著者
大重 彌吉
出版者
Okayama Medical Association
雑誌
岡山医学会雑誌 (ISSN:00301558)
巻号頁・発行日
vol.66, no.5, pp.933-949, 1954-05-31 (Released:2009-08-24)
参考文献数
17

I have made a report about two villages which may be regarded as random samples of farm villages in mountainious districts, to offer such materials as will help to make accurate statistics in future.Schizophrenia shows a percentage of 0.49 to the population, the corrected frequency being 1.01% (dangerous age 16-40; referred number 2168.0), the percentage of manicdepressive psychosis in 0.04, the corrected frequency 0.12% (dangerous age 21-50; referred number 1710.0) and the percentage of essential epilepsy is 0.11. the corrected frequency 0.17% (dangerous age 21-30; referred number 2922.0).
著者
安部 益文
出版者
Okayama Medical Association
雑誌
岡山医学会雑誌 (ISSN:00301558)
巻号頁・発行日
vol.93, no.9-10, pp.941-949, 1981-10-30 (Released:2009-03-30)
参考文献数
14

マイクロ波は周波数300MHz~30GHzの電波であるが,このマイクロ波の電界に誘電物質をおくと,電波エネルギーは物質に吸収され熱エネルギーに変る.この高周波誘電加熱に立脚して開発された電子レンジが日常の簡易滅菌に如何なる有効性を示すかを検討した.供試微生物はS. aureus, E. coli, Ps. aeruginosa, B. subtilisの芽胞, C. albicans, Echo virus及びHerpes simplexである.これらをガラス及びプラスティク哺乳瓶に定量的に附着させ電子レンジ(2450MHz 500W)で照射した.微生物の大低のものは5~6分,芽胞でも7分で完全死滅した.付着後乾燥状態にした場合はやや長時間を要したが,芽胞やウイルスでも12分では完全死滅した.以上のことから,マイクロ波による滅菌はその局部内部加熱作用が微生物の滅菌に有効に働き,包装状態のままで短時間で行える上に,プラスティク,ゴムなどの容器は損傷されず極めて有用性の高いことが判明した.
著者
前橋 明
出版者
Okayama Medical Association
雑誌
岡山医学会雑誌 (ISSN:00301558)
巻号頁・発行日
vol.102, no.11-12, pp.1229-1239, 1990 (Released:2009-03-30)
参考文献数
15

In order to determine the effects of physical loading on the health status of children who attend swimming classes, subjective and objective changes caused by exercise were studied. In addition, this study also attempts to understand the place of outdoor exercise in daily life and to grasp fundamental problems of health care for children.In my investigation, 43 children exercised in a swimming pool for 75 minutes, and subjective symptoms of fatigue, flicker fusion values, and excretion of uninary protein before and after swimming were analyzed.The results revealed that so-called Group I and III subjective symptoms of fatigue were increased after swimming as compared with before suggesting that physical and nervous symptoms were induced by swimming. However, Group II symptoms, i.e. psychological complaints, were decreased, compared with before swimming.Second, flicker fusion values for the whole sample before and after physical loading were not changed by exercise, though swimming tended to decrease flicker fusion values in boys (p<0.05). On the other hand, the flicker fusion value tended to increase in girls (p<0.05).Third, the excretion of urine per hour was increased (p<0.05) after swimming in an exercise-dependent manner, though the specific gravity of urine significantly decreased (p<0.01).Finally, urinary pH tended to decrease in boys but did not change in girls after swimming, and the concentration of urinary protein was significantly lower after swimming (p<0.01).
著者
中尾 篤典
出版者
岡山医学会
雑誌
岡山医学会雑誌 (ISSN:00301558)
巻号頁・発行日
vol.129, no.1, pp.9-15, 2017-04-03 (Released:2017-05-01)
参考文献数
46
被引用文献数
1 1
著者
中塚 幹也
出版者
岡山医学会
雑誌
岡山医学会雑誌 (ISSN:00301558)
巻号頁・発行日
vol.119, no.1, pp.27-32, 2007-05-01 (Released:2008-07-04)
参考文献数
31
著者
安部 益文
出版者
岡山医学会
雑誌
岡山医学会雑誌 (ISSN:00301558)
巻号頁・発行日
vol.93, no.9, pp.941-949, 1981
被引用文献数
2

