著者
河合 俊雄
出版者
心理学評論刊行会
雑誌
心理学評論 (ISSN:03861058)
巻号頁・発行日
vol.55, no.1, pp.195-202, 2012 (Released:2018-08-18)
著者
坂口 順一 国分 紀之
出版者
一般社団法人 日本高圧力技術協会
雑誌
圧力技術 (ISSN:03870154)
巻号頁・発行日
vol.42, no.3, pp.121-129, 2004 (Released:2004-09-15)
参考文献数
8
被引用文献数
2

Hydrogen energy system is one of the solutions for the global issue of greenhouse gases emission. The hydrogen supply chain system i. e. manufacturing, transportation and storage shall be discussed for the development of hydrogen Society. From this standpoint, thermal efficiency and CO2 emission of both hydrogen energy system and fossil energy system are evaluated in the “Well to Wheel” and “Well to Bus”.

1 0 0 0 自由論

著者
ミル著 斉藤悦則訳
出版者
光文社
巻号頁・発行日
2012
著者
天竺桂 弘子 佐藤 令一
出版者
東京農工大学
雑誌
挑戦的研究(開拓)
巻号頁・発行日
2020-07-30

宿主体内への侵入は、多胚性寄生蜂において寄生成功の必須要件である。この侵入において、多胚性寄生蜂の桑実胚は宿主組織内に損傷を与えることなく侵入し、むしろ宿主は桑実胚を積極的に迎え入れる。このような組織親和的侵入は、一般的に動物界で広く知られる遠縁種間の急性型移植拒絶反応を回避するユニークな現象で、その仕組みとして分子擬態が示唆されてきた。本研究では申請者らがこれまでに多胚性寄生蜂の胚発生期の遺伝子発現解析で得られた情報を基に、組織親和的侵入の仕組みを解明することを目的とする。
著者
湯川 拓
出版者
JAPAN ASSOCIATION OF INTERNATIONAL RELATIONS
雑誌
国際政治 (ISSN:04542215)
巻号頁・発行日
vol.2011, no.164, pp.164_58-71, 2011-02-20 (Released:2013-05-22)
参考文献数
38

What types of characteristics do the diplomatic relationships of countries with unstable “regime security” exhibit? These are countries where the use of force is used to challenge the authority of the central government, for example, by means of revolution; civil war; or coup d' état. According to the existing literature, the argument that “when domestic governance within a country is unstable, that country's relationship with other countries will also be unstable” seems to dominate most research.In contrast to these works, this paper aims to conceptualize the mechanism where countries choose to cooperate multilaterally and internationally, in order to heighten their own regime security. In particular, two types of international institutions which exist for the purpose of heightening domestic security will be introduced. The first type of institution, which is responsible for defining the concept of what a “domestic political regime” should be, seeks to actively impose sanctions on those countries which defy the concept. On the other hand, the second type of institution seeks to mutually recognize the legitimacy of its member countries' political regimes, regardless of the form that these regimes might take. In this way, the second type of institution can be described as being “negative” in nature. Examples of such institutions include Mercosur and ASEAN. This paper will demonstrate that the role of these institutions goes beyond stabilizing international relationships, but also extends into the realm of reinforcing regime security, which is the prior concern of its member countries.Moreover, since the stance adopted by this paper is that “regime security and the international institutions are closely linked”, it will also add a fresh perspective to the existing literature on the evolution of the international norms. The evolution of the international norms refers to the change in the perspective of countries over time, when they choose to replace policies of mutual non-interference with new policies. Originally, such changes used to be interpreted as a “transition in the international norms”, or as “the waning of sovereignty”. However, this paper argues differently. Instead of seeing changes in the international regime as a “break” in the existing state of affairs, this paper proposes that the change from mutual non-interference to mutual cooperation is in fact a form of continuity in the international norm, borne out of the desire of countries to heighten their own regime security.
著者
Melendo Jose Manuel Almodovar Verdejo Juan Ramon Jimenez de la Blanca Ismael Dominguez Sanchez
出版者
ARCHITECTURAL INSTITUTE OF JAPAN (AIJ), ARCHITECTURAL INSTITUTE OF KOREA (AIK), ARCHITECTURAL SOCIETY OF CHINA (ASC)
雑誌
Journal of Asian Architecture and Building Engineering (ISSN:13467581)
巻号頁・発行日
vol.13, no.1, pp.41-48, 2014-01-15 (Released:2014-01-15)
参考文献数
25
被引用文献数
3

