著者

Minhaz KAMAL Chowdhury Mohammad ABDULLAH Fairuz SHAIARA Abu Raihan Mostofa KAMAL Md Mehedi HASAN Jik-Soo KIM Md Azam HOSSAIN

出版者

The Institute of Electronics, Information and Communication Engineers

雑誌

IEICE Transactions on Information and Systems (ISSN:09168532)

巻号頁・発行日

vol.E106.D, no.5, pp.1085-1088, 2023-05-01 (Released:2023-05-01)

参考文献数

6

被引用文献数

1

---

The literature presents a digitized pension system based on a consortium blockchain, with the aim of overcoming existing pension system challenges such as multiparty collaboration, manual intervention, high turnaround time, cost transparency, auditability, etc. In addition, the adoption of hyperledger fabric and the introduction of smart contracts aim to transform multi-organizational workflow into a synchronized, automated, modular, and error-free procedure.

著者

Wenqi DENG Jun-ichiro JO Hidetoshi MORIKUNI Satoshi SASAYAMA Yoshiya HASHIMOTO Naoyuki MATSUMOTO Yoshitomo HONDA

出版者

The Japanese Society for Dental Materials and Devices

雑誌

Dental Materials Journal (ISSN:02874547)

巻号頁・発行日

vol.42, no.3, pp.351-359, 2023-05-25 (Released:2023-05-30)

参考文献数

52

---

Senescence-associated secretory phenotype (SASPs) secreted from senescent cells often cause the deleterious damages to the surrounding tissues. Although dedifferentiated fat (DFAT) cells prepared are considered a promising cell source for regenerative therapies, SASPs from DFAT cells undergoing long-term cell culture, which latently induce replicative senescence, have barely been explored. The present study was designed to investigate senescent behaviors in rat-derived DFAT cells at high passage numbers and to analyze the possible types of SASPs. Our data show that DFAT cells undergo senescence during replicative passaging, as determined by multiple senescent hallmarks including morphological changes in cell shape and nucleus. Moreover, RT2 PCR array analysis indicated that senescent DFAT cells expressed higher levels of 16 inflammatory cytokines (Ccl11, Ccl12, Ccl21, Ccl5, Csf2, Cxcl1, Cxcl12, Ifna2, IL11, IL12a, IL13, IL1a, IL1rn, IL6, Mif, and Tnf) associated with SASPs than non-senescent cells. This study implicates that rat DFAT cells undergo cellular senescence after long-term cell culture; cautious consideration should be paid to treat SASP secretion when senescent DFAT cells are used in regenerative medicine.

著者

Atsushi TOMINAGA V. Benno MEYER-ROCHOW Taku OKAMOTO Takeo KURIYAMA Kanto NISHIKAWA Masafumi MATSUI

出版者

The Herpetological Society of Japan

雑誌

Current Herpetology (ISSN:13455834)

巻号頁・発行日

vol.35, no.1, pp.64-68, 2016 (Released:2016-02-26)

参考文献数

17

被引用文献数

2

---

Using mitochondrial DNA sequences, we surveyed genetic features of 12 individuals of Cynops pyrrhogaster introduced into Hachijojima Island, in order to estimate their possible origin in the main islands of Japan. The phylogenetic analysis revealed that the 12 examined newts of the introduced population display no genetic diversity and share characteristics with the conspecific population of Shikoku and thus belong to the WESTERN Clade proposed by earlier studies. Our results suggest that the Hachijojima population, having experienced a drastic founder effect, stems from very few individuals from the Shikoku District approximately 650 km to the west.

著者

Tze-Kiong Er Eing-Mei Tsai Li-Yu Tsai Ying-Chin Ko Jau-Nan Lee

出版者

The Japanese Society of Toxicology

雑誌

The Journal of Toxicological Sciences (ISSN:03881350)

巻号頁・発行日

vol.31, no.1, pp.75-82, 2006 (Released:2006-03-10)

