著者

Akira YABUKI Keijiro MIZUKAMI Satoshi TOKUNAGA Osamu YAMATO

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.15-0404, (Released:2015-08-08)

被引用文献数

2

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Ghrelin is a peptide hormone that is mainly produced by the stomach. The kidney is a major source of local ghrelin, and maintaining body fluid balance is considered a critical role of renal ghrelin. However, there are no reports on ghrelin in small animal medicine. The present study investigated the intrarenal localization of and change in ghrelin expression in dogs with immune complex-mediated glomerulonephritis (ICGN). Ghrelin immunoreactivity (IR) was observed in the distal tubules of normal kidneys. Ghrelin IR was weak in ICGN kidneys and the quantitative ghrelin IR score was significantly lower in ICGN kidneys than in normal kidneys. In cases of ICGN, plasma creatinine concentrations showed a positive correlation with the ghrelin IR score.

著者

Chunqiu LI Shan WEI Donghua GUO Zhihui WANG Yufei GENG Enyu WANG Xiwen ZHAO Mingjun SU Xinyu WANG Dongbo SUN

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.15-0414, (Released:2015-08-07)

被引用文献数

2 25

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Canine kobuviruses (CaKVs) are newly recognized picornaviruses that have been recently detected in dogs in the USA, Italy, UK, the Republic of Korea and Tanzania. To trace the evolution of CaKV strains, a total of 201 fecal samples from rectal swabs of diarrheic dogs, which were obtained from May 2014 to April 2015 in northeast China, were detected by reverse transcription-PCR targeting a partial (504 bp) fragment of the 3D gene. Furthermore, a phylogenetic analysis of the CaKV strains identified in northeast China was conducted based on the partial 3D gene sequence. The results indicated that 36 fecal samples (17.91%, 36/201) were positive for CaKV, in which the co-infection rates of canine coronavirus, canine parvovirus-2 and canine bocavirus were 58.33%, 41.67%, and 11.11%, respectively. Sequence comparison of the partial 3D gene revealed nucleotide homologies of 94.4–100%, 95.6–98.6%, 94.3–97.6%, 94.4–96.3% and 93.3–95.1% within the 36 Chinese CaKV strains, and between the 36 Chinese CaKV strains and four CaKV reference strains from South Korea, Italy, USA and Tanzania, respectively. A phylogenetic tree revealed that the 36 Chinese CaKV strains formed one specific CaKV lineage with CaKVs that have recently been identified in other countries. The 36 Chinese CaKV strains were closely related to CaKV reference strains from Asia and Europe, but differed genetically from CaKV reference strains from North America and Africa. This study provides evidence that CaKVs circulate in diarrhoetic dogs in China and that they exhibit substantial genetic diversity and high co-infection rates with other enteric viruses.

著者

佐藤 賢治

出版者

仙台市科学館

雑誌

仙台市科学館研究報告 (ISSN:13450859)

巻号頁・発行日

no.25, 2015-07-29

著者

Bandula Kumara WICKRAMASEKARA RAJAPAKSHAGE Janaka Pradeep Kumara ELLEARAEWE GARUHAMILAGE Dona Daphney Niranjala DE SILVA Ashoka DANGOLLA

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.15-0209, (Released:2015-08-03)

被引用文献数

3

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The purpose of this prospective study was to establish the ultrasonographic characteristics of the dimension of the right pancreatic lobe with that of the associated anatomic landmarks in healthy dogs. Ultrasonographic examinations were performed on 25 dogs. The thickness of the right pancreatic lobe was compared with that of mural thickness of duodenum, diameters of duodenum, pancreatic duct, abdominal aorta, portal vein, caudal vena cava, and length and width of the right kidney and right adrenal gland. The correlation between each pancreatic parameter and the dimensions of the anatomical landmarks were assessed using linear regression analysis and Pearson’s correlation coefficient (r) test. Significant, but weak linear correlations were observed between thickness of right pancreatic lobe with that of duodenum mural thickness (r=0.605, R2=0.339, P=0.001); duodenum diameter (r=0.573, R2=0.299, P=0.003); and right adrenal gland length (r=0.508, R2=0.052, P=0.01). There was no significant dimensional relationship with other selected anatomic landmarks. The ratio between the thickness of right pancreatic lobe and the mural thickness of duodenum, diameter of duodenum and length of right adrenal gland were 2.88 ± 0.53, 1.27 ± 0.27, and 0.81 ± 0.15, respectively. Calculating the ratio of thickness of the right pancreatic lobe with the dimension of significantly correlated anatomic landmarks is a useful and simple method for evaluating the size of the right pancreatic lobe in dogs in clinical practice.

