著者

山本 健太郎 Kentaro Yamamoto

雑誌

法と政治 (ISSN:02880709)

巻号頁・発行日

vol.58, no.3/4, pp.31(1012)-102(941), 2008-01-20

著者

山本 健太郎 Kentaro Yamamoto

雑誌

博士学位論文 : 内容の要旨と審査結果の要旨

巻号頁・発行日

no.51集, pp.77-81, 2012-05-31

著者

山本 健太郎 Kentaro Yamamoto

巻号頁・発行日

2011

著者

Yajima Takeshi Koshiko Masaki Zhang Yaoqing Oguchi Tamio Yu Wen Kato Daichi Kobayashi Yoji Orikasa Yuki Yamamoto Takafumi Uchimoto Yoshiharu Green Mark A Kageyama Hiroshi

出版者

Springer Nature

雑誌

Nature communications (ISSN:20411723)

巻号頁・発行日

vol.7, 2016-12-14

被引用文献数

10

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重金属を固体中で選択的に吸収する材料の発見 : 電子機器からの新たな金属回収法などの開発に期待. 京都大学プレスリリース. 2016-12-20.

著者

Shinya MIZUTANI Shidow TORISU Yasuyuki KANEKO Shushi YAMAMOTO Shinsuke FUJIMOTO Benedict Ong Huai ERN Kiyokazu NAGANOBU

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.16-0562, (Released:2016-12-17)

被引用文献数

20

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The pathophysiology of canine gallbladder diseases, including biliary sludge, gallbladder mucoceles, and gallstones, is poorly understood. This study aimed to evaluate the composition of gallbladder contents and bacterial infection of the gallbladder in order to elucidate the pathophysiology of biliary sludge and gallbladder mucoceles. A total of 43 samples of canine gallbladder contents (biliary sludge, 21 and gallbladder mucoceles, 22) were subjected to component analysis by infrared spectroscopy, and the resultant infrared spectra were compared with that of swine mucin. Of the 43 samples, 41 were also evaluated by aerobic and anaerobic bacterial culture. The contents of 20 (95.2%) biliary sludge and 22 (100%) gallbladder mucocele samples exhibited similar infrared spectra as swine mucin. Although biliary sludge and gallbladder mucocele contents exhibited similar infrared spectra, one sample of biliary sludge (4.8%) was determined to be composed of proteins. The rate of bacterial infection of the gallbladder was 10.0% for biliary sludge and 14.3% for gallbladder mucoceles. Almost all of the identified bacterial species were intestinal flora. These results indicate that the principal components of gallbladder contents in both gallbladder mucoceles and biliary sludge are mucins and that both pathophysiologies exhibit low rates of bacterial infection of the gallbladder. Therefore, it is possible that gallbladder mucoceles and biliary sludge have the same pathophysiology, and, rather than being independent diseases, they could possibly represent a continuous disease. Thus, biliary sludge could be considered as the stage preceding the appearance of gallbladder mucoceles.

著者

Shuji Fujii Yuki Yamamoto

出版者

特定非営利活動法人日本バイオレオロジー学会

雑誌

Journal of Biorheology (ISSN:18670466)

巻号頁・発行日

vol.30, no.1, pp.27-33, 2016 (Released:2016-10-25)

参考文献数

36

被引用文献数

2

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Kinetics of the orientation transition in the triblock copolymer lamellar phase is studied by viscometry. We find that the strain-controlled mechanism dominates the transition kinetics. We propose a possible scenario of the orientation transition from the viewpoint of the dislocation dynamics. We could also evaluate the critical shear rate of the orientation transition by assuming the limiting velocity of the dislocations under shear. Evaluated value is in good agreement with the experimental observation. The nucleation of the dislocations might be necessary for the orientation transition.

