著者
Mieko Sugiura Koichi Shibata Satoshi Saito Yoshiko Nishimura Hiroshi Sakura
出版者
The Japanese Society of Internal Medicine
雑誌
Internal Medicine (ISSN:09182918)
巻号頁・発行日
pp.1619-18, (Released:2019-02-01)
参考文献数
24
被引用文献数
5

A 64-year-old woman with no previous mental illness took a single 500 mg tablet of levofloxacin for cystitis. Two hours later, she developed psychosis with involuntary movement and severe hyperventilation with respiratory alkalosis. Cranial magnetic resonance imaging findings were unremarkable, and an electroencephalogram revealed no epileptiform discharge. Her symptoms improved on the third day after levofloxacin was discontinued. Levofloxacin-associated encephalopathy with psychotic features is a rare adverse event. Disturbance of GABAergic interneurons by levofloxacin may lead to hyperventilation via dysfunction of the brainstem respiratory network. Physicians should be aware of hyperventilation as an additional serious symptom of levofloxacin-associated encephalopathy in acute settings.
著者
Satoshi Kumakura Takashi Nakamichi Nonoka Suzuki Shu Yamakage Ayako Ishikawa Emi Fujikura Satoko Sato Takeshi Aoki Hiroaki Musha Katsuko Kikuchi Tasuku Nagasawa Hiroshi Sato Sadayoshi Ito Mariko Miyazaki
出版者
The Japanese Society of Internal Medicine
雑誌
Internal Medicine (ISSN:09182918)
巻号頁・発行日
pp.2378-18, (Released:2019-02-01)
参考文献数
22
被引用文献数
4

A 66-year-old man was admitted to our hospital because of multiple refractory skin ulcers. Based on his severe systemic arterial calcification and severe calcium-phosphate imbalance due to severe kidney dysfunction, we initially considered calciphylaxis. However, a skin biopsy provided a diagnosis of cholesterol crystal embolization. Although we initiated hemodialysis, steroid treatment, and low-density lipoprotein-cholesterol apheresis, he died of multiple intestinal perforation. An autopsy showed cholesterol crystals occluding multiple organ arterioles. This case suggests that skin ulcers in patients with chronic kidney disease may be an important diagnostic hallmark and may be associated with several serious diseases.
著者
Fujiwara Akira Mizutani Makoto Ono Tamao KAGAMI Hiroshi
出版者
日本家禽学会
雑誌
The journal of poultry science (ISSN:13467395)
巻号頁・発行日
vol.42, no.1, pp.64-69, 2005-01-25
参考文献数
13
被引用文献数
2 4

A black plumage color mutant (BPC) was described in this paper. The BPC quail was a dark colored bird. The chick down feathers on the back and head were black ending with a brown tip. The face and throat were cream-yellow and the ventral surface was a mixture of gray and cream-yellow. The beak and shanks were darkly pigmented but some toes were yellow while others had spotted areas of pigmentation.<BR> When the birds reached to maturity, both males and females had pigmentation, and the feather appearance of dorsal and ventral surface were basically similar. The dorsal feather pattern was similar to that of wild-type except that the wheat-straw shafting was absent. Some of the BPC quails showed small areas of white feather at the junction of the upper and lower beaks and in the throat under the lower beak.<BR> To clarify the mode of inheritance of the BPC characters, mating experiments were performed. The segregation data for F<SUB>1</SUB>, F<SUB>2</SUB> and backcross generations were analyzed. Genetic analysis showed that the BPC was controlled by an autosomal recessive gene. Therefore, a gene symbol &ldquo;<CITE>rb</CITE>&rdquo; was proposed.
著者
Hiroshi SANO
出版者
The Japan Academy
雑誌
Proceedings of the Japan Academy, Series B (ISSN:03862208)
巻号頁・発行日
vol.78, no.10, pp.293-298, 2002 (Released:2006-10-17)
参考文献数
29
被引用文献数
6 14

