著者
笹沼 澄子 福迫 陽子
出版者
The Japanese Association of Rehabilitation Medicine
雑誌
リハビリテーション医学 (ISSN:0034351X)
巻号頁・発行日
vol.9, no.2, pp.79-89, 1972-04-18 (Released:2009-10-28)
参考文献数
7
被引用文献数
35 35

The recovery processes of 72 out of the 269 aphasic patients studied in PART I were investigated longitudinally by means of following up the rate (and direction) of the change of each of the five factors obtained in PART I. Measurement was taken of the increase and decrease of the factor scores estimated for each patient at each of the successive re-testings. The length of the follow-up period ranged from one to 32 months after the initial evaluation.Each factor seemed to have its characteristic mode of change in time. Factor 1 (the general factor of language behavior) had a tendency to exhibit subnormal scores in the majority of subjects at the initial evaluation, but to show a greatest possibility of improvement for a longest period of time (1.5 years since onset). The rest of the factors tended to be more variable in the kinds of subjects exhibiting subnormal scores as well as in the rate and degree of improvement. The clinical types of aphasia appeared to serve as a crutial variable in predicting the overall patterns of improvement of the five factors in individual patients.The findings seemed to give a further support for the neuro-physiological interpretation of the five factors suggested in PART I. The necessity of increased specificity in our diagnostic and therapeutic procedures was emphasized, and the possible use of the factor analysis technique for this purpose was reiterated.
著者
永江 和久 田上 美年子 江島 緑
出版者
The Japan Society of Logopedics and Phoniatrics
雑誌
音声言語医学 (ISSN:00302813)
巻号頁・発行日
vol.20, no.3, pp.181-196, 1979-07-25 (Released:2010-06-22)
参考文献数
14

121 stroke patients with the dominant hemispheric lesions were classified by the Minnesota classification of aphasia and investigated with CCT.1) Euphasics (n=10) and aphasics, minimal (n=6) : The small confined lesions to the basal ganglia and the internal capsule were noted.2) Dysarthria (n=10) : The lesions wers small, bilateral and scattered.3) Group 1 (n=30) : The low density areas were found in the basal ganglia, the internal capsule, F3, T1, the supramarginal gyrus etc. No predilection area was found.4) Group 3 (n=6) : The low density areas were definitely found in F3 (Broca's area) and distributed to the surrounding cortical and deeper structures.5) Group 4 (n=6) : The lesions in CCT were small and limited compared with the severity of language disturbance.6) Group 5 (n=15) : The wide spread low density areas including F3, T1, the insula, the supramarginal, the angular gyrus and the deeper structures were recognized.7) Minor A (n=18) : The low density areas of T1 (Wernicke's area) and its surrounding stracture were present.8) Minor B (n=6) : The small low density areas were found in the basal ganglia and/or the internal capsule or the frontal operculum.9) Combined syndromes of Minor A and Group 3 (n=3) : Cases of this group had the syndromes of severely affected oral language comparing written one. The site of the lesions in CT was combination of F3 and T1.10) Others (n=11) : No common site and spread of the lesions in CCT were found.
著者
戸塚 元吉 福迫 陽子 笹沼 澄子
出版者
The Japan Society of Logopedics and Phoniatrics
雑誌
音声言語医学 (ISSN:00302813)
巻号頁・発行日
vol.24, no.4, pp.257-269, 1983-10-25 (Released:2011-01-31)
参考文献数
59

左側脳硬塞による失語症患者69例 (年齢28~81歳) の失語症検査成績と脳のCT所見との関係について, 側面図に投影する方法を用いて集計し, 以下の知見を得た.1.多くの検査項目において側頭葉の関与が大きかった.2.前頭葉と特に密接な関連にあったのは次の下位検査であった.すなわち, 「嚥下機能」, 「軟口蓋の運動性」, 「単音節のくり返し」, 「音韻変化」, 「流暢性」である.また側頭葉, 頭頂葉下半部と特に密接な関連が示されたのは「復唱」であった.3.入・出力モダリティーが同じ下位検査であっても, 言語処理の複雑さ, ないしレベルの差異によって脳の関与のしかたが異なっていた.4.検査遂行にあたっての入・出力モダリティーや言語処理の複雑さ, ないしはレベルが異なっているにもかかわらず, その差異が今回の結果に反映されない下位検査も認められた.
著者
福迫 陽子 笹沼 澄子
出版者
The Japan Society of Logopedics and Phoniatrics
雑誌
音声言語医学 (ISSN:00302813)
巻号頁・発行日
vol.19, no.2, pp.174-189, 1978-04-15 (Released:2010-06-22)
参考文献数
22
被引用文献数
1

