著者
Hiroaki OHFUJI Masashi YAMAMOTO
出版者
一般社団法人日本鉱物科学会
雑誌
Journal of Mineralogical and Petrological Sciences (ISSN:13456296)
巻号頁・発行日
vol.110, no.4, pp.189-195, 2015 (Released:2015-08-29)
参考文献数
15
被引用文献数
1 15

This study demonstrates the validity of a thin osmium coating for quantitative energy–dispersive spectroscopic (EDS) analysis, particularly for light elements such as O (and potentially C and N) in natural/synthetic minerals. An osmium coating prepared by chemical vapor deposition provides an extremely thin and uniform layer whose thickness can be controlled simply by coating time. Because of the high reproducibility and reliability of the osmium coating process, users have no difficulty in evaluating the actual coating thickness, which enables strict and precise absorption corrections (for the coating layer), even for low–energy characteristic X–rays, which are susceptible to attenuation by the coating layer itself. Our results show that oxygen concentrations in silicate and oxide minerals can be quantified correctly when using the osmium coating, whereas quantification using a carbon coating afforded values that were a few wt% lower than stoichiometry, probably due to the uncertainty of the actual coating thickness (i.e., the absorption correction was incorrect). The ability to accurately quantify oxygen may stimulate new analytical applications, such as the estimation of Fe2+/Fe3+ concentrations and water content in minerals. Furthermore, the Os–coated samples prepared for EDS analysis are also suitable for electron back–scattered diffraction (EBSD) analysis without re–polishing and re–coating, which are usually routine but time–consuming tasks in the case of carbon–coated samples.
著者
山本 郁男 岩井 勝正 井本 真澄 宇佐見 則行 ヤマモト イクオ イワイ カツマサ イモト マスミ ウサミ ノリユキ Ikuo YAMAMOTO Katsumasa IWAI Masumi IMOTO Noriyuki USAMI
雑誌
九州保健福祉大学研究紀要 = Journal of Kyushu University of Health and Welfare
巻号頁・発行日
vol.6, pp.277-285, 2005-03-25

The School of Pharmaceutical Sciences, Kyushu University of Health and Welfare located in Nobeoka City, Miyazaki Prefecture wa founded in April, 2003. This place (Nobeoka) wa famous to be called Himuka(Hyuga), an ancient name, since several handred years ago. Himuka is still used in the historical and sightseeing books. However, it was no reasons why the School of Pharmaceutical Sciences did start at this place, Nobeoka. So, we searched all over the place(Himuka) for some people related to Pharmaceuticla Sciences. As results, Kitsumon AKIZUKI(1989-1981) who lived in Nobeoka during Edo period was picked out among several persons. Although he stayed in Nobeoka only for two years, he had done many great things concerned tin the education, medicine, botany, herbalism, philology and political events. Especially, Kitsumon AKIZUKI invited Hika KAKU, a famous herbalist, from Azimu, Usa (Oita prefecture) and let him investigate and herborize the local herbs near Nobeoka. This paper deals with Kitsumon AKIZUKI and his achievement in his life.
著者
山本 正 ヤマモト タダシ Yamamoto Tadashi

山本正. 「王国」と「植民地」 : 近世イギリス帝国のなかのアイルランド. 思文閣出版. 2002. 236p. (大阪経済大学日本経済史研究所研究叢書 第12冊).
著者
Shichijo Kazuko Takatsuji Toshihiro Yamamoto Masayoshi Nakashima Masahiro
出版者
広島大学平和科学研究センター
雑誌
IPSHU English Research Report Series
巻号頁・発行日
no.28, pp.70-73, 2012-03

