5 0 0 0 OA エキソソームによる粘膜免疫賦活機構の解明
免疫関連タンパク質のDPP IV、IgA、唾液タンパク質のムチン5B、口腔内細菌由来のLPSは、ヒト唾液由来エキソソーム表面に緩く相互作用している。これら表面分子のうちムチン5Bは消化酵素で分解され、IgAおよびLPSの大部分はゲルろ過クロマトグラフィーによりエキソソーム表面から剥がれるが、一部は強固に結合していた。表面分子を除去したエキソソームはマクロファージからのNO産生を増強させた。本作用には膜貫通タンパク質であるDPP IVがLPSと協調している可能性を見いだした。唾液由来の粘膜免疫エキソソームは口腔内では免疫系の過剰な活性化を抑制し、消化管内では免疫系の活性化に関与する可能性がある。
- 著者
- 江良 智美
- 出版者
- 帝京平成大学
- 雑誌
- 帝京平成大学紀要 = Journal of Teikyo Heisei University (ISSN:13415182)
- 巻号頁・発行日
- vol.32, pp.27-34, 2021-03
Let's Go Young , which held a prominent place in the history of popular music from the 1970s to the 1980s, provides a valuable record for learning about the trends of the times, from the clothing worn by the different weekly guest performers, hosts, and regular performers, and from their communication with the audience. The relationship between fashion and music in television media runs deep, and it could be argued that fashionable outfits on teen-oriented programs led to an understanding of the reception of new music. This study analyzes the expression methods in the presentation of foreign music as cultural knowledge on the third season of Let's Go Young , focusing on the stylistic expression demonstrated by the performers' outfits.
3 0 0 0 IR 昭和20年代の小学校の授業における鬼遊びの扱われ方
- 著者
- 鈴木 邦明
- 出版者
- 帝京平成大学
- 雑誌
- 帝京平成大学紀要 (ISSN:13415182)
- 巻号頁・発行日
- no.32, pp.183-188,
The current study has focused on elementary school curriculum guideline during a decade from 1945 when game of tag was positively adopted as a class at school. Objective was to analyze how the game of tag was handled and clarify educational system and social situation back then. A characteristic of game of tag is that players move their bodies in various ways. Previous studies have found that the game helps improve such abilities as stamina, running, and agility. Also, the game has been found to be good for not only physical aspects but also children's sociality and cooperation. As a result of the research, it has been proved that ratio of game of tag using certain tools was lower in the school curriculum guideline back then compared with that in 2017. It is believed to be associated with lack of supplies after the war. The game is also characterized as being playable without any tools. Furthermore, its rule is so flexible that it can be played depending on conditions. Those characteristics may have led to the results this time.
- 著者
- 小舘 英實 小野 諭
- 出版者
- 帝京平成大学
- 雑誌
- 帝京平成大学紀要 (ISSN:13415182)
- 巻号頁・発行日
- vol.12, no.1, pp.13-26, 2000-06-30
A tournament-type match table has been widely employed to decide the winner of games. In the case of a balanced table, participants can win after the same number of games, or one time less, depending on the number of participants. Spectators want to watch good exciting games, especially in semi-finals and the final, so powerful participants are given seeded rights in the table. On the other hand, powerful participants may, sometimes, expect to win after one time less or even less. Therefore, there may be two kinds of seeded rights : nominal and substantial. The nominally seeded players have to play the same number of games or one time less and the substantially seeded do one time less or even less. We succeeded in generating a good table by unbalanced partitions, under the strict condition of the 2-3-4 trees structure as one of balanced data structures.
