著者
Haruka KATAOKA Nanami KOITA Natsuko Ito KONDO Hiroshi C. ITO Momoko NAKAJIMA Kunikazu MOMOSE Hiroko IIMA Tomoo YOSHINO Tomoko AMANO Takio KITAZAWA Daiji ENDOH Nobuyoshi NAKAJIMA Hiroki TERAOKA
出版者
JAPANESE SOCIETY OF VETERINARY SCIENCE
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
pp.21-0516, (Released:2022-01-18)
被引用文献数
4

The red-crowned crane Grus japonensis in Hokkaido, Japan forms a closed population as a residence that is independent of the mainland population. Based on observations of a limited number of individuals as well as cranes in captivity, red-crowned cranes are omnivores and eat fish, worms, insects and plants in their own territories except in winter, when they are fed with dent corn that is supplied in eastern Hokkaido. DNA metabarcoding based on high throughput sequencing was carried out using universal primer sets for cytochrome oxidase subunit I gene. Feces from 27 chicks collected in June and July in the period from 2016 to 2018 and intestinal contents from 33 adult and subadult cranes that were found dead almost throughout year in 2006–2013 in the field in eastern Hokkaido were used. Although compositions varied considerably in the cranes, both insects and fish were found in adults and subadults to the same extents, while insects were predominant in chicks. Both insects and fish were detected in all seasons for adults and subadults. Horse flies, scarab beetles and weevils accounted for the most of the insects regardless of the life stage. Dace, stickleback, flatfish and sculpin were the major fish species in adults, while chicks ate almost only stickleback. The results provide the first comprehensive data on carnivorous diets in wild red-crowned cranes in eastern Hokkaido as basis for conservation of red-crowned cranes, for which the life style and area continuing to change.
著者
Clevers Hans C.
出版者
The Keio Journal of Medicine
雑誌
The Keio Journal of Medicine (ISSN:00229717)
巻号頁・発行日
vol.68, no.4, pp.95, 2019
被引用文献数
37

<p>Stem cells are the foundation of all mammalian life. Stem cells build and maintain our bodies throughout life. Two types of stem cells are discerned.</p><p>1) Embryonic stem cells (ES cells) are briefly present in the early human or mouse embryo, a few days after fertilization. These ES cells can be grown indefinitely in the lab and have the potential to build each and every tissue in our body. Because of this 'pluripotency', ES cells hold great promise for therapeutic application in the field of regenerative medicine. It is also possible to take skin cells (or other cells) from adults and convert these in the lab into cells with ES properties, so called iPS cells. Many of the hurdles that ES cell technology have faced, do not exist for iPS cells.</p><p>2) Adult stem cells. Every organ in our body is believed to harbor its own dedicated stem cells. These adult stem cells replace tissue that is lost due to wear and tear, trauma and disease. Adult stem cells are highly specialized and can only produce the tissue in which they reside; they are 'multipotent'. Examples are bone marrow stem cells that make all blood cells, skin stem cells and gut stem cells. Even the brain is now known to harbor its specialized stem cells. The adult stem cells allow us to live 80-90 years, but this comes at a cost: they are the cells that most easily transform into cancer cells.</p><p>Both types of stem cells can be used to establish 'organoids', 3D structures established in a dish, that recapitulate many aspects of the organ they represent. Pluripotent stem cells can be taken through the developmental steps that establish organs during embryogenesis. This has worked particularly well for parts of the the central nervous system, the kidney and GI organs. We have shown that adult epithelial stem cells carrying the generic Lgr5 marker can be cultured under tissue-repair conditions and generate epithelial organoids directly from healthy and diseased organs such as the gut, the liver, the lung and the pancreas. Organoid technology opens a range of avenues for the study of development, physiology and disease, for drug development and for personalized medicine. In the long run, cultured mini-organs may replace transplant organs from donors and hold promise in gene therapy.</p>
著者
斉藤 哲 Brown M. Korhonen F.J. McFadden R.R. Siddoway C.S.
出版者
一般社団法人日本鉱物科学会
雑誌
日本鉱物科学会年会講演要旨集
巻号頁・発行日
vol.2010, pp.191, 2010