著者

Gerhard N. SCHRAUZER Tammy MOLENAAR Sherri MEAD Klaus KUEHN Hiroshi YAMAMOTO Eiji ARAKI

出版者

The Japanese Cancer Association

雑誌

Japanese Journal of Cancer Research GANN (ISSN:09105050)

巻号頁・発行日

vol.76, no.5, pp.374-377, 1985 (Released:2008-03-17)

参考文献数

15

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Selenium concentrations in whole blood of Japanese and American women with and without breast cancer and benign fibrocystic breast disease were determined. The observed blood Se levels of healthy Japanese women (0.286±0.021μg/ml) were similar to previously reported values for healthy Japanese adults. The Japanese patients with benign breast disease and with breast cancer exhibited blood selenium concentrations of 0.200±0.045 and 0.195±0.057μg/ml, respectively. The mean blood Se concentration of Japanese breast cancer patients with recurrence was 0.188±0.061μg/ml. The mean blood Se concentrations of healthy American women from San Diego, Calif., were 0.191±0.023μg/ml; of women with benign fibrocystic disease, 0.142±0.010μg/ml; and of breast cancer patients, 0.167±0.032μg/ml. The higher blood Se concentrations of Japanese healthy subjects as compared to healthy Americans can be attributed to differences in the dietary Se intakes; low blood Se concentration may be indicative of increased breast cancer risk.

著者

吉川 瑛治レオナルド Robson Ryu Yamamoto José Luiz Petri Fernando José Hawerroth 山根 健治 本條 均

出版者

一般社団法人 園芸学会

雑誌

園芸学研究 (ISSN:13472658)

巻号頁・発行日

vol.13, no.2, pp.143-153, 2014 (Released:2014-06-30)

参考文献数

25

被引用文献数

1 3

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ニホンナシ‘幸水’と‘豊水’の鉢植え樹を供試し,2007,2009,2010および2011年度の4か年にわたりシアナミド剤の散布処理を行った.その後22°Cの自然光ガラス室に移動させ,発芽・開花状態を調査した.ニホンナシの自発休眠覚醒の指標とされる7.2°C以下低温遭遇時間と,発育速度(DeVelopmental Rate, DVR)モデルによる発育指数(DeVelopmental Indexes, DVI)を対比させ,シアナミド剤の散布時期の有効範囲の設定を試みた.なお,DVI1は大谷(2006),杉浦(1997),が定義している,自発休眠覚醒期中の-6~12°Cの温度範囲を対象としたものである.そのDVI1は本研究でDVI(old)と定義した.一方,杉浦ら(2003)は自発休眠覚醒期中の21~24°Cの温度域は低温積算の一部を打ち消して自発休眠を逆進させる効果があると報告している.その報告に基づき求めたDVI1をここではDVI(new)と定義した.その結果,7.2°C以下の低温遭遇400~600時間処理の時点でシアナミド処理をすると,両品種の自発休眠打破の促進効果が認められた.両品種ともにDVI(new)(杉浦ら,2003)が0.65~0.70の範囲内でシアナミド処理すると,発芽および開花が改善され,開花日も促進した.DVI(old)(杉浦,1997)とDVI(new)において,発育ステージが進行し,DVI(old)では,1.03以上,DVI(new)では,0.80以上では処理の効果は弱まる傾向を示した.2011年度の秋冬季(10~2月)では他の年次より21°C以上に遭遇した時間が68時間長かったため,低温遭遇時間のみでシアナミド剤の散布時期を特定することは困難であったが,高温時の打ち消しを考慮したDVI(new)は,発育ステージを適正に評価した.以上の結果から,低温代替技術として,シアナミド処理を行う場合,気候温暖化に対応可能なDVI(new)モデルによる散布時期の予測が有効であることが示唆された.

著者

Atsushi Shimada Tatsuya Kubo Shigeto Tominaga Masashi Yamamoto

出版者

一般社団法人 園芸学会

雑誌

The Horticulture Journal (ISSN:21890102)

巻号頁・発行日

vol.86, no.2, pp.194-199, 2017 (Released:2017-04-25)