参考文献数

46

被引用文献数

9 9

---

Semen samples were obtained from 30 volunteers who had never consumed betel quid. Swim-up spermatozoa from the 30 seminal samples of non-betel quid chewers and also non-smokers, usually not exposed to passive smoking, were treated in vitro with arecoline at different concentrations to evaluate the action of these drugs on sperm motility. Highly motile sperms were collected and divided into 5 equal fractions. Four fractions were supplemented with various concentrations of arecoline and one as control. The study was carried out at time 0 and +1, +2, +3 and +4 hr of incubation. Sperm cells were also extracted and blotted with COX-2 antibody after arecoline treatment after 4 hr incubation. The sperm motility parameters, i.e., motility, average path velocity, curvilinear velocity, straight-line velocity and linearity, were significantly decreased after arecoline treatment. In vitro, arecoline induces the COX-2 expression of sperm cells in a dose-dependent manner. This is the first report to demonstrate that arecoline may mediate COX-2 expression in human sperms, resulting in inflammation response. This situation may act on the structure responsible for the flagellar motion and cause the reduction of sperm motility.

著者

永澤 貴昭 黒坂 裕香 田中 智美 町田 修一 湊 久美子 Takaaki NAGASAWA Yuka KUROSAKA Tomomi HASEGAWA-TANAKA Shuichi MACHIDA Kumiko MINATO

出版者

和洋女子大学

雑誌

和洋女子大学紀要 = The journal of Wayo Women's University (ISSN:18846351)

巻号頁・発行日

vol.64, pp.97-105, 2023-03-01

---

運動部に所属する男子大学生アスリートの食事調査結果を用いて、栄養摂取状況の特徴を評価した。さらに、食品群別摂取頻度による評価点を算出して、エネルギー、栄養素摂取量や各栄養素摂取量による評価点との関連性を検討し、アスリートの食生活バランスの評価に用いることができる簡易な方法について考察することを目的とした。食事調査の結果、対象集団にはエネルギー、栄養素摂取量が身体活動量に見合わないものが複数いた。一方で、サプリメントやプロテインを利用している者が多数おり、食事に関して無関心ではないことが窺われた。食品群別摂取頻度による評価点を用いた簡易な食生活評価法については、たんぱく質、鉄、カルシウム、ビタミンB1など、アスリートにとって重要な栄養素摂取量との有意な関連性を認めた。さらに、食品群別摂取頻度の得点と8項目のエネルギーと栄養素摂取量を、食事摂取基準の推奨量ならびにアスリートの推奨量と比較して得点化した栄養素摂取量評価得点を算出し関連について分析を行ったところ、有意な関連性が認められた。10種の食品群別摂取頻度を把握することは、アスリートの食生活とそれに付随する栄養摂取状況の概要について評価することができると考えられ、栄養アセスメントの一次的なスクリーニング評価に活用できる可能性が示唆された。

著者

Ji-Hyun JANG Myoung Geun LEE Sang Uk WOO Chung Ok LEE Jin-Kyu YI Duck-Su KIM

出版者

The Japanese Society for Dental Materials and Devices

雑誌

Dental Materials Journal (ISSN:02874547)

巻号頁・発行日

vol.35, no.4, pp.606-612, 2016-07-29 (Released:2016-07-30)

参考文献数

33

被引用文献数

33 34

---

This study compared the dentin bond strength of a new universal adhesive with that of contemporary multi-step dentin adhesives. Six experimental groups were prepared according to the adhesives used and their application modes: Optibond FL (OB), Adper Single Bond Plus (SB), One-Step Plus (OS), Clearfil SE Bond (CS), All-Bond Universal using etch-and-rinse mode (ABE), and AllBond Universal using self-etch mode (ABS). Micro-tensile bond strength (µTBS) and failure mode were evaluated for each group. The bonded interface was analyzed using transmission electron microscopy (TEM). As a result, µTBS of 6 experimental groups was followed as: OB=ABE=SE=ABS>SB>OS group. TEM micrographs of ABE and ABS groups revealed a homogenous adhesive layer formation. In conclusion, a new universal adhesive can make reliable bond to dentin, regardless of the application mode.