Kings Road House has become an icon of early modern architecture. This innovative house, described by Schindler as ″a cooperative dwelling for two young couples″, was considered by Reyner Banham to be a totally new beginning. Although many papers devoted to the house have been published, no research has been conducted into its relationship with the interpreted characteristics of Japanese architecture or the sources from which Schindler may have obtained information about Japan in 1921 without ever having traveled to the country. In this paper, the authors hope to clarify the matter and shed new light on some of the elements of Japanese architecture found in Schindler′s House, including the aspects of sun and light control. This was done through research into original documents in archives in California and with the help of contemporary simulation tools, duly tested by means of on-site measurements. The results show clear similarities between key concepts of Schindler House and descriptions of Japanese architecture. Some of these concepts have been considered essential elements of Schindler architecture and were subsequently reproduced in other houses in California.
著者
浜島 渡 森野 浩
出版者
日本ベントス学会
雑誌
日本ベントス研究会誌 (ISSN:18838898)
巻号頁・発行日
vol.1984, no.26, pp.43-44, 1984-03-31 (Released:2009-08-07)

Growth, survivorship of immature animals and breeding activity in Jesogarrmarus sp, were studied at 9°C, 14°C and 19°C in the laboratory. Growth rates increased with temperatures in isolated condition but decreased in group animals. Initial mortality was highest in 19°C and survivorship was low in group animals than in isolated animals. Breeding was least successful in 19°C in terms of the release of young per female breeding cycle as well as the number of young released per brood. It was concluded that the upper critical temperature for the population of Jesogammarus sp, lay at about 19°C.
著者
冨山 道夫
出版者
日本小児耳鼻咽喉科学会
雑誌
小児耳鼻咽喉科 (ISSN:09195858)
巻号頁・発行日
vol.34, no.1, pp.23-28, 2013 (Released:2013-06-17)
参考文献数
24

伝染性単核球症に対するぺニシリン系抗菌薬(PCs)投与は高率に皮疹を生じるため禁忌である。一方細菌性急性咽頭・扁桃炎の主な起炎菌は A 群 β 溶血性連鎖球菌(A 群溶連菌)で,PCs が第一選択薬とされている。今回 A 群溶連菌感染症を合併した伝染性単核球症の 1 例を経験した。症例は 7 歳女児で咽頭痛,発熱を主訴に受診した。上咽頭,口蓋扁桃に白苔,発赤を認め A 群溶連菌迅速診断陽性であった。自動血球測定装置でリンパ球優位の白血球上昇がみられたため,肝機能検査,Epstein-Barr (EB)ウイルス抗体検査を行うとともに cefditoren pivoxil を投与した。細菌検査では上咽頭,口蓋扁桃より A 群溶連菌が 3+ 検出された。血液検査では肝機能低下,異型リンパ球,EB ウイルス感染を認め伝染性単核球症と診断された。治療後 3 日目に解熱した。A 群溶連菌迅速診断陽性の急性咽頭・扁桃炎に対する抗菌薬選択にあたり,白血球分画を測定する必要があると思われた。
著者
Masahito Katsuki Yasuhiko Matsumori Kenta Kashiwagi Shin Kawamura Akihito Koh
出版者
Societas Neurologica Japonica
雑誌
臨床神経学 (ISSN:0009918X)
巻号頁・発行日
pp.cn-001812, (Released:2023-01-31)
参考文献数
26
被引用文献数
1

