and consequences, in medicine. Hence, there must be a very good rational for changing the name of a disease that has a centuries-old historical context. A working group of representatives from national and international endocrinology and pediatric endocrine societies now proposes changing the name of “diabetes insipidus” to “Arginine Vasopressin Deficiency (AVP-D)” for central etiologies, and “Arginine Vasopressin Resistance (AVP-R)” for nephrogenic etiologies. This editorial provides both the historical context and the rational for this proposed name change.
著者
Silvano Gallus Alessandra Lugo Chiara Stival Sonia Cerrai Luke Clancy Filippos T. Filippidis Giuseppe Gorini Maria José Lopez Ángel López-Nicolás Sabrina Molinaro Anna Odone Joan B. Soriano Olena Tigova Piet A. van den Brandt Constantine I. Vardavas Esteve Fernandez the TackSHS Project Investigators
出版者
Japan Epidemiological Association
雑誌
Journal of Epidemiology (ISSN:09175040)
巻号頁・発行日
vol.33, no.6, pp.276-284, 2023-06-05 (Released:2023-06-05)
参考文献数
44
被引用文献数
3

Background: Limited data on electronic cigarette prevalence, patterns, and settings of use are available from several European countries.Methods: Within the TackSHS project, a face-to-face survey was conducted in 2017–2018 in 12 European countries (Bulgaria, England, France, Germany, Greece, Ireland, Italy, Latvia, Poland, Portugal, Romania and Spain). Overall, 11,876 participants, representative of the population aged ⩾15 years in each country, provided information on electronic cigarette.Results: 2.4% (95% confidence interval [CI], 2.2–2.7%) of the subjects (2.5% among men and 2.4% among women; 0.4% among never, 4.4% among current- and 6.5% among ex-smokers) reported current use of electronic cigarette, ranging from 0.6% in Spain to 7.2% in England. Of the 272 electronic cigarette users, 52.6% were dual users (ie, users of both electronic and conventional cigarettes) and 58.8% used liquids with nicotine. In all, 65.1% reported using electronic cigarette in at least one indoor setting where smoking is forbidden; in particular, at workplaces (34.9%) and bars and restaurants (41.5%). Multivariable logistic regression analysis showed that electronic cigarette use was lower among older individuals (P for trend <0.001) and higher among individuals with high level of education (P for trend = 0.040). Participants from countries with higher tobacco cigarette prices more frequently reported electronic cigarette use (odds ratio 3.62; 95% CI, 1.80–7.30).Conclusion: Considering the whole adult population of these 12 European countries, more than 8.3 million people use electronic cigarettes. The majority of users also smoked conventional cigarettes, used electronic cigarettes with nicotine, and consumed electronic cigarettes in smoke-free indoor areas.
著者
Amy K. PARKIN Amy J. ZADOW Rachael E. POTTER Ali AFSHARIAN Maureen F. DOLLARD Silvia PIGNATA Arnold B. BAKKER Kurt LUSHINGTON
出版者
National Institute of Occupational Safety and Health
雑誌
Industrial Health (ISSN:00198366)
巻号頁・発行日
pp.2022-0078, (Released:2022-08-08)
被引用文献数
4

Due to the COVID-19 pandemic, the number of employees in flexible work from home has increased markedly along with a reliance on information communication technologies. This study investigated the role of an organisational factor, psychosocial safety climate (PSC; the climate for worker psychological health and safety), as an antecedent of these new kinds of demands (specifically work from home digital job demands) and their effect on work-life conflict. Data were gathered via an online survey of 2,191 employees from 37 Australian universities. Multilevel modelling showed that university level PSC to demands, y=−0.09, SE=0.03, p<0.01, and demands to work-life conflict, y=0.51, SE=0.19, p<0.05, relationships were significant. Supporting the antecedent theory, university level PSC was significantly indirectly related to work-life conflict via demands (LL −0.10 UL −0.01). Against expectations PSC did not moderate the demand to work-life conflict relationship. The results imply that targeting PSC could help prevent work from home digital job demands, and therefore, work-life conflict. Further research is needed on the role of digital job resources as flexible and hybrid work takes hold post COVID.
著者
B. A. Fenderson 山形 達也
出版者
FCCA(Forum: Carbohydrates Coming of Age)
雑誌
Trends in Glycoscience and Glycotechnology (ISSN:09157352)
巻号頁・発行日
vol.5, no.24, pp.271-285, 1993-07-02 (Released:2010-01-05)
参考文献数
76
被引用文献数
3 5

着床とは哺乳動物の初期胚が子宮壁に接着する発生上の複雑な過程である。ステロイドホルモンおよびサイトカインの影響下で非接着性の子宮上皮が接着性に変わることが重要である。子宮壁の接着性が変わる間に、子宮上皮の糖脂質や糖タンパク組成の変化、上皮表面の複合糖質分子の大きさや荷電の変化、内腔液に分泌される糖タンパク質のパターンの変化などを含む糖鎖の変化が沢山見られる。胚でも着床に先立って糖抗原の発現が大きく変わる。これらの発生特異的な変化が胚盤胞の子宮への接着の時間や場所を調節しているのかも知れない。着床に伴う糖鎖の役割について幾つかの検証しうる仮説が出されていて、糖鎖-タンパク質相互作用と、糖鎖-糖鎖間相互作用のどちらも有力である。
著者
Kent L. GEE Eric B. WHITING Tracianne B. NEILSEN Michael M. JAMES Alexandria R. SALTON
出版者
THE JAPAN SOCIETY FOR AERONAUTICAL AND SPACE SCIENCES
雑誌
TRANSACTIONS OF THE JAPAN SOCIETY FOR AERONAUTICAL AND SPACE SCIENCES, AEROSPACE TECHNOLOGY JAPAN (ISSN:18840485)
巻号頁・発行日
vol.14, no.ists30, pp.Po_2_9-Po_2_15, 2016 (Released:2016-07-27)
被引用文献数
5 5

Near-field characterization of the acoustical environment near rockets has often involved extrapolating far-field measurements. However, because far-field amplitude data reveals only limited information about source characteristics, a vector intensity measurement system and analysis package has been developed to examine source features more directly. This paper describes the development of the measurement and analysis capability and its application to a horizontal firing of a GEM-60 solid propellant rocket motor firing conducted at ATK Space Systems near Promontory, Utah. An analysis of near-field intensity data provides insight both into the spatial extent and principal radiation lobe as a function of frequency. For 50 Hz, the far-field spectral peak frequency in the maximum radiation direction, the dominant source region derived from tracing the near-field intensity vectors spans 17-32 nozzle diameters, with peak radiation at ~68°. At high frequencies, the radiation results from a more contracted region that occurs farther upstream and is directed at about ~85°. These results point to the potential utility of near-field vector intensity measurements, in part because the near-field environments represented do not agree with historical far-field data-based models.