The purpose of the present investigation was to construct a short test of aphasia on the basis of factor analysis and to examine its clinical usefulness.As a first step, we performed the factor analysis of the test scores obtained from the administration of the long test to 180 consecutive patients, which resulted in the identification of the following factors; F1: Word Comprehension, F2: Language Behavior, F3: Phonological Processing, F4: Motor Functions of Speech Organs, F5: Visuomotor Ability, F6: Numerical Concept, F7: Calculation, and F8: Fluency.Secondly, in accordance with the rules of reducing the size of a test battery without transforming the factor structure of that battery, we reduced 56 subtests in the original version to 16.The test scores of the 180 patients on these 16 subtests, then, were put into another factor analysis. The results showed that the factor structure obtained with the shortened test was highly similar to that obtained with the original, longer battery.Examination of clinical usefulness of the shortened test in terms of its ability 1) to classify the patients into major clinical types and 2) to evaluate their severity levels indicated that the short test is quite similar to the original long test in both of these abilities.On the basis of these findings it was tentatively concluded that the new short test of aphasia was a useful tool for screening aphasic patients in a relatively short period of time (approx. 30 min.) as well as for malting a rough estimation on major clinical types and severity of aphasic impairments.
著者
福迫 陽子 物井 寿子
出版者
The Japan Society of Logopedics and Phoniatrics
雑誌
音声言語医学 (ISSN:00302813)
巻号頁・発行日
vol.25, no.4, pp.308-320, 1984-10-25 (Released:2010-06-22)
参考文献数
68
被引用文献数
4 4

失語症の言語訓練経過を知ることを目的に, 言語症状の変化がプラトーに到達した脳血管障害性失語症患者111例 (全例右利き左脳損傷) について失語症鑑別診断検査 (老研版) の総得点を指標として検討し, 以下の知見を得た.(1) 失語症患者の言語訓練経過, すなわちプラトー到達期間, プラトー到達時総得点, および訓練開始時総得点とプラトー到達時総得点の相関はタイプによって差異が認められた.(2) 言語訓練経過は年齢によって差異が認められた.すなわち, まず, 老年群は壮年群に比べて改善度が小さく, つぎに, タイプ内における年齢差については差の認められるタイプとそうでないタイプが認められた.(3) 改善度は言語訓練開始時期が早いほど大きかったが, プラトー到達期間やプラトー到達時総得点には差が認められなかった.(4) 言語訓練経過と性との間には関係は認められなかった.
著者
堀口 哲生
出版者
日本マーケティング学会
雑誌
マーケティングジャーナル (ISSN:03897265)
巻号頁・発行日
vol.40, no.3, pp.58-66, 2021-01-07 (Released:2021-01-07)
参考文献数
44

国際競争の激化,製品ライフサイクルの短縮化の中で,企業は自らの既存の資源・能力を活用した漸進的な製品イノベーションだけでなく,新しい資源・能力の探索を伴う急進的な製品イノベーションを達成することがますます求められている。しかし,急進的な製品イノベーションには非常に高いリスクや不確実性が伴い,その実現は困難である。その中で,多くのマーケティング・経営学者は,急進的な製品イノベーションを促進・阻害する要因についての研究を行ってきた。とりわけマーケティング学者は,マーケティング組織の活動が,急進的な製品イノベーションを促進・阻害するのかという課題に対して多くの関心を向けてきた。本論の目的は,マーケティング組織の活動と急進的な製品イノベーションの関係について検討した既存研究をレビューし,その知見を整理することである。具体的には,マーケティング組織と急進的な製品イノベーションの関係に着目した2つの研究潮流をレビューした上で,マーケティング組織が急進的な製品イノベーションに如何に関与するべきなのかについて既存研究の知見を整理する。その上で,この研究領域における将来の研究余地を指摘する。
著者
福迫 陽子 物井 寿子
出版者
The Japan Society of Logopedics and Phoniatrics
雑誌
音声言語医学 (ISSN:00302813)
巻号頁・発行日
vol.25, no.4, pp.295-307, 1984-10-25 (Released:2010-06-22)
参考文献数
54
被引用文献数
6 6