著者

Kenzo Hiraoka Yuji Sakai Hiroyuki Kubota Satoshi Ninomiya Stephanie Rankin-Turner

出版者

The Mass Spectrometry Society of Japan

雑誌

Mass Spectrometry (ISSN:2187137X)

巻号頁・発行日

vol.12, no.1, pp.A0114, 2023-01-31 (Released:2023-01-31)

参考文献数

35

被引用文献数

1

---

Among the various types of cluster secondary ion mass spectrometry (SIMS), electrospray droplet impact/secondary ion mass spectrometry (EDI/SIMS) is unique due to its high ionization efficiency and non-selective atomic/molecular-level surface etching ability. In this study, EDI/SIMS was applied to the non-selective etching of synthetic polymers of polystyrene (PS) and poly(9,9-di-n-octylfluonyl-2,7diyl) (PFO) deposited on a silicon substrate. The polymers gave characteristic fragment ions and the mass spectra remained unchanged with prolonged EDI irradiation time, indicating that non-selective etching can be achieved by EDI irradiation, a finding that is consistent with our previous reports based on EDI/X-ray photoelectron spectroscopy analyses. From the irradiation time and film thickness, the etching rates for PS and PFO were roughly estimated to be 0.6 nm/min and 0.15 nm/min, respectively, under the experimental conditions that were used. After the depletion of polymer sample on the surface, ion signals originating from the exposed silicon substrate were observed. This indicates that EDI/SIMS is applicable to the analysis of the interface of multilayered films composed of organic and inorganic materials.

著者

Atsushi Hozawa Kozo Tanno Naoki Nakaya Tomohiro Nakamura Naho Tsuchiya Takumi Hirata Akira Narita Mana Kogure Kotaro Nochioka Ryohei Sasaki Nobuyuki Takanashi Kotaro Otsuka Kiyomi Sakata Shinichi Kuriyama Masahiro Kikuya Osamu Tanabe Junichi Sugawara Kichiya Suzuki Yoichi Suzuki Eiichi N Kodama Nobuo Fuse Hideyasu Kiyomoto Hiroaki Tomita Akira Uruno Yohei Hamanaka Hirohito Metoki Mami Ishikuro Taku Obara Tomoko Kobayashi Kazuyuki Kitatani Takako Takai-Igarashi Soichi Ogishima Mamoru Satoh Hideki Ohmomo Akito Tsuboi Shinichi Egawa Tadashi Ishii Kiyoshi Ito Sadayoshi Ito Yasuyuki Taki Naoko Minegishi Naoto Ishii Masao Nagasaki Kazuhiko Igarashi Seizo Koshiba Ritsuko Shimizu Gen Tamiya Keiko Nakayama Hozumi Motohashi Jun Yasuda Atsushi Shimizu Tsuyoshi Hachiya Yuh Shiwa Teiji Tominaga Hiroshi Tanaka Kotaro Oyama Ryoichi Tanaka Hiroshi Kawame Akimune Fukushima Yasushi Ishigaki Tomoharu Tokutomi Noriko Osumi Tadao Kobayashi Fuji Nagami Hiroaki Hashizume Tomohiko Arai Yoshio Kawaguchi Shinichi Higuchi Masaki Sakaida Ryujin Endo Satoshi Nishizuka Ichiro Tsuji Jiro Hitomi Motoyuki Nakamura Kuniaki Ogasawara Nobuo Yaegashi Kengo Kinoshita Shigeo Kure Akio Sakai Seiichiro Kobayashi Kenji Sobue Makoto Sasaki Masayuki Yamamoto

出版者

Japan Epidemiological Association

雑誌

Journal of Epidemiology (ISSN:09175040)

巻号頁・発行日

vol.31, no.1, pp.65-76, 2021-01-05 (Released:2021-01-05)

参考文献数

34

被引用文献数

54 78

---

Background: We established a community-based cohort study to assess the long-term impact of the Great East Japan Earthquake on disaster victims and gene-environment interactions on the incidence of major diseases, such as cancer and cardiovascular diseases.Methods: We asked participants to join our cohort in the health check-up settings and assessment center based settings. Inclusion criteria were aged 20 years or over and living in Miyagi or Iwate Prefecture. We obtained information on lifestyle, effect of disaster, blood, and urine information (Type 1 survey), and some detailed measurements (Type 2 survey), such as carotid echography and calcaneal ultrasound bone mineral density. All participants agreed to measure genome information and to distribute their information widely.Results: As a result, 87,865 gave their informed consent to join our study. Participation rate at health check-up site was about 70%. The participants in the Type 1 survey were more likely to have psychological distress than those in the Type 2 survey, and women were more likely to have psychological distress than men. Additionally, coastal residents were more likely to have higher degrees of psychological distress than inland residents, regardless of sex.Conclusion: This cohort comprised a large sample size and it contains information on the natural disaster, genome information, and metabolome information. This cohort also had several detailed measurements. Using this cohort enabled us to clarify the long-term effect of the disaster and also to establish personalized prevention based on genome, metabolome, and other omics information.

