著者
Ki-Woong PARK Sung Hoon BAEK
出版者
The Institute of Electronics, Information and Communication Engineers
雑誌
IEICE Transactions on Information and Systems (ISSN:09168532)
巻号頁・発行日
vol.E100.D, no.10, pp.2348-2356, 2017-10-01 (Released:2017-10-01)
参考文献数
24
被引用文献数
1

Emerging digital payment services, also known as FinTech, have enabled various types of advanced payment transactions (such as Google Wallet, Apple Pay, Samsung Pay, etc.). However, offline peer-to-peer cash transactions still make up about 25.6% of the overall financial transactions in everyday life. By investigating existing online and offline payment systems, we identify three key challenges for building a digital cash transaction system with core features of the offline cash transactions: self-verifiability of digital cash; user anonymity; atomic cash transfer for double spending/depositing protection. In this paper, we propose OPERA, an offline peer-to-peer digital cash transaction system that addresses the three challenges. It newly introduces a concept of ‘one-time-readable memory(ORM)’ and ‘digital token’ which is a unit of self-verifiable digital cash. The one-time readability from ORM and three-stage token exchange protocol enable OPERA to provide uniqueness to digital cash and to allow a complete offline digital payment. OPERA devices are enhanced with TCPA technology to ensure the integrity of the physical device package. To evaluate the feasibility and resilience of the OPERA design, we built a prototype on a customized embedded board.
著者
Akihiro Aoyama Minako Yamaoka-Tojo Shinichi Obara Erika Shimizu Kazuhiro Fujiyoshi Chiharu Noda Atsuhiko Matsunaga Junya Ako
出版者
International Heart Journal Association
雑誌
International Heart Journal (ISSN:13492365)
巻号頁・発行日
vol.60, no.4, pp.854-861, 2019-07-30 (Released:2019-07-27)
参考文献数
45
被引用文献数
4 15

The aim of this single-arm pilot study was to determine the effects of whole-body vibration training (WBVT) on endothelial function in elderly patients with cardiovascular diseases, as well as its safety. A total of 20 elderly patients with stable cardiovascular diseases underwent WBVT, which consisted of five static resistance training exercises (squats, wide stance squats, toe-stands, squats + band, and front lunges). The parameters of WBVT included vertical vibrations, 30 Hz frequency, and a 3-mm peak-to-peak amplitude. Each vibration session lasted 30 seconds, with 120 seconds of rest between sessions. Before and after WBVT, the reactive hyperemia peripheral arterial tonometry index (RH-PAT index) and transcutaneous oxygen pressure (tcPO2) were recorded as a measure of endothelial function and peripheral blood circulation. Systolic blood pressure, diastolic blood pressure, heart rate, and arterial oxygen saturation of pulse oximetry (SpO2) were measured at each rest interval as well as before and after WBVT. All patients completed our WBVT protocol without adverse events. The RH-PAT index significantly increased following WBVT (1.42 to 2.06, P < 0.001). There were no significant changes in heart rate (P = 0.777), systolic blood pressure (P = 0.183), diastolic blood pressure (P = 0.925), or SpO2 (P = 0.248) during WBVT. In conclusion, we demonstrated the acute effects of WBVT on endothelial function, with no reports of adverse events. These findings support the need for further randomized controlled studies to investigate the long-term effects of WBVT.
著者
Jamsransuren Dulamjav Yoshii Kentaro Kariwa Hiroaki Asakawa Mitsuhiko Okuda Kei Fujii Kei Fukumoto Shinya Umemiya-Shirafuji Rika Sasaki Motoki Matsumoto Kotaro Yamaguchi Emi Ogawa Haruko Imai Kunitoshi
出版者
Faculty of Veterinary Medicine, Hokkaido University
雑誌
Japanese Journal of Veterinary Research (ISSN:00471917)
巻号頁・発行日
vol.67, no.2, pp.163-172, 2019-05