The explosion of a plutonium Atomic bomb over Nagasaki city in Japan took place at 1102h on August 9, 1945. Radiation dose of A-bomb survivor is practically estimated from external radiation. The alpha particles can be disregarded science they travel only a short distance through air. Plutonium remaining in the soil at Nagasaki after 24yr has been determined in 1971. In the patients subjected to the Atomic bomb there was no evidence of the introduction of radioactive material. We have already studied the preserved body cells of seven A-bombed victims in 1945, and became the first one to prove that plutonium is continuing to emit radiations after more than 60 years since the A-bomb attack. In this study, the nuclide identification of alpha-emitters in environmental samples and calibration standards has been attempted by the measurement of the alpha track length using autoradiography. Alpha track length in Nagasaki soil; Ground surface soil collected in 1979 from the Nishiyama area in Nagasaki City, 210Po, 241Am and 243Am fitted the relation curve between energy and track length of alpha-particles in the photo emulsion. Moreover, the alpha track length in Nagasaki soil was consisted with that in paraffin-embedded specimen of A-bomb cases. Therefore, the nuclide of alpha-emitters in specimen of atomic victims at Nagasaki was identified with 239,240Pu by autoradiography.
著者
Toshio Naito Keito Torikai Masafumi Mizooka Fujiko Mitsumoto Kenji Kanazawa Shiro Ohno Hiroyuki Morita Akira Ukimura Nobuhiko Mishima Fumio Otsuka Yoshio Ohyama Noriko Nara Kazunari Murakami Kouichi Mashiba Kenichiro Akazawa Koji Yamamoto Mika Tanei Masashi Yamanouchi Shoichi Senda Susumu Tazuma Jun Hayashi
出版者
一般社団法人 日本内科学会
雑誌
Internal Medicine (ISSN:09182918)
巻号頁・発行日
vol.54, no.16, pp.1989-1994, 2015 (Released:2015-08-15)
参考文献数
26
被引用文献数
7 8

Objective Although inflammatory markers, such as the white blood cell (WBC) count, erythrocyte sedimentation rate (ESR) and levels of C-reactive protein (CRP) and procalcitonin, are widely used to differentiate causes of fever of unknown origin (FUO), little is known about the usefulness of this approach. We evaluated relationships between the causes of classical FUO and the levels of inflammatory markers. Methods A nationwide retrospective study including 17 hospitals affiliated with the Japanese Society of Hospital General Medicine was conducted. Patients This study included 121 patients ≥18 years old diagnosed with "classical FUO" (axillary temperature ≥38.0°C at least twice over a ≥3-week period without elucidation of the cause on three outpatient visits or during three days of hospitalization) between January and December 2011. Results The causative disease was infectious diseases in 28 patients (23.1%), non-infectious inflammatory disease (NIID) in 37 patients (30.6%), malignancy in 13 patients (10.7%), other in 15 patients (12.4%) and unknown in 28 patients (23.1%). The rate of malignancy was significantly higher for a WBC count of <4,000 /μL than for a WBC count of 4,000-8,000 /μL (p=0.015). Among the patients with a higher WBC count, the rate of FUO due to NIID tended to be higher and the number of unknown cases tended to be lower. All FUO patients with malignancy showed an ESR of >40 mm/h. A normal ESR appeared to constitute powerful evidence for excluding a diagnosis of malignancy. In contrast, the concentrations of both serum CRP and procalcitonin appeared to be unrelated to the causative disease. Conclusion The present study identified inflammatory markers that should be considered in the differential diagnosis of classical FUO, providing useful information for future diagnosis.
著者
Masahito HARA Yusuke NISHIMURA Yasuhiro NAKAJIMA Daisuke UMEBAYASHI Masaya TAKEMOTO Yuu YAMAMOTO Shoichi HAIMOTO
出版者
社団法人 日本脳神経外科学会
雑誌
Neurologia medico-chirurgica (ISSN:04708105)
巻号頁・発行日
vol.55, no.7, pp.547-556, 2015 (Released:2015-07-15)
参考文献数
32
被引用文献数
2 7