参考文献数

27

被引用文献数

8

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The effects of temperature and light on photosynthetic, chlorophyll fluorescence characteristics under high temperature in the passion fruits ‘Summer Queen’ (P. edulis × P. edulis f. flavicarpa) and ‘Ruby Star’ (P. edulis × P. edulis f. flavicarpa) were examined. Photosynthetic rates of both cultivars markedly and linearly increased up to 300 μmol·m−2·s−1, and less markedly increased from 300 to 1500 μmol·m−2·s−1 under several light conditions. Their light saturation points were recorded at around 1200 μmol·m−2·s−1 photosynthetic photon flux densities (PPFD). Regarding the relationship between temperature and photosynthesis, the maximum value of the apparent photosynthetic rate of ‘Summer Queen’ was observed at 30°C, and it was lower at both lower and higher temperatures. In ‘Ruby Star’, on the other hand, the maximum value was observed at 20 to 30°C, and this decreased at 35 and 40°C. The gross photosynthetic rate of ‘Summer Queen’ decreased over 30°C whereas in ‘Ruby Star’, it decreased to a lesser extent. The transpiration rate of ‘Ruby Star’ was higher than that of ‘Summer Queen’ at 40°C. Dark respiration increased from 20 to 40°C in both cultivars. Concerning chlorophyll fluorescence characteristics, ‘Summer Queen’ showed high-temperature injury at 40°C and all parameters were significantly decreased at 45°C. On the other hand, Fv/Fm showed only a slight decrease at 45°C in ‘Ruby Star’. These results indicate that ‘Summer Queen’ is susceptible to heat stress and that the range of its optimal temperature for photosynthesis is lower than ‘Ruby Star’.

著者

Atsushi Imai Takeshi Kuniga Terutaka Yoshioka Keisuke Nonaka Nobuhito Mitani Hiroshi Fukamachi Naofumi Hiehata Masashi Yamamoto Takeshi Hayashi

出版者

一般社団法人 園芸学会

雑誌

The Horticulture Journal (ISSN:21890102)

巻号頁・発行日

pp.OKD-013, (Released:2016-09-24)

被引用文献数

12

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We analyzed the pedigree records (1995–2010) of the Kuchinotsu Citrus Breeding Program (KCBP) at the National Institute of Fruit Tree Science (NIFTS) in Japan, abbreviated as NIFTS-KCBP, to reveal the genetic background and current status of inbreeding and genetic uniformity of the parental cultivars/genotypes and their F1 breeding progenies. The founding genotypes mostly used for crossing in NIFTS-KCBP were satsuma mandarin (Citrus unshiu Marcow.), sweet orange (C. sinensis [L.] Osbeck), king mandarin (C. nobilis Lour.), clementine (C. clementina hort. ex Tanaka), mediterranean mandarin (C. deliciosa Ten.), dancy tangerine (C. tangerina hort. ex Tanaka), and ponkan (C. reticulata Blanco). The intensive use of these seven genotypes and their progenies as crossed parents has led to a high degree of inbreeding in the breeding population. Moreover, these seven genotypes have dominated about 80% of the genetic composition of the breeding population. Although further studies are needed to reveal the influence of inbreeding and genetic uniformity on agronomically important traits, these data offer useful information for the selection of cross combinations and breeding strategies in the ongoing NIFTS citrus breeding program, Japan.

著者

山本 圭子 Keiko Yamamoto

雑誌

人文論究 (ISSN:02866773)

巻号頁・発行日

vol.41, no.2, pp.40-52, 1991-10-20

著者

Yasuyo HATANO Shigeyoshi YAMAMOTO

出版者

Society of Computer Chemistry, Japan

雑誌

Journal of Computer Chemistry, Japan -International Edition (ISSN:2189048X)

巻号頁・発行日

vol.2, pp.2016-0003, 2016 (Released:2016-09-03)

参考文献数

31

被引用文献数

1

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A Fortran program is given for calculating wave functions of the molecular hydrogen ion, expanded in terms of single-center Laguerre-type orbitals. Using this program, the radial quantum number has been extended to 203, and accuracy has been attained in energy of the order of 10−6 a.u. The electron-nucleus Coulomb integrals are evaluated numerically by applying Gaussian quadratures.