The first human case of tick-borne encephalitis (TBE) in Japan was recorded in southern Hokkaido in 1993 and was followed by four further cases in southern, central, and northern Hokkaido during 2016-2018. However, the distribution of TBE virus (TBEV) foci in Japan is unclear. Therefore, here, we serologically examined raccoons (Procyon lotor), sika deer (Cervus nippon), and wild boars (Sus scrofa) as sentinels of TBEV infection in Hokkaido and in Fukushima and Tochigi Prefectures in Honshu. A total of 1,649 serum samples collected between 2003 and 2018 were screened by enzyme-linked immunosorbent assay using subviral particles and confirmed using the virus neutralization test. In raccoons, the seroprevalence of TBEV was 5.9% (39/662 samples) in central Hokkaido in 2003-2005 and 0.8% (3/368 samples) in eastern Hokkaido in 2010-2018, revealing the presence of TBEV foci in these areas. In addition, 0.5% (2/414) of deer sampled in eastern Hokkaido in 2010-2017 and 2.4% (1/42) of deer sampled in Tochigi Prefecture in 2016-2018 were seropositive. On Honshu, seropositive rodents have previously been detected only in Shimane Prefecture. Therefore, the detection of seropositive animals in Tochigi Prefecture may indicate the widespread distribution of TBEV foci throughout Japan. TBEV and viral genes were not detected in 507 ticks collected in the same area of eastern Hokkaido where seropositive animals were found, reemphasizing the value of using serological examination of wild animals as a tool for revealing unknown TBE risk areas. Our findings also indicate that raccoons may be particularly useful sentinels.
著者
Yuri Yaguchi-Tanaka Takahiro Tabuchi
出版者
Japan Epidemiological Association
雑誌
Journal of Epidemiology (ISSN:09175040)
巻号頁・発行日
vol.31, no.7, pp.417-425, 2021-07-05 (Released:2021-07-05)
参考文献数
34
被引用文献数
2 8

Background: Few longitudinal studies have examined the association between skipping breakfast and overweight/obesity in pre-elementary school children. Furthermore, this association may differ between boys and girls. The main objective of this study was to assess whether skipping breakfast in early childhood was associated with later incidence of overweight/obesity, with stratification by gender, using data on children aged 2.5 to 13 years old in The Longitudinal Survey of Newborns in the 21st century.Methods: We examined the associations between skipping breakfast at 2.5 years old and overweight/obesity at 2.5 (n = 34,649), 4.5 (n = 35,472), 7 (n = 31,266), 10 (n = 31,211), and 13 (n = 28,772) years old. To estimate adjusted odds ratios (ORs) with 95% confidence intervals (CIs) of overweight/obesity by each age (2.5, 4.5, 7, 10, and 13 years), a multivariate logistic regression was used adjusting for time-invariant and time-varying covariates.Results: At the age of 2.5 years, 11.0% of boys and 12.2% of girls were skipping breakfast. In fully adjusted models, skipping breakfast at 2.5 years old was not significantly associated with overweight/obesity at 2.5 and 4.5 years old, but was significantly associated with overweight/obesity at 7 and 10 years old, in both sexes. Skipping breakfast at 2.5 years old was significantly associated with overweight/obesity at 13 years old in boys (OR 1.38; 95% CI, 1.17–1.62), but not in girls (OR 1.21; 95% CI, 0.98–1.49).Conclusions: Skipping breakfast in early childhood increased overweight/obesity in later childhood, but there may be gender differences in the association.
著者
Hadiza Mohammed Inés Garcia-Lodeiro Hajime Kinoshita
出版者
Japan Concrete Institute
雑誌
Journal of Advanced Concrete Technology (ISSN:13473913)
巻号頁・発行日
vol.19, no.12, pp.1296-1308, 2021-12-23 (Released:2021-12-23)
参考文献数
28
被引用文献数
1