Jean Baptiste de Lamarck (1744-1829) maintained that characteristics that were acquired during an organism's lifetime are passed on to its offspring. This theory, known as Lamarckian inheritance, was later completely discredited. However, recent progress in epigenetics research suggests it needs to be reexamined in consideration of DNA methylation. In this article, I summarize our observations, which support Lamarckian inheritance. Initial experiments indicate that (1) artificially induced demethy-lation of rice genomic DNA results in heritable dwarfism, and (2) cold stress induces extensive demethy-lation in somatic cells of the maize root. Based on these results, I propose the hypothesis that traits that are acquired during plant growth are sometimes inherited by their progeny through persistent alteration of the DNA methylation status.
著者
Kazutaka Aoki Hiroshi Kamiyama Kiyomi Masuda Kazunari Kamiko Yoshihiko Noguchi Kazuki Tajima Yasuo Terauchi
出版者
The Japan Endocrine Society
雑誌
Endocrine Journal (ISSN:09188959)
巻号頁・発行日
vol.61, no.3, pp.249-256, 2014 (Released:2014-03-30)
参考文献数
35
被引用文献数
5 10

We previously reported that combination therapy with an α-glucosidase inhibitor (αGI) and a dipeptidyl peptidase-4 (DPP-4) inhibitor increased active glucagon-like peptide-1 (GLP-1) levels and decreased total glucose-dependent insulinotropic polypeptide (GIP) levels, compared with monotherapy, in non-diabetic men. However, the peptide YY (PYY), cholecystokinin (CCK), ghrelin, and obestatin levels in patients receiving a combination of αGIs and DPP-4 inhibitors have not been previously reported. We evaluated the effect of miglitol, vildagliptin, or their combination on these parameters. Miglitol and/or vildagliptin were administered according to four different intake schedules in eleven non-diabetic men (C: no drug, M: miglitol; V: vildagliptin, M+V: miglitol+vildagliptin). Blood samples were collected at 0, 30, 60, and 120 min after the start of breakfast. The plasma glucose, serum insulin, serum total PYY (PYY1-36 and PYY3-36), plasma CCK, plasma active ghrelin, and plasma obestatin levels were measured. The area under the curve (AUC) of the serum total PYY level in the M group was significantly greater than that in the C group, and the AUC of the serum total PYY level in the M+V group was significantly lower than that in the M group. The combination therapy did not change the AUC of the plasma CCK, plasma active ghrelin, plasma obestatin, and ghrelin/obestatin levels, compared with the control. The results of our study suggested that combination therapy with miglitol and vildagliptin had no effect on appetite regulation hormones, such as total PYY, CCK, active ghrelin, and obestatin, compared with the levels in the control group.
著者
Tomohiro Yasumitsu Osamu Shimizu Hiroshi Shiratsuchi Yusuke Miyake Yoshiyuki Yonehara
出版者
Nihon University School of Dentistry
雑誌
Journal of Oral Science (ISSN:13434934)
巻号頁・発行日
vol.60, no.4, pp.595-600, 2018 (Released:2018-12-27)
参考文献数
33
被引用文献数
6

The aim of this study was to determine the localization of aquaporin-5 (AQP5), transforming growth factor-β1 (TGF-β1) and laminin during regeneration of the rat submandibular gland. After duct ligation for 7 days, the regenerating glands were collected on days 0, 1, 3, 7, and 14 after ligation release to study the process of regeneration. Immunohistochemical staining revealed apical expression of AQP5 in many acinar cells, strong expression in intercalated ducts (ICDs) of the normal submandibular gland at Day 14, and strong expression in duct-like structures (DLSs) during regeneration from Day 0 to 7. However, a few AQP5-negative acinar cells were detected during regeneration. At Day 0, immunopositivity for TGF-β1 was detected in connective tissue. At Days 3 and 7 during regeneration, TGF-β1 immunostaining was observed in DLSs, which were surrounded by α-smooth muscle actin-positive thickened myoepithelial cells. Laminin staining was strong in the thickened basement membrane of DLSs at Day 3 during regeneration, but weak around acinar cells at Day 14. These findings suggest that TGF-β1 is involved in the environment around DLSs, myoepithelial cells and laminin, that DLSs have the same functional properties as ICDs, and that AQP5-negative acinar cells may be mucous cells.
著者
Hiroki Komiya Kohei Shimizu Kae Ishii Hiroshi Kudo Teinosuke Okamura Kohei Kanno Masamichi Shinoda Bunnai Ogiso Koichi Iwata
出版者
Nihon University School of Dentistry
雑誌
Journal of Oral Science (ISSN:13434934)
巻号頁・発行日
vol.60, no.4, pp.493-499, 2018 (Released:2018-12-27)
参考文献数
23
被引用文献数
28