著者

Takako GOTOHDA Aki KUWADA Kyoji MORITA Shin-ichi KUBO Itsuo TOKUNAGA

出版者

The Japanese Society of Toxicology

雑誌

The Journal of Toxicological Sciences (ISSN:03881350)

巻号頁・発行日

vol.25, no.3, pp.223-231, 2000-08-17 (Released:2008-02-21)

参考文献数

39

被引用文献数

11 12

---

Toluene, a commonly used industrial solvent, is known to be toxic to both neuronal and glial cells, and has been shown to increase the immunoreactivity of glial fibrillary acidic protein(GFAP)in the brain. However, the mechanism of toluene-induced GFAP expression is poorly understood. Recently, GFAP mRNA expression in cultured astrocytes has been shown to be modulated by various steroid hormones, such as progesterone, testosterone, and their 5α-reduced metabolites. Therefore, it seems possible that steroid hormones may play a potential role in the enhancement of GFAP expression observed following toluene exposure. To address this possibility, the effect of toluene inhalation on the expression of mRNAs encoding GFAP and steroidogenic enzymes in rat brain was examined. Toluene exposure increased GFAP protein contents without any significant alteration in GFAP mRNA levels in the hippocampus. In contrast, the elevation of both GFAP protein contents and its mRNA levels was observed in the cerebellum following toluene exposure. Further studies indicated that toluene exposure increased steroid 5α-reductase(5α-R)mRNA levels prior to the elevation of GFAP mRNA in the cerebellum, whereas neither 5α-R nor GFAP mRNA levels in the hippocampus were significantly affected by toluene exposure. These results suggest that toluene inhalation may enhance GFAP gene expression in the rat cerebellum, and propose the possibility that the elevation of 5α-R expression, and hence 5α-reduced metabolites of steroid hormones, is presumably related to toluene-induced GFAP mRNA expression.

著者

張 淑倩 SHU-CHIEN CHANG 湘北短期大学非常勤講師 Shohoku College

巻号頁・発行日

no.28, pp.89-99, 2007-03-31

---

Chinese language has many words containing a color related Chinese character. These words not simply indicate colors but also imply other meanings deriving from these colors. In China, colors often have symbolic meanings. The present paper discusses these social, cultural, and ideologieal meanings of colors used in Chinese language.

著者

Geoffrey H. GRANTHAM M. SATISH-KUMAR Kenji HORIE Henriette UECKERMANN H

出版者

Japan Association of Mineralogical Sciences

雑誌

Journal of Mineralogical and Petrological Sciences (ISSN:13456296)

巻号頁・発行日

pp.230125, (Released:2023-05-16)

---

The ~550 Ma Kuunga Orogeny extends from the Damara in Namibia, through the Zambesi and Lurio orogenic belts in Zambia and Mozambique, southern Africa, through Dronning Maud Land and Princess Elizabeth Land, Antarctica into western Australia. Sverdrupfjella is located at the western end of Dronning Maud Land where the Kuunga Orogeny is inferred to post-date and overprint the East African Orogeny.Three complexes are recognized in Sverdrupfjella western Dronning Maud Land , Antarctica. A western basal ~1140 Ma Jutulrora Complex, consisting mostly of arc-related tonalitic trondjhemitic orthogneiss with evolved Sr - Nd isotopic signatures with TDm ages >2 Ga. It is structurally overlain by the Fuglefjellet Complex, comprising supracrustal ~800 – 900 Ma carbonates intercalated with quartzo-feldspathic gneisses with detrital zircons of ~1000 - 1200 Ma age with ~500 Ma overgrowths. The Fuglefjellet Complex is overlain in the east by the Rootshorga Complex containing paragneisses with minor orthogneisses (~1100 – 1200 Ma), intruded by granitic orthogneiss of similar age. Strontium - Nd isotopic signatures from the Rootshorga Complex has TDm ages <1.8 Ga.D1 and D2 planar fabrics typically dip to SE with vergence top-to-NW in all complexes. D3 deformation verges top-to-the-SE. In the Jutulrora Complex, D3 comprises ~100m scale folds with NW dipping axial planes, cut by SE dipping dilational granite sheets. In the Rootshorga Complex D3 is characterised by syntectonic granite veins with extensional and compressional displacements with top-to-the SE shear. Discordancies are consistent with low angle thrust planes at Fuglefjellet and Kvikjolen with probable repetition of carbonate layers.Zircon ages of the granitic sheets are 490 - 500Ma. Strontium and Nd isotopic signatures of the granitic sheets intruded into all complexes are consistent with melting of Jutulrora Complex crust with Archaean and Mesoproterozoic xenocrysts in some samples. Top-to-SE shear zones displace pegmatites with an inferred age of 520 Ma and are syntectonic with layer parallel ~490 Ma granite sheets.P-T-t studies from the Rootshorga Complex yield isothermal decompression paths at ~ 800 – 900 oC with decompression from ~1.4 GPa at ~570Ma to ~700oC and ~0.7 GPa at ~500Ma whereas P-T-t estimates from the Jutulrora Complex are ~ 600 – 700 oC and <~0.8 GPa at ~500 Ma with a path consistent with crustal loading. The Rootshorga and Fuglefjellet Complex are inferred to comprise a mega-nappe, emplaced during the Kuunga Orogeny ~500 Ma ago, over the footwall Jutulrora Complex. Aerogravity, satellite gravity and seismic tomography data reflecting unusually thick crust are consistent with this interpretation.