失語症の言語訓練経過を知ることを目的に, 脳血管障害性失語症患者275例 (全例右利き左脳損傷) について失語症鑑別診断検査 (老研版) の総得点を指標として検討し, 以下の知見を得た.(1) 失語症の言語訓練経過はタイプによって差異が認められた.(3) タイプ内における言語訓練経過には, 老年群と壮年群の間で差異が認められるタイプと, そうでないタイプがあった.(3) 言語訓練に伴って症状の変化が認められる期間は, 発症後18カ月以内が多かったが, タイプや年齢によって異なり, また個人差も認められた.(4) 言語訓練を中断した症例では, 中断前後で改善は認められなかった.(5) 再発作・手術例では, 再発作・手術後, 全例で失語症状は悪化し, またタイプもより重篤なタイプへ移る傾向が認められた.
著者
今井 聖
出版者
一般社団法人日本PDA製薬学会
雑誌
日本PDA学術誌 GMPとバリデーション (ISSN:13444891)
巻号頁・発行日
vol.19, no.1, pp.6-14, 2017 (Released:2017-06-13)
参考文献数
1

錠剤の識別性を上げて調剤過誤防止(誤飲防止)を実現する技術として錠剤印刷技術が開発されてからかなりの時間が経過するが,最近では素錠にも印刷できる技術が開発されるようになってきた。しかし,一部の錠剤にのみ印刷が施されるだけでは,調剤過誤防止には不十分で,『世の中のすべての錠剤』に印刷されて初めて本来の目的が達成される。 このため,より『低コスト』で,より『安定的』に,より『多種多様な種類の錠剤』に対応可能な「錠剤生産現場の課題」をも解決することもできる錠剤印刷機が必要となる。 この機会に,フロイント産業は今まで開発してきた錠剤印刷技術を紹介するとともに,「世の中のすべての錠剤に印刷」を施すための「錠剤生産現場の課題」も同時に解決可能な最新の技術(周辺技術含む)を紹介する。 フロイント産業は技術開発を継続し,更なる調剤過誤防止(誤飲防止)などに役立つ技術を提供し続けたい。
著者
高石 清和
出版者
公益社団法人 日本薬学会
雑誌
YAKUGAKU ZASSHI (ISSN:00316903)
巻号頁・発行日
vol.88, no.11, pp.1467-1471, 1968-11-25 (Released:2008-05-30)
参考文献数
12
被引用文献数
7 7

Coumarin (1) and coumaric acid glucoside (2) were isolated from the leaves of Prunus yedoensis MATSUM. (cherry tree). The structure of (2) was proved as o-coumaric acid β-D-glucoside which had been isolated from Melilotus altissima TEUIL. and named melilotoside by C. Charaux. Comparative determination of (1) and (2) in the leaves of cherry tree was made, and it was thereby found that red leaves in autumn contained much more o-coumaric acid glucoside than green leaves in spring, with a very small amount of coumarin in free state throughout the year. It is noteworthy that the deeper the red color of the leaves, the higher the content of o-coumaric acid glucoside. It is also interesting from biosynthetic point of view that both coumarin and anthocyan are synthesized through shikimic acid pathway. It was suggested that the leaves of cherry tree contain a fairly high amount of coumarin in the form of o-coumaric acid glucoside with a very small amount of free coumarin, although Kosuge, Brown, and Soine, have reported that o-coumaric acid glucoside in Melilotus spp. is finally converted into free coumarin.
著者
TORU SOGA
出版者
Japan Association for Nilo-Ethiopian Studies
雑誌
Nilo-Ethiopian Studies (ISSN:1340329X)
巻号頁・発行日
vol.2001, no.7, pp.81-99, 2001 (Released:2006-12-22)
参考文献数
19

