著者

Hiroshi Arima Yutaka Oiso

出版者

一般社団法人 日本内科学会

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

vol.49, no.19, pp.2043-2047, 2010 (Released:2010-10-01)

参考文献数

17

被引用文献数

4 20 8

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Background and objective We previously reported that baclofen, a GABAB agonist, reduces body weight in obese mice. In this clinical study, we examined the possibility that baclofen might serve as an effective therapeutic agent for obesity in humans. Methods Seven women and three men ranging from 25-51 years of age and 31.3-41.0 kg/m2 body mass index were included in the study. Baclofen, which was started at a dose of 15 mg/day and increased to 30 mg/day in 10 days, was administered for 12 weeks. Results Administration of baclofen for 12 weeks significantly decreased both body weight (baseline: 93.30 ± 9.80 kg, 12 weeks: 91.70 ± 10.30 kg) and waist circumference (baseline: 107.9 ± 9.0 cm, 12 weeks: 105.6 ± 10.0 cm). Serum leptin levels, which possibly reflect the amount of adipose stores, were also decreased significantly by the treatment. On the other hand, there were no significant changes in the blood pressure or metabolism of glucose and lipid. No adverse effects were observed. Conclusion Although the anti-obesity effects of baclofen in the present study were mild, this pilot study suggests the possibility that baclofen might serve as a new anti-obesity drug in humans.

著者

浮ヶ谷 幸代

出版者

相模女子大学

雑誌

相模女子大学紀要. A, 人文系 (ISSN:18835341)

巻号頁・発行日

vol.74, pp.7-19, 2010

著者

坂井 真一郎 佐渡 秀夫 堀 洋一

出版者

The Institute of Electrical Engineers of Japan

雑誌

電気学会論文誌. D, 産業応用部門誌 = The transactions of the Institute of Electrical Engineers of Japan. D, A publication of Industry Applications Society (ISSN:09136339)

巻号頁・発行日

vol.120, no.7, pp.761-768, 2000-06-01

被引用文献数

11 7

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Novel algorithm of the dynamic driving/braking force distribution is proposed for electric vehicle (EV) with four in-wheel motors. In such EV, the vehicle lateral motion can be controlled by yaw moment, generated with torque difference between wheels. This method is known as DYC (Direct Yaw moment Control) in normal engine vehicle engineering, however, the torque difference can be generated more directly with in-wheel motors. One problem of DYC is its instability on the slippery road, such as wet or snowy asphalt. To achieve high stability, the loads of wheels are preferable to be equal. The load of each wheel can be evaluated with root sum square of driving/braking force and side force. Therefore, the driving/braking forces, or motor torques, should be distributed depending on the side forces of wheels, to minimize the load imbalance between the wheels. The proposed algorithm can solve this optimization problem approximately with a few calculation cost, thus this method can be applied for real-time calculation within a control period. The approximate solutions with proposed method are evaluated by comparison with numerical solutions that require long calculation time. Difference between these solutions is negligible one, and this indicates the effectiveness of proposed method.

著者

芳村正秉 著

出版者

神習教大教庁

巻号頁・発行日

1902

著者

石黒 正数

巻号頁・発行日

vol.30, no.1, 2015-01-01

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表紙新シリーズの初回のテーマは「Deep Learning」です.Deep Learning で象徴的な「猫」を題材として,猫のイメージが足の部分から徐々に具現化されていく過程をモチーフとしてみました.手前のロボットは,今年の表紙の主役である,蟻をモデルとするロボットで,このロボットに搭載されている人工知能にてDeep Learningが実行されているという構図です.蟻ロボットは今後も登場する予定です! (イラスト:石黒正数)

著者

Robert D. Retherford ...

出版者

East-West Center, Population and Health Studies

巻号頁・発行日

2004

著者

村越 望

出版者

国立極地研究所

雑誌

南極資料 (ISSN:00857289)

