著者
Yi-Hao Ho Yue-Cune Chang Wei-Cheng Huang Hsin-Yi Chen Che-Chen Lin Fung-Chang Sung
出版者
日本疫学会
雑誌
Journal of Epidemiology (ISSN:09175040)
巻号頁・発行日
pp.JE20140051, (Released:2014-08-23)
参考文献数
24
被引用文献数
2 5

Background: To date, the relationship between zolpidem use and subsequent risk of glaucoma in a Taiwanese population has not been assessed.Methods: We used data from the National Health Insurance system to investigate whether zolpidem use was related to glaucoma risk. A 1:4 matched case-control study was conducted. The cases were patients newly diagnosed with glaucoma from 2001 to 2010. The controls were randomly selected non-glaucoma subjects matched by sex and age (±5 years). Zolpidem exposure and/or the average dosage of zolpidem used (mg/year) were evaluated. Medical comorbidities were considered as confounding factors. Multiple logistic regression models were used to evaluate the potential risk of zolpidem exposure on glaucoma with/without adjustment for the effects of confounding variables.Results: The exposure rate of zolpidem use in the glaucoma group was significantly higher than that of the control group (2.8% vs. 2.0%, P < 0.0001). The adjusted odds ratio (OR) of the risk of glaucoma for those with zolpidem use vs. those without was 1.19 (95% confidence interval [CI], 1.02–1.38). Compared to non-zolpidem users, zolpidem users with an average dose of more than 200 mg/year had significantly increased risk of glaucoma (OR 1.31, 95% CI 1.03–1.68).Conclusions: This study suggests that the use of zolpidem might increase the risk of subsequent glaucoma. Further confirmatory studies are recommended to clarify this important issue.
著者
瀬川 文徳 黒岩 義之
出版者
一般社団法人 日本内科学会
雑誌
日本内科学会雑誌 (ISSN:00215384)
巻号頁・発行日
vol.89, no.4, pp.608-616, 2000-04-10 (Released:2008-06-12)
参考文献数
5

不随意運動は,主にその運動の出現が安静時か動作・姿勢時か,律動性の有無,運動の速さ,律動性があれば動きの周波数に注目し分類していくことが有用である.近年,基底核の神経回路への知見の集積とともに,錐体外路性の不随意運動に対する新たな理解が深まり,不随意運動などの運動異常に対して,定位脳手衛や電気刺激療法も行われるようになってきた.近年の基底核回路への考え方を図示し,不随意運動の病態,分類について解説する.
著者
Kazuya KUSHIDA Urs GIGER Toshihiko TSUSUI Megumi INABA Yoshio KONNO Kureha HAYASHI Kana NOGUCHI Akira YABUKI Keijiro MIZUKAMI Moeko KOHYAMA Yasuyuki ENDO Osamu YAMATO
出版者
公益社団法人 日本獣医学会
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
pp.14-0600, (Released:2015-02-13)
被引用文献数
6

Erythrocyte pyruvate kinase (PK) deficiency is an inherited glycolytic erythroenzymopathy caused by mutations of the PKLR gene. A causative mutation of the feline PKLR gene was originally identified in Abyssinian and Somali cats in the U.S.A. In the present study, a TaqMan probe-based real-time PCR genotyping assay was developed and evaluated for rapid genotyping and large-scale screening for this mutation. Furthermore, a genotyping survey was carried out in a population of four popular purebred cats in Japan to determine the current mutant allele frequency. The assay clearly displayed all genotypes of feline PK deficiency, indicating its suitability for large-scale survey as well as diagnosis. The survey demonstrated that the mutant allele frequency in Abyssinian and Somali cats was high enough to warrant measures to control and prevent the disease. The mutant allele frequency was relatively low in Bengal and American shorthair cats; however, the testing should still be carried out to prevent the spread of the disease. In addition, PK deficiency should always be considered in the differential diagnosis of anemia in purebred cats in Japan as well as worldwide.