2 0 0 0 OA 立位股関節回旋角度並びに荷重動揺軌跡測定による運動技能評価システムの確立
本研究の目的は、回旋角度測定器付き荷重動揺計を用いた立位股関節回旋角度測定法を普及させ、この装置の自動運動中に得られる股関節回旋角度および荷重動揺軌跡から姿勢制御力や身体運動能の評価システムを確立することである。この評価システムの意義は、動的荷重動揺軌跡の形状や角度変化に着目し、動作の精度や運動能の評価を容易にしたところにある。平成24~27年度にトップアスリートから一般人まで1000名近くのデータを得た。軌跡図の形状や回旋角度の変化を精査した結果、下肢動作の左右差(一側優位性)やスポーツ種目ごとの特性を見出した。動作の精度に影響を及ぼす疲労や開脚幅の広がり等の諸要因について検討を加えた。
2 0 0 0 IR 東京都内におけるスクールソーシャルワーカー配置状況
- 著者
- 米川 和雄
- 出版者
- 帝京平成大学
- 雑誌
- 帝京平成大学紀要 = Journal of Teikyo Heisei University (ISSN:13415182)
- 巻号頁・発行日
- vol.25, pp.79-86, 2014-03
The purpose of this study is to clarify the situation of school social worker (SSWr) assignment in the boards of education in Tokyo. As a result, cooperation was obtained from 35 municipalities for the survey; I reported on 36 municipalities through adding some of the past survey results for 1 municipality. (1) SSWr utilization project-related matters: The main part of the business budget framework was <SSWr utilization project in Tokyo (28 municipalities: 77.8%; this project is oriented Tokyo metropolis spending)<. SSWr support was centered on elementary and junior high schools. The assignment form of SSWrs was almost all conducted by dispatching SSWrs upon schools' request. The system of SSWr support was first introduced in 2 wards in Tokyo in 2007, and implemented in 19 cities, 16 wards and 1 town by 2013. Implementation of worker support continued increasing in cities and in wards. Furthermore, approximately 19.4 % of the municipalities were planning to increase SSWr utilization in the future. (2) Employment situation: the number of SSWrs utilized was minimum 1 person, maximum 8 people, and 2.31±1.49 people on the average and standard deviation. As to the ratio of social workers or psychiatric social workers, 61 within 83 SSWrs (73% or more) had the national qualification. On the contrary, workers were neither social workers nor psychiatric social workers in 6 municipalities (16.7%). As for type of employment, approximately a half of the municipalities had employed workers as part-timers, and other types of employment (temporary, consignment, remuneration per activity) accounted for an almost equal proportion each. The average number of work (support) hours of all the workers through the year was 1029.29 (minimum 160 hours, maximum 1536 hours). Converted into an hourly rate, the average wage of all the modes of wage payment (salary, daily wage, hourly wage) was 2,423 yen (minimum 1,466 yen, maximum 5,800 yen). In addition, the total annual number of SSWr support hours per student in each municipality was 0.22 on the average. Furthermore, 18 municipalities (47.2%) provided social insurance (medical insurance & labor insurance & annuity insurance, or only labor insurance), and 21 municipalities (58.3%) provided transportation costs. (3) The presence of a supervisor: 15 municipalities (41.7%) were utilizing supervisors, and the frequency of the use of supervisors varied from 3 times a year to 16 days a month. As seen from the above results, it is conceivable that social action for improvements in SSWr utilization and treatment is required of municipalities with few or non opportunities for SSWrs, and that it is necessary to continue conducting surveys.
2 0 0 0 IR 保育者養成校における子育て支援の実践と課題
- 著者
- 齊藤 美代子 サイトウ ミヨコ Saito Miyoko 遠藤 純子 エンドウ ジュンコ Endo Junko 園川 緑 ソノカワ ミドリ Sonokawa Midori 韓 仁愛 ハン インエイ Han Inae
- 出版者
- 帝京平成大学
- 雑誌
- 帝京平成大学紀要 (ISSN:13415182)
- 巻号頁・発行日
- vol.26, no.2, 2015-03
On the basis of the past achievements of our child-rearing support program, this study aims to identify educational issues in the childcare worker/teacher training school. In this paper, we have compiled a report on "Puri-Puri Kids Univ<, a child-rearing support program which simultaneously provides our students with training opportunities and on-the-job training (OJT). Also, we investigated current childraising views, child-support programs conducted by other universities and analyzed relevant literature. For the further development of our curriculum, we discussed how we can systematically place a training framework for students within the curriculum which allows them to develop knowledge and skills accumulated through practice in the child-support program during the four-year university education. As a result, the students are thus able to step up efforts to promote better understanding of their discipline, Early Childhood Education and Care.