Pulpitis often causes referred pain in opposing teeth. However, the precise mechanism underlying ectopic pain associated with tooth-pulp inflammation remains unclear. We performed the present study to test the hypothesis that functional interactions between satellite glial cells (SGCs) and trigeminal ganglion (TG) neurons are involved in ectopic orofacial pain associated with tooth-pulp inflammation. Digastric muscle electromyograph (D-EMG) activity elicited by administration of capsaicin into the upper second molar pulp (U2) was analyzed to evaluate noxious reflex responses. D-EMG activity was significantly increased in rats with lower first molar (L1) inflammation relative to saline-treated rats. Significantly increased expression of glial fibrillary acid protein (GFAP), a marker of activated glial cells, and connexin 43 (Cx43), a gap-junction protein, was observed in activated SGCs surrounding U2-innervating TG-neurons after L1-pulp inflammation. Daily administration of Gap26, a Cx43-inhibiting mimetic peptide, into the TG significantly suppressed capsaicin-induced D-EMG activity enhancement and reduced the percentage of fluorogold-labeled (U2-innervated) cells that were surrounded by GFAP-immunoreactive (IR) and Cx43-IR cells after L1-pulp inflammation. These findings indicate that tooth-pulp inflammation induces SGC activation and subsequent spread of SGC activation in the TG via Cx43-containing gap junctions. Thus, remote neuron excitability becomes enhanced in the TG following tooth-pulp inflammation, resulting in ectopic tooth-pulp pain in the contralateral tooth.
著者
Toshiaki Kume Ryo Ito Ryota Taguchi Yasuhiko Izumi Hiroshi Katsuki Tetsuhiro Niidome Yuki Takada-Takatori Hachiro Sugimoto Akinori Akaike
出版者
The Japanese Pharmacological Society
雑誌
Journal of Pharmacological Sciences (ISSN:13478613)
巻号頁・発行日
vol.109, no.1, pp.110-118, 2009 (Released:2009-01-17)
参考文献数
41
被引用文献数
10 12

We investigated the effect of serofendic acid, a neuroprotective substance derived from fetal calf serum, on the morphological changes in cultured cortical astrocytes. Cultured astrocytes developed a stellate morphology with several processes following exposure to dibutylyl cAMP (dbcAMP), a membrane-permeable cAMP analog; 8-Br-cGMP, a membrane-permeable cGMP analog; or phorbol-12-myristate-13-acetate (PMA), a protein kinase C activator. Serofendic acid significantly accelerated the stellation induced by dbcAMP- and 8-Br-cGMP. In contrast, the PMA-induced stellation was not affected by serofendic acid. Next, we attempted to elucidate the mechanism underlying the dbcAMP-induced stellation and explore the site of action of serofendic acid. Both the stellation induced by dbcAMP and the promotional effect of serofendic acid were partially inhibited by KT5720, a specific protein kinase A (PKA) inhibitor. Furthermore, serofendic acid failed to facilitate the stellation induced by Y-27632, an inhibitor of Rho-associated kinase (ROCK). These results indicate that serofendic acid promotes dbcAMP- and 8-Br-cGMP-induced stellation and the promotional effect on dbcAMP-induced stellation is mediated at least partly by the regulation of PKA activity and not by controlling ROCK activity.
著者
Etsuko Shoda Kôhei Kubota Hiroshi Makihara
出版者
JAPANESE SOCIETY OF APPLIED ENTOMOLOGY AND ZOOLOGY
雑誌
Applied Entomology and Zoology (ISSN:00036862)
巻号頁・発行日
vol.38, no.3, pp.339-345, 2003 (Released:2003-11-25)
参考文献数
35
被引用文献数
6 12

The sugi bark borer, Semanotus japonicus, occurs naturally in Honshu, Shikoku, Sado Is., Oki Is., and Yaku Is. in Japan, and its main host tree is the Japanese cedar, Cryptomeria japonica. Because the geographical structure of the morphological characters largely corresponds to the sites of the glacial refugia and the post-Pleistocene dispersal route of the Japanese cedar, the history of the cedar was postulated to have shaped the genetic population structure in the borer. In this study, we used partial sequences from mitochondrial DNA genes, the COI, tRNALeu-UUR and COII to elucidate processes in the geographical structuring of S. japonicus populations. Ten haplotypes were revealed among 52 individuals from four populations that ranged from Iwate to Ehime prefectures. The geographical distribution of these haplotypes was highly structured. Two distinct lineages were detected, which probably represented the Pacific coastal and the Japan Sea side lineages, from the neighbour-joining method and haplotype networking. As haplotypes of both Pacific and Japan Sea lineages were found in the Iwate population, a second contact might have occurred in the Tohoku area. These results suggested that the present genetic structure of S. japonicus was determined by the host's past history.
著者
Tsutomu DOI Toru KIUCHI Akihiro MIHOSHI Hiroshi KITAGAWA Kazuo NISHII
出版者
Japan Society of Civil Engineers
雑誌
INFRASTRUCTURE PLANNING REVIEW (ISSN:09134034)
巻号頁・発行日
vol.12, pp.367-374, 1995-08-31 (Released:2010-06-04)
参考文献数
11
被引用文献数
1 1