1 0 0 0 平泉の鎮守

著者
前川 佳代
出版者
学術雑誌目次速報データベース由来
雑誌
古代文化 (ISSN:00459232)
巻号頁・発行日
vol.45, no.9, pp.47-56,60, 1993
著者
金井 猛志 岡本 龍一 ファリス ヒシャム 桑村 有司 山田 実
出版者
一般社団法人電子情報通信学会
雑誌
電子情報通信学会技術研究報告. LQE, レーザ・量子エレクトロニクス (ISSN:09135685)
巻号頁・発行日
vol.108, no.51, pp.1-6, 2008-05-16
被引用文献数
2

高屈折率導波路と真空中を走行する電子を利用した新しい光発生法を実験的に検証した.高屈折率導波路を利用して導波モードの位相速度ν_<opt>を光速cの1/3程度まで遅くしておき、電子の群速度ν_eを導波モードの位相速度で走行させると、一種のチェレンコフ放射により導波路から放射光が発生する.実験では、真空/Si薄膜/SiO2から構成されるスラブ導波路を利用した.導波路表面の真空領域には導波モードのエベネッセント電界がしみだしている.この導波路表面に沿って、32KVから42KVに加速した電子を走行させた時、導波路出力端からTM偏光の放射光が観測された.加速電圧の増加と共に、その発光のピーク波長は、1.2μmから1.6μmまで変化した.その発光波長は、ν_e=ν_<opt>から求まる条件と一致し、我々の原理に基づく発光である事が実証された.また、放射スペクトルの形状から真空中の電子波動のコーヒレント長の推定を行った.
著者
伊藤 綾子 渡辺 康 中島 正博
出版者
マイコトキシン研究会
雑誌
マイコトキシン (ISSN:02851466)
巻号頁・発行日
vol.58, no.1, pp.7-13, 2008-01-31
被引用文献数
1

チョコレート中のアフラトキシン(アフラトキシンB<sub>1</sub>, B<sub>2</sub>, G<sub>1</sub>, G<sub>2</sub>;AFs)分析法を確立し、室内再現精度の確認を実施した。チョコレート中のAFsは、アセトニトリル-メタノール-水(60+10+40, v/v/v)で抽出し、イムノアフィニティカラムにより精製後、蛍光検出HPLCにて定量を行った。試料にAFs標準液を0.1および10.0 μg/kgの濃度となるように添加し、日内および日間における繰り返し試験を行った結果、全てのAFsにおける回収率は90-97 %、併行再現性の相対標準偏差は1.7-3.3 %、日間再現性の相対標準偏差は0-4.1 %、異日分析における室内再現性の相対標準偏差に対するHorRatは、全て0.2以内であった。以上の結果から、チョコレート中のAFsは本法により精度良く分析できる事が確認された。
著者
鈴木 覚 後藤 義明 北村 兼三 高梨 聡 岡野 通明 野口 宏典 大谷 義一 坂本 知己
出版者
日本森林学会
雑誌
日本森林学会誌 (ISSN:13498509)
巻号頁・発行日
vol.95, no.1, pp.32-36, 2013

平成24年5月6日に茨城県常総市からつくば市にかけて竜巻が発生した。つくば市山木地区と平沢地区の森林被害を調査した。平沢地区の標高50∼130 mの斜面に, 直径250∼300 mの円形の被害発生領域がみられ, この円形領域で竜巻が消滅したと考えられた。この竜巻が消滅した地点を除き, 次の特徴がみられた。 (1) 壊滅的な被害は100 m前後の幅で発生し, これは竜巻のスケールを反映していると考えられた。 (2) 広葉樹を主体とした森林や強風被害を受けにくい条件を備えた森林とも壊滅的な被害を受けたことから, ひとたび竜巻の経路にあたれば, 林況にかかわらず壊滅的な被害が生じると考えられた。 (3) 倒木は竜巻経路の中心に向かって倒れる傾向がみられた。これは竜巻による強風の特徴である風の収束を反映していると考えられた。
著者
今泉 吉典 吉行 瑞子
出版者
THE MAMMAL SOCIETY OF JAPAN
雑誌
哺乳動物学雑誌: The Journal of the Mammalogical Society of Japan (ISSN:05460670)
巻号頁・発行日
vol.2, no.4, pp.105-108, 1965