西南極マリーバードランドに分布するフォスディックミグマタイト-花崗岩複合岩体は、白亜紀のゴンドワナ大陸分裂に伴い隆起・削剥した東ゴンドワナ大陸古太平洋縁辺部の中~下部地殻と考えられている。当岩体には小規模な花崗岩体とミグマタイト化した片麻岩類に伴って、苦鉄質岩脈や閃緑岩の小岩体が分布している。本研究から得た苦鉄質貫入岩類のジルコンU-Pb年代は白亜紀を示した。また苦鉄質貫入岩類は中カリウム~高カリウム系列で塩基性~中間組成を持つ。微量元素パターンはLIL元素に富み、Nbの不異常を示すことからスラブ由来物の汚染を受けた岩水マントル起源と考えられる。Sr-Nd同位体データもエンリッチマントル起源を示唆する。本研究結果から、苦鉄質岩類はマントルプルーム活動に由来するのではなく、背弧拡大に関連した陸弧下マントルの融解起源と考えられる。
著者
Kazuhiro Nogita Mathew C. Greaves Benjamin D. Guymer Bernard B. Walsh James M. Kennedy Michael D. Duke Tetsuro Nishimura
出版者
The Japan Institute of Electronics Packaging
雑誌
Transactions of The Japan Institute of Electronics Packaging (ISSN:18833365)
巻号頁・発行日
vol.3, no.1, pp.104-109, 2010 (Released:2011-04-21)
参考文献数
10
被引用文献数
3 5

The authors produced a demonstration electric vehicle, "Deep Green Research," based on a Honda Civic, in which critical electrical connections were soldered with a lead-free Sn–Cu–Ni–Ge alloy. This paper reports on the team's participation and completion in the Global Green Challenge, the world's largest solar car and eco car race, from Darwin to Adelaide, Australia that was run in late October, 2009. The successful completion of this course under the harsh conditions of the Australian outback proved the high reliability of the Sn–Cu–Ni–Ge lead-free solder joints in the control panels, cables, and connectors that had to carry the heavy current required to propel the vehicle over long distances at speeds of up to 104 km/hour. The vehicle set a new record for the longest distance travelled on a single charge by a car that satisfies relevant Australian safety regulations. This distance of 360 km was achieved using lithium-ion batteries with a total capacity of 33 kWh and resulted in an award in the category "Modified Production Class — Small Car (Electric)".
著者
Andrew H. Baird Alasdair J. Edwards James R. Guest Saki Harii Masayuki Hatta Liam Lachs Hanaka Mera Frederic Sinniger David Abrego Or Ben-Zvi Omri Bronstein Patrick C. Cabaitan Vivian R. Cumbo Gal Eyal Lee Eyal-Shaham Bar Feldman Joana Figueiredo Jean-François Flot Mila Grinblat Andrew Heyward Michio Hidaka Mamiko Hirose Akira Iguchi Naoko Isomura Robert A. Kinzie Seiya Kitanobo Alyson Kuba Oren Levy Yossi Loya Takuma Mezaki Amin R. Mohamed Masaya Morita Satoshi Nojima Yoko Nozawa Rian Prasetia Eneour Puill-Stephan Catalina Ramirez-Portilla Hanna Rapuano Yaeli Rosenberg Yusuke Sakai Kazuhiko Sakai Tom Shlesinger Tullia I. Terraneo Irina Yakovleva Hiromi H. Yamamoto Kiyoshi Yamazato
出版者
The Japanese Coral Reef Society
雑誌
Galaxea, Journal of Coral Reef Studies (ISSN:18830838)
巻号頁・発行日
pp.G2021_S10O, (Released:2021-11-19)
参考文献数
27
被引用文献数
11

Sesoko Station, Okinawa, has been the site of many significant advances in coral reproductive research and it continues to be a preferred destination for both Japanese and international researchers. Consequently, there are decades of spawning observations, which we present and explore here with the aim of making it easier to predict when species spawn at Sesoko Station. The data include over 700 spawning observations from 87 species of reef-building hermatypic corals. Almost all spawning occurred between dusk and dawn, with most spawning activity concentrated in the 2 to 4 hours after sunset. Some phylogenetic patterns were evident: most Acropora species spawn on or around the 6th full moon after December 21st (the northern hemisphere winter solstice); spawning in common species of merulinids and Porites appears to be concentrated around the 7th full moon and spawning in the fungiids around the 8th and subsequent full moons. The night of peak spawning with respect to the night of the full moon varied considerably among years in common Acropora species, but was dependent on the calendar date of the full moon in May or June. Therefore, despite an extended spawning season of over three months and considerable variation in the calendar date of spawning in many species among years, the month and night of spawning are reasonably predictable for many species enhancing the value of Sesoko Station as a site for coral reproductive research.
著者
Nguyen T.B. Ho T.B. Pham C. Kawasaki S.
出版者
JAIST Press
巻号頁・発行日
2007-11