著者

足立 幸子

出版者

人文科教育学会

雑誌

人文科教育研究 (ISSN:09131434)

巻号頁・発行日

no.24, pp.41-51, 1997-08-20

著者

大蔵省印刷局 [編]

出版者

日本マイクロ写真

巻号頁・発行日

vol.1927年05月09日, 1927-05-09

著者

松山 あゆみ

出版者

京都大学大学院人間・環境学研究科現代文明論講座文明構造論分野道簱泰三研究室

雑誌

文明構造論 : 京都大学大学院人間・環境学研究科現代文明論講座文明構造論分野論集 (ISSN:18804152)

巻号頁・発行日

vol.6, pp.35-53, 2010-09-07

著者

大蔵省印刷局 [編]

出版者

日本マイクロ写真

巻号頁・発行日

vol.1941年12月06日, 1941-12-06

著者

藤瀬 守正 櫨山 藩 渡辺 吉之 水島 光男

出版者

日本航空宇宙学会

雑誌

日本航空宇宙学会誌 = Journal of the Japan Society for Aeronautical and Space Sciences (ISSN:00214663)

巻号頁・発行日

vol.48, no.555, pp.257-259, 2000-04-05

著者

板津 裕己

出版者

一般社団法人 日本教育心理学会

雑誌

教育心理学研究 (ISSN:00215015)

巻号頁・発行日

vol.42, no.1, pp.86-94, 1994-03-30 (Released:2013-02-19)

参考文献数

20

被引用文献数

1

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The aim of this study was to investigate the relation between self-acceptance and interpersonal attitude. Self-acceptance was measured with Self Acceptance Scale (SASSV, Itatsu, 1989, 1993), and interpersonal attitude was done with Interperso nal Attitude Inventory (IAI, Kato & Takagi, 1980) and Interpersonal Relations Inventory (IRI, Fukuyama, 1981). Subjects were 391 male university students. Close relationships were found between many subscales and indices of SASSV, and subscales on IAI and IRI. Every subscale and Basic Trait (Secondary Factor) on SASSV had a close relation with different aspect on interpersonal attitude. Subjects who accepted their own self had a friendly attitude toward others. From the results mentioned above, a hypothesis was built up willing that each trait or factor of self-acceptance had a close relation with specific aspect on interpersonal attitude. DBS (Distance Balance Score), which was one of the indices of SASSV, was related to discrepancy sc ores on IRI. This result meant that inner balance of self-acceptance contributed to disparity between self-attitude and attitude for others.

著者

古橋知大 大村廉

雑誌

マルチメディア、分散協調とモバイルシンポジウム2014論文集

巻号頁・発行日

vol.2014, pp.138-143, 2014-07-02

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看護や介護において,ベッド上での患者の状態を把握することは非常に重要である.例えば,ベッド上で長時間同じ姿勢でいることは褥瘡を発生させる原因となり,一日のうち長時間をベッド上で過ごさなければならない患者にとって非常に大きな問題となる.また,医療の質の向上には,ベッド上での異常な動きの検出による迅速な対応や,患者の動作の支援などが必要不可欠である.本研究では,Microsoft Kinectセンサを用いて患者の姿勢を取得するシステムの開発を行い,医療分野へ応用していくことを目的とする.本システムでは外れ値にロバストなモデルフィッティング手法として知られるRANSAC法(Random Sampling Consensus)によってベッド平面を推定し,距離画像から除去して,そこから人体認識を行う手法を提案し,ベッド上の患者の姿勢を取得する手法を提案する.実装したシステムについて,4名の被験者を対象に,仰臥位,側臥位,腹臥位の姿勢で実験を行った.出力から,すべての姿勢においてベッド平面の推定,除去,人体骨格の抽出に成功したことを確認した.

著者

等々力 心太朗 原田 泰

出版者

一般社団法人 日本デザイン学会

雑誌

日本デザイン学会研究発表大会概要集 日本デザイン学会 第57回研究発表大会

巻号頁・発行日

pp.A13, 2010 (Released:2010-06-15)

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この研究は、リアルタイムドキュメンテーション(以下RTD)のスムーズでクオリティの高い活動を目指している。本研究は、特に紙媒体による表現に主眼を置いている。その目的は、リアルタイムペーパー(以下RTP、参加者がその場で持って帰ることのできる新聞)の表現や制作、記録のノウハウを外在化することである。その研究の一環として、RTDのスタッフやファシリテータとのイメージの共有を目指して、これまでにRTDの活動にて作成されたRTPの分類を行った。その結果、以下のパターンがあげられた。 1.グリッド型 2.チャート型 3.コラム単位型 4.レイヤー構造型 5.マップ型

著者

Keisuke Yanagisawa Takashi Ishida Yutaka Akiyama

出版者

一般社団法人 情報処理学会

雑誌

IPSJ Transactions on Bioinformatics (ISSN:18826679)

巻号頁・発行日

vol.8, pp.21-27, 2015 (Released:2015-08-19)

参考文献数

21

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It is necessary to confirm that a new drug can be appropriately cleared from the human body. However, checking the clearance pathway of a drug in the human body requires clinical trials, and therefore requires large cost. Thus, computational methods for drug clearance pathway prediction have been studied. The proposed prediction methods developed previously were based on a supervised learning algorithm, which requires clearance pathway information for all drugs in a training set as input labels. However, these data are often insufficient in its numbers because of the high cost of their acquisition. In this paper, we propose a new drug clearance pathway prediction method based on semi-supervised learning, which can use not only labeled data but also unlabeled data. We evaluated the effectiveness of our method, focusing on the cytochrome P450 2C19 enzyme, which is involved in one of the major clearance pathways.

