著者
徳田 孝明/渡邉 茂/村田 暁/村上 雅洋/杉村 直哉/平井 千晴
出版者
東北職業能力開発大学校付属 秋田職業能力開発短期大学校
雑誌
東北職業能力開発大学校附属秋田職業能力開発短期大学校紀要
巻号頁・発行日
vol.17, pp.36-39, 2012-05

本校では平成19年度より、小中高校生に対して様々なキャリア教育支援を実施してきたが、そのひとつに小学生を対象に3年前から行っている産業教育展での職業体験の支援がある。今年度は職業体験を効果的に実施するために、事前に適職診断を行い自分の適する仕事を理解した上で職業体験を実施する仕組みを作り上げたので報告する。
著者
かりまた しげひさ Karimata Shigehisa / 狩俣 繁久
出版者
琉球大学国際沖縄研究所
雑誌
国際琉球沖縄論集 = International review of Ryukyuan and Okinawan studies (ISSN:21867933)
巻号頁・発行日
no.5, pp.1-13, 2016-02

琉球列島全域の言語地理学的な調査の資料を使って、構造的比較言語地理学を基礎にしながら、音韻論、文法論、語彙論等の基礎研究と比較言語学、言語類型論、言語接触論等の応用研究を融合させて、言語系統樹の研究を行なえば、琉球列島に人々が渡来、定着した過程を総合的に解明できる。言語史研究の方法として方言系統地理学を確立することを提案する。This paper advocates the establishment of a field of "dialectal phylogenetic geography" as a method of historical linguistics. Linguistic phylogenetic research of Ryukyuan languages and dialects will clarify the historical processes of people's migration and settlement on the Ryukyu Islands more comprehensively. By fusing basic research such as phonology, grammar, and lexicology, with applied research, such as comparative linguistics, linguistic typology, and language contact, utilizing research materials from linguistic geography that is based on structural linguistic geography in the historical and comparative field, can we better understand these processes.
著者
Toshiaki Toyota Takeshi Morimoto Hiroki Shiomi Kenji Ando Koh Ono Satoshi Shizuta Takao Kato Naritatsu Saito Yutaka Furukawa Yoshihisa Nakagawa Minoru Horie Takeshi Kimura on behalf of the CREDO-Kyoto PCI/CABG Registry Cohort-2 Investigators
出版者
日本循環器学会
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
pp.CJ-16-0987, (Released:2017-02-07)
参考文献数
31
被引用文献数
10

Background:Few studies have evaluated the prevalence and clinical outcomes of ad hoc percutaneous coronary intervention (PCI), performing diagnostic coronary angiography and PCI in the same session, in stable coronary artery disease (CAD) patients.Methods and Results:From the CREDO-Kyoto PCI/CABG registry cohort-2, 6,943 patients were analyzed as having stable CAD and undergoing first PCI. Ad hoc PCI and non-ad hoc PCI were performed in 1,722 (24.8%) and 5,221 (75.1%) patients, respectively. The cumulative 5-year incidence and adjusted risk for all-cause death were not significantly different between the 2 groups (15% vs. 15%, P=0.53; hazard ratio: 1.15, 95% confidence interval: 0.98–1.35, P=0.08). Ad hoc PCI relative to non-ad hoc PCI was associated with neutral risk for myocardial infarction, any coronary revascularization, and bleeding, but was associated with a trend towards lower risk for stroke (hazard ratio: 0.78, 95% confidence interval: 0.60–1.02, P=0.06).Conclusions:Ad hoc PCI in stable CAD patients was associated with at least comparable 5-year clinical outcomes as with non-ad hoc PCI. Considering patients’ preference and the cost-saving, the ad hoc PCI strategy might be a safe and attractive option for patients with stable CAD, although the prevalence of ad hoc PCI was low in the current study population.
著者
宮澤 修平 岡野 和夫 下村 直之 / 川原 哲也 浅野 修 吉村 寛幸 宮本 光明 佐久間 義範 村本 賢三 尾葉石 浩 原田 耕吉 梶間 隆 山田 浩司 角田 創 片山 敏 阿部 信也 浅川 直樹 左右田 茂 堀江 透 里 忠 町田 善正 片山 幸一 山津 功 Isao YAMATSU
出版者
The Pharmaceutical Society of Japan
雑誌
Chemical and Pharmaceutical Bulletin (ISSN:00092363)
巻号頁・発行日
vol.39, no.12, pp.3215-3220, 1991-12-25 (Released:2008-03-31)
参考文献数
27
被引用文献数
6 9