Minimally invasive transforaminal lumbar interbody fusion (TLIF) as a short fusion is widely accepted among the spine surgeons. However in the long fusion for degenerative kyphoscoliosis, corrective spinal fixation by an open method is thought to be frequently selected. Our objective is to study whether the mini-open TLIF and corrective TLIF contribute to the improvement of the spinal segmental and global alignment. We divided the patients who performed lumbar fixation surgery into three groups. Group 1 (G1) consisted of mini-open TLIF procedures without complication. Group 2 (G2) consisted of corrective TLIF without complication. Group 3 (G3) consisted of corrective TLIF with instrumentation-related complication postoperatively. In all groups, the lumbar lordosis (LL) highly correlated with developing surgical complications. LL significantly changed postoperatively in all groups, but was not corrected in the normal range in G3. There were statistically significant differences in preoperative and postoperative LL and mean difference between the pelvic incidence (PI) and LL between G3 and other groups. The most important thing not to cause the instrumentation-related failure is proper correction of the sagittal balance. In the cases with minimal sagittal imbalance with or without coronal imbalance, short fusion by mini-open TLIF or long fusion by corrective TLIF contributes to good clinical results if the lesion is short or easily correctable. However, if the patients have apparent sagittal imbalance with or without coronal imbalance, we should perform proper correction of the sagittal spinal alignment introducing various technologies.
著者
Morihiko Oya Takao Tanimoto Takayuki Yamamoto Yukiya Hakozaki
出版者
一般社団法人 日本内科学会
雑誌
Internal Medicine (ISSN:09182918)
巻号頁・発行日
vol.54, no.14, pp.1803-1808, 2015 (Released:2015-07-15)
参考文献数
30
被引用文献数
8

A 33-year-old previously healthy man injured his gums and subsequently developed dyspnea and fever. A chest X-ray showed nodules and infiltrates in both lungs, and the patient was initially diagnosed with pneumonia and administered meropenem hydrate, although his symptoms did not improve. A blood culture identified Fusobacterium necrophorum, and thrombophlebitis in the internal jugular vein of the neck was observed on computed tomography and ultrasound scans. We replaced the meropenem with clindamycin, sulbactam/ampicillin and metronidazole, and the patient's symptoms improved.
著者
Shingo ISHIKAWA Hiroshi TAKEMITSU Makoto HABARA Nobuko MORI Ichiro YAMAMOTO Toshiro ARAI
出版者
公益社団法人 日本獣医学会
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
pp.15-0245, (Released:2015-07-13)
被引用文献数
4

Nuclear factor κB (NF-κB) is a key factor in the development of chronic inflammation and is deeply involved in age-related and metabolic diseases development. These diseases have become a serious problem in cats. Sirtuin 1 (SIRT1) is associated with aging and metabolism through maintaining inflammation via NF-κB. In addition, fibroblasts are considered an important factor in the development of chronic inflammation. Therefore, we aimed to examine the effect of cat SIRT1 (cSIRT1) on NF-κB in cat fibroblast cells. The up-regulation of NF-κB transcriptional activity and pro-inflammatory cytokine mRNA expression by p65 subunit of NF-κB and lipopolysaccharide was suppressed by cSIRT1 in cat fibroblast cells. Our findings show that cSIRT1 is involved in the suppression of inflammation in cat fibroblast cells.
著者
Takahisa YAMAMOTO Koshi MITACHI Takashi SUZUKI
出版者
社団法人 日本機械学会
雑誌
JSME International Journal Series B Fluids and Thermal Engineering (ISSN:13408054)
巻号頁・発行日
vol.48, no.3, pp.610-617, 2005 (Released:2006-02-15)
参考文献数
13
被引用文献数
16 24