2 0 0 0 IR 我が国の教育分野における「反省的実践家」の研究動向について--教師の資質再考に向けて
- 著者
- 山際 悟史 奥井 智一朗
- 出版者
- 帝京平成大学
- 雑誌
- 帝京平成大学紀要 (ISSN:13415182)
- 巻号頁・発行日
- vol.22, no.1, pp.35-43, 2011-03
The purpose of the present study is to choose a position on the research trend of <reflective practitioner< in the field of education in our country, and to study the issues associated with the teaching quality for the future. First, research papers with the keyword <reflective practitioner< in education were collected and then the classification based on theoretical or practical research was brought under review. As a result, the research showed that teaching quality was not able to choose between a <reflective practitioner< or <technical expert.< In the end, <Reflection-In-Action< was more effective if the reflection was taken in social context. In addition, the study raised the need for the integration of previous findings, based not only on the debates on <reflective< or <technical< but also on a conceptual level of <belief< and <collegiality<.
2 0 0 0 OA アミノペプチダーゼの動脈硬化症への関与
小胞体アミノペプチダーゼ(ERAP1)はインターフェロン(IFN)-γ およびリポ多糖(LPS)処理によりマクロファージから分泌される。このことは、分泌されたERAP1が血液中の血管作動性物質に作用し、血圧を調節している可能性を示している。ERAP1の分泌機構を検討した結果、IFN-γ およびLPS処理により発現誘導されるIFN-β等のサイトカインが細胞内カルシウム濃度を上昇させることが重要であることが示された。また分泌されたERAP1がアンジオテンシンII などN-末端にアルギニンを有するペプチドに作用し、一酸化窒素を産生することで血圧調節に関与しうることも示された。
- 著者
- 宮澤 淳一
- 出版者
- 帝京平成大学
- 雑誌
- 帝京平成大学紀要 (ISSN:13415182)
- 巻号頁・発行日
- vol.7, no.2, pp.7-14, 1995-10-31
David Young's Glenn (1992) is a play about the Canadian pianist Glenn Gould (1932-82). There are four characters in the play, which portray the eras of Gould's fifty-year life and his thoughts: Prodigy (6-22), Performer (22-31), Perfectionist (31-48), and Puritan (48-50). These characters act and symphonize their voices in the framework of J.S.Bach's The Goldberg Variations according to the voicing and structure of the music. The use of the framework (the aria, 30 variations and the aria da capo) is a successful device of transfering a musical form into a literary form which is independent of the time-space conventions of the theatre. The play also employs successfully the compositional technique named "contrapuntal radio," which overlaps parallel dialogue and makes coincidental conjunction between voices, because it makes the four Goulds disguise other theatrical Gould-like personae who enliven the inter- actions. For all the complicated plot, the play can be analized clearly if one realizes that the crucial hero is Puritan: the plot is the journey of Puritan who goes back through the whole of Gould's life. The recomposed figure of Glenn Gould in the play is a typical Canadian according to the model of Canadian identity in Margaret Atwood's Survival (1972). Glenn Gould was a man of escape who fled from the "South" to the "North" in order to survive himself, but happened to be a hero in the world as well as in Canada, and is by definition a Canadian anti-hero.