本研究は、鉄道沿線の地域イメージとその構造的特徴を分析することを目的としている。.こごでは、関西の私鉄の中から、阪急神戸線、近鉄奈良線、南海高野線の3つの沿線地域を取り上げる。本研究ではまず、これらの沿線に存在する物に関する普通名詞・固有名詞を抽出する。次いで、それぞれの名詞のイメージに類似する名詞をこれらの抽出された名詞群から選ぶという意識調査を実施する。この調査データを用いて、想起率が高いモノ・コトを選定する。また、モノ・コトのイメージにおける類似度の関係をイメージ空間上に布置したイメージマップを作成することにより、沿線イメージの構造の特徴を明らかにする。さらにこれらの特徴を考慮しながら、これからの鉄道沿線の地域づくりにおける基本的課題に言及する。
著者
Hiroshi Matsuo Kaoru Dohi Hirofumi Machida Hideyuki Takeuchi Toshikazu Aoki Hiroyuki Nishimura Masashi Yasutomi Michiharu Senga Takehiko Ichikawa Kentaro Kakuta Yasuhide Mizutani Akiko Tanoue Naoki Isaka Kazuki Oosugi Sukenari Koyabu Masato Sakurai Yoshihisa Fukui Hitoshi Kakimoto Tadafumi Sugimoto Takahiro Ohnishi Tomohiro Murata Eiji Ishikawa Ryuji Okamoto Tomomi Yamada Toru Ogura Yuki Nishimura Takashi Tanigawa Shinsuke Nomura Masakatsu Nishikawa Masaaki Ito
出版者
The Japanese Circulation Society
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
vol.82, no.2, pp.586-595, 2018-01-25 (Released:2018-01-25)
参考文献数
37
被引用文献数
29

Background:The aim of this study was to assess the echocardiographic characteristics of chronic hemodialysis (HD) patients with end-stage renal disease (ESRD) in a multicenter prospective cohort study.Methods and Results:Three hundred and fifteen patients with ESRD (67.9±10.6 years, 47.6% male) on chronic HD for ≥1 year were examined on transthoracic echocardiography, including Doppler-derived aortic valve area (AVA) measurement. Only 11.5% and 3.4% of all patients had normal left ventricular (LV) geometry and normal LV filling pattern, respectively. The majority of patients had aortic and mitral valvular calcification, and approximately 50% of all 315 patients had aortic valve narrowing with AVA <2.0 cm2. Patients were divided into 3 groups according to AVA index tertile: group 1, highest tertile; group 2, middle tertile; and group 3, lowest tertile. Group 3 was older, had a greater cardiothoracic ratio on chest X-ray, higher plasma brain natriuretic peptide and total LV afterload, and lower stroke volume index than the other 2 groups. Age and intact parathyroid hormone (PTH) level were independently associated with low AVA index.Conclusions:Patients with ESRD on chronic HD have a high prevalence of cardiac structural and functional abnormalities including calcified aortic sclerosis. High age and PTH were associated with aortic valve narrowing in these patients.
著者
Takashi Narihiro Masaru Konishi Nobu Tomoyuki Hori Tomo Aoyagi Yuya Sato Tomohiro Inaba Hidenobu Aizawa Hideyuki Tamaki Hiroshi Habe
出版者
Japanese Society of Microbial Ecology · The Japanese Society of Soil Microbiology
雑誌
Microbes and Environments (ISSN:13426311)
巻号頁・発行日
pp.ME18108, (Released:2018-12-22)
被引用文献数
6