著者

Takayuki KIKUCHI Yasushi TAKAGI Jyoji NAKAGAWARA Tsukasa UENO Shiho UBUKATA Kiyohiro HOUKIN Yoshio ARAKI Jun C TAKAHASHI Hiroyuki NAKASE Toshiya MURAI Susumu MIYAMOTO COSMO-Japan Study Group

出版者

The Japan Neurosurgical Society

雑誌

Neurologia medico-chirurgica (ISSN:04708105)

巻号頁・発行日

pp.2023-0041, (Released:2023-05-11)

参考文献数

24

---

Cognitive impairment in adult patients with moyamoya disease (MMD) is sometimes overlooked and can occur in patients with no ischemic or hemorrhagic lesions. Better profiling and reliable diagnostic methods that characterize the group and associate the impairments and pathology of MMD are required in order to deliver appropriate treatments and support. The potential of 123I-iomazenil single-photon emission computed tomography (SPECT) for this issue has been reported in some studies, but the universality of this method remains unclear. A multicenter study of adult patients (aged 18-60 years) with MMD who experienced difficulties in social lives despite normal activities of daily living was implemented to delineate the common characteristics of this group of patients. In this study, iomazenil SPECT, besides patient characteristics, cognitive functions, and conventional imaging, was acquired to examine whether this method is suitable as a universal diagnostic tool. A total of 36 patients from 12 institutes in Japan were included in this study. Domain scores of world health organization quality of life 26 indicated low self-rating in physical health and psychological domains. The percentages of patients who had <85 in each index were 27.8%-33.3% in the WAIS-III and 16.7%-47.2% in the Wechsler Memory Scale-Revised. The group analysis of iomazenil SPECT demonstrated a decreased accumulation in the bilateral medial frontal areas in comparison with the normal control, whereas there were no specific characteristics on conventional imaging in the cohort. Iomazenil SPECT is a possible universal diagnostic method for the extraction of patients with cognitive impairment in MMD.

著者

Natalia GOGOLEVA Zeynab Javanfekr SHAHRI Atsushi NODA Ching-Wei LIAO Arata WAKIMOTO Yuri INOUE Hyojung JEON Satoru TAKAHASHI Michito HAMADA

出版者

Japanese Association for Laboratory Animal Science

雑誌

Experimental Animals (ISSN:13411357)

巻号頁・発行日

pp.23-0044, (Released:2023-05-12)

被引用文献数

1

---

Adeno-associated virus serotype 9 (AAV9) has become a popular tool for gene transfer because of its ability to cross the blood-brain barrier and efficiently transduce genetic material into a variety of cell types. The study utilized GRR (Green-to-Red Reporter) mouse embryos, in which the expression of iCre results in the disappearance of Green Fluorescent Protein (GFP) expression and the detection of Discosoma sp. Red Fluorescent Protein (DsRed) expression by intraplacental injection. Our results demonstrate that AAV9-CMV-iCre can transduce multiple organs in embryos at developmental stages E9.5–E11.5, including the liver, heart, brain, thymus, and intestine. These findings suggest that intraplacental injection of AAV9-CMV-iCre is a viable method for the widespread transduction of GRR mouse embryos.