マイクロ波は周波数300MHz~30GHzの電波であるが,このマイクロ波の電界に誘電物質をおくと,電波エネルギーは物質に吸収され熱エネルギーに変る.この高周波誘電加熱に立脚して開発された電子レンジが日常の簡易滅菌に如何なる有効性を示すかを検討した.供試微生物はS. aureus, E. coli, Ps. aeruginosa, B. subtilisの芽胞, C. albicans, Echo virus及びHerpes simplexである.これらをガラス及びプラスティク哺乳瓶に定量的に附着させ電子レンジ(2450MHz 500W)で照射した.微生物の大低のものは5~6分,芽胞でも7分で完全死滅した.付着後乾燥状態にした場合はやや長時間を要したが,芽胞やウイルスでも12分では完全死滅した.<br>以上のことから,マイクロ波による滅菌はその局部内部加熱作用が微生物の滅菌に有効に働き,包装状態のままで短時間で行える上に,プラスティク,ゴムなどの容器は損傷されず極めて有用性の高いことが判明した.
著者
山本 太郎
出版者
岡山医学会
雑誌
岡山医学会雑誌 (ISSN:00301558)
巻号頁・発行日
vol.40, no.7, pp.1467-1480, 1928-07-31

Wie schon bekannt, spielen verschiedene Blutdrüsen, insbesondere die Hypophyse und die Schilddrüse, beim Wasserwechsel eine wesentliche Rolle, während die Frage, wie sich die Keimdrüsen, die mit jenen Organen in innigem Zusammenhang stehen, beim Wasserwechsel verhalten, noch nicht sicher aufgeklärt worden ist. Männlichen Kaninchen unter I Jahr. zu verschiedenen Zeiten nach der Kastration, hat also der Verfasser 40cm 0.9%iger Kocosalzlösung pro Kg Körpergewicht in die Ohrvene der einen Seite eingespritzt und hat dann dass Blut in gewissen Zeitabständen aus der Ohrvene der anderen Seite entnommen, um den Hb-Gehalt, die Zahl der roten Blutkörperchen, den Chlorgehalt, das Serumeiweiss und den Blutzucker zu bestimmen. Von der ersten Woche nach der Kastration an kam die Retention des Wassers und des Chlors im Blute allmählich zum Vorschein, und erreichte in der dritten Woche den Höhepunkt, um dann nach und nach abzuklingen. Sie liess sich, wenn auch nur geringfügig, doch durch "Spermatin", d. h. ein Hodenpräparat, erleichtern. Wir können aber die Veränderungen des Wasser- und Chlorwechsels nach der Kastration nicht sofort direkt auf den Ausfall der Keimdrüsenfunktion zurückführen, da wir noch nicht klar genng beurteilen können, ob und wie die Korrelationsstörungen zwischen den verschiedenen inneresekretorischen Drüsen daran teilhaben.
著者
中林 秀和 武田 和久
出版者
岡山医学会
雑誌
岡山医学会雑誌 (ISSN:00301558)
巻号頁・発行日
vol.124, no.3, pp.231-238, 2012-12-03 (Released:2013-01-04)
参考文献数
65
被引用文献数
1 1

高分化型ヒト肝癌由来細胞株“HuH-7”は,1982年にCancer Researchにその樹立を報告した.HuH-7は,当時の岡山大学医学部附属癌源研究施設病理部門(故佐藤二郎教授)の下で樹立し,これまで多くの研究分野で利用され,世界的に有名な肝癌細胞株となっている.本稿では,有用性の高い分化機能を有するヒト肝癌細胞株HuH-7について,肝細胞癌の腫瘍マーカーであるα-fetoprotein(AFP)を中心に,この細胞株を用いた研究分野に関する詳細を紹介する.
著者
大月 三郎 秋山 一文 森本 清
出版者
Okayama Medical Association
雑誌
岡山医学会雑誌 (ISSN:00301558)
巻号頁・発行日
vol.103, no.3, pp.187-196, 1991-06-18 (Released:2009-08-24)
参考文献数
46

