著者
Hiroyo Kamio Hitoshi Maruyama Nozomi Ito Mako Kunieda Ayaka Chiba Yorimitsu Furukawa
出版者
The Japanese Society of Physical Fitness and Sports Medicine
雑誌
The Journal of Physical Fitness and Sports Medicine (ISSN:21868131)
巻号頁・発行日
vol.11, no.1, pp.29-34, 2022-01-25 (Released:2022-01-14)
参考文献数
18
被引用文献数
1

Pelvic floor muscle training has been reported to be effective in preventing and improving urinary incontinence. Patients must learn to perform pelvic floor muscle contractions without pushing down the pelvic floor by contracting other muscle groups. This study aimed to determine the effect of maximal-effort contraction of the hip adductor and abductor muscles on the pelvic floor of young, healthy women. For these experiments, 23 healthy nulliparous women performed unilateral maximal-effort isometric contractions of the abductor and adductor hip muscles in a supine position. Simultaneously, the movement of the bladder’s posterior surface was measured using an ultrasonic imaging device. The displacement of the bladder base during maximal-effort contraction of the hip adductor/abductor muscles was calculated based on changes in the distance between the abdominal wall and the bladder base at rest. The results demonstrated that the bladder base significantly descended during maximal-effort isometric contraction of hip adduction/abduction. The maximal-effort isometric hip adduction/abduction muscle strength positively correlated with bladder base descent. These results indicated that isometric contraction of the hip adduction/abduction muscles under maximum effort pushed the pelvic floor downward. In pelvic floor muscle training, when the adductor and abductor muscles of the hip joint are contracted with maximum effort, the pelvic floor muscles cannot learn contraction and may inhibit movement.
著者
Ryuta NAKAE Yasuo MURAI Akio MORITA Shoji YOKOBORI
出版者
The Japan Neurosurgical Society
雑誌
Neurologia medico-chirurgica (ISSN:04708105)
巻号頁・発行日
pp.2022-0018, (Released:2022-04-22)
参考文献数
72
被引用文献数
11

Coagulopathy is a common sequela of traumatic brain injury. Consumptive coagulopathy and secondary hyperfibrinolysis are associated with hypercoagulability. In addition, fibrinolytic pathways are hyperactivated as a result of vascular endothelial cell damage in the injured brain. Coagulation and fibrinolytic parameters change dynamically to reflect these pathologies. Fibrinogen is consumed and degraded after injury, with fibrinogen concentrations at their lowest 3-6 h after injury. Hypercoagulability causes increased fibrinolytic activity, and plasma levels of D-dimer increase immediately after traumatic brain injury, reaching a maximum at 3 h. Owing to disseminated intravascular coagulation in the presence of fibrinolysis, the bleeding tendency is highest within the first 3 h after injury, and often a condition called "talk and deteriorate" occurs. In neurointensive care, it is necessary to measure coagulation and fibrinolytic parameters such as fibrinogen and D-dimer routinely to predict and prevent the development of coagulopathy and its negative outcomes. Currently, the only evidence-based treatment for traumatic brain injury with coagulopathy is tranexamic acid in the subset of patients with mild-to-moderate traumatic brain injury. Coagulation and fibrinolytic parameters should be closely monitored, and treatment should be considered on a patient-by-patient basis.
著者
近藤 哲夫
出版者
山梨大学
雑誌
若手研究(B)
巻号頁・発行日
2010

本研究の目的はエピジェネティクス修飾により甲状腺癌細胞にTTF-1 を誘導する有効的な方法の確立、TTF-1 による甲状腺機能分子の再誘導の検証、TTF-1の腫瘍抑制効の解明である。結果として一過性発現、安定発現細胞株ともにTTF-1の強制発現のみによっては甲状腺機能分子の発現や甲状腺ホルモン産生を誘導することはできなかった。一方でTTF-1発現誘導により甲状腺癌細胞の増殖抑制がおこることが確認された。cDNAマイクロアレイによってTTF-1発現誘導により有意に増加する遺伝子群と減少する遺伝子群が確認された。 本研究の成果によりTTF-1には腫瘍抑制的機能が存在することが示唆された。
著者
韓 雪 長谷川 智子 外山 紀子
出版者
公益社団法人 日本心理学会
雑誌
心理学研究 (ISSN:00215236)
巻号頁・発行日
vol.93, no.3, pp.177-187, 2022 (Released:2022-08-25)
参考文献数
26

There are cultural differences in childcare practices in preschools, reflecting beliefs and values about children, childcare, and education. The COVID-19 pandemic exposed normally hidden cultural, ethnic, and historical issues. Mealtime is particularly restricted by droplet spread of COVID-19. Cultural differences in thoughts related to meals became evident in the response to this critical situation caused by the pandemic. This study examined how preschool mealtime has changed due to COVID-19 in Japan and China. A questionnaire survey was conducted from September 2020 to January 2021. This study included 191 Japanese preschools and 179 Chinese preschools. Various infection countermeasures were taken and mealtime practices changed drastically in both countries. In Japan, preschool mealtime is regarded as a socially essential event, for example, chatting while eating; whereas in China, nutrition and hygiene are considered more important. Possibly, because of such differences in mealtime conceptions, the impact of the spread of COVID-19 appeared to be substantial in Japan compared to China. Based on the obtained results, cultural differences in preschool education were discussed.
著者
高橋 希衣
出版者
北海道大学大学院文学研究科
雑誌
研究論集 (ISSN:13470132)
巻号頁・発行日
vol.13, pp.181-204, 2013-12-20

Aus der Sicht der Beschreibung und Erklarung von Universalit at und Sprachspezifit at werden zur Zeit sehr aktiv Forschungen betrieben,sprachtypologisch nicht verwandte Sprachen kontrastiv zu untersuchen. Jedoch muss man feststellen, dass sich die Forschungen in der deutsch-japanischen kontrastiven Phonetik und Phonologie nicht entsprechend dynamisch entwickeln wie der allgemeine Trend; dies betrifft besonders die noch immer uneinheitlichen phonetisch-phonologischen Kana-Aussprachebezeichnungen in deutschjapanischen Worterbuchern, die anstatt unter Verwendung des IPA (Internationales Phonetisches Alphabet) haufig mit alteren und unnaturlichen phonetischen Notationen dargestellt werden. Im vorliegenden Beitrag wird ein neues System fur die phonetischphonologische Beschreibung von Kana-Aussprachebezeichnungen fur deutsche Laute vorgeschlagen. Als grundlegendes Prinzip wird bei der Systematisierung der Kana-Aussprachebezeichnungen die Treue zu den originalen Lauten des Deutschen verfolgt. Dar uber hinaus soll diachronisch berucksichtigt werden, dass als ein Teil der deutschen Sprache auch die praktizierten und akzeptierten Formen der Standardaussprache einem standigen Wandel unterliegen.