The present study characterized the interactions of microbial populations in activated sludge systems during the operational period after an increase in the wastewater flow rate and consequential ammonia accumulation using a 16S rRNA gene sequencing-based network analysis. Two hundred microbial populations accounting for 81.8% of the total microbiome were identified. Based on a co-occurrence analysis, Nitrosomonas-type ammonia oxidizers had one of the largest number of interactions with diverse bacteria, including a bulking-associated Thiothrix organism. These results suggest that an increased flow rate has an impact on constituents by changing ammonia concentrations and also that Nitrosomonas- and Thiothrix-centric responses are critical for ammonia removal and microbial community recovery.
著者
Uehara Shigeo Ihobe Hiroshi
出版者
学術雑誌目次速報データベース由来
雑誌
人類學雜誌 (ISSN:09187960)
巻号頁・発行日
vol.106, no.4, pp.349-369, 1998
被引用文献数
5 17

Censusing was done by direct observation along three survey routes to estimate the distribution and abundance of medium- and large-sized diurnal mammals in the Kasoje area of the Mahale Mountains National Park, western Tanzania between 1995 and 1996. The census area is located within the home range of M Group chimpanzees who have been observed to consume at least 14 species of sympatric mammals. The vegetation along the three census routes was divided into two types of habitat (forest vs. woodland); as a result, six census subunits were distinguished. Preference of habitat by eight species of mammals-red-tailed monkey, blue monkey, yellow baboon, red colobus monkey, bushbuck, blue duiker, warthog, and forest squirrels-has been suggested and their group and/or individual densities have been estimated in at least one census subunit. In 1974, most villagers moved out of the Kasoje area following a government edict and the wild animal population in general appears to have increased in number since then. However, expansion or contraction in distribution of three species of mammals at Kasoje since the 1970s differs from species to species: yellow baboons and warthogs have apparently expanded their ranges while vervet monkeys seem to have contracted theirs. The abundance of red colobus monkeys appears to correspond with the high frequency of colobus hunting by the chimpanzees. However, it should be explained in the future why the second most abundant red-tailed monkeys, another resident arboreal species, have been eaten only infrequently by them. Further accumulation of observations on actual encounters between the chimpanzees and their potential prey is necessary.
著者
Hiroshi OKAJIMA Yuki MINAMI Nobutomo MATSUNAGA
出版者
The Society of Instrument and Control Engineers
雑誌
SICE Journal of Control, Measurement, and System Integration (ISSN:18824889)
巻号頁・発行日
vol.11, no.6, pp.510-516, 2018 (Released:2018-11-22)
参考文献数
18

This study proposes a design method for unilateral control systems with communication rate constraints. In the case where it is necessary to control under a communication rate constraint, the effect of the quantization noise should be minimized using effective signal quantization methods. One of the effective methods for signal quantization is a feedback-type dynamic quantizer. We previously proposed a design method for a dynamic quantizer under communication rate constraints. In this paper, a unilateral control structure is proposed to minimize the effect of the quantization error. The design method for the quantizer is applied to the proposed structure. The effectiveness of the proposed system with the designed quantizer is assessed via numerical examples.
著者
HONDA Hiroshi KANEKO Jun-ichi KONNO Yasuhiko MATSUMOTO Yoshiharu
出版者
日本応用動物昆虫学会
雑誌
Applied entomology and zoology (ISSN:00036862)
巻号頁・発行日
vol.14, no.4, pp.464-468, 1979-11-25
被引用文献数
3

A simple mass-rearing method for the fruit-feeder type yellow peach moth, Dichocrocis punctiferalis GUENEE, was established with an oviposition device and an artificial diet.The oviposition device was a ball-type tea strainer (diam. 8 cm) which contained a small green fruit as an odor source and was wrapped with cheese cloth. The artificial diet consisted of meal powder for mouse, soybean meal powder, dry wood powder, ascorbic acid, agar powder, and water. The average cocoon-yield was 39.4% of eggs inoculated.
著者
Mitsunori Iwasaki Fumie Nishikawa Hiroshi Fukamachi
出版者
The Japanese Society for Horticultural Science
雑誌
The Horticulture Journal (ISSN:21890102)
巻号頁・発行日
pp.UTD-017, (Released:2018-12-07)
被引用文献数
3

