著者

柏原 建一

出版者

日本神経治療学会

雑誌

神経治療学 (ISSN:09168443)

巻号頁・発行日

vol.33, no.3, pp.313-317, 2016 (Released:2016-11-10)

参考文献数

8

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Parkinson's disease (PD) is a progressive disorder of the nervous system that affects motor, neuropsychiatric, sleep, autonomic, and sensory functions. Motor symptoms of PD may include tremor, bradykinesia, muscle rigidity, postural instability, and speech and swallowing disturbances. Neuropsychiatric symptoms include depression, apathy, anxiety, cognitive impairment, hallucinations, and delusions. Sleep problems include insomnia, REM sleep behavioral disorder, excessive daytime sleepiness and sudden onset of sleep. Main autonomic symptoms include constipation, urinary dysfunction, orthostatic hypotension, sexual dysfunction, drenching sweat. Anosmia and sensory symptoms also are frequent complications of PD. Diagnosis of PD is determined by detecting these symptoms. The essential criterion is parkinsonism, which is defined as bradykinesia, in combination with at least 1 of rest tremor or rigidity. In addition, diagnosis of clinically established PD requires absence of absolute exclusion criteria, at least two supportive criteria, and no red flags. Exclusion criteria includes cerebellar abnormalities, downward vertical supranuclear gaze palsy, frontotemporal dementia, parkinsonism restricted to the lower limbs, treatment with dopamine receptor blocker, etc. Drugs, deep brain stimulation (DBS), and rehabilitation are measures to manage PD. Levodopa and dopamine agonists are the cardinal drugs to treat motor symptoms. Levodopa tended to induce motor complications such as wearing off and dyskinesia if used in the larger amount of more than 400 mg/day to PD patients with younger onset. Dopamine agonists induce motor complication less frequently than levodopa, but may include hallucinations, daytime sleepiness and impulse control disorders such as hypersexuality, gambling, and eating. Apomorphine is used for quick relief. DBS is a surgical procedure to treat motor symptoms of PD. Nowadays, increasing evidences support that physical activity improve motor and non-motor symptoms of PD. Global Parkinson's disease survey steering committee concluded in 2002 that “satisfaction with the explanation of the condition at diagnosis” and “current feelings of optimism” have a significant impact on health-related quality of life of PD patients.

著者

武田仰天子 著

出版者

春陽堂

巻号頁・発行日

1893

著者

小川 道子 上田 敏彦 大久保 滉 森井 外吉

出版者

関西医科大学医学会

雑誌

関西医科大学雑誌 (ISSN:00228400)

巻号頁・発行日

vol.28, no.3, pp.544-555, 1976-09-20 (Released:2013-02-19)

参考文献数

27

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Reported: This autopsy case of myasthenia gravis in a 41 year old female revealed thymus hyperplasia with germinal centers remaining in the fatty tissues. The infiltration of lymphocytes (lymphorrhage) was remarkable only in the tissues near the thymus, namely the intercostal muscles, myocardium, and thyroid; in the other affected skeletal muscles, it was only slight. The Lymphorrhage in the myocardium was so remarkable that was histologically diagnosed as subacute myocarditis.Discussed: In agreement with recent studies, these findings seem to suggest the view that myasthenia gravis is an autoimmune disease.

著者

乾 弘幸 村上 恭一

出版者

九州産業大学産業経営研究所

雑誌

産業経営研究所報

巻号頁・発行日

no.34, pp.1-17, 2002-03

著者

青山学院大学日本文学会 [編集]

出版者

青山学院大学日本文学会

巻号頁・発行日

1970

著者

木原 信市 岩坪 聖子 大塚 裕一

出版者

一般社団法人 日本看護研究学会

雑誌

日本看護研究学会雑誌 (ISSN:21883599)

巻号頁・発行日

vol.14, no.3, pp.3_7-3_16, 1991-07-01 (Released:2016-03-31)

参考文献数

30

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胸腺摘出術を受けた9名のMG患者の日常生活における問題点とその工夫について研究をおこなった。その要約は以下の通りである。(1) 胸腺摘出術を受けたMG患者の治療効果は,病期(Osserman分類),年齢,病悩期間などの条件により症状の改善および寛解に差があった。 (2) MGの症状が改善または寛解していない患者は,主に咀嚼・嚥下障害,上肢筋麻痺・挙上困難,下肢筋麻痺,眼障害などのため日常生活において不便さを感じていた。しかし,これらの不便さに対しては患者自身で考慮した工夫がなされていた。 (3) MG患者の心理的状況として,術前は開胸術や手術の結果に対する不安が多く,一方術後では病悩期間が長く手術の効果が少ない症例において生きていくことへの不安感が強かった。