Matching documents is to find similar ones of a given document from an existing document database. It is an important problem in practice as well as in research. This paper presents a method for matching document applying to identify duplicate errors in network systems. The database we used is CISCO network errors database (CNED), a collection of documents that describe error cases occurred in network systems. Each document is a complex document composed of several parts in different types: plain text, source code, dump code, debug, etc. Our experiments are carried out for CNED but the method can be extended to many other kinds of complex documents.The original publication is available at JAIST Press http://www.jaist.ac.jp/library/jaist-press/index.htmlProceedings of KSS'2007 : The Eighth International Symposium on Knowledge and Systems Sciences : November 5-7, 2007, [Ishikawa High-Tech Conference Center, Nomi, Ishikawa, JAPAN]Organized by: Japan Advanced Institute of Science and Technology
著者
早川 達 C A
出版者
日経BP社
雑誌
日経ドラッグインフォメーションpremium
巻号頁・発行日
no.174, pp.PE17-24, 2012-04

北海道薬科大学薬物治療学分野教授。POS(Problem Oriented System)に基づく薬歴管理の第一人者。著書に『POS薬歴がすぐ書ける「薬歴スキルアップ」虎の巻』基本疾患篇、慢性疾患篇、専門疾患篇など。 今回は、みやこ薬局山科店に来局した69歳女性、石井千鶴さん(仮名)の薬歴をオーディットしました。
著者
Chun-Ho PARK Sayaka KUBONIWA Ryo MURAKAMI Nozomi SHIWA Satoshi INOUE Kazunori KIMITSUKI Ma. Ricci R. GOMEZ Mark Joseph M. ESPINO Alpha Grace B. CABIC Sheila Marie C. ESPOSO Daria L. MANALO
出版者
JAPANESE SOCIETY OF VETERINARY SCIENCE
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
vol.83, no.10, pp.1563-1569, 2021 (Released:2021-10-05)
参考文献数
27
被引用文献数
2

The rabies virus is one of the most neurotropic of all viruses infecting mammals. During the terminal phases of infection, the virus spreads to peripheral tissues, including the skin. The external skin of the nose, called the nasal planum, is a sensory organ where numerous nerve bundles and terminal nerves are distributed. Therefore, the nasal planum is expected to serve as a postmortem diagnostic material. However, the distribution of rabies virus antigens in the nasal planum in rabid animals has not yet been studied. In this study, the nasal planum was obtained from 45 rabid dogs. In all rabid dogs, the viral antigen was detected in the peripheral nerve tissues, Merkel cells, and squamous cells. The viral antigen in the epidermis exhibited three patterns: first, a diffuse positive pattern from the basal layer to the squamous layer; second, a reticular positive pattern along the cell membrane in the squamous layer; and third, a basal layer pattern of the epidermis. In the dermis, viral antigens were detected more often in lamellated corpuscles just beneath the rete pegs. These results suggest that the nasal planum could serve as a useful alternative source for postmortem diagnosis in rabies endemic countries.
著者
Y. C. Lee
出版者
FCCA(Forum: Carbohydrates Coming of Age)
雑誌
Trends in Glycoscience and Glycotechnology (ISSN:09157352)
巻号頁・発行日
vol.22, no.125, pp.95-106, 2010 (Released:2010-08-13)
参考文献数
41
被引用文献数
10 12

宿主と病原体の相互作用は、多くの場合糖鎖と糖鎖結合タンパク質(GBP)の相互作用を介する。宿主細胞上の糖鎖が病原体のGBPに結合されることもあるし、病原体上の糖鎖が宿主細胞上のGBPに結合される可能性もある。病原体の中には、宿主細胞の防御機構を巧みに利用して、自分たちの生き残りを進めるものもいる。