Sheet-mulching cultivation during the fruit developmental stage is often carried out to produce high-quality Satsuma mandarin (Citrus unshiu Marc.) and ‘Harehime’ ((‘Kiyomi’ × ‘Osceola’) × ‘Miyagawa-wase’) fruits because they show high Brix% by exposure to drought stress conditions. In this study, we investigated the effect of drought stress on the number of floral buds in ‘Haraguchi-wase’ Satsuma mandarins and ‘Harehime.’ To clarify the relationship between drought stress and the number of floral buds, we applied four different drying treatments to the fruit trees, (i) first-half drying (drying treatment during the first-half of the fruit development stage), (ii) second-half drying (drying treatment during the second-half of the fruit development stage), (iii) all-drying (drying during the full fruit development stage), and (iv) well-watered (non-drought stress during the fruit development stage). The drying treatment was applied to the fruits at ψ max −0.7 to −1.2 MPa at an intensity comparable to proper drought stress for high-quality fruit production according to our previous studies. In ‘Haraguchi-wase,’ the all-drying treatment produced a higher number of floral buds in the following spring season compared with the well-watered treatment, in which the increase in the number of floral buds took place concomitant with the enhancement of CiFT expression in December. As expected, the fruits after all-drying were smaller with a significantly higher Brix% and a similar level of citric acid content, suggesting that drought stress of suitable intensity resulted not only in high-quality fruit production, but also in an increased number of floral buds in the following spring season. The results also demonstrated that the first-half drying caused higher CiFT expression and more inflorescences than in the well-watered plants, while there were no differences in CiFT expression or number of floral buds between the second-half drying and well-watered treatments. These tendencies observed in ‘Haraguchi-wase’ were the same as in ‘Harehime.’ Therefore, the drying treatment during the first-half of fruit development could be an effective method to increase the number of floral buds.
著者
Jun NOMOTO Yoshikatsu SEIKI Masaaki NEMOTO Hiroshi TAKAHASHI Hiroshi TERASHIMA Kyosuke YOKOTA Kosuke KONDO Toshiyuki KANO Syozo GOTO Nobuo SUGO
出版者
The Japan Neurosurgical Society
雑誌
Neurologia medico-chirurgica (ISSN:04708105)
巻号頁・発行日
vol.47, no.4, pp.147-152, 2007 (Released:2007-04-25)
参考文献数
26
被引用文献数
5 7

The clinical characteristics of head trauma were evaluated in 18 wrestlers belonging to a female professional wrestling organization, 13 regular members and five trainees aged 15-34 years. Medical examinations for head trauma were performed in all wrestlers, and wrestlers treated at our emergency outpatient department were clinically evaluated. In addition, the relationships of head trauma with duration of the wrestling career of 1-16 years (mean 8 years) in the regular members, and less than 1 year in the five trainees, and body mass index (BMI) of 21.0-32.0 in the 16 subjects, excluding two trainees, was evaluated. Chronic symptoms were noted in four of the 18 wrestlers with long wrestling careers (16 years in 1, 13 years in 1, and 5 years in 2). Three wrestlers with symptoms immediately after head trauma showed recurrent retrograde amnesia and had low BMI (21.6, 21.6, and 23.1). Five wrestlers were treated at our emergency outpatient clinic, three required hospitalization and two showed intracranial traumatic changes on computed tomography (acute subdural hematoma in 1 and diffuse brain swelling in 1). Head trauma in female professional wrestlers is associated with longer wrestling career and low BMI. Periodic medical examinations are recommended to monitor for signs of head trauma.
著者
Shohei Yamauchi Hiroshi Kajihara
出版者
The Japanese Society of Systematic Zoology
雑誌
Species Diversity (ISSN:13421670)
巻号頁・発行日
vol.23, no.2, pp.183-192, 2018-11-25 (Released:2018-11-25)
参考文献数
51
被引用文献数
3

Three new species of macrodasyidan gastrotrichs are described from the coasts of Hokkaido, northern Japan. Cephalodasys mahoae sp. nov. differs from congeners in having the oocytes developing from posterior to anterior. Turbanella cuspidata sp. nov. is characterized by a pair of small, ventrolateral projective organs at U06. Turbanella lobata sp. nov. is unique among congeners in having paired lateral lobes on the neck. We inferred the phylogenetic position of C. mahoae sp. nov. by maximum-likelihood analysis and Bayesian inference based on 18S rRNA, 28S rRNA, and COI gene sequences from 28 species of macrodasyids. In the resulting trees, C. mahoae sp. nov. formed a clade with an unidentified species of Cephalodasys Remane, 1926, but not with C. turbanelloides (Boaden, 1960).