著者

Yoshiaki Yamamoto Yuki Kawamura Yuki Yamazaki Tatsuro Kijima Toshiya Morikawa Yoshimune Nonomura

出版者

公益社団法人 日本油化学会

雑誌

Journal of Oleo Science (ISSN:13458957)

巻号頁・発行日

pp.ess14176, (Released:2015-02-09)

被引用文献数

2 22

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Palmitoleic acid is a promising bactericidal agent for cleansing products with alternative bactericidal abilities. In this study, we focus on the physical and biological activity of palmitoleic acid calcium salt (C16:1 fatty acid Ca salt) because it forms via an ion-exchange reaction between palmitoleic acid and Ca ions in tap water, and remains on the skin surface during the cleansing process. Here, we prepared C16:1 fatty acid Ca salt to investigate its crystal structure and physical and bactericidal properties. The Ca salt was a plate-shaped lamellar crystalline powder with a particle diameter of several micrometers to several tens of micrometers; it exhibited significant lubricity and alternative bactericidal activity against Staphylococcus aureus (S. aureus) and Propionibacterium acnes (P. acnes). We also examined other fatty acid Ca salts prepared from lauric acid (C12:0 fatty acid), palmitic acid (C16:0 fatty acid), and oleic acid (C18:1 fatty acid). The bactericidal activities and lubricity of the fatty acid Ca salts changed with the alkyl chain length and the degree of unsaturation. The C16:1 fatty acid Ca salt exhibited the strongest selective bactericidal ability among the four investigated fatty acid Ca salts. These findings suggest that C16:1 fatty acid and its Ca salt have potential applications in cleansing and cosmetic products.

著者

Misa Yamamoto Toshihiko Yamauchi Kozue Okano Mutsuo Takahashi Shoji Watabe Yoshimi Yamamoto

出版者

東北ジャーナル刊行会

雑誌

The Tohoku Journal of Experimental Medicine (ISSN:00408727)

巻号頁・発行日

vol.217, no.3, pp.193-201, 2009 (Released:2009-03-13)

参考文献数

28

被引用文献数

11 18

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Neurofibromas are benign tumors that comprise primarily of Schwann cells and fibroblasts. Mast cells have been found scattered in the tumor tissue, and their role in promoting the proliferation of neurofibroma has been suggested. Tranilast (N-[3,4-dimethoxycinnamolyl]anthranilic acid) is an anti-allergic drug that inhibits release of the chemical mediators from mast cells and it used for the treatment of keloids and hypertrophic scars by its inhibition of growth-promoting transforming growth factor (TGF)-β1 from fibroblasts. We assumed that tranilast would suppress neurofibroma cell growth. In order to prove this hypothesis, we investigated the effectiveness of tranilast in inhibiting the tumor growth using a new cell culture system obtained from patients with neurofibromas. We called this culture system with the mixture of Schwann cells and fibroblasts “NF1 cells culture”. Mast cells were differentiated from CD34+ peripheral blood mononuclear cells of normal healthy subjects, and were co-cultured with NF1 cells. Three days after tranilast (10 ∼ 100 μM) added to the culture dishes, we counted viable cell numbers and measured the concentrations of TGF-β1, stem cell factor (SCF) and tryptase, which exists in the histamine granule, in the culture medium. Tranilast significantly suppressed proliferation of the NF1 cells and lowered the levels of TGF-β1, SCF and tryptase. These results suggest that tranilast retards tumor proliferation through not only suppression of cell growth factor, but also the inhibition of a chemical mediator released from mast cells. Thus, tranilast can be a potent therapeutic agent to inhibit the growth of neurofibromas.

著者

Shigeki Moriya Miyuki Kunihisa Kazuma Okada Hiroshi Iwanami Hiroyoshi Iwata Mai Minamikawa Yuichi Katayose Toshimi Matsumoto Satomi Mori Harumi Sasaki Takashi Matsumoto Chikako Nishitani Shingo Terakami Toshiya Yamamoto Kazuyuki Abe

出版者

一般社団法人 園芸学会

雑誌

The Horticulture Journal (ISSN:21890102)

巻号頁・発行日

pp.MI-156, (Released:2016-07-23)

被引用文献数

21

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During apple (Malus × domestica Borkh.) storage, a loss in fruit firmness can occur. This is frequently associated with mealiness, an undesirable trait. There have been studies, such as phenotypic analyses and transcriptomics, as well as others employing a transgenic approach, focusing on this trait. Certain genetic approaches, such as quantitative trait loci (QTL) approach, however, have not been attempted. In this study, to identify and characterize QTLs controlling flesh mealiness and to investigate their application in apple breeding, we performed classical QTL mapping based on a bi-parental population and a genome-wide association study (GWAS) of mealiness. Phenotypic data for mealiness allowed us to identify two QTLs in the bi-parental family located on linkage group 10. The GWAS discovered significant marker-trait associations on chromosomes 2, 9, and 10. The MdPG1 locus, located on chromosome 10, was identified as the locus with the strongest significance by both QTL mapping and GWAS, suggesting its primary contribution to flesh mealiness. Using a tri-allelic simple sequence repeat marker, Md-PG1SSR10kd, 10 kb downstream of the MdPG1 coding sequence, we divided apple accessions into six groups based on their genotypes. Among the six groups, the Md-PG1SSR10kd genotype “2/2” had the least mealy phenotype.