巻号頁・発行日

vol.36, pp.42-58, 1969-12

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Forty members of the 10th Japanese Antarctic Research Expedition left Tokyo on November 30, 1968, aboard the icebreaker FUJI, under the command of Captain Shigeo MATSUSHIMA The expedition was led by Dr Kou KUSUNOKI, also leading the wintering party of 28 men and one pressman, while the author, as deputy leader, led the summer party of 12 men and one press reporter At Fremantle, West Australia, an american scientist (aeronomy) Mr Gerard A ROACH got on board the FUJI as an observer The FUJI carried 560 tons of expedition's cargo, including a single-engine monoplane Lockheed LASA-60, and was equipped with two Sikorsky S61-A helicopters and one Bell 47G2A helicopter After anchoring at Fremantle from December 15 through 21, 1968, the FUJI proceeded to Lutzow-Holm Bay and reached the edge of fast ice on January 5, 1969, without much difficulty The anchorage was about 30 nautical miles northeast of Syowa Station, and from there the first helicopter flight was made to transport men and cargo. On the following day, January 6, the FUJI reached fast ice within 1400 meters east of Syowa Station Unloading of about 560 tons of cargo and transportation to the station were carried out mainly by two S61-A helicopters, but about 65 tons of diesel oil was transmitted by a pipeline directly from the ship to the tanks on the shore, one 50kl metal tank and three 10kl rubber pillow tanks This was the first attempt of oil transportation by a pipeline. The remaining 105 tons of heavy materials were transported by snow vehicles and sledges over sea ice. Construction works was carried out until February 20, and a new living hut (20 × 5m), an extention of garage (10 × 8m), a tidal observation hut (3 × 3m), a corridor and three rocket huts, an assembly shop (11.8 × 7.6m), a telemetry and rador station (14.9 × 6.5m), and a control center (6.0 × 3.6m) were completed For the constructions, we were provided with a new 11-ton bulldozer, a 2-ton dump truck, and a concreat mixer. The scientific activities were largely the continuation from the previous years It is, however, worthy to note that a small aircraft LASA-60 was used in aerophotogrammetry during the summer period. The aerophoto survey covered the southern part of Lutzow-Holm Bay and the Yamato Mountains about 300km south of Syowa Station. In conjunction with the study of conjugate points, the high altitude balloons were released to observe auroral X-rays during summer. On January 28 and 29, four astronomical points were newly established in the southern part of Lutzow-Holm Bay Between February 3 and 10, 15 research members studied biology, geochemistry, geology, cartography and geography in the Skallen area where they reached by helicopter. On February 15, the 9th JARE pole traverse party, after the long journey of 141 days, returned to F16 camp, 15km east of Syowa Station. At F16 the helicopter picked up 11 members, records and ice samples carried them to the ship. On February 20, the station was officially handed over to the 10th wintering party, and the FUJI took a course to the north and then to the west. On February 22, a helicopter was sent out to take the research party to the rocks of the east coast of the Riiser-Larsen Peninsula, and to bring them back. On March 3, the ship turned to the north, and left Antarctica. After staying at Cape Town from March 14 to 20 and at Colombo from April 5 to 9, the ship returned to Tokyo on April 25. The shipboard observations of upper atmosphere physics, meteorology, oceanography, and biology were successfully carried out throughout the voyage.

著者

江口 譲 杉本 聡一郎 服部 康男 平口 博丸

出版者

一般社団法人 日本機械学会

雑誌

日本機械学会論文集 (ISSN:21879761)

巻号頁・発行日

pp.14-00478, (Released:2015-02-04)

参考文献数

15

被引用文献数

1

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Explanation is given about a rational method to evaluate tornado-borne missile speed, flight distance and flight height to be used for safety design of a nuclear power plant. In the method, the authors employed Fujita's DBT-77 model as a tornado wind model to take the near-ground tornado wind profile into account. A liftoff model of an object on the ground was developed by conservatively modeling the lift force due to ground effect. The wind field model and the liftoff model have been compiled together with a conventional flight model into a computer code, named TONBOS. In this study, especially, the code is verified for one- and two-dimensional free-fall problems as well as a case of 1957 Dallas tornado wind field model, whose solutions are theoretically or numerically known. Finally, the code is validated by typical car behaviors characterized by tornado wind speeds of the enhanced Fujita scale, as well as by an actual event where a truck was blown away by a tornado which struck a part of the town of Saroma, Hokkaido in November, 2006.

著者

中島徳行 著

出版者

金の星社

巻号頁・発行日

vol.1, 1942

著者

竹上 弘彰 高松 邦吉 伊藤 主税 日野 竜太郎 鈴木 敬一 大沼 寛 奥村 忠彦

出版者

Atomic Energy Society of Japan

雑誌

日本原子力学会和文論文誌 (ISSN:13472879)