Large quantities of aqueous secondary waste are generated from the processing of contaminated water after the nu-clear accident in Japan. Cementation of these wastes is challenging because their significant radioactivity may cause the radiolysis of water contents in cement, posing a risk of hydrogen gas generation. The application of calcium aluminate cement modified with phosphates (CAP), as an alternative cementing system, is interesting because this system is based on acid-base reaction, and its water content can be reduced by mild heating once the system is mixed. The present study focused in the use of Secar 71, a calcium aluminate cement with a high alumina and low silica compositions, and its effects of on the production of CAP system at elevated temperatures. The modification of Secar 71 with phosphates was successful, and the reduction of water content by about 35% was achieved in the CAP system containing SrCl2 after curing the system at 80°C for 7 days. The micro cracks, typically observed in the CAP system cured at lower temperature, was significantly reduced by curing at 80°C. The obtained results show a potential of Secar 71 to prepare CAP for cementation of aqueous secondary wastes.
著者
Jae-Suk Choi Min-Hee Jeon Woi-Sook Moon Jin-Nam Moon Eun Jin Cheon Joo-Wan Kim Sung Kyu Jung Yi-Hwa Ji Sang Wook Son Mi-Ryung Kim
出版者
The Pharmaceutical Society of Japan
雑誌
Biological and Pharmaceutical Bulletin (ISSN:09186158)
巻号頁・発行日
vol.37, no.1, pp.44-53, 2014-01-01 (Released:2014-01-01)
参考文献数
45
被引用文献数
19 32

The potential hair growth-promoting activity of rice bran supercritical CO2 extract (RB-SCE) and major components of RB-SCE, linoleic acid, policosanol, γ-oryzanol, and γ-tocotrienol, were evaluated with the histological morphology and mRNA expression levels of cell growth factors using real-time reverse transcriptase-polymerase chain reaction (PCR) in C57BL/6 mice. RB-SCE showed hair growth-promoting potential to a similar extent as 3% minoxidil, showing that the hair follicles were induced to be in the anagen stage. The numbers of the hair follicles were significantly increased. In addition, mRNA expression levels of vascular endothelial growth factor (VEGF), insulin-like growth factor-1 (IGF-1), and keratinocyte growth factor (KGF) were also significantly increased and that of transforming growth factor-β (TGF-β) decreased in RB-SCE-treated groups. Among the major components of RB-SCE, linoleic acid and γ-oryzanol induced the formation of hair follicles according to examination of histological morphology and mRNA expression levels of cell growth factors. In conclusion, our results demonstrate that RB-SCE, particularly linoleic acid and γ-oryzanol, promotes hair growth and suggests RB-SCE can be applied as hair loss treatment.
著者
Ki-Hun Kim Gi-Byoung Nam Eun-Sun Jin Dong-Kie Kim Sang-Hoon Seol Doo-Il Kim HyungOh Choi Yoo Ri Kim Sung-Hwan Kim Kee-Joon Choi You-Ho Kim
出版者
The Japanese Circulation Society
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
vol.77, no.3, pp.619-625, 2013 (Released:2013-02-25)
参考文献数
22
被引用文献数
5 5

Background: Prompt diagnosis and management of atrial tachyarrhythmias (ATAs) during catheter ablation of atrial fibrillation (AF) is still challenging. Methods and Results: In 88 patients undergoing catheter ablation of AF, 128 regular ATAs were induced or converted from AF. The coronary sinus activation time (CSAT) around the mitral annulus (MA) was measured as the difference in activation time between the most proximal and distal poles of the coronary sinus (CS) electrodes. Entrainment pacing was performed around the MA, roof area, or cavotricuspid isthmus (CTI) depending on the CSAT result. Mechanisms of tachycardias included macro-reentry around the MA (perimitral atrial flutter [PM-AFL], n=63), roof-dependent AFL (Roof-AFL, n=14), CTI-dependent AFL (CTI-AFL, n=25), and atrial tachycardia (AT, n=26). When the CSAT was ≥45ms, the MA activation sequence was sequential, either proximal to distal or distal to proximal. When the CSAT was <45ms, the MA activation sequence was mainly non-sequential with converging or diverging patterns. CSAT <45ms was highly sensitive in ruling out PM-AFL from other left ATAs. When combined with PPI data from the MA, roof area or CTI, PM-, Roof-, CTI-AFL and AT was successfully differentiated with a high predictive accuracy. Conclusions: A diagnostic algorithm combining CSAT and entrainment pacing is helpful to assess the mechanism of ATAs during catheter ablation of AF.  (Circ J 2013; 77: 619–625)
著者
史 宇華 松村 耕平 Roberto Lopez-Gulliver 野間 春生
雑誌
研究報告コンピュータビジョンとイメージメディア(CVIM) (ISSN:21888701)
巻号頁・発行日
vol.2017-CVIM-205, no.16, pp.1-6, 2017-01-12