著者

Miriam Valle Arizaga Oscar Fabián Villalobos Navarro Carlos Roman Castillo Martinez Esmeralda Judith Cruz Gutiérrez Humberto Antonio López Delgado Shin‑ichi Yamamoto Kazuo Watanabe Takao Niino

出版者

一般社団法人 園芸学会

雑誌

The Horticulture Journal (ISSN:21890102)

巻号頁・発行日

pp.OKD-002, (Released:2016-07-16)

被引用文献数

19

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We modified the D cryo-plate protocol by paper mounting to the cryo-plate with alginate gel and shoot tips, and cryopreserved shoot tips of 13 potato genotypes (potato genetic resources in Mexico) using the revised and optimized D cryo-plate protocol. There were no significant differences in regrowth of cryopreserved shoot tips by addition of the paper mounting step to the base D cryo-plate protocol, besides a reduction in dropping shoot tips in steps during the whole procedure. Some steps of revised D cryo-plate protocol were optimized or reconfirmed, and the effect of optimizations such as cold-hardening, loading solution treatment, and post-rewarming treatment on the regeneration of shoot tips was studied. This optimized protocol was successfully applied to ‘B-71-240-2’ and 12 additional potato genotypes, resulting in 70.0%–93.3% regrowth with an average of 82.8% and stable storage for 1 year. When introducing new cryopreservation techniques, modification and optimization of the method are required to adjust to each laboratory’s circumstances. This optimized D cryo-plate method will facilitate cryobanking of potato and other plant genetic resources in Mexico for long-term preservation in a genebank.

著者

Tsuneyuki Yamamoto Kusnandar Anggadiredja Takato Hiranita

出版者

(公社)日本薬理学会

雑誌

Journal of Pharmacological Sciences (ISSN:13478613)

巻号頁・発行日

vol.96, no.4, pp.382-388, 2004 (Released:2004-12-22)

参考文献数

51

被引用文献数

16 23

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Growing evidence on the involvement of cannabinoids in the rewarding effects of various kinds of drugs of abuse has suggested that not only the classical dopaminergic and opioidergic, but also the most recently established endocannabinoid system is implicated in the brain reward system. Furthermore, the interplay between the three systems has been shown to be an essential neural substrate underlying many aspects of drug addiction including craving and relapse. Relapse, the resumption of drug taking following a period of drug abstinence, is considered the main hurdle in treating drug addiction. Yet, little is known about its underlying mechanisms. The link between the endocannabinoid system and the arachidonic cascade is currently being clarified. While several findings have, indeed, shown the essential role of the endocannabinoid system in the reinstatement model, the endocannabinoid-arachidonic acid pathway may also be an important part in the neural machinery underlying relapse. This evidence may provide an alternative approach that will open a novel strategy in combating drug addiction.

著者

KATO Hajime YAMAMOTO Masaaki YAMAGUCHI-OZAKI Tomona KADOUCHI Hiroyuki IWAMOTO Yutaka NAKAYASHIKI Hitoshi TOSA Yukio MAYAMA Shigeyuki MORI Naoki

出版者

日本植物病理学会

雑誌

Journal of general plant pathology : JGPP (ISSN:13452630)