著者

Mako Nagayoshi Kenji Takeuchi Yudai Tamada Yasufumi Kato Yoko Kubo Rieko Okada Takashi Tamura Asahi Hishida Jun Otonari Hiroaki Ikezaki Yuichiro Nishida Chisato Shimanoe Yuriko N. Koyanagi Keitaro Matsuo Haruo Mikami Miho Kusakabe Daisaku Nishimoto Keiichi Shibuya Sadao Suzuki Takeshi Nishiyama Etsuko Ozaki Isao Watanabe Kiyonori Kuriki Naoyuki Takashima Aya Kadota Kokichi Arisawa Sakurako Katsuura-Kamano Kenji Wakai

出版者

Japan Epidemiological Association

雑誌

Journal of Epidemiology (ISSN:09175040)

巻号頁・発行日

vol.33, no.5, pp.236-245, 2023-05-05 (Released:2023-05-05)

参考文献数

50

被引用文献数

2

---

Background: Stress coping strategies are related to health outcomes. However, there is no clear evidence for sex differences between stress-coping strategies and mortality. We investigated the relationship between all-cause mortality and stress-coping strategies, focusing on sex differences among Japanese adults.Methods: A total of 79,580 individuals aged 35–69 years participated in the Japan Multi-Institutional Collaborative Cohort Study between 2004 and 2014 and were followed up for mortality. The frequency of use of the five coping strategies was assessed using a questionnaire. Sex-specific, multivariable-adjusted hazard ratios (HRs) for using each coping strategy (“sometimes,” and “often/very often” use versus “very few” use) were computed for all-cause mortality. Furthermore, relationships were analyzed in specific follow-up periods when the proportion assumption was violated.Results: During the follow-up (median: 8.5 years), 1,861 mortalities were recorded. In women, three coping strategies were related to lower total mortality. The HRs for “sometimes” were 0.81 (95% confidence interval [CI], 0.67–0.97) for emotional expression, 0.79 (95% CI, 0.66–0.95) for emotional support-seeking, and 0.80 (95% CI, 0.66–0.98) for disengagement. Men who “sometimes” used emotional expression and sometimes or often used problem-solving and positive reappraisal had a 15–41% lower HRs for all-cause mortality. However, those relationships were dependent on the follow-up period. There was evidence that sex modified the relationships between emotional support-seeking and all-cause mortality (P for interaction = 0.03).Conclusion: In a large Japanese sample, selected coping strategies were associated with all-cause mortality. The relationship of emotional support-seeking was different between men and women.

著者

Deepak Gautam Jun-ichi Takada

出版者

The Institute of Electronics, Information and Communication Engineers

雑誌

IEICE Communications Express (ISSN:21870136)

巻号頁・発行日

vol.12, no.5, pp.175-180, 2023-05-01 (Released:2023-05-01)

参考文献数

7

---

This paper presents development of passive channel sounder using software defined radio based receivers and commercial transmitter operating in cellular network. Accuracy of developed channel sounder is verified by over-the-air path gain measurement in outdoor open space. For evaluation, line-of-sight path gain is estimated using correlation method and is compared with theoretical path gain.

著者

杉江 栄一 Ei-ichi Sugie

雑誌

中亰法學 = Chukyo hogaku (ISSN:02862654)

巻号頁・発行日

vol.15, no.3, pp.1-8, 1981-01-20

著者

Doo-Soo KIM Il-Tak HAN Tae-Wan KIM Ho-Sang KWON Kyung-Tae KIM

出版者

The Institute of Electronics, Information and Communication Engineers

雑誌

IEICE TRANSACTIONS on Electronics (ISSN:09168516)

巻号頁・発行日

vol.E106-C, no.5, pp.184-187, 2023-05-01

---

In this paper, the planar subarray structure to be optimized by using random search method for large active array antenna is presented. Although MPSL of the optimized subarray structure is 1.09dB higher, G/T of the optimized subarray structure is 2.07dB higher than the reference subarray structure.

著者

Xin-Liang Lu He-Long Cao Ke-Da Qian

出版者

The Japanese Society of Internal Medicine

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

vol.47, no.20, pp.1797-1798, 2008 (Released:2008-10-15)

参考文献数

6

被引用文献数

8 8

---

A rare case is reported with a large foreign body in the upper gastrointestinal tract. A 19-year-old girl accidentally swallowed her toothbrush which was successfully removed via endoscopy using a polypectomy snare under topical pharyngeal anesthesia. The extracted toothbrush was 20 cm long, and it had the characteristic radiographic image.