本論文では,マイクロソフト社の Kinect の深度画像から得られるユーザーのスケルトン情報に対して,Random Forest 分類器と AdaBoost を使用してユーザの姿勢をリアルタイムで自動認識するシステムを開発した.ここでは特に食事中の姿勢を対象とし,Kinect で深度データが含まれる悪い姿勢の学習データを録画する.これらの学習データから,ユーザーの Joint の特徴量を抽出し,悪い食事姿勢のデータベースを構築して学習し,五つの悪い姿勢を動画から自動認識できるシステムを開発した.悪い姿勢を食事中の映像から学習し,50 名の被験者に対して行った食事の映像から 93% の認識機能を実現した.本システムを応用し,将来はユーザーの悪い食事姿勢を検出した後,ユーザーにフィードバックを与え,食育トレーニングすることを目指している.
著者
Ji-Sook Kong Hye Won Woo Yu-Mi Kim Mi Kyung Kim
出版者
SOCIETY FOR FREE RADICAL RESEARCH JAPAN
雑誌
Journal of Clinical Biochemistry and Nutrition (ISSN:09120009)
巻号頁・発行日
vol.70, no.1, pp.37-45, 2022 (Released:2022-01-01)
参考文献数
49
被引用文献数
2

This study examined the associations between specific non-alcoholic beverages and high-sensitivity C-reactive protein (hs-CRP) and their interactions with obesity. The study participants were 4,999 adults aged 19–64 years from the 2015–2016 Korean National Health and Nutrition Examination Survey. The odds ratios (ORs) and 95% confidence intervals (CIs) were obtained using multivariable logistic regression analyses. In women, there was an inverse linear trend between coffee and hs-CRP status (ptrend = 0.0137), and a positive linear trend for soda was also found (≥1/week vs never or almost never, OR = 1.79, 95% CI 1.23–2.61, ptrend = 0.0127). In the stratification analyses, the associa­tions were only observed in obese women. The associations were inverse for coffee and tea but linearly positive for soda in obese women (ptrend<0.05). In men, an inverted J-shaped association between commercial fruit juice/drink and hs-CRP status was found; but after stratification by obesity, the association was linear only in obese men (ptrend<0.05, OR = 2.44, 95% CI 1.44–4.16 in ≥1/week vs never or almost never). Coffee and tea in women may be beneficially associated with hs-CRP status, but soda in women and commercial fruit juice/drink in men may be adversely, particularly for obese adults.
著者
Takahiro Kumagai Hirotaka Sakurai Taisuke Shioi Hirotaka Kato Jun-ichi Itoh Keisuke Kusaka Takashi Yamaguchi Masayuki Nakagawa Daisuke Sato
出版者
The Institute of Electrical Engineers of Japan
雑誌
IEEJ Journal of Industry Applications (ISSN:21871094)
巻号頁・発行日
vol.11, no.1, pp.117-127, 2022-01-01 (Released:2022-01-01)
参考文献数
42
被引用文献数
2