A specimen, subadult female, of <I>Tadarida</I> was collected from Kumamoto City, Kyushu, Japan, by Dr. H. Tange in April, 1964. It is identified as <I>T. insignis</I> (BLYTH, 1861) and hence the third record for this species in Japan. If this identification is correct, <I>insignis</I> may not be a subspecies of <I>T. teniotis</I> but a distinct species differing in the following characters; 1) the wing membranes are only inserted to the lower third of the tibia instead of just above the ankle; 2) calcar with a distinct keel; 3) color of fur is fuscous, much darker than that of <I>teniotis</I>; 4) in the skull, zygomatic and lachrymal breadth are relatively narrower and the mandible is relatively longer than in <I>teniotis</I>; 5) lower incisors are strongly imbricated and the relatively larger second incisor extends to the middle of the inner lobe of the first incisor. The distribution of <I>insignis</I> is confined to China, Korea, southern Ussuri and Japan and clearly separated from that of <I>teniotis</I> by a broad region extending from Indo China and Tibet to Afghanistan.
著者
今泉 吉典
出版者
THE MAMMAL SOCIETY OF JAPAN
雑誌
哺乳動物学雑誌: The Journal of the Mammalogical Society of Japan (ISSN:05460670)
巻号頁・発行日
vol.5, no.2, pp.76-79, 1970

Correlations between mean values of tail length in respective local populations of <I>Dymecodon pilirostris</I> and medial latitudes of localities of the latters revealed the presence of two distinct linear clines among them (Fig. 2) . The mean values of tail length in respective populations belonging to the clines can then be expressed by a formula <I>Y<SUB>c</SUB>=a+bX</I>. As 'a' and 'b' remain always constant in any population within a cline, it may be reasonable to conclude that such populations differ one another only phenetically at least in this character and may constitute a single taxon as there are no other differences discovered among them. The 'a' and 'b' values, however, are evidently different in accordance with clines and probably with degrees of evolution of the group. So that a cline of this kind seems to represent a 'lineage' of the author's concept which is equivalent both to the species and subspecies of the most of authors. A specimen recently discovered by the Crown Prince of Japan from Mt. Asama, Central Honshu, obviously belongs to the lineage B composed by Shiga, Nikko, Zao, Goyo and Hayachine populations. This lineage is characterized by relatively shorter then probaly more progressed tail than that of the lineage A which contains populations from Fuji, Minami Alps, Chichibu, Yatsugatake and Kita Alps and has relatively longer and primitive tail.
著者
今泉 吉典
出版者
THE MAMMAL SOCIETY OF JAPAN
雑誌
哺乳動物学雑誌: The Journal of the Mammalogical Society of Japan (ISSN:05460670)
巻号頁・発行日
vol.5, no.2, pp.62-66, 1970
被引用文献数
1

Similarity relationships of <I>Canis hodophilax</I> TEMMINCK, 1839, among 20 species and subspecies of the genus <I>Canis</I> were investigated based on appearance ratios of 30 cranial characters (Table 1) . The result was that <I>hodophilax</I> may not be a subspecies of <I>lupus</I> against to opinions of the most of modern authors but a distinct species well differentiated from any other forms of the genus (Fig. 1) . Emarginated anterior border of mesopterygoid fossa, great distance between jugal and glenoid fossa, distinctly internal lachrymal formen and frequently divided anterior opening of alisphenoid canal are characters rather common to this species but rarely found in the other forms of the genus.
著者
今泉 吉典
出版者
THE MAMMAL SOCIETY OF JAPAN
雑誌
哺乳動物学雑誌: The Journal of the Mammalogical Society of Japan (ISSN:05460670)
巻号頁・発行日
vol.6, no.3, pp.127-136, 1975