巻号頁・発行日

vol.13, no.1, pp.7-16, 2014

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One of the important problems in the control of the Fukushima Daiichi Nuclear Power Plant is the removal of fuel debris. As preparation, a nondestructive inspection method for identifying the position of fuel debris is required. Therefore, we focused on a nondestructive inspection method using cosmic-ray muons, which is utilized for ground investigation. In this study, the applicability of this method for internal visualization of the reactor was confirmed by a preliminary test of the internal visualization of the High-Temperature Engineering Test Reactor (HTTR) of Japan Atomic Energy Agency. By using cosmic-ray muons, main components in the HTTR reactor, such as concrete walls and the reactor core, can be observed from the outside of the containment vessel of the HTTR. From the results of the preliminary examination, it appears that the inspection method with muons is promising for searching for fuel debris in a reactor. Based on the results, we also proposed some improvements of this system for its application to inspection at the Fukushima Daiichi Nuclear Power Station.<br>

著者

中村初枝 等編

出版者

九州聯合第二回馬匹第一回畜産共進会協賛会

巻号頁・発行日

vol.上巻, 1913

著者

木場 紗綾

出版者

京都大学

雑誌

東南アジア研究 (ISSN:05638682)

巻号頁・発行日

vol.52, no.2, pp.348-350, 2015-01-31

著者

鈴木 翔

出版者

不明

雑誌

日本教育社会学会大会発表要旨集録

巻号頁・発行日

no.62, pp.196-197, 2010

著者

山田 勝

出版者

松蔭女子学院大学学術研究会

雑誌

Shoin literary review (ISSN:02886154)

巻号頁・発行日

vol.1, pp.71-90, 1968-12-28

著者

三村 英也 伊藤 周史 寺島 万成 長島 圭士郎 内藤 健晴

出版者

一般社団法人 日本アレルギー学会

雑誌

アレルギー

巻号頁・発行日

vol.59, no.3, 2010

著者

黒田 和明

出版者

一般社団法人日本物理学会

雑誌

日本物理學會誌 (ISSN:00290181)

巻号頁・発行日

vol.52, no.10, pp.752-758, 1997-10-05

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万有引力定数は, 基礎物理定数の中で最も測定精度の低い定数である. その精度の改善は他の定数に比べるとひときわのんびりと進められてきたが, 3年前に三つの異なるグループから大きく食い違う結果が公表されて以来, 各地で測定への取り組みが活発化してきた. 現在の定数値に潜む誤差への著者の指摘も紹介しながら, この定数の素顔に迫る.

著者

久保田 信

出版者

NPO法人 環境市民

雑誌

<環境市民マガジン> 流れを変える

巻号頁・発行日

vol.7, pp.26-27, 2015-02

著者

金井 壽宏

出版者

神戸大学

雑誌

國民經濟雜誌 (ISSN:03873129)

巻号頁・発行日

vol.195, no.2, pp.43-64, 2007-02

著者

ドイツ労働戦線本部社会局 編

出版者

栗田書店

巻号頁・発行日

1940

著者

相原 玲二 藤田 貴大 前田 香織 野村 嘉洋

出版者

一般社団法人情報処理学会

雑誌

情報処理学会論文誌 (ISSN:18827764)

巻号頁・発行日

vol.43, no.12, pp.3889-3897, 2002-12-15

被引用文献数

36

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本論文では,ノードがネットワークを越えて移動しても同一アドレスを使用して通信を開始・継続することができる,インターネット上の新たなアーキテクチャとして,Mobile IP with Address Translation(MAT)を提案する.移動透過性実現のため,MATではノードを識別するIPアドレスを,ノード識別子と位置指示子に区別して扱い,両者をIP Address Mapping Server(IMS)により対応づける.通信相手がMAT対応ノードか否か(アドレス変換の要/不要)の判断およびIMSの探索にはDNSを用いる.MATはIPv4,IPv6いずれにも対応でき,きわめて多数のノードが移動ノードとなる場合にも対応できる.本論文ではMATアーキテクチャについて述べ,プロトタイプ実装および評価などにより,MATは許容できるオーバヘッドで移動透過性を実現可能であることを示す.In this paper,we propose a new architecture providing mobility support in the Internet,called Mobile IP with Address Translation (MAT).Mobility support means that communications to/from a mobile node can be started and continued without changing its IP address whenever the node moves through networks.To realize mobility support,a node supporting MAT has two IP addresses corresponding to a node identifier and a locator of the node.These two addresses are mapped by an IP Address Mapping Server (IMS).We use the Internet DNS to distinguish whether a node is supporting MAT or not,and to search IMSs.MAT can be applied to both IPv4 and IPv6,and has an advantage in the case that there are many mobile nodes.We describe MAT architecture and show mobility support of MAT by implementation of a prototype system and its evaluations.