Objectives: Tension-type headache (TTH) is the most prevalent type of primary headache disorder. Its acute pharmacotherapy is acetaminophen or non-steroidal anti-inflammatory drugs based on the Japanese Clinical Practice Guideline for Headache Disorders 2021. With Japan’s aging population, however, the number of TTH patients with comorbidities that have been treated by analgesics is increasing. Under this context, it is sometimes difficult to select an acute pharmacotherapy for TTH. Kakkonto, Japanese traditional herbal kampo medicine, is empirically used for TTH. We hypothesized that kakkonto has efficacy for TTH with painful comorbidities. Materials and Methods: We prospectively collected 10 consecutive TTH patients who had already taken analgesics for comorbidities. We prescribed 2.5 g of kakkonto (TJ-1), and patients took it. A numerical rating scale for pain before and 2 hours after kakkonto intake was evaluated. Results: Eight women and 2 men were included. The mean age was 71.0 ± 13.4 years old. Four patients had lower back pain, 2 had lumbar spinal stenosis, 2 had knee pain, 1 had neck pain, and 1 had shoulder myofasciitis. Celecoxib was used for 4 patients, acetaminophen for 3, loxoprofen for 2, and a combination of tramadol and acetaminophen for 1, as routinely used analgesics. The median numerical rating scale statistically improved from the median of 4 to that of 0. There were no side effects of kakkonto. Conclusion: Kakkonto showed efficacy as an acute medication for TTH with comorbidities that have been treated by analgesic.
著者
関本 征史 伊是名 皆人 石坂 真知子 中野 和彦 松井 久実 伊藤 彰英
出版者
日本毒性学会
雑誌
日本毒性学会学術年会 第45回日本毒性学会学術年会
巻号頁・発行日
pp.O-34, 2018 (Released:2018-08-10)

【背景】近年、環境基準が定められていない化学物質による河川の潜在的な汚染が報告されており、ヒトや野生生物に対する生体影響が懸念されている。共同研究者の伊藤らは、天白川(愛知県)や境川(東京都)などの都市部河川において、MRI造影剤に使用される希土類元素ガドリニウム(Gd)の河川中濃度が増加していることを見いだしている(Bull. Chem. Soc. Jpn., 77, 1835(2004)、Chem. Lett., 46, 1327(2017))。本研究では、Gd造影剤の水生生物に対する毒性影響を把握する基礎実験として、水生生物由来培養細胞に対する致死毒性の有無を検討した。【背景】ティラピア肝由来Hepa-T1細胞およびアフリカツメガエルの肝由来A8細胞は理研バイオリソースセンターより入手した。両細胞をそれぞれの培養条件で24時間前培養した後、有害重金属(Cd、Cr、Hg)およびGd無機塩、あるいはGd造影剤(Gd-DOTA、Gd-DTPAおよびGd-DTPA-BMA)を最大濃度100 µMで24時間または72時間曝露し、Alamer Blue Assayにより細胞毒性を評価した。【結果】Hepa-T1細胞に対してHg、CdおよびCrはいずれも強い細胞毒性(生存率20%以下)を示した。一方A8 細胞に対してHgは強い細胞毒性を、Crは弱い細胞毒性(生存率 50%以下)を示したが、Cd は24時間処理では全く毒性を示さなかった。72時間処理では、100 µM Cd 処理によりA8細胞での細胞死が認められた。なお、Gd およびGd造影剤処理による細胞毒性はどちらの細胞株においても観察されなかった。【考察】本研究より、現在の河川中濃度レベルのGd造影剤は細胞死を引き起こさす可能性は小さいものと思われた。また、水生生物由来細胞の間でいくつかの環境汚染重金属の毒性影響が異なることが示された。これは、用いた細胞間での「重金属の取込・排泄」「重金属毒性発現に関わる細胞内因子」の相違に起因することが考えられた。現在、分子レベルでの毒性影響について、遺伝子発現変動を指標とした検討を進めている。