A series of triazolodiazepines was synthesized and evaluated for anti-platelet activating factor (PAF) activities. Structure-activity relationship (SAR) studies on this series revealed that the introduction of a methyl group into the 8-position of the thienodiazepine nucleus can lead to a lengthening of the duration of action. Introduction of a methyl group produced an asymmetric center and the enantiomers so formed were separated with an optical resolving column. In the in vitro assay system, the (+)-isomers displayed 50-200 times more potent anti-PAF activity than the (-)-isomers. After comparison of toxicology and pharmacokinetics, (+)-6-(2-chlorophenyl)-3-cyclopropanecarbonyl-8, 11-dimethyl-2, 3, 4, 5-tetrahydro-8H-pyrido[4', 3' : 4, 5]thieno[3, 2-f][1, 2, 4]triazolo[4, 3-a][1, 4]diazepine (35(+)-isomer, E6123) was selected from among the compounds synthesized as a candidate for clinical study.
著者
玄 善允/藤井 幸之助 藤井 幸之助
出版者
神戸女学院大学
雑誌
女性学評論 (ISSN:09136630)
巻号頁・発行日
vol.27, pp.87-118, 2013-03

Yongwanggung (Ryuogu/Ryuokyu),a renowned shamanism mecca for the first generation of Korean residents in Japan(especially,female residents from Jeju Island)disappeared,following an eviction order from the local government.It was only a few years before its dismantling that serious research started on its facilities and prayers.Previous research,however,left several important questions unanswered.This paper,mainly based on interviews of prayers and their family members,investigates and rediscovers the meaning of the `prayer community',and argues that shamanistic rituals carried out at several places,including Ryuogu,prayers home,Buddhist temples called Chosendera (Korean temples in Japan),are part of the first generation female residents' prayer activities,which are in turn part of the traditional culture of the first generation Korean residents.It also argues that though the rituals originated from Jeju island,they are adapted and transformed for Korean residents in Japan.From the deviation,we are able to read the life strategies of the first generation female residents.However,the prayer community,composed of mostly the first generation with some exceptional second generation residents,is destined to be isolated and separated from other generations and communities. The Shamanistic rituals of Korean residents in Japan are the scenes where oppositions or conflicts causedby the generation gaps,and educational and cultural background differences are revealed.
著者
門田 重利 高森 靖 / 菊池 徹 田中 謙 浴本 久雄 Hisao EKIMOTO
出版者
The Pharmaceutical Society of Japan
雑誌
Chemical and Pharmaceutical Bulletin (ISSN:00092363)
巻号頁・発行日
vol.38, no.10, pp.2687-2697, 1990-10-25 (Released:2008-03-31)
参考文献数
22
被引用文献数
28 54

Woodfruticosin (woodfordin C), a new cyclic dimeric hydrolyzable tannin having an inhibitory activity toward deoxyribonucleic acid (DNA) topoisomerase II, has been isolated from the leaves of Woodfordia fruticosa KURZ (Lythraceae) along with three known flavonol glycosides and three known flavonol glycoside gallates. The structure of woodfruticosin (woodfordin C) was determined by the use of two-dimensional nuclear magnetic resonance (2-D NMR) spectroscopy including heteronuclear multiple quantum coherence (HMQC) and heteronuclear mucltiple bond connectivity (HMBC) techniques. Detailed analyses of the proton and carbon-13 NMR (1H-and 13C-NMR) spectra of six known flavonoids were performed.
著者
渡辺 睦行/坂尾 眞理 坂尾 眞理
出版者
昭和女子大学
雑誌
學苑 (ISSN:13480103)
巻号頁・発行日
vol.902, pp.55-58, 2015-12-01

Intravital lipid peroxidation is associated with the onset of diseases including atherosclerosis and cancer. Antioxidants such as polyphenols and peptides have been reported to prevent peroxidation. Our laboratory previously found that soybean tempeh, a traditional fermented soy food from Indonesia, possesses stronger antioxidant activity than unfermented soybeans. The aim of the present study is to establish whether chickpea tempeh also demonstrates elevated antioxidant properties compared with unfermented chickpeas using DPPH radical scavenging activity and β-carotene bleaching assays. Our results showed that total polyphenol content in chickpeas increased by up to 40% during fermentation. In addition, the DPPH assay revealed that the antioxidant activity of the chickpeas tempeh was stronger than that of unfermented chickpeas.