著者
松室隆光 著
出版者
啓文社
巻号頁・発行日
1937
著者
内田 豊
出版者
東京大学理学部
雑誌
東京大学理学部廣報
巻号頁・発行日
vol.20, no.3, pp.9-12, 1988-12
著者
有馬 朗人
出版者
東京大学理学部
雑誌
東京大学理学部廣報
巻号頁・発行日
vol.19, no.2, pp.4-5, 1987-09
著者
Ken-ichi Shimose Shingo Shimizu Takeshi Maesaka Ryohei Kato Kaori Kieda Koyuru Iwanami
出版者
(公社)日本気象学会
雑誌
SOLA (ISSN:13496476)
巻号頁・発行日
vol.12, pp.215-219, 2016 (Released:2016-08-05)
参考文献数
28
被引用文献数
4

This study investigated the impact of observation operators on low-level wind speed analysis. An evaluation of wind speeds retrieved by variational multiple-Doppler analyses using radial velocities (Vr) based on the formats of both a Plan Position Indicator (PPI) (hereafter, PPI-VAR) and a Constant Altitude Plan Position Indicator (CAPPI) (hereafter, CAPPI-VAR) was performed for comparison with wind speeds observed by a wind profiler during the warm season of three consecutive years. The statistical analysis showed that PPI-VAR was more accurate than CAPPI-VAR at 500 m above ground level (AGL). The error of CAPPI-VAR at 500 m AGL was caused by a representative error of CAPPI-formatted Vr derived from a certain radar whose beam height was far from the analysis level, and this error became more obvious the greater the vertical difference in wind speed across the analysis level. CAPPI-VAR uses CAPPI-formatted Vr from each radar equally; thus, the representative error might cause performance degradation of CAPPI-VAR at 500 m AGL. Conversely, PPI-VAR uses PPI-formatted Vr from each radar with appropriate weighting based on the beam height distance from the analysis level. PPI-VAR showed better results at 500 m AGL because the observation grid points were dense around 500 m AGL.
著者
井上 啓子 清水 和栄 平賀 恵子 吉川 妙子 梅村 聡美 大瀧 香織 高橋 恵理香 徳永 千賀 古田 久美子 若山 真規子 水野 晴代 松村 香里 高井 千佳 加藤 静香 宇野 千晴 出口 香菜子 榊原 知世 高橋 宏 伊藤 恭彦
出版者
一般社団法人 日本透析医学会
雑誌
日本透析医学会雑誌 (ISSN:13403451)
巻号頁・発行日
vol.49, no.7, pp.493-501, 2016 (Released:2016-07-28)
参考文献数
20

維持血液透析患者のprotein-energy wasting (PEW) の実態とPEWとの関連因子を検討した. 透析導入後6か月以上409例の合併症, 身体計測値, 血液検査, 食事摂取量を調査. 国際腎疾患栄養代謝学会による区分に従いPEWを判定し, Logistic回帰分析により関連因子を求めた. 年齢64±11歳, 透析歴8 (3~14) 年, 高血圧合併74.3%, BMI 21.1±3.4kg/m2, 血清Alb 3.7±0.3g/dL, エネルギー30±6kcal/kg IBW, たんぱく質1.01±0.22g/kg IBWであった. PEWは3項目以上該当17.1%, 年齢, 透析歴, 高血圧がPEWとの独立した背景因子であった. 食品群別摂取量との関連は, 肉類, 魚介類, 砂糖類摂取量が独立因子となった. さらにROC解析によるカットオフ値 (肉類46.7g, 魚介類41.7g, 砂糖類9.0g) 未満の摂取のオッズ比は肉類2.74 (95%CI 1.55-4.85, p=0.001), 魚介類2.04 (95%CI 1.16-3.61, p=0.014), 砂糖類1.88 (95%CI 1.05-3.37, p=0.033) であった. 通院患者の17.1%がPEWであり, 肉類, 魚介類, 砂糖類の摂取不足とPEW発症との関連が示唆された.
著者
Tatsuo Shimura Masahiko Shibata Kenji Gonda Takahiro Nakajima Shun Chida Masaru Noda Satoshi Suzuki Izumi Nakamura Keiichi Nakano Toshihiko Fukushima Shinichi Suzuki Seiichi Takenoshita
出版者
日本癌病態治療研究会
雑誌
Annals of Cancer Research and Therapy (ISSN:13446835)
巻号頁・発行日
vol.24, no.1, pp.35-40, 2016-01-13 (Released:2016-03-31)
参考文献数
40
被引用文献数
2

