著者
ギュヴェン デヴリム C
出版者
東京大学大学院総合文化研究科言語情報科学専攻
雑誌
言語情報科学 (ISSN:13478931)
巻号頁・発行日
vol.9, pp.187-202, 2011-03-01

Oe Kenzaburo's "Applause" ("Kassai", 1958) recounts the story of Natsuo, a university student who is the "male mistress" of Lucien, a foreign diplomat posted in Japan. Natsuo's encounter and "successful" sexual intercourse with Yasuko, who is hired as a maid-prostitute by Lucien gives him hopes about an authentic "commitment" with her. Yet his plan collapses when he learns that she is in fact a prostitute specializing exclusively in homosexual couples, and all was a game planned by Lucien in order for Natsuo to become economically and sexually further dependent upon him. Oe used "sexuality" as a metaphor for articulating politics and power relations; the current political disengagement of Natsuo and the stagnation of the student movement during the suffocating social atmosphere of the late 1950s are translated into a creative discourse of sexuality by adopting images of impotence, sexual dependence and prostitution. Through juxtaposing almost all socio-political and sexual senses of the word "engagement" and a deliberate mistranslation of the French word "engager", Oe attempts to expose the effects of power mechanism of the Eurocentric culture, i.e., "cultural imperialism" on the periphery countries.
著者
Nuno Cortez-Dias Marina C. Costa Pedro Carrilho-Ferreira Doroteia Silva Cláudia Jorge Carina Calisto Teresa Pessoa Susana Robalo Martins João Carvalho de Sousa Pedro Canas da Silva Manuela Fiúza António Nunes Diogo Fausto J. Pinto Francisco J. Enguita
出版者
日本循環器学会
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
vol.80, no.10, pp.2183-2191, 2016-09-23 (Released:2016-09-23)
参考文献数
38
被引用文献数
68

Background:MicroRNAs (miRNAs) are key players in cardiovascular development and disease. However, not only miRNAs of a cardiac origin have a critical role in heart function. Recent studies have demonstrated that miR-122-5p, a hepatic miRNA, increases in the bloodstream during ischemic cardiogenic shock and it is upregulated in the infarcted myocardium. The aim of the present study was to determine the potential of circulating miR-122-5p as a biomarker for early prognostic stratification of ST-segment elevation acute myocardial infarction (STEMI) patients.Methods and Results:One hundred and forty-two consecutive STEMI patients treated with primary angioplasty were included in the study. Serum levels of miR-1-3p, -122-5p, -133a-3p, -133b, -208b-3p and -499a-5p were measured at the time of cardiac catheterization by quantitative polymerase chain reaction and related to in-hospital and long-term outcome. During a follow up of 20.8 months, 9 patients died, 6 had recurrence of myocardial infarction, and 26 patients suffered an adverse cardiovascular event. Event-free survival was significantly worse in patients with a higher miR-122-5p/133b ratio (3rd tertile distribution, above 1.42 Log(10)), having almost a 9-fold higher risk of death or myocardial infarction and a 4-fold higher risk of adverse cardiovascular events.Conclusions:This study showed that the miR-122-5p/133b ratio is a new prognostic biomarker for the early identification of STEMI patients at a higher risk of developing major adverse events after undergoing primary percutaneous coronary intervention. (Circ J 2016; 80: 2183–2191)
著者
Tanaka Takashi Kanatsu-Shinohara Mito Lei Zhenmin Rao C.V. Shinohara Takashi
出版者
Elsevier Inc.
雑誌
Stem Cell Reports (ISSN:22136711)
巻号頁・発行日
vol.7, no.2, pp.279-291, 2016-08-09
被引用文献数
52

精子幹細胞の自己複製を促す新規遺伝子の発見. 京都大学プレスリリース. 2016-08-10.
著者
Maughan Deryck C.
出版者
日経BP社
雑誌
日経ビジネス (ISSN:00290491)
巻号頁・発行日
no.873, pp.70-73, 1997-01-13

米国債不正入札から5年,米証券ソロモン・ブラザーズが復調した。東京支店長から本社会長となったモーン氏は,専門分野で世界のトップ3に入るという目標を掲げる。円の国際化や日本の株式市場活性化には「規制緩和が必要」と指摘,緩和しなければ「円は敗北する」と警告する。最初の1年はまさに「サバイバル」スキャンダル発覚直後は,まさに非常事態でした。
著者
Claire C. CARUSO
出版者
独立行政法人 労働安全衛生総合研究所
雑誌
Industrial Health (ISSN:00198366)
巻号頁・発行日
vol.44, no.4, pp.531-536, 2006 (Released:2006-11-02)
参考文献数
78
被引用文献数
53 128

The paper summarizes research linking long work hours to a wide range of risks to workers, families, employers, and the community. The risks are theorized to stem from less time to recover from work, longer exposure to workplace hazards, and less time to attend to non-work responsibilities. Risks to workers include sleep deprivation, poor recovery from work, decrements in neuro-cognitive and physiological functioning, illnesses, adverse reproductive outcomes, and injuries. Risks to families include delayed marriages and child bearing, and obesity in children. Risks to employers include reduced productivity and increases in workers errors. Mistakes by fatigued workers have broad reaching impacts to the community: medical errors, automobile crashes with other drivers on the road, and industrial disasters that damage the environment.
著者
Nagaya K. Motomura K. Kukk E. Fukuzawa H. Wada S. Tachibana T. Ito Y. Mondal S. Sakai T. Matsunami K. Koga R. Ohmura S. Takahashi Y. Kanno M. Rudenko A. Nicolas C. Liu X.-J. Zhang Y. Chen J. Anand M. Jiang Y. H. Kim D.-E. Tono K. Yabashi M. Kono H. Miron C. Yao M. Ueda K.
出版者
American Physical Society
雑誌
Physical Review X (ISSN:21603308)
巻号頁・発行日
vol.6, no.2, 2016-06-16
被引用文献数
17

X線自由電子レーザーの超短パルスでリボ核酸塩基分子中の電荷と原子の動きを可視化-ヨウ化ウラシルによる放射線増感効果の機構解明. 京都大学プレスリリース. 2016-07-04.