- 著者
- 隈 久雄 高野 香子 萩原 正浩 渡辺 泉
- 出版者
- 帝京平成大学
- 雑誌
- 帝京平成大学紀要 (ISSN:13415182)
- 巻号頁・発行日
- vol.9, no.2, pp.25-32, 1997-12-28
病院情報システムのアーキテクチャとしては, 分散システムが適しているが, 集中システムよりも複雑なために, 保守や拡張性に問題が生じる可能性が高い。オブジェクト指向は, 各オブジェクトがプロセスの中で独立に動作し得る概念であり, 論理的な概念によって分散システムをとらえる仮想分散システムの構築に適している。本紀要第8巻第2号において, 病院の各部門情報システムは, 他部門システムからの自律性が尊重され, 医学の進歩に合わせて, 常に改良・拡張できるフレキシビリティに富んだシステムであることが必要であると論じたが, 本号では, 上記の問題に対する具体的な解決策として, 自律分散型総合病院情報システムのシステム設計にオブジェクト指向によるシステム設計法を応用することを提案し, ADITHISプロトタイプのシステム分析に適用した結果を報告している。
1 0 0 0 OA 地域コミュニティにおける犬の飼い主たちの社会関係
1 0 0 0 IR 新羅・花郎徒衆の忠と薩摩武士の忠の比較検討 : 古代中国思想に見る四つの忠を媒介として
- 著者
- 西中 研二
- 出版者
- 帝京平成大学
- 雑誌
- 帝京平成大学紀要 (ISSN:13415182)
- 巻号頁・発行日
- vol.23, no.1, pp.109-120, 2012-03
In order to study the loyalty that is the foundation of the Bushido spirit of Japan and Chinaand Korea. It is important to make a basis for comparing the loyalty of each country. At first I found the origin of the concept of the loyalty in the Analects of Confucius. And It was named "loyalty of Kijin". As a result of having arranged the loyalty written in documents except the Analects of Confucius, It was classified below the three parts. (1) Loyalty of Tensei, (2) Loyalty of Gigo, (3) Loyalty of Keigo. And the loyalty of the Satsuma samurai was compared with the loyalty of the Silla samurai using these four loyalty.
1 0 0 0 骨格筋における性ホルモン産生
本研究では,性ホルモンの合成組織として骨格筋に着目し,その合成経路が運動により亢進することにより,性ホルモン合成の亢進に寄与するという仮説を立証することを目的とする.上記の研究課題を明らかにするために,骨格筋における性ホルモン合成酵素の発現の有無と局所性ホルモン代謝動態について検討した(研究課題I).さらに,運動による骨格筋内の性ホルモン産生経路を明らかにするために,運動が骨格筋内の性ホルモン合成酵素に及ぼす影響とその性差について検討した(研究課題II).その結果,骨格筋における性ホルモン産生機序に着目し,骨格筋内の性ホルモン合成酵素の遺伝子・タンパク発現が存在することを確認し,骨格筋には性ホルモン代謝経路が存在し,局所にて性ホルモンを産生する器官となりうる可能性を明らかにした(研究課題I).また,骨格筋内の性ホルモン合成酵素の遺伝子・タンパク発現には性差があり,運動刺激に対するそれらの発現応答にも性差があるという結果を得たことから(研究課題II),運動による骨格筋の適応機序に局所の性ホレモン代謝が関与している可能性が示された.それゆえ,運動による性ホルモン作用は,内分泌経路の他に,末梢組織(骨格筋)における局所の性ホルモン産生が重要な役割を果たしている可能性が示された.