The Molten Salt Reactor (MSR) is a thermal neutron reactor with graphite moderation and operates on the thorium-uranium fuel cycle. The feature of the MSR is that fuel salt flows inside the reactor during the nuclear fission reaction. In the previous study, the authors developed numerical model with which to simulate the effects of fuel salt flow on the reactor characteristics. In this study, we apply the model to the steady-state analysis of a small MSR system and estimate the effects of fuel flow. The model consists of two-group neutron diffusion equations for fast and thermal neutron fluxes, transport equations for six-group delayed neutron precursors and energy conservation equations for fuel salt and the graphite moderator. The following results are obtained: (1) in the rated operation condition, the peaks of the neutron fluxes slightly move toward the bottom from the center of the reactor and the delayed neutron precursors are significantly carried by the fuel salt flow, and (2) the extension of residence time in the external-loop system and the rise of the fuel inflow temperature show weak negative reactivity effects, which decrease the neutron multiplication factor of the small MSR system.
著者
Masahiro MIYABE Azusa GIN Eri ONOZAWA Mana DAIMON Hana YAMADA Hitomi ODA Akihiro MORI Yutaka MOMOTA Daigo AZAKAMI Ichiro YAMAMOTO Mariko MOCHIZUKI Toshinori SAKO Katsutoshi TAMURA Katsumi ISHIOKA
出版者
公益社団法人 日本獣医学会
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
pp.15-0031, (Released:2015-05-10)
被引用文献数
2 11

G protein-coupled receptor (GPR) 120 is an unsaturated fatty acid receptor, which is associated with various physiological functions. It is reported that the genetic variant of GPR120, p.Arg270His, is detected more in obese people, and this genetic variation functionally relates to obesity in humans. Obesity is a common nutritional disorder also in dogs, but the genetic factors have not ever been identified in dogs. In this study, we investigated the molecular structure of canine GPR120 and searched for candidate genetic variants which may relate to obesity in dogs. Canine GPR120 was highly homologous to those of other species, and seven transmembrane domains and two N-glycosylation sites were conserved. GPR120 mRNA was expressed in lung, jejunum, ileum, colon, hypothalamus, hippocampus, spinal cord, bone marrow, dermis and white adipose tissues in dogs, as those in mice and humans. Genetic variants of GPR120 were explored in client-owned 141 dogs, resulting in that 5 synonymous and 4 non-synonymous variants were found. The variant c.595C>A (p.Pro199Thr) was found in 40 dogs, and the gene frequency was significantly higher in dogs with higher body condition scores, i.e. 0.320 in BCS4-5 dogs, 0.175 in BCS3 dogs and 0.000 in BCS2 dogs. We conclude that c.595C>A (p.Pro199Thr) is a candidate variant relating to obesity, which may be helpful for nutritional management of dogs.
著者
Susumu YAMAMOTO Hiroya HASHIZUME Jiro HITOMI Masatsugu SHIGENO Shoichi SAWAGUCHI Haruki ABE Tatsuo USHIKI
出版者
国際組織細胞学会
雑誌
Archives of Histology and Cytology (ISSN:09149465)
巻号頁・発行日
vol.63, no.2, pp.127-135, 2000 (Released:2005-11-22)
参考文献数
18
被引用文献数
29 49

The present study was designed to analyze the subfibrillar structure of corneal and scleral collagen fibrils by scanning electron microscopy (SEM) and atomic force microscopy (AFM). Isolated collagen fibrils of the bovine cornea and sclera were fixed with 1% OsO4, stained with phosphotungstic acid and uranyl acetate, dehydrated in ethanol, critical point-dried, metal-coated, and observed in an in-lens type field emission SEM. Some isolated collagen fibrils were fixed with 1% OsO4, dehydrated, critical point-dried and observed without metal-coating in an AFM. Isolated collagen fibrils treated with acetic acid were also examined by SEM and AFM. SEM and AFM images revealed that corneal and scleral collagen fibrils had periodic transverse grooves and ridges on their surface; the periodicity (i. e., D-periodicity) was about 63 nm in the cornea and about 67 nm in the sclera. Both corneal and scleral collagen fibrils contained subfibrils running helicoidally in a rightward direction to the longitudinal axis of the fibril; the inclination angle was about 15° in the corneal fibrils and 5° in the scleral fibrils. These findings indicate that the different D-periodicity between corneal and scleral fibrils depends on the different inclinations of the subfibrils in each fibril. The present study thus showed that corneal collagen fibrils differ from scleral collagen fibrils not only in diameter but also in substructure.
著者
Atsushi Mizuno Takeshi Yamamoto Yasuhiro Tanabe Toru Obayashi Morimasa Takayama Ken Nagao Tokyo CCU Network Scientific Committee
出版者
日本循環器学会
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
vol.79, no.4, pp.889-891, 2015-03-25 (Released:2015-03-25)
参考文献数
11
被引用文献数
4 8