This study reveals the characteristics of switched reluctance motors (SRMs) made by blanking (a) 20HX1300 of high grade low-iron-loss silicon steel (0.20mm thickness) and (b) 2605SA1 of amorphous alloy (0.025mm thickness). The blanking of the amorphous alloy is an innovative technology for the mass production of the high efficiency amorphous-alloy-motor. The impact of the processing methods on the magnetic properties are evaluated using the ring cores processed by the following methods: the wire cutting and the blanking. On the other hand, the experiment with the SRMs processed by the blanking evaluates the characteristics depending on the material. As first prototype, 70W-SRM (40mm thickness) is manufactured by blanking 1600 sheets of the amorphous alloy and adhesively laminating them. In the experiment, the motor efficiency of the amorphous-alloy-SRM is improved by 6.9p. t. compared with that of silicon-steel-SRM. In addition, the iron loss of amorphous-alloy-SRM is reduced by 78.7% compared with that of silicon-steel-SRM.
著者
Hirosumi MIYAKAWA Huai-Hsun HSU Mizuki OGAWA Yuichi MIYAGAWA Naoyuki TAKEMURA
出版者
JAPANESE SOCIETY OF VETERINARY SCIENCE
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
pp.21-0566, (Released:2021-12-30)
被引用文献数
1

This study compared canine and feline fibroblast growth factor (FGF)-23 concentration measurements between automated chemiluminescence assay (CLEIA) and enzyme-linked immunosorbent assay (ELISA). Seventy serum samples each from dogs and cats were evaluated. FGF-23 measurements by CLEIA significantly correlated with those of ELISA in both dogs and cats. The Bland–Altman test showed that FGF-23 between CLEIA and ELISA had fixed and proportional biases, respectively, in both dogs and cats. Measurements by CLEIA were lower than those of ELISA, especially in higher serum FGF-23 concentrations. This study showed that FGF-23 concentrations in dogs and cats can be evaluated by automated CLEIA. However, FGF-23 cannot be directly compared between CLEIA and ELISA.
著者
El-Mallah M.Hassan EL-SHAMI S. BASSYOUN F. 無類井 建夫
出版者
公益社団法人 日本油化学会
雑誌
油化学 (ISSN:0513398X)
巻号頁・発行日
vol.41, no.11, pp.1101-1106, 1992-11-20
参考文献数
25
被引用文献数
1

オレイン酸メチルをモデルとしてジヒドロキシル化反応を新しい視点から研究した。試料を経時的に反応系から抜き取り, メタノール/硫酸で処理して残留するエポキシ中間体とアセチル化されたヒドロキシエステル類をそれぞれヒドロキシ-メトキシ及びジヒドロキシステアラートに変換した。キャピラリー GC-MS により各成分を同定し, さらに<SUP>13</SUP>C-NMR 及び<SUP>13</SUP>C-<SUP>1</SUP>H NMR により確認した。アンバーライトIR-120を触媒としたとき, ジヒドロキシステアラートの収率は 71.2% (オレイン酸メチルの変換率は87.7%) で, それには 50 minの反応時間で充分であった。
著者
Thekla H. Oechtering Grant S. Roberts Nikolaos Panagiotopoulos Oliver Wieben Scott B. Reeder Alejandro Roldán-Alzate
出版者
Japanese Society for Magnetic Resonance in Medicine
雑誌
Magnetic Resonance in Medical Sciences (ISSN:13473182)
巻号頁・発行日
pp.rev.2021-0105, (Released:2022-01-25)
参考文献数
83
被引用文献数
11