1 0 0 0 IR 韓国の野球伝来におけるメディアと日本留学生が果たした役割について
- 著者
- 朴 南圭
- 出版者
- 帝京平成大学
- 雑誌
- 帝京平成大学紀要 (ISSN:13415182)
- 巻号頁・発行日
- no.32, pp.107-112,
Korean baseball game began in 1905 by Gillette, an American missionary at that time. In Korea after colonial liberation, it was difficult to maintain the educational system due to the absence of personnel at many schools. There were also new moves in part, but they had no financial ability or skills to move the whole system. Many US military officers who studied in Japan were appointed during the US military rule that began soon. Military authorities attempted to introduce universities and non-Japanese American education systems to Korea. However, overall reform has not been reached due to lack of management skills and know-how. The education system in the United States will be torn down by the
1 0 0 0 昭和20年代の小学校の授業における鬼遊びの扱われ方
- 著者
- 鈴木 邦明
- 出版者
- 帝京平成大学
- 雑誌
- 帝京平成大学紀要 = Journal of Teikyo Heisei University (ISSN:13415182)
- 巻号頁・発行日
- vol.32, pp.183-188, 2021-03
1 0 0 0 IR 企業内教育における宗教的事項の検討
- 著者
- 黒崎 征佑
- 出版者
- 帝京平成大学
- 雑誌
- 帝京平成大学紀要 (ISSN:13415182)
- 巻号頁・発行日
- vol.10, no.2, pp.35-49, 1998-12
New face and executive educations are carried out as a plan of TWI in recent years. These are almost done for a week or a few months. Some industries have a plan to do it in religious places, for example, the temple of the Zen. Why do Japanese, not American and English, companies make such a choice? But it gradually decreases of late. Why so?
1 0 0 0 IR 『易』学六十四卦から形成されるブール関数について
- 著者
- 吉岡 剛志 中村 昌彦
- 出版者
- 帝京平成大学
- 雑誌
- 帝京平成大学紀要 (ISSN:13415182)
- 巻号頁・発行日
- no.30, pp.107-112,
The Fu xi Liu shi si gua fang wei tu, which is continuously digested the transition of Gua, was associated with binary system by G. W. Leibniz. And we cleared the mechanism by which Liu shi si gua is generated from Kun, which is considered to be the root of all things, was systematized by the binary system, in addition, the process that a new Gua is generated by the transition of Yi was systematized by symbolic notation. Here, although the xue Liu shi si gua have discussed by the use of binary system, it is not clear why the xue Liu shi si gua is discussed by binary system. In this paper, in order to examine the meaning of discussing the xue Liu shi si gua by binary system, we examine how to discuss it by Boolean algebra, and furthermore, discussed Boolean function formed from the Yi xue Liu shi si gua. binary system, it is not clear why the xue Liu shi si gua is discussed by binary system. In this paper, in order to examine the meaning of discussing the xue Liu shi si gua by binary system, we examine how to discuss it by Boolean algebra, and furthermore, discussed Boolean function formed from the Yi xue Liu shi si gua.
1 0 0 0 OA 中心体複製ライセンシング機構におけるセパレースおよびその基質蛋白質の機能解析
中心体は分裂期に双極紡錘体を形成して染色体の均等分配に重要な役割を果たす。そのために中心体の複製は細胞周期につき1回だけ、細胞分裂を経た後に開始できるというライセンシング制御が想定されている。その分子機構は未解明であり、染色体分離に関わるタンパク質分解酵素セパレースが必要であることは知られていたがその基質も不明であった。本研究によって、中心体タンパク質kendrinが中心体におけるセパレースの重要な新規基質であり、分裂期におけるkendrinの限定分解とそれによる中心体からの解離が、次の中心体複製開始すなわちライセンシング機構に必要であることを世界で初めて明らかにした。
1 0 0 0 OA 前十字靱帯損傷に対する内側ハムストリングス集中的トレーニングの予防効果
前十字靭帯(ACL)損傷の予防方法を開発することを目的として、筋活動とACL損傷リスクとの関連性を検討した。接地直前50msにおいてつま先接地(FFS)は踵接地(RFS)に比べて腓腹筋(GL)、半腱様筋(ST)、大腿二頭筋(BF)の筋活動量が有意に大きかった。また、接地直後50msではFFSはRFSに比べてBFとGLの筋活動量が大きく、前脛骨筋の活動量が小さかった。このことからFFSによる動作では、接地前後のハムストリングスの筋活動が高く働くことが示唆され、FFSによるカッティング動作はRFSによるカッティング動作に比べ、ACL損傷リスクの低いカッティング動作であることが明らかとなった。