著者
野村 正實
出版者
埼玉大学経済学会
雑誌
社会科学論集 (ISSN:05597056)
巻号頁・発行日
no.143, pp.1-18, 2014-11

After graduating from the Graduate School of Economics at the University of Tokyo in 1980, KAMII Yoshihiko got tenure as lecturer of labor economics at Saitama University, a national university near Tokyo. He was promoted to associate professor in 1983, and to professor in 1994. He was elected to dean of Faculty of Economics in 2002, serving six years. In 2008 he was elected to President of Saitama University and served six years until March 2014.Judging from his career, his life seems to be a typical academic success story, but in reality, it is a long story of severe setback and dramatic comeback. In this essay I examine what his career means to Japan's labor studies and evaluate his contributions to labor research.
著者
野村 俊明
出版者
日本医科大学医学会
雑誌
日本医科大学医学会雑誌 (ISSN:13498975)
巻号頁・発行日
vol.7, no.4, pp.166-168, 2011 (Released:2011-12-22)
参考文献数
14
著者
野村正二郎著
出版者
国土社
巻号頁・発行日
1965
著者
藤田 浩 岡本 公彰 高尾 亜由子 野村 鳴夫 永山 績夫
出版者
日本DDS学会
雑誌
Drug delivery system (ISSN:09135006)
巻号頁・発行日
vol.11, no.3, pp.169-174, 1996-05-10
参考文献数
15

S-1 is an oral form mixture of tegafur (FT) which produces 5-FU, 5-chloro-2, 4-dihydroxypyridine (CDHP) which inhibits 5-FU degradation and oxonic acid (Oxo) which reduces 5-FU toxicities, in a molar ratio of 1 : 0.4 : 1. Pharmacokinetics of S-1 were studied using tumor-bearing animals. Bioavailahility : AUC<SUB>po</SUB>/AUC<SUB>iv</SUB> ratios of FT, CDHP and 5-FU in rabbits were almost 100% with some individual differences, while that of Oxo was 10% or less. The ratio showed a tendency to be higher in fasting animals than in feeding animals, especially in the case of 5-FU (P<0.05). CDHP and Oxo : In tumor-bearing rabbits and mice, CDHP was absorbed well and distributed at high levels in the GI tract and kidney, and detected at moderate levels in the liver, tumor and plasma. The most part of Oxo remained in the GI tract and it was also detected at a high concentration in the kidney, while at low in the liver, tumor and bone marrow. 5-FU following dose escalation of S-1 : S-1 was administered to tumor-bearing rats at doses of 2, 5, 10, 20 mg/kg. AUCs<SUB>0&sim;24h</SUB> of 5-FU were observed at the highest in the tumor in any dosing groups, in order of tumor>bone marrow>spleen>kidney>GI tract>liver and plasma. However, it was noticeable that AUC<SUB>tumor</SUB>/AUC<SUB>plasma</SUB> ratio rather decreased as the escalation of S-1 dose. The reason would be that 5-FU increased non-linearly in the plasma and most normal tissues following the dose escalation of S-1. Based on these data, the optimum dosage of S-1 in humans should be established to maximize the anticancer effects and minimize the adverse reactions.
著者
森 雅彦 野村 裕知
出版者
日経BP社
雑誌
日経ビジネス (ISSN:00290491)
巻号頁・発行日
no.1162, pp.112-115, 2002-10-14

問 民事再生法を適用して倒産した名門工作機械メーカー日立精機の工作機械事業を買収して約1カ月が経ちました。 答 買収契約を締結した9月11日から、日立精機と子会社の社員合わせて800人ほど面接を行い、その半分に当たる420人を子会社の森精機ハイテックの社員として再雇用しました。既に今月1日から営業を開始しており、彼らには存分に働いてもらっています。