Background and Aims: Several investigators have reported the significance of circulating galectin-3 in thyroid cancer patients. However, the precise meaning of circulating galectin-3 remains unclear. The aim of this study was to investigate the relationships between serum galectin-3 levels and angiogenetic factors, and nutritional and inflammatory indicators in patients with thyroid cancer. Materials and Methods: Sixty-one patients with thyroid tumors were enrolled, comprising 47 pre-treatment thyroid cancer patients and 14 patients with benign thyroid diseases. Galectin-3, interleukin (IL)-6, vascular endothelial growth factor, granulocyte colony-stimulating factor (G-CSF), soluble form of intercellular adhesion molecule-1 (sICAM-1), retinol binding protein, prealbumin, albumin, and transferrin were measured. C-reactive protein (CRP), neutrophil count, lymphocyte count, and neutrophil/lymphocyte ratio (NLR) were also investigated. Results: The amounts of circulating galectin-3 in benign disease and thyroid cancer were significantly higher than those of healthy volunteers (P < 0.001). Analysis of galectin-3 performance in distinguishing malignant disease from benign disease using a receiver operating characteristic curve revealed that the area under the curve was 0.555. There were statistically significant correlations between the circulating amount of galectin-3 and IL6, G-CSF, and sICAM-1. Serum galectin-3 showed statistically significant correlations with albumin, prealbumin, and transferrin. Circulating galectin-3 exhibited strong correlations with CRP, neutrophil count, lymphocyte count, and NLR. Conclusions: Galectin-3 may be one of the key factors in the regulation of angiogenesis, inflammation, and nutrition.
著者
Nobuyuki Uchikoga Yuri Matsuzaki Masahito Ohue Yutaka Akiyama
出版者
一般社団法人 日本生物物理学会
雑誌
Biophysics and Physicobiology (ISSN:21894779)
巻号頁・発行日
vol.13, pp.105-115, 2016 (Released:2016-07-14)
参考文献数
31
被引用文献数
7

Analysis of protein-protein interaction networks has revealed the presence of proteins with multiple inter­action ligand proteins, such as hub proteins. For such proteins, multiple ligands would be predicted as interacting partners when predicting all-to-all protein-protein interactions (PPIs). In this work, to obtain a better understanding of PPI mechanisms, we focused on protein interaction surfaces, which differ between protein pairs. We then performed rigid-body docking to obtain information of interfaces of a set of decoy structures, which include many possible interaction surfaces between a certain protein pair. Then, we investigated the specificity of sets of decoy interactions between true binding partners in each case of alpha-chymotrypsin, actin, and cyclin-dependent kinase 2 as test proteins having mul­tiple true binding partners. To observe differences in interaction surfaces of docking decoys, we introduced broad interaction profiles (BIPs), generated by assembling interaction profiles of decoys for each protein pair. After cluster analysis, the specificity of BIPs of true binding partners was observed for each receptor. We used two types of BIPs: those involved in amino acid sequences (BIP-seqs) and those involved in the compositions of interacting amino acid residue pairs (BIP-AAs). The specificity of a BIP was defined as the number of group members including all true binding partners. We found that BIP-AA cases were more specific than BIP-seq cases. These results indicated that the composition of inter­acting amino acid residue pairs was sufficient for determining the properties of protein interaction surfaces.