巻号頁・発行日

vol.66, no.1, pp.30-47, 2000-02-25

被引用文献数

14

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Eighty-five Pyricularia isolates were collected from 29 host species of Gramineae, Bambusideae and Zingiberaceae plants sampled in Brazil, Uganda, Ivory Coast, India, Nepal, China, Indonesia and Japan.These isolates were compared on the basis of pathogenicity, mating ability and restriction fragment length polymorphisms with single-copy DNA probes.Based on the pathogenicity to eight differential gramineous plants, these isolates were classified into seven pathotypes:finger millet type, foxtail millet type, common millet type, rice type, crabgrass type, Italian ryegrass / weeping lovegrass type, and non-cereal / grass type.Genetic variation among these isolates was assessed by RFLP analysis with two restriction enzymes and nine single-copy DNA probes isolated from a finger millet strain.An UPGMA dendrogram based on the RFLPs revealed that the 85 isolates could be classified into seven major groups.Isolates from cereal crops(finger millet, foxtail millet, common millet, wheat and rice)and a grass, Brachiaria plantaginea, were clustered into a single group.They were further divided into six subgroups corresponding to the pathotypes.Among cereal crop isolates only an isolate from pearl millet was located into a different group.The remaining isolates were clustered into five groups designated as the crabgrass group, the buffelgrass and jungle rice group, the rice cutgrass, knotroot bristlegrass and Setaria tomentosa group, the bamboo and bamboo grass group and the Zingiber mioga group.The isolates from cereal crops were generally capable of mating with finger millet strains and constituted a closed mating compatibility group.These results suggested that the isolates from cereal crops from a single group with a common ancestor although they are pathogenic to taxonomically diverse plants.A combined analysis of the pathogenicity and genetic similarity suggested that the transmission of M.grisea isolates occurs in natural agroecosystems between finger millet and Eleusine africana, goosegrass or Bambusa arundinacea, between foxtail millet and green bristlegrass, and between rice and tail fescue, Italian ryegrass, sweet vernalgrass, reed canarygrass or Oryza longistaminata.

著者

Sato Katsutoshi Tomonaga Hiroyuki Yamamoto Tomokazu Matsumura Syo Zulkifli Nor Diana Binti Ishimoto Takayoshi Koyama Michihisa Kusada Kohei Kobayashi Hirokazu Kitagawa Hiroshi Nagaoka Katsutoshi

出版者

Nature Publishing Group

雑誌

Scientific reports (ISSN:20452322)

巻号頁・発行日

vol.6, 2016-06-24

被引用文献数

47

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ロジウムを凌駕する排ガス浄化触媒活性を有する新規合金ナノ粒子-元素間融合により電子状態を改変、優れたNOx還元活性の発現-. 京都大学プレスリリース. 2016-06-27.

著者

Masahide MATSUDA Tetsuya YAMAMOTO Eiichi ISHIKAWA Kei NAKAI Hiroyoshi AKUTSU Kuniyuki ONUMA Akira MATSUMURA

出版者

社団法人 日本脳神経外科学会

雑誌

Neurologia medico-chirurgica (ISSN:04708105)

巻号頁・発行日

vol.55, no.9, pp.749-755, 2015 (Released:2015-09-15)

参考文献数

21

被引用文献数

2 5

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Temozolomide (TMZ) as a concomitant and adjuvant chemotherapy to radiotherapy following maximal surgical resection is the established standard therapy for patients with newly diagnosed high-grade glioma. However, detailed analysis of chemotherapy-induced nausea and vomiting (CINV) associated with concomitant TMZ has not been sufficiently described. We prospectively analyzed the profile of CINV associated with concomitant TMZ. Eighteen consecutive patients with newly diagnosed high-grade glioma treated with concomitant chemoradiotherapy including TMZ were enrolled. CINV was recorded using a daily diary including nausea assessment, emetic episodes, degree of appetite suppression, and antiemetic medication use. The observed incidence rates of all grade nausea, moderate/severe (CTC grade 2, 3) nausea, emetic episodes, and appetite suppression for the overall period were 89%, 39%, 39%, and 83%, respectively. Moderate/severe nausea and severe (CTC grade 3) appetite suppression were frequently observed during the delayed phase of the treatment. Emetic episodes and moderate/severe nausea were significantly correlated with female gender. Moderate/severe nausea and severe appetite suppression were significantly correlated with low lymphocyte counts before chemoradiotherapy. For CINV associated with concomitant TMZ, enhanced antiemetic therapy focused on the delayed phase of the treatment will likely be beneficial, especially in female patients with a low lymphocyte count before chemoradiotherapy.