Evaluation of the hemodynamics in the portal venous system plays an essential role in many hepatic pathologies. Changes in portal flow and vessel morphology are often indicative of disease.Routinely used imaging modalities, such as CT, ultrasound, invasive angiography, and MRI, often focus on either hemodynamics or anatomical imaging. In contrast, 4D flow MRI facilitiates a more comprehensive understanding of pathophysiological mechanisms by simultaneously and noninvasively acquiring time-resolved flow and anatomical information in a 3D imaging volume.Though promising, 4D flow MRI in the portal venous system is especially challenging due to small vessel calibers, slow flow velocities, and breathing motion. In this review article, we will discuss how to account for these challenges when planning and conducting 4D flow MRI acquisitions in the upper abdomen. We will address patient preparation, sequence acquisition, postprocessing, quality control, and analysis of 4D flow data.In the second part of this article, we will review potential clinical applications of 4D flow MRI in the portal venous system. The most promising area for clinical utilization is the diagnosis and grading of liver cirrhosis and its complications. Relevant parameters acquired by 4D flow MRI include the detection of reduced or reversed flow in the portal venous system, characterization of portosystemic collaterals, and impaired response to a meal challenge. In patients with cirrhosis, 4D flow MRI has the potential to address the major unmet need of noninvasive detection of gastroesophageal varices at high risk for bleeding. This could replace many unnecessary, purely diagnostic, and invasive esophagogastroduodenoscopy procedures, thereby improving patient compliance with follow-up. Moreover, 4D flow MRI offers unique insights and added value for surgical planning and follow-up of multiple hepatic interventions, including transjugular intrahepatic portosystemic shunts, liver transplantation, and hepatic disease in children. Lastly, we will discuss the path to clinical implementation and remaining challenges.
著者
Shinnosuke Mori Shuichi Shimma Hiromi Masuko-Suzuki Masao Watanabe Tetsu Nakanishi Junko Tsukioka Katsumi Goto Hiroshi Fukui Nobuhiro Hirai
出版者
Japanese Society for Plant Biotechnology
雑誌
Plant Biotechnology (ISSN:13424580)
巻号頁・発行日
vol.38, no.3, pp.355-366, 2021-09-25 (Released:2021-09-25)
参考文献数
65
被引用文献数
3

We observed trees of the Japanese apricot, Prunus mume ‘Nanko’ (Rosaceae), bearing two types of flowers: 34% had blue fluorescent pollen under UV irradiation, and 66% had non-fluorescent pollen. The fluorescent pollen grains were abnormally crushed, sterile, and devoid of intine and pollenkitt. The development of microspores within anthers was investigated: in the abnormally developed anthers, tapetal cells were vacuolated at the unicellular microspore stage, and fluorescent pollen was produced. Compounds responsible for the blue fluorescence of pollen were identified as chlorogenic acid and 1-O-feruloyl-β-D-glucose. The anthers with fluorescent pollen contained 6.7-fold higher and 3.8-fold lower amounts of chlorogenic acid and N1,N5,N10-tri-p-coumaroylspermidine, respectively, compared to those with non-fluorescent pollen. The tapetal vacuolization, highly accumulated chlorogenic acid, and deficiency of N1,N5,N10-tri-p-coumaroylspermidine imply that low-temperature stress during the early unicellular microspore stage caused a failure in microsporogenesis. Furthermore, potential effects of the visual difference on the bee behavior were also discussed through the colorimetry. The sterility, likely induced by low-temperature stress, and the preference of honeybees for fluorescence may reduce the pollination efficiency of P. mume.
著者
Ya-Fen Ye Chao Ying Yue-Xiang Jiang Chun-Na Li
出版者
Fuji Technology Press Ltd.
雑誌
Journal of Advanced Computational Intelligence and Intelligent Informatics (ISSN:13430130)
巻号頁・発行日
vol.21, no.6, pp.1017-1025, 2017-10-20 (Released:2018-11-20)
参考文献数
23
被引用文献数
3

In this study, we focus on the feature selection problem in regression, and propose a new version of L1 support vector regression (L1-SVR), known as L1-norm least squares support vector regression (L1-LSSVR). The alternating direction method of multipliers (ADMM), a method from the augmented Lagrangian family, is used to solve L1-LSSVR. The sparse solution of L1-LSSVR can realize feature selection effectively. Furthermore, L1-LSSVR is decomposed into a sequence of simpler problems by the ADMM algorithm, resulting in faster training speed. The experimental results demonstrate that L1-LSSVR is not only as effective as L1-SVR, LSSVR, and SVR in both feature selection and regression, but also much faster than L1-SVR and SVR.