著者

新谷 雅司 安永 幸二郎

出版者

関西医科大学医学会

雑誌

関西医科大学雑誌 (ISSN:00228400)

巻号頁・発行日

vol.41, no.1, pp.1-2, 1989-03-20 (Released:2013-02-19)

参考文献数

4

著者

遠藤元閑 編

出版者

吉文字屋市兵衛

巻号頁・発行日

vol.[5],

著者

西村 沙矢香 宮林 沙季 瀧井 幸男

出版者

日本食生活学会

雑誌

日本食生活学会誌 (ISSN:13469770)

巻号頁・発行日

vol.21, no.3, pp.217-221, 2010-12-30 (Released:2011-01-24)

参考文献数

17

被引用文献数

1 1

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This research studied the eating behavior and genetic factors that cause masked obesity, in which body fat percentage is high even though the body weight is low or normal, a phenomenon that is increasing among young Japanese women. This study performed physical measurement, an eating-behavior survey based on EAT-26, and a genetic polymorphism test that used the non-invasive collection of fingernail clippings on 94 young women. The result showed that 13. 8% of the women have masked obesity, while 39. 4% have masked obesity tendency, and the total of both groups equaled more than half the total number (53. 2%). When the masked obesity group is compared to the standard group, no difference can be seen in the frequency of appearance of β3-adrenergic receptor (β3AR) genetic polymorphism (Trp64Arg) and insulin-induced gene 2 (INSIG2) genetic polymorphism (rs7566605), but there is a significantly higher rating in EAT-26. These results suggest the possibility that unique eating behavior habits of young women are largely involved in causing masked obesity in this population.

著者

豊国

雑誌

俳優似顔東錦絵

著者

松下見林

巻号頁・発行日

vol.[1], 1665

著者

永代 行日出 細谷 浩之 中野 貴裕

出版者

一般社団法人 日本機械学会

雑誌

日本機械学会論文集 (ISSN:21879761)

巻号頁・発行日

vol.83, no.855, pp.17-00310-17-00310, 2017 (Released:2017-11-25)

参考文献数

23

被引用文献数

1

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Acoustic metamaterial can have arbitrary acoustic characteristics , and there is possibility to improve acoustic performance of any products dramatically. As metamaterial, many kind of types have been propounded and studied. It is mainly classified into resonance type and non-resonance type.Resonance type metamaterial can change acousic characteristics drastically, but frequency range is narrow. Non-resonance type’s acoustic characteristics range is less than resonance type, but it can be changed in broad frequency band. It is a great advantage to use. About non-resonance type metamaterial, it has been already studied to control transmitted sound, but it has not been studied about reflection sound. If reflection sound control become possible, effective method can be chosen to solve noise problem. For example, resonance frequency in a duct will be shifted by changing reflection direction from the wall. In this study, the design method of non-resonance type metamaterial to control reflection sound has been studied by using FEM and Transfer-function method, and to verify the design method, element test was conducted. Element test result correspond well with analysis result, and the design method of acoustic metamaterial has been verified in this study. In order to put into practical use, further study with actual product shape is needed to confirm manufacturability.

著者

万亭応賀//作 一陽斎豊国//画

出版者

若狭屋与市

雑誌

双六

巻号頁・発行日

1843

著者

中里介山 原作

出版者

黎明社

巻号頁・発行日

vol.宇津木兵馬の巻, 1955

著者

中里介山 原作

出版者

黎明社

巻号頁・発行日

vol.机竜之助の巻, 1955

著者

清水 由美子

出版者

中央大学文学部

雑誌

中央大学文学部紀要 = Journal of the Faculty of Literature, Chuo University (ISSN:05296803)

巻号頁・発行日

no.264, pp.69-88, 2017-03

出版者

写

巻号頁・発行日

1827

出版者

[s.n.]

巻号頁・発行日

0000

著者

中野 敬一 Keiichi NAKANO

出版者

神戸女学院大学女性学インスティチュート

雑誌

女性学評論 = Women's studies forum (ISSN:09136630)

巻号頁・発行日

no.31, pp.227-249, 2017-03

著者

長谷川 隆

出版者

お茶の水音楽研究会

雑誌

お茶の水音楽論集 (ISSN:1344672X)

巻号頁・発行日

no.13, pp.36-46, 2011-04