著者

Nobuaki Yasuo Masakazu Sekijima

出版者

一般社団法人 情報処理学会

雑誌

IPSJ Transactions on Bioinformatics (ISSN:18826679)

巻号頁・発行日

vol.8, pp.9-13, 2015 (Released:2015-07-08)

参考文献数

25

被引用文献数

1

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We developed a new application to quantitatively evaluate the sequence conservation of ligand-binding sites by integrating information pertaining to protein structures, ligand-binding sites, and amino acid sequences. These data are visualized onto protein structures via a Jmol or PyMOL interface. The visualization is very important for structure-based drug design (SBDD). Key features of this application are the visualization of slight differences in specific ligand-binding sites and ConservationScore comparable among ligand-binding sites. Furthermore, we conducted an experiment to visualize the calculation and comparison of the ConservationScore of four viral proteins as well as an experiment to visualize the differences between proteins belonging to the human β adrenergic receptor family. This application is available at http://www.bio.gsic.titech.ac.jp/visco.html.

著者

井垣 章二 イガキ ショウジ Igaki Shoji

出版者

同志社大学人文学会

雑誌

人文學 = Doshisha University Jinbungaku (Studies in Humanities) (ISSN:04477340)

巻号頁・発行日

no.42, pp.109-120, 1959-05-25

著者

山本 明 ヤマモト アキラ Yamamoto Akira

出版者

同志社大学人文学会

雑誌

人文學 = Doshisha University Jinbungaku (Studies in Humanities) (ISSN:04477340)

巻号頁・発行日

no.34, pp.81-95, 1958-03-10

著者

大蔵省印刷局 [編]

出版者

日本マイクロ写真

巻号頁・発行日

vol.1937年11月20日, 1937-11-20

著者

永井 滋郎

出版者

日本西洋古典学会

雑誌

西洋古典學研究 (ISSN:04479114)

巻号頁・発行日

vol.15, pp.52-62, 1967-03-23

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It is the object of the present article to analyze and understand the characteristics of peace consciousness of Polybius who lived in the Hellenistic age of chronic wars and wrote a world history in the true sense. We can see in his book, especially in IV. 31. 3-8 and IV. 74. 3, what kind of attitude he took toward the problem of peace. There he wrote as follows: "That war is a terrible thing I agree, but it is not so terrible that we should submit to anything in order to avoid it. ......Peace indeed, with justice and honour is the fairest and most profitable of possessions, but when joined with baseness and disgraceful cowardice, nothing is more infamous and hurtful." Thus, Polybius insisted that liberty and justice were indispensable conditions for peace. We can also recognize the same idea of connecting peace with liberty and justice in many other Greek politicians and historians such as Thucydides. The Greek thought of peace, however, was metamorphosed gradually by historical conditions in the development of the ancient world. Thucydides advocated the war for justice and took a rather aggressive attitude against other city-states such as Sparta, putting stress on Athenian hegemony, although he admitted that peace was naturally desirable. His conception of peace could never depart far from the narrow idea of ομονοια within a πολι&b.sigmav;. The Greek idea of peace was widened by Isocrates to Panhellenistic homonoia, but he had a strong antagonism against Barbaroi. In the historical development of peace theory, the Hellenistic age played a very important role, giving birth to the cosmopolitan pacifism. This kind of pacifism, however, could not become a historical force to attain world peace, because it had a tendency to escape from reality. Though Polybius was influenced by Stoicism he was able to reach a sort of realistic pacifism and wanted to cooperate with Rome, cherishing the idea of a united and organic world consisting of the cultural Hellas and the political Rome, where the common freedom of Hellas should be fundamentally respected. Moreover, he evaluated highly the value of unions of city-states such as the Achaean league. He had not merely a Stoic, philosophic and abstract idea of cosmopolitanism, but a positive, ego-involving and realistic attitude of international cooperation. Thus, the freedom of Hellas as a condition of peace was connected by him with a kind of internationalism and with a Hellenistic idea of one organic world founded on the principle of equality among races and nations. In this sense, we may recognize that Polybius was indeed a pioneer of realistic pacifism, that is of internationalism, though of course in an ancient pattern, which has its limitations for us. It was regrettable after all that the ancient world could not develop this kind of pacifism, but had to seek for a key to solve its problems in Pax Romana and eventually in Pax Dei.

著者

AKIMOTO Daisuke

雑誌

Ritsumeikan Journal of Asia Pacific Studies

巻号頁・発行日

no.31, pp.120-132, 2012-11

著者

Akimoto Daisuke

出版者

創価大学平和問題研究所

雑誌

創大平和研究 (ISSN:03876209)

巻号頁・発行日

no.26, pp.27-53, 2011