<I>Lutronectes whiteleyi</I> GRAY, 1867, based on two young specimens collected from Hakodate, Hokkaido, Japan, seems to be extinct in the native land, and no specimens have been known in Japan.<BR>While studying the river otter of Japan, the author was attracted his attention by an adult rough skeleton of the subgenus <I>Lutra</I> in the mammal collection of the National Science Museum, Tokyo. Unfortunately the locality of the specimen is uncertain, but there is little doubt that it was collected at the beginning of the Mei ji era, nearly 100 years ago, in the territory of Japan at that time, that is Hondo or Hokkaido. As the specimen is evidently different from the otter of Hondo, the locality is inevitably estimated as Hokkaido.<BR>This estimation coincides with the result of identification of the specimen as <I>Lutra whiteleyi</I> based on strong similarities to OGNEV's adult specimen from Nemuro, Hokkaido, and dissimilarities to the most of the named forms of the subgenus <I>Lutra</I>, in several cranial measurements.<BR>If this identification is correct, <I>whiteleyi</I> seems to be a well established taxon of <I>Lutra lutra</I> group characterized by relatively narrow mastoid breadth and shorter muzzle (Table 6, F and G) .<BR>An opinion that <I>whiteleyi</I> covers whole populations of the Japanese otter, proposed by Pococx (1931), the present author (1949), etc., is not correct. <I>L. whiteleyi</I> must be confined to the Hokkaido population.
著者
今泉 吉典
出版者
THE MAMMAL SOCIETY OF JAPAN
雑誌
哺乳動物学雑誌: The Journal of the Mammalogical Society of Japan (ISSN:05460670)
巻号頁・発行日
vol.2, no.5, pp.131-135, 1965

The so-called Fissura palatina of <I>Equus</I>, broadly used in the veterinary anatomy, is undoubtedly homologous with the Foramen incisivum of <I>Homo sapiens</I>. The latter seems to be derived from the pared incisive foramina of the lower Primates by reduction of the size of the incisive foramina and reduction of the palatine processes between the foramina and the Fissura palatina of <I>Equus</I> by an enormous development of the processes. Therefore the Fissura palatina of <I>Equus</I> must be strictly called Foramen incisivum. On the other hand, the so-called Foramen incisivum of <I>Equus</I> is a quite different structure and has no concern with the same named foramen of human anatomy. Therefore, the author wants to designate such a foramen between the medial border of the palatal portion of the premaxillaries as Foramen intermaxillare. Such a small foramen is not infrequently found in <I>Mogera, Microtus, Rattus</I>, and etc. An enormous foramen, posterior to Foramen incisivum, found in Ursidae-and some Mustelidae, is also considered to be Foramen intermaxillare, because it is bordered completely by the palatal process of the premaxillaries.
著者
今泉 吉典 吉行 瑞子 小原 巖 土屋 公幸 今泉 忠明
出版者
THE MAMMAL SOCIETY OF JAPAN
雑誌
哺乳動物学雑誌: The Journal of the Mammalogical Society of Japan (ISSN:05460670)
巻号頁・発行日
vol.4, no.3, pp.63-73, 1969
被引用文献数
1

Three distinct mammal communities were recognized in a forest region on the western slope of Mt. Fuji, Honshu, Japan. Among them, the subalpine conifer forest community is relatively poor both in the number of species and in the density of populations of small mammals and is distinguished from the subalpine deciduous forest community by the absence of <I>Apodemus speciosus speciosus</I> and rarity of <I>Eothenomys kageus</I>. The low mountain mixed forest community is characterized by the presence of <I>Urotrichus talpoides hondonis</I> and the absence of <I>Dymecodon pilirostris</I>.<BR>In the most of species found in this region, the habitat range seems to clearly correlate with the nature of forests. However, those of <I>Dymecodon</I> and <I>Urotrichus</I> are exception and seem to be mainly determined by a kind of competition between them.<BR>In the region above Shôjiguchi Ni-gôme, 1, 500-2, 380 m alt., the habitat range of <I>Dymecodon</I> was completely confined to an area above and that of <I>Urotrichus</I> mostly to an area below a line at about 1, 600 m alt. in a mixed forest. However, two specimens of <I>Urotrichus</I> were obtained in the habitat range of <I>Dymecodon</I>, one at 2, 380 m and the other at 1, 670 m alt. This indicates that the habitat ranges of these two species are mostly segregated, but the territory of <I>Dymecodon</I> population is not so exclusive as that of <I>Urotrichus</I> and contains several individuals of the latter. Quite same phenomena of such special segregation between these two species have been known from Mt. Hayachine, Tohoku District, and Mt. Yatsugatake, Central Honshu.<BR>This can be explained clearly by a following hypothesis. There is a "competition by power" between those two shrew-mole species which are nearly related and similar in general habits including the ecological niche but are slightly different in size and physical strength. So that the individuals of the stronger species, <I>Urotrichus</I>, able to successfully maintain their territories against the individuals of the weaker one, <I>Dymecodon</I>, but the reverse is not true. If the population density of the stronger species is nearly in saturation in an area, then the individuals of the weaker species may be completely driven out from there. But, the stronger species probably able to invade rather freely into the range of weaker species and to live on there.<BR>It is probable that <I>Dymecodon</I>, evidently more primitive and older in origin than <I>Urotrichus</I>, had probably covered nearly completely the foot of Mt. Fuji in ancient times. After that <I>Urotrichus</I> had arrived there and gradually drove out <I>Dymecodon</I> from the foot to subalpine region. However in some regions where <I>Urotrichus</I> perhaps had failed to invade by some kinds of barriers, populations of <I>Dymecodon</I> have been maintained well to the present day. A population of <I>Dymecodon</I> at Lake Motosu region, 910m alt., may be such living remnant.
著者
今泉 吉典
出版者
THE MAMMAL SOCIETY OF JAPAN
雑誌
哺乳動物学雑誌: The Journal of the Mammalogical Society of Japan (ISSN:05460670)
巻号頁・発行日
vol.5, no.6, pp.213-223, 1973