This study concerns social change in the Gabra, a peripheral pastoralist group in Kenya, brought about by the 1997 general election. Supporters of an unsuccessful candidate in the nomination process tried to unite the Algana, one of the phratries of the Gabra, against the elected person, who belonged to another phratry, in the election. This paper analyzes the supporters' attempts to mobilize people and unite the phratry, paying attention to their discourse and behavior. By participating in the election, Gabra society greatly changed. This paper also examines social change from two different points: in methods of tiiaiiipulatirig others and the nature of the boundary of the phratry, which suggested the transition of Gabra society from ethnie to modern political-ethnic unit.
著者
Atsushi Hozawa Takumi Hirata Hiroshi Yatsuya Yoshitaka Murakami Shinichi Kuriyama Ichiro Tsuji Daisuke Sugiyama Atsushi Satoh Sachiko Tanaka-Mizuno Katsuyuki Miura Hirotsugu Ueshima Tomonori Okamura
出版者
Japan Epidemiological Association
雑誌
Journal of Epidemiology (ISSN:09175040)
巻号頁・発行日
vol.29, no.12, pp.457-463, 2019-12-05 (Released:2019-12-05)
参考文献数
20
被引用文献数
7 17

Background: We sought to investigate the optimal values of BMI for the lowest risk of all-cause death and whether the optimal BMI differs according to smoking status in large-scale pooled analysis of 13 Japanese cohorts.Methods: Data from 179,987 participants of 13 well-qualified cohort studies conducted throughout Japan were used for our analysis. A cohort-stratified Cox proportional hazard model was used. P values for interactions were calculated based on the cross product of BMI and age, sex, or smoking status.Results: In the entire study population, all-cause mortality risk was lowest when the BMI was 22.0–24.9 kg/m2. This was also the case for selected healthy participants (never smoked, baseline total cholesterol level ≥4.1 mmol/L; the first 5 years of follow-up data were excluded). No effect modification of age, sex, or smoking status was observed. Regardless of their BMI, never smokers always had a lower all-cause mortality risk than did current smokers even with an ideal BMI in terms of mortality risk.Conclusion: A BMI of 22–24.9 kg/m2 correlated with the lowest risk of mortality, regardless of whether all participants or selected healthy participants were analyzed. The fact that smoking was more strongly associated with mortality than obesity emphasizes the urgency for effective anti-smoking programs.
著者
北林 耐
出版者
一般社団法人 日本ゴム協会
雑誌
日本ゴム協会誌 (ISSN:0029022X)
巻号頁・発行日
vol.88, no.9, pp.351-357, 2015 (Released:2015-11-25)
参考文献数
18

Latex allergy (LA) is the allergic reaction triggered by proteins containing in natural rubber latex (NRL) or chemicals in NRL products. The pathophysiology of LA is divided into the immediate type (type I) allergy and the delayed type (type IV) allergy. Majority of LA is the allergic reactions mediated by specific IgE (sIgE) antibodies produced by contacts and exposures to NRL by inhaling the powder in the environments when wearing or removing the gloves made from NRL. Recently, the frequency of immediate type allergy reaction is decreasing, but the delayed type allergy reaction caused by chemical substances added during glove manufacturing is increasing. Allergic contact dermatitis (ACD) caused by thiuram compound (a vulcanization accelerator), is increasing and it is clear that 80% of ACD cases in health care workers are sensitized to this substance. For Diagnosis of LA, a detailed patient interview is the most important and sensitization to NRL is confirmed by a blood test or skin test to show an existence of sIgE antibodies to NRL. Also a positive provocation is useful for diagnosis. Treatment for type I reactions is histamine H1 receptor antagonist or systemic steroids. However, in severe case such as anaphylactic shock, it is necessary to administer adrenaline. In case of type IV reactions, it is important to take local steroids or use moisturizing agents in addition to replace gloves free of vulcanization accelerator.
著者
足立 悦男
出版者
日本文学協会
雑誌
日本文学 (ISSN:03869903)
巻号頁・発行日
vol.36, no.7, pp.32-39, 1987-07-10 (Released:2017-08-01)

これまで書かれてきた多くの短歌教材論は、現実ありのままの情景や心情をそのままに表現したものが短歌である、という考え方にもとづいていたようである。わたしはそこに、かねてから考えていた虚構論(表現行為は現実をこえるという立場からの……)を導入してみた。そのことで短歌教材に対する考え方がだいぶ変わっていくのではないか、という展望のもとに。一つの問題提起として書かせていただいた。