著者
藤野 篤哉 飛田 敏光 中川 久美子
出版者
The Institute of Electrical Engineers of Japan
雑誌
電気学会論文誌D(産業応用部門誌) (ISSN:09136339)
巻号頁・発行日
vol.117, no.7, pp.815-822, 1997-06-20 (Released:2008-12-19)
参考文献数
9
被引用文献数
4 1

With a view point of space factor in large-scale buildings, this paper first overviews several mass transportation systems and compares their characteristics. Then a loop-type independent-driven multiple-cage elevator system and its high-efficient control method are proposed, The multiple-cage elevator system can reduce its shaft space as half as that of normal elevator system. Computer simulations show the proposed control method can improve waiting time and round trip time, and restrain needless stops. The loop-type multiple-cage elevator system may be feasible for the third transportation system which fills the gap between elevators and escalators in the near future.
著者
丘 光明 加島 淳一郎
出版者
日本計量史学会
雑誌
計量史研究 (ISSN:02867214)
巻号頁・発行日
vol.22, no.1, pp.77-96, 2000
被引用文献数
1
著者
松浦 芙佐子
出版者
岡山商科大学
雑誌
岡山商大論叢 (ISSN:02868652)
巻号頁・発行日
vol.45, no.1, pp.73-97, 2009-06-25
著者
大西 正光 村上 武士 Wu Peiwei 小林 潔司
出版者
公益社団法人 土木学会
雑誌
土木学会論文集D3(土木計画学) (ISSN:21856540)
巻号頁・発行日
vol.73, no.5, pp.I_309-I_322, 2017 (Released:2017-12-27)
参考文献数
21
被引用文献数
1

水道コンセッション事業の経済的価値は,主に水道料金及び水道の接続数(普及率)に依存する.政府が契約条件として望ましい水道料金及び接続数を設定するためには,民間事業者が有する技術に関する情報を有しておく必要がある.政府が技術に関する十分な情報を有していない場合には,技術提案型入札が適用される場合も少なくない.本研究では,技術提案型入札の下での最低単価落札方式と最大接続数落札方式という2つの落札方式の経済的帰結を理論的に分析する.さらに,水道コンセッション事業では,しばしば事後的に初期契約の見直しが行われることを指摘する.その上で,事業者の戦略的ホールドアップ行動の帰結を分析し,各落札方式の得失について考察する.
著者
大島 富朗
出版者
上智大学
雑誌
上智大学国文学論集 (ISSN:02880210)
巻号頁・発行日
vol.26, pp.213-258, 1993-01-16

1 0 0 0 LIFE-TEXT

著者
坂本龍一 高谷史郎著
出版者
NTT出版
巻号頁・発行日
2010
著者
Fujimoto A Tsurumi K Kawada R Murao T Takeuchi H Murai T Takahashi H
出版者
Springer Nature
雑誌
Translational Psychiatry (ISSN:21583188)
巻号頁・発行日
vol.7, 2017-04-04
被引用文献数
17

ギャンブル依存症の神経メカニズム --前頭葉の一部の活動や結合の低下でリスクの取り方の柔軟性に障害--. 京都大学プレスリリース. 2017-04-05.Gambling disorder (GD) is often considered as a problem of trait-like risk preference. However, the symptoms of GD cannot be fully understood by this trait view. In the present study, we hypothesized that GD patients also had problem with a flexible control of risk attitude (state-dependent strategy optimization), and aimed to investigate the mechanisms underlying abnormal risk-taking of GD. To address this issue, we tested GD patients without comorbidity (GD group: n=21) and age-matched healthy control participants (HC group: n=29) in a multi-step gambling task, in which participants needed to clear 'block quota' (required units to clear a block, 1000–7000 units) in 20 choices, and conducted a task-functional magnetic resonance imaging (fMRI) experiment. Behavioral analysis indeed revealed a less flexible risk-attitude change in the GD group; the GD group failed to avoid risky choice in a specific quota range (low-quota condition), in which risky strategy was not optimal to solve the quota. Accordingly, fMRI analysis highlighted diminished functioning of the dorsolateral prefrontal cortex (dlPFC), which has been heavily implicated in cognitive flexibility. To our knowledge, the present study provided the first empirical evidence of a deficit of state-dependent strategy optimization in GD. Focusing on flexible control of risk attitude under quota may contribute to a better understanding of the psychopathology of GDs.
著者
Eiichiro NAITO Yasuto YOSHIDA Satoru KUNIHIRO Kumiko MAKINO Kohei KASAHARA Yuu KOUNOSHI Masanori AIDA Ryotaro HOSHI Osamu WATANABE Tomoki IGARASHI Kouji MIYAZAKI Hideki ITO
出版者
BMFH Press
雑誌
Bioscience of Microbiota, Food and Health (ISSN:21863342)
巻号頁・発行日
vol.37, no.1, pp.9-18, 2018 (Released:2018-01-27)
参考文献数
36
被引用文献数
38