著者

Daehoon Kim Pil-Sung Yang Tae-Hoon Kim Jae-Sun Uhm Junbeom Park Hui-Nam Pak Moon-Hyoung Lee Boyoung Joung

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

vol.82, no.8, pp.1999-2006, 2018-07-25 (Released:2018-07-25)

参考文献数

36

被引用文献数

8 9

---

Background:Both atrial fibrillation (AF) and osteoporosis are common in older adults. The purpose of this study was to investigate whether comorbid AF in patients with osteoporosis is associated with fracture incidence, or death after fracture.Methods and Results:From the National Health Insurance Service database of Korea, we selected 31,778 patients with osteoporosis. During a median follow-up of 48 months, the incidence of bone fractures was higher in AF patients than in non-AF patients (3.20 vs. 2.18 per 100 person-years), respectively. In the multivariate Cox regression analysis, AF was associated with fracture independently of other risk factors with an adjusted hazard ratio (HR) of 1.21 (95% confidence interval [CI], 1.02–1.41; P=0.031). The mortality rate after fracture was significantly higher in AF patients than it was in non-AF patients (adjusted HR, 1.92; 95% CI, 1.35–3.27; P=0.016). After propensity score-matching, AF was consistently associated with a higher risk of osteoporotic fracture and subsequent death after fracture. In AF patients, older age, female sex, being underweight (body mass index <18.5 kg/m2), decreased physical activity (exercise <3 times/week), history of stroke or transient ischemic attack, thiazide use, sedative use, and higher CHADS2(≥2 points) or CHA2DS2-VASc (≥2 points) scores were associated with the incidence of fractures.Conclusions:Comorbid AF in patients with osteoporosis was associated with an increased risk of bone fracture and death after fracture.

著者

Yu-Ling Chen Shihmin Lo Jen-Son Cheng

出版者

Fuji Technology Press Ltd.

雑誌

Journal of Advanced Computational Intelligence and Intelligent Informatics (ISSN:13430130)

巻号頁・発行日

vol.27, no.2, pp.281-291, 2023-03-20 (Released:2023-03-20)

参考文献数

41

---

Objectives: In the past, an inherent dilemma in the education field was the difficulty in stimulating self-regulated learning. Flipped education, i.e., flipped teaching and learning, changed the teaching model, with a strategy of increasing students’ active learning during class time through a transformation of teaching and learning methods that enable students to build learning and knowledge on their own. This study investigates the impact of field-based flipped courses on college students taking up self-regulated learning and their learning performance. Methods: This study considers a national university in central Taiwan that adopts 34 field flipped teaching courses and 796 non-degree students from four colleges across all grades as the research objects, and conducts statistical analysis using descriptive statistics, t-test, ANOVA, Pearson’s correlation, and regression analysis on questionnaires to evaluate the association among variables. Findings: 1. With respect to the understanding of the uniqueness of field-based flipped teaching before and after the courses, there were differences among students in the Colleges of Education, Humanities, and Management. 2. In terms of students’ learning performance in the course pertaining to mastery over core literacy, there were differences between students of the Colleges of Education and Humanities at the beginning of the flipped-learning course. 3. There were differences among the students of Colleges of Education, Humanities, and Science and Technology in the later stage of the flipped-learning course. 4. Differences were found in the pre-test of learning performance at the grade level. 5. Self-regulated learning correlated with learning performance. 6. Field-based flipped teaching correlated with learning performance. 7. Self-regulated learning had a mediating effect on field-based flipped teaching and learning performance. Innovations: There is a little systematic discussion on the emergence and impact of flipped teaching in higher education currently in Taiwan. The authors found correlations among flipped teaching, self-regulated learning, and learning performance from the data, as well as discovered that self-regulated learning had a mediating effect on learning performance in field-based flipped teaching. Value: Making the university, when the curriculum arrangement and the development of the unique curriculum map of higher education in the future, possible to be linked with the local revitalization thinking in addition to the general curriculum, as well as being closely integrated with the local people and matters through field-flipped courses, and sustainably interacting therewith to practice university social responsibility.