The newly proposed method of taxonomic analysis employing the binomial distribution seems to be usefull to clarify the presence of the reproductive isolation among the members of a population from a continuous region. The binomial distribution is always observed in a local population composed of individuals belonging to a single biological species, but not in a false population containing two or more such species. The reason is briefly explained in the following lines.<BR>In a true local population, variation of a morphological character under the influence of several genes generally shows the normal distribution, so that an allelomorphic type refered to the left or the right half of the distribution always appears at the rate of one half. Therefore, all possible combinations of such allelomorphic types of several qualified characters may occur in the population. Each of the qualified characters here used is composed of two allelomorphic types which have an appearance ratio of one to one, and are not correlated to the other characters and independent with sex, age, season, etc.<BR>If the allelomorphic types of each of the qualified characters are expressed by a capital and a small letters, A a, B b, etc., variations in the number of capital letters in each individual of the true population always constitute a binomial distribution following the laws of combination and probability. But, such binomial distribution cannot occur in a false population composed of two or more distinct species, for the individuals are segregated by the reproductive isolation and random distributions of allelomorphic types are greatly disturbed.<BR>Close correlations between the nature of population and the binomial distribution were confirmed in a true population of <I>Clethriononiys bedfordiae</I> from the main island of Hokkaido and in a false population composed of <I>C. sikotanensis</I> and <I>C. rex</I> from Rishiri Island, off Hokkaido.
著者
今泉 吉典
出版者
THE MAMMAL SOCIETY OF JAPAN
雑誌
哺乳動物学雑誌: The Journal of the Mammalogical Society of Japan (ISSN:05460670)
巻号頁・発行日
vol.2, no.1, pp.17-22, 1961

An imperfect body with a complete skull of <I>Crocidura dsinezumi orii</I> Kuroda 1924, was found in a stomach of <I>Trimeresurus okinavensis</I>, which was colleced in July, 1960 by Mr. T. Morita and Dr. K. Koba at Yuwandake, Amami-Oshima, Japan. It is the second and unique specimen of <I>orii</I>, because this form has only been known by a type, a skin and an imperfect skull, collected in 1922 and destroyed by fire in 1945. The second specimen, adult male, is easily distinguished from <I>russula, sodyi, tanakae, thornasi, dsinezumi, umbrina, chisai, shantungensis, watasei</I> and <I>tadae</I> by relatively longer fur of the back (6.0-6.5 mm against 2.5×5.0 mm), decidedly larger claws of manus (2.7 mm against 1.1-1.8 mm), much shorter braincase (nearly circular against oblong), and posteriorly located posterior border of anteorbital foramen and anterior extremity of orbit. Therefore, this form may not be a subspecies of <I>dsinezumi</I> but a distinct species, <I>Crocidura orii</I>, peculiar to the small island.