An obesity-related prediabetic state is characterised by metabolic abnormalities such as post-glucose load hyperglycaemia and dyslipidaemia and consequently increases the risk for type 2 diabetes and cardiovascular disease. This study aimed to investigate the effects of Lactobacillus casei strain Shirota (LcS) on metabolic abnormalities in obese prediabetic subjects in a randomised, double-blind, placebo-controlled trial. Herein, 100 obese subjects (body mass index ≥25), who had moderate post-load hyperglycaemia (1-hr post-load plasma glucose (PG) levels ≥180 mg/dl during the oral glucose tolerance test), consumed LcS-fermented milk or placebo milk daily for 8 weeks. The post-load PG and fasting blood markers were evaluated. Although post-load PG levels were not significantly different between the groups, 1-hr post-load PG, glycoalbumin, and HbA1c levels decreased at 8 weeks compared with the baseline levels only in the LcS group (p=0.036, p=0.002, and p=0.006, respectively). The reduction in glycoalbumin levels was statistically significantly greater in the LcS group than in the placebo group (p=0.030). Stratified analyses revealed significantly improved 1-hr post-load PG and glycoalbumin levels in the LcS group compared with the placebo group among subjects with severe glucose intolerance (2-hr post-load PG levels higher than the median at baseline; p=0.036 and p=0.034, respectively). In terms of lipidic outcomes, total, low-density lipoprotein, and non-high-density lipoprotein cholesterol levels were significantly lower in the LcS group than in the placebo group (p=0.023, p=0.022, and p=0.008, respectively). These findings suggest that LcS may favourably affect metabolic abnormalities in obese prediabetic subjects, though the effects on glycaemic control may be limited.
著者
Hiroshi ASHIGAI Yuta KOMANO Guanying WANG Yasuji KAWACHI Kazuko SUNAGA Reiko YAMAMOTO Ryoji TAKATA Mika MIYAKE Takaaki YANAI
出版者
BMFH Press
雑誌
Bioscience of Microbiota, Food and Health (ISSN:21863342)
巻号頁・発行日
vol.37, no.1, pp.19-24, 2018 (Released:2018-01-27)
参考文献数
25
被引用文献数
10

Atopic dermatitis (AD) is a chronic inflammatory skin disease that causes dry skin and functional disruption of the skin barrier. AD is often accompanied by allergic inflammation. AD patient suffer from heavy itching, and their quality of life is severely affected. Some pharmaceuticals for AD have some side effects such as skin atrophy. So it is necessary to develop mild solutions such as food ingredients without side effects. There are various causes of AD. It is especially induced by immunological imbalances such as IFN-γ reduction. IFN-γ has an important role in regulating IgE, which can cause an allergy reaction. NC/Nga mice develop AD and IgE hyperproduction. In a previous study, we revealed that administration of polysaccharide from black currant (R. nigrum) has an effect on immunomodulation. It induces IFN-γ production from myeloid dendritic cells. We named this polysaccharide cassis polysaccharide (CAPS). In this report, we studied the effect of administering CAPS on atopic dermatitis in NC/Nga mice. Thirty NC/Nga mice that developed symptoms of atopic dermatitis were used. We divided them into three groups (control, CAPS administration 12 mg/kg/day, CAPS administration 60 mg/kg/day). For 4 weeks, we evaluated clinical score, serum IgE levels, gene expression of spleen, and skin pathology. We revealed that CAPS administration improves atopic dermatitis symptoms. We also found that CAPS administration suppresses IgE hyperproduction and induces IFN-γ gene transcription in the spleen. Finally, we confirmed that CAPS administration suppresses mast cell migration to epidermal skin. These results indicated that CAPS has an effect on AD.