Background:The Pulmonary Embolism Severity Index (PESI) and simplified PESI (sPESI) have not been fully evaluated in Japan, so the present study aimed to evaluate these risk stratification models in the prediction of mortality of affected patients in Japan.Methods and Results:We retrospectively analysed 302 PE patients (63.9±17.2 years of age; 42.4% male) from January 2011 to December 2012 using data from the Tokyo CCU Network. The areas under the receiver-operating characteristic curves were 0.92 (95% confidence interval (CI): 0.88–0.97) for the PESI and 0.88 (95% CI: 0.77–0.98) for the sPESI.Conclusions:Both scores can be used to predict PE mortality in Japan. (Circ J 2015; 79: 889–891)
著者
Tomoe Shimada Tomimasa Sunagawa Kiyosu Taniguchi Yuichiro Yahata Hajime Kamiya Kumi Ueno Yamamoto Yoshinori Yasui Nobuhiko Okabe
出版者
国立感染症研究所 Japanese Journal of Infectious Diseases 編集委員会
雑誌
Japanese Journal of Infectious Diseases (ISSN:13446304)
巻号頁・発行日
vol.68, no.2, pp.151-158, 2015 (Released:2015-03-23)
参考文献数
46
被引用文献数
1 7

This study reports the epidemiological characteristics of hospitalized cases of influenza A(H1N1)pdm09 infection analyzed on the basis of surveillance data collected from July 24, 2009, the date on which the hospital-based surveillance of influenza cases was implemented in Japan, to September 5, 2010. During the study period, 13,581 confirmed cases were reported. Among those cases with information regarding the reason for hospitalization, 39% were admitted to hospitals for non-therapeutic purposes such as medical observation and laboratory testing. The overall hospitalization rate was 5.8 cases per 100,000 population when cases hospitalized for non-therapeutic purposes were excluded. While those aged under 20 years accounted for over 85% of hospitalized cases, the largest proportion of fatal cases was observed in those aged over 65 years. The overall case fatality rate for all hospitalized cases was 1.5%. The year-round surveillance for hospitalized influenza-like illness cases was launched in 2011, and it was expected that this surveillance system could add value by monitoring changes in the epidemiological characteristics of hospitalized cases of seasonal influenza.
著者
Iketani Hiroyuki Ohta Satoshi Kawahara Takayuki Katsuki Toshio Mase Nobuko Sato Yoshihiko Yamamoto Toshiya
出版者
日本育種学会
雑誌
Breeding science (ISSN:13447610)
巻号頁・発行日
vol.57, no.1, pp.1-6, 2007-03
被引用文献数
2

'Somei-yoshino' (Yoshino cherry, Prunus × yedoensis) is the most popular flowering cherry cultivar in Japan. In order to confirm the clonal status of this cultivar, which is one of the most important issues, genotypes of different individuals were investigated using 21 microsatellite markers. Of the 52 individuals examined, including 47 old trees planted from the late 19th to the early 20th century that had been collected from various locations in Japan, 50 showed an identical genotype. The other two were assumed to be the offspring of this cultivar. These results showed that 'Somei-yoshino' is a clone from a single tree. The genealogy of six other cultivars belonging to the same hybrid species was examined using the same method. The results were congruent with the documentation of their genealogy. 'Mishima-zakura' and 'Shouwa-zakura' were found to be the offspring of 'Somei-yoshino', while 'Amagi-yoshino', 'Izu-yoshino', 'Mikado-yoshino' and 'Perpendens' were not directly related to 'Somei-yoshino'.