Abuse of psychostimulants such as methamphetamine by humans leads to psychotic symptoms which are virtually indistinguishable from those of paranoid schizophrenia. A similar progressive augmentation was observed in locomotion and stereotyped behavior of animals receiving chronic administration of methamphetamine. Thus, such behavioral sensitization or reverse tolerance phenomenon has been well established as an animal model of susceptibility to exacerbation of methamphetamine-induced paranoid psychosis and schizophrenia. On the other hand, kindling refers to a phenomenon whereby a progressively increasing epileptiform discharge emerges after repeated electrical stimulation in a limbic area and finally culminates in a generalized seizure. Kindling has been best characterized as a model of human temporal lobe epilepsy. This review summarizes the studies on reverse tolerance and kindling phenomenon so far conducted in our department. Acute exacerbation following a re-challenge of methamphetamine in the methamphetamine-treated animals is associated with enhancement of dopamine release in the striatum. The pharmacological and electrophysioloical studies of kindling revealed cumulative evidence that excitatory amino acids play an important role in the induction mechanism of kindling, but that the seizure triggering mechanism may be related to collapse of inhibitory gamma-aminobutyric acid function. Further studies are necessary to understand these two important phenomena for psychiatry.
著者
難波 祐三郎
出版者
岡山医学会
雑誌
岡山医学会雑誌 (ISSN:00301558)
巻号頁・発行日
vol.126, no.2, pp.109-115, 2014-08-01 (Released:2014-09-01)
参考文献数
7
著者
吉井 清水
出版者
Okayama Medical Association
雑誌
岡山医学会雑誌 (ISSN:00301558)
巻号頁・発行日
vol.70, no.3, pp.879-903, 1958-03-31 (Released:2009-03-30)
参考文献数
17

1. The author has made researches, in summer, autumn and winter, of the quantitative variation, following the time after death, of the non-protein nitrogen in bones and cartilages, and the anorganic phosphoric, sulphuric and nitric acid in brains, lungs, livers, kidneys and spleens of rabbits.2. Each quantities of the non-protein nitrogen in bones and cartilages increase following the time for a certain period after death. The quantities of the anorganic acids in these five organs increase similarly following the time after death, and then decrease after a certain period.3. The author has proved that the disintegration of dead bodies is more speedy 8-11 times in summer and 3-4 times in autumn than in winter.
著者
青野 要 山本 道夫 飯田 荘介 内海 耕慥
出版者
岡山医学会
雑誌
岡山医学会雑誌 (ISSN:00301558)
巻号頁・発行日
vol.90, no.9-10, pp.1297-1308, 1978-10-30 (Released:2009-08-24)
参考文献数
36
被引用文献数
1

In relation to the mechanism by which hemolysis was induced in radiated human erythrocytes in vitro, several inducements of membrane lipid peroxidation and protective effects of V. E and SOD were investigated. Results obtained were as follows:(1) K+-release from erythrocytes was accelerated by radiation prior to hemolysis. These accelerated hemolysis and K+-release were protected remarkably by V. E and evidently by SOD.(2) Mitochondrial Fe2+ induced and Fe3+-O2 generating system - ADP induced lipid peroxidation, and microsomal O2 generating system - induced lipid peroxidation were also protected by V. E and SOD.(3) Radiation of X-ray or 60Co γ-ray accelerated lipid peroxidation of liver homogenate, microsome and liposome. Some of these accelerated lipid peroxidations were protected effectively by V. E and SOD.These results suggest that O2 and/or OH·generation by radiation induces of membrane lipid peroxidation, which leads deterioration of membrane resulting in the change of ion permeability and then hemolysis.
著者
北川 尚広
出版者
岡山医学会
雑誌
岡山医学会雑誌 (ISSN:00301558)
巻号頁・発行日
vol.106, no.3-4, pp.359-377, 1994 (Released:2009-03-30)
参考文献数
14

Some parameters are altered by the magnetic field strength, and a different image is obtained with the same parameter, because of the altered magnetic field strength. The contrast effect by contrast material for MRI (Gd-DTPA) differs with the magnetic field strength. We studied the T1 and T2 relaxation time of various solutions and relaxivity of Gd-DTPA with a low (0.2tesla) and high (1.5tesla) magnetic field machine, and considered the optimal sequence. T1 relaxation time is prolonged 2040% at 1.5T compared with 0.2T. Using MnCl2, the relaxivity of Gd-DTPA is 3.66.8mmo1-1 sec-11. Using albumin, the relaxivity is 5.812.1mmo1-1 sec-11. This difference is due to the difference in molecular size. T1 contrast, T2 contrast and signal intensity are weak with the low magnetic field machine. The signal intensity must be strengthened by changing some parameters (acquisitions, matrix, band width, etc.), and a shorter TR is suitable for T1 weighted images with a low magnetic field machine. For postcontrast T1 weighted images, shorter TR and shorter TE are useful to obtain a good contrast. More contrast material, and a longer TE is suitable for T2 